Current Opinion in Cardiology最新文献

Developing a professional and career identity: it's a journey to enjoy. 培养专业和职业身份：这是一个享受的旅程。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-03-29 DOI: 10.1097/HCO.0000000000001219

Paul A Checchia

引用次数: 0

The burden of innovation in the pediatric heart center. 儿童心脏中心的创新负担。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-05-02 DOI: 10.1097/HCO.0000000000001224

Andrea Torzone, Alexandra Birely

{"title":"The burden of innovation in the pediatric heart center.","authors":"Andrea Torzone, Alexandra Birely","doi":"10.1097/HCO.0000000000001224","DOIUrl":"10.1097/HCO.0000000000001224","url":null,"abstract":"Purpose of review: The purpose of this review is to elucidate the growing complexity involved in providing pediatric cardiac care in the contemporary era of innovation. Aiming to highlight the phenomenon of chronic critical illness in a pediatric heart center, this review outlines the burdens placed on those caring for these uniquely challenging patients and poses considerations for alleviating those burdens.Recent findings: As care advancements drive improved survival for children with heart disease, heart centers face a growing population of chronically critically ill patients with high resource utilization and uncertain trajectories. Preterm infants, single ventricles, and complex heart failure patients require significant interventions and expertise. Their lengthy courses challenge care delivery systems and resources, in addition to placing significant emotional and cognitive burdens on the multidisciplinary teams.Summary: The growing population of chronically critically ill cardiac patients are some of the most challenging both at the system level and on the team members. While undertaking innovative therapies, we must recognize that survival as an outcome cannot be separated from associated costs of achieving that outcome; the resultant burdens of innovation cannot be ignored. Heart centers must take a proactive stance in optimizing care for children with prolonged illness while also addressing the needs of those who care for them.","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":" ","pages":"265-274"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of coronary artery calcification detection in tailoring patient care, personalized risk assessment, and prevention of future cardiac events. 冠状动脉钙化检测在定制患者护理、个性化风险评估和预防未来心脏事件中的作用。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-03-11 DOI: 10.1097/HCO.0000000000001216

Rohan Kankaria, Abhishek Gami, Jaideep Patel

引用次数: 0

Pulmonary hypertension in 2025: next steps? 2025年肺动脉高压：下一步？

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-05-02 DOI: 10.1097/HCO.0000000000001228

Kinjal Parikh

引用次数: 0

Near infrared spectroscopy in the pediatric cardiac intensive care unit: accurately interpreting the data. 近红外光谱在儿童心脏重症监护病房：准确地解释数据。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-02-12 DOI: 10.1097/HCO.0000000000001204

Ilias Iliopoulos, Saul Flores, Rohit Loomba

{"title":"Near infrared spectroscopy in the pediatric cardiac intensive care unit: accurately interpreting the data.","authors":"Ilias Iliopoulos, Saul Flores, Rohit Loomba","doi":"10.1097/HCO.0000000000001204","DOIUrl":"10.1097/HCO.0000000000001204","url":null,"abstract":"Purpose of review: Near infrared spectroscopy (NIRS) has been increasingly adopted as standard monitoring in postoperative care of pediatric cardiac patients. Several reports have established its association with both markers of perfusion and adverse outcomes. The correlation with markers of perfusion is not strong and exhibits wide limit of agreement, making the determination of critical thresholds and its integration in treatment algorithms challenging.Recent findings: A growing body of literature support the use of NIRS for hemodynamic monitoring in pediatric cardiac patients. Recent reports corroborate prior findings of weak to moderate correlation of NIRS with markers of global and regional perfusion and confirm its association with adverse outcomes. The challenge of lack of treatment thresholds remains, limiting clinical utility. Evidence of improvement of outcomes with the use of NIRS remains limited.Summary: NIRS is a useful monitor of regional and global perfusion and can inform management decisions but cannot be used as the sole decision-making tool. Large, randomized studies are needed to define its use as decision making tool and facilitate its integration in treatment algorithms.","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":" ","pages":"282-289"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated C-reactive protein and cardiovascular risk. c反应蛋白升高与心血管疾病风险。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-02-27 DOI: 10.1097/HCO.0000000000001215

