Bayesian Analysis最新文献

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Bayesian Data Augmentation for Partially Observed Stochastic Compartmental Models 部分观测随机区室模型的贝叶斯数据增强
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-06-17 DOI: 10.1214/23-ba1398
Shuying Wang, S. Walker
{"title":"Bayesian Data Augmentation for Partially Observed Stochastic Compartmental Models","authors":"Shuying Wang, S. Walker","doi":"10.1214/23-ba1398","DOIUrl":"https://doi.org/10.1214/23-ba1398","url":null,"abstract":"Deterministic compartmental models are predominantly used in the modeling of infectious diseases, though stochastic models are considered more realistic, yet are complicated to estimate due to missing data. In this paper we present a novel algorithm for estimating the stochastic SIR/SEIR epidemic model within a Bayesian framework, which can be readily extended to more complex stochastic compartmental models. Specifically, based on the infinitesimal conditional independence properties of the model, we are able to find a proposal distribution for a Metropolis algorithm which is very close to the correct posterior distribution. As a consequence, rather than perform a Metropolis step updating one missing data point at a time, as in the current benchmark Markov chain Monte Carlo (MCMC) algorithm, we are able to extend our proposal to the entire set of missing observations. This improves the MCMC methods dramatically and makes the stochastic models now a viable modeling option. A number of real data illustrations and the necessary mathematical theory supporting our results are presented.","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43825210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Consistent and Scalable Bayesian Joint Variable and Graph Selection for Disease Diagnosis Leveraging Functional Brain Network 基于功能脑网络的疾病诊断一致可扩展贝叶斯联合变量和图选择
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-03-14 DOI: 10.1214/23-ba1376
Xuan Cao, Kyoungjae Lee
{"title":"Consistent and Scalable Bayesian Joint Variable and Graph Selection for Disease Diagnosis Leveraging Functional Brain Network","authors":"Xuan Cao, Kyoungjae Lee","doi":"10.1214/23-ba1376","DOIUrl":"https://doi.org/10.1214/23-ba1376","url":null,"abstract":"We consider the joint inference of regression coefficients and the inverse covariance matrix for covariates in high-dimensional probit regression, where the predictors are both relevant to the binary response and functionally related to one another. A hierarchical model with spike and slab priors over regression coefficients and the elements in the inverse covariance matrix is employed to simultaneously perform variable and graph selection. We establish joint selection consistency for both the variable and the underlying graph when the dimension of predictors is allowed to grow much larger than the sample size, which is the first theoretical result in the Bayesian literature. A scalable Gibbs sampler is derived that performs better in high-dimensional simulation studies compared with other state-of-art methods. We illustrate the practical impact and utilities of the proposed method via a functional MRI dataset, where both the regions of interest with altered functional activities and the underlying functional brain network are inferred and integrated together for stratifying disease risk.","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48543252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scalable Approximate Bayesian Computation for Growing Network Models via Extrapolated and Sampled Summaries. 通过外推和采样摘要为成长网络模型提供可扩展的近似贝叶斯计算。
IF 4.9 2区 数学
Bayesian Analysis Pub Date : 2022-03-01 Epub Date: 2020-12-08 DOI: 10.1214/20-ba1248
Louis Raynal, Sixing Chen, Antonietta Mira, Jukka-Pekka Onnela
{"title":"Scalable Approximate Bayesian Computation for Growing Network Models via Extrapolated and Sampled Summaries.","authors":"Louis Raynal, Sixing Chen, Antonietta Mira, Jukka-Pekka Onnela","doi":"10.1214/20-ba1248","DOIUrl":"10.1214/20-ba1248","url":null,"abstract":"<p><p>Approximate Bayesian computation (ABC) is a simulation-based likelihood-free method applicable to both model selection and parameter estimation. ABC parameter estimation requires the ability to forward simulate datasets from a candidate model, but because the sizes of the observed and simulated datasets usually need to match, this can be computationally expensive. Additionally, since ABC inference is based on comparisons of summary statistics computed on the observed and simulated data, using computationally expensive summary statistics can lead to further losses in efficiency. ABC has recently been applied to the family of mechanistic network models, an area that has traditionally lacked tools for inference and model choice. Mechanistic models of network growth repeatedly add nodes to a network until it reaches the size of the observed network, which may be of the order of millions of nodes. With ABC, this process can quickly become computationally prohibitive due to the resource intensive nature of network simulations and evaluation of summary statistics. We propose two methodological developments to enable the use of ABC for inference in models for large growing networks. First, to save time needed for forward simulating model realizations, we propose a procedure to extrapolate (via both least squares and Gaussian processes) summary statistics from small to large networks. Second, to reduce computation time for evaluating summary statistics, we use sample-based rather than census-based summary statistics. We show that the ABC posterior obtained through this approach, which adds two additional layers of approximation to the standard ABC, is similar to a classic ABC posterior. Although we deal with growing network models, both extrapolated summaries and sampled summaries are expected to be relevant in other ABC settings where the data are generated incrementally.</p>","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":"17 1","pages":"165-192"},"PeriodicalIF":4.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541316/pdf/nihms-1803183.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33497387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bayesian Inference on Hierarchical Nonlocal Priors in Generalized Linear Models 广义线性模型中层次非局部先验的贝叶斯推理
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-ba1350
Xuan Cao, Kyoungjae Lee
{"title":"Bayesian Inference on Hierarchical Nonlocal Priors in Generalized Linear Models","authors":"Xuan Cao, Kyoungjae Lee","doi":"10.1214/22-ba1350","DOIUrl":"https://doi.org/10.1214/22-ba1350","url":null,"abstract":"Variable selection methods with nonlocal priors have been widely studied in linear regression models, and their theoretical and empirical performances have been reported. However, the crucial model selection properties for hierarchical nonlocal priors in high-dimensional generalized linear regression have rarely been investigated. In this paper, we consider a hierarchical nonlocal prior for high-dimensional logistic regression models and investigate theoretical properties of the posterior distribution. Specifically, a product moment (pMOM) nonlocal prior is imposed over the regression coefficients with an Inverse-Gamma prior on the tuning parameter. Under standard regularity assumptions, we establish strong model selection consistency in a high-dimensional setting, where the number of covariates is allowed to increase at a subexponential rate with the sample size. We implement the Laplace approximation for computing the posterior probabilities, and a modified shotgun stochastic search procedure is suggested for efficiently exploring the model space. We demonstrate the validity of the proposed method through simulation studies and an RNA-sequencing dataset for stratifying disease risk.","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49089074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bayesian Learning of Graph Substructures 图子结构的贝叶斯学习
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-BA1338
W. V. Boom, M. Iorio, A. Beskos
{"title":"Bayesian Learning of Graph Substructures","authors":"W. V. Boom, M. Iorio, A. Beskos","doi":"10.1214/22-BA1338","DOIUrl":"https://doi.org/10.1214/22-BA1338","url":null,"abstract":"Graphical models provide a powerful methodology for learning the conditional independence structure in multivariate data. Inference is often focused on estimating individual edges in the latent graph. Nonetheless, there is increasing interest in inferring more complex structures, such as communities, for multiple reasons, including more effective information retrieval and better interpretability. Stochastic blockmodels offer a powerful tool to detect such structure in a network. We thus propose to exploit advances in random graph theory and embed them within the graphical models framework. A consequence of this approach is the propagation of the uncertainty in graph estimation to large-scale structure learning. We consider Bayesian nonparametric stochastic blockmodels as priors on the graph. We extend such models to consider clique-based blocks and to multiple graph settings introducing a novel prior process based on a Dependent Dirichlet process. Moreover, we devise a tailored computation strategy of Bayes factors for block structure based on the Savage-Dickey ratio to test for presence of larger structure in a graph. We demonstrate our approach in simulations as well as on real data applications in finance and transcriptomics.","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44413832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Inference for Bayesian Nonparametric Models with Binary Response Data via Permutation Counting 二值响应数据下贝叶斯非参数模型的置换计数推理
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-ba1353
Dennis Christensen
{"title":"Inference for Bayesian Nonparametric Models with Binary Response Data via Permutation Counting","authors":"Dennis Christensen","doi":"10.1214/22-ba1353","DOIUrl":"https://doi.org/10.1214/22-ba1353","url":null,"abstract":"","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46134883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Posterior Predictive Checking for Partially Observed Stochastic Epidemic Models 部分观测随机流行病模型的后验预测检验
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-ba1336
Georgios Aristotelous, T. Kypraios, P. O’Neill
{"title":"Posterior Predictive Checking for Partially Observed Stochastic Epidemic Models","authors":"Georgios Aristotelous, T. Kypraios, P. O’Neill","doi":"10.1214/22-ba1336","DOIUrl":"https://doi.org/10.1214/22-ba1336","url":null,"abstract":"","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47907200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gaussian Variational Approximations for High-dimensional State Space Models 高维状态空间模型的高斯变分逼近
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-ba1332
M. Quiroz, D. Nott, R. Kohn
{"title":"Gaussian Variational Approximations for High-dimensional State Space Models","authors":"M. Quiroz, D. Nott, R. Kohn","doi":"10.1214/22-ba1332","DOIUrl":"https://doi.org/10.1214/22-ba1332","url":null,"abstract":"","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47451543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Normal Approximation for Bayesian Mixed Effects Binomial Regression Models 贝叶斯混合效应二项回归模型的正态逼近
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-ba1312
Brandon Berman, W. Johnson, Weining Shen
{"title":"Normal Approximation for Bayesian Mixed Effects Binomial Regression Models","authors":"Brandon Berman, W. Johnson, Weining Shen","doi":"10.1214/22-ba1312","DOIUrl":"https://doi.org/10.1214/22-ba1312","url":null,"abstract":". Bayesian inference for generalized linear mixed models implemented with Markov chain Monte Carlo (MCMC) sampling methods have been widely used. In this paper, we propose to substitute a large sample normal approximation for the intractable full conditional distribution of the latent effects (of size k ) in order to simplify the computation. In addition, we develop a second approximation involving what we term a sufficient reduction (SR). We show that the full conditional distributions for the model parameters only depend on a small, say r (cid:2) k , dimensional function of the latent effects, and also that this reduction is asymptotically normal under mild conditions. Thus we substitute the sampling of an r dimensional multivariate normal for sampling the k dimensional full conditional for the latent effects. Applications to oncology physician data, to cow abortion data and simulation studies confirm the reasonable performance of the proposed approximation method in terms of estimation accuracy and computational speed.","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42285358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Multi-Armed Bayesian Ordinal Outcome Utility-Based Sequential Trial with a Pairwise Null Clustering Prior 具有成对零聚类先验的多臂贝叶斯有序结果效用序贯试验
IF 4.4 2区 数学
Bayesian Analysis Pub Date : 2022-01-01 DOI: 10.1214/22-ba1316
A. Chapple, Yussef Bennani, Meredith Clement
{"title":"A Multi-Armed Bayesian Ordinal Outcome Utility-Based Sequential Trial with a Pairwise Null Clustering Prior","authors":"A. Chapple, Yussef Bennani, Meredith Clement","doi":"10.1214/22-ba1316","DOIUrl":"https://doi.org/10.1214/22-ba1316","url":null,"abstract":". A multi-armed trial based on ordinal outcomes is proposed that lever-ages a flexible non-proportional odds cumulative logit model and numerical utility scores for each outcome to determine treatment optimality. This trial design uses a Bayesian clustering prior on the treatment effects that encourages the pairwise null hypothesis of no differences between treatments. A group sequential design is proposed to determine which treatments are clinically different with an adaptive decision boundary that becomes more aggressive as the sample size or clinical significance grows, or the number of active treatments decreases. A simulation study is conducted for 3 and 5 treatment arms, which shows that the design has superior operating characteristics (family wise error rate, generalized power, average sample size) compared to utility designs that do not allow clustering, a frequentist proportional odds model, or a permutation test based on empirical mean utilities.","PeriodicalId":55398,"journal":{"name":"Bayesian Analysis","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42427985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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