Jia Ee Chia, Song Peng Ang

{"title":"Elevated C-reactive protein and cardiovascular risk.","authors":"Jia Ee Chia, Song Peng Ang","doi":"10.1097/HCO.0000000000001215","DOIUrl":"10.1097/HCO.0000000000001215","url":null,"abstract":"Purpose of review: This review critically examines the evolving role of C-reactive protein (CRP) in cardiovascular disease (CVD), addressing its pathogenesis and relationship with various CVDs including coronary artery disease (CAD), heart failure, and atrial fibrillation.Recent findings: CRP is mechanistically implicated in endothelial dysfunction, oxidative stress, and plaque destabilization. Recent studies demonstrate that lipid-lowering agents (statins, bempedoic acid) and anti-inflammatory therapies (canakinumab, colchicine) reduce CRP levels and improve outcomes in CAD. In heart failure, elevated CRP predicts adverse events, though evidence on phenotypes varies, and novel therapies (glucagon-like peptide-1 agonists, sodium-glucose cotransporter-2 inhibitors) lower CRP independently of weight loss. For atrial fibrillation, CRP correlates with postoperative incidence and recurrence postablation, though data remain inconsistent. Guidelines offer differing opinion with the American College of Cardiology and the American Heart Association (ACC/AHA) guidelines cautiously endorsing CRP for risk stratification in intermediate-risk individuals, while European guidelines advise against its routine use for primary prevention, reflecting unresolved questions about CRP's additive value.Summary: CRP remains a pivotal inflammation biomarker in CVD, yet its causal role and clinical applicability require clarification. While CRP-guided therapies show promise, discrepancies in guidelines highlight the need for robust trials to determine whether targeting CRP directly improves outcomes. Future research should focus on CRP's pathophysiological mechanisms and validate its utility in personalized CVD management.","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":" ","pages":"237-243"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From C-reactive protein to climate change: risk predictors for cardiovascular diseases beyond low-density lipoprotein cholesterol. 从c反应蛋白到气候变化：低密度脂蛋白胆固醇以外心血管疾病的风险预测因子。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-06-05 DOI: 10.1097/HCO.0000000000001232

Debabrata Mukherjee, Dimitri P Mikhailidis

引用次数: 0

Neurodevelopmental outcomes in congenital heart disease: modifiable and nonmodifiable substrates. 先天性心脏病的神经发育结局：可改变和不可改变的基础。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-05-13 DOI: 10.1097/HCO.0000000000001218

Kelly Wolfe, Shabnam Peyvandi

{"title":"Neurodevelopmental outcomes in congenital heart disease: modifiable and nonmodifiable substrates.","authors":"Kelly Wolfe, Shabnam Peyvandi","doi":"10.1097/HCO.0000000000001218","DOIUrl":"10.1097/HCO.0000000000001218","url":null,"abstract":"Purpose of review: Neurodevelopmental impairments are the most common comorbidity among children, adolescents, and adults with congenital heart disease (CHD). Despite significant advances in operative and perioperative care resulting in increased survival, neurodevelopmental impairments remain prevalent in this population. Neurodevelopmental impairments, though subtle, can have a major impact on quality of life, attainment of independence and societal contribution. In this review, we summarize current knowledge on neurodevelopmental outcomes in the CHD population, including neuroimaging findings, known risk factors and opportunities to optimize outcomes.Recent findings: Several risk factors have been identified contributing to neurodevelopmental impairments across the lifespan. These include risk factors originating in the prenatal period and new risk factors that are acquired in adulthood. The risk factors encompass several categories, including genetic abnormalities, aberrant cardiovascular physiology, environmental factors, social determinants of health and mental health. Many risk factors can be considered modifiable, though large multicenter studies identifying the most salient risk factors for neurodevelopmental impairment are lacking.Summary: In this review, we identify potentially modifiable risk factors for neurodevelopmental impairment in the CHD population that can be studies in future neuroprotective clinical trials.","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":" ","pages":"259-264"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Climate change and cardiovascular risk. 气候变化和心血管风险。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-02-12 DOI: 10.1097/HCO.0000000000001207

Song Peng Ang, Jia Ee Chia

{"title":"Climate change and cardiovascular risk.","authors":"Song Peng Ang, Jia Ee Chia","doi":"10.1097/HCO.0000000000001207","DOIUrl":"10.1097/HCO.0000000000001207","url":null,"abstract":"Purpose of review: This review explores the complex relationship between climate change and cardiovascular health. It examines the mechanisms through which climate change impacts cardiovascular risk, highlights recent findings on regional trends, and discusses mitigation strategies.Recent findings: Climate change significantly contributes to cardiovascular morbidity and mortality through mechanisms such as temperature extremes, air pollution, and food insecurity. Heatwaves increase risks of dehydration, electrolyte imbalance, and acute cardiovascular events, while cold spells exacerbate myocardial stress and pollution-related cardiovascular risks. Air pollution, including fine particulate matter (PM2.5), induces systemic inflammation, endothelial dysfunction, and atherosclerosis. Emerging data highlight regional variations, with urbanization exacerbating risks in Asia-Pacific and Middle Eastern populations, while extreme heat and cold challenge resilience in Europe and Latin America. Studies also link socioeconomic stress from climate-induced displacement and resource shortages to chronic cardiovascular conditions. Notably, urban greening and air quality regulations demonstrate potential for reducing cardiovascular risks.Summary: Climate change amplifies cardiovascular risks through diverse mechanisms, disproportionately affecting vulnerable populations. Targeted strategies, including public health campaigns, sustainable urban planning, and technological innovations, can mitigate these risks. Advances in generative artificial intelligence and big data analytics offer opportunities to tailor interventions and enhance predictive modeling. A multidisciplinary approach integrating public health, environmental science, and clinical expertise is critical to addressing these challenges. Urgent action is required to mitigate the long-term cardiovascular impacts of climate change and foster resilient health systems globally.","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":" ","pages":"244-250"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypertension after solid-organ transplantation: special considerations for management. 实体器官移植后高血压：处理的特殊考虑。

IF 2 4区医学

Current Opinion in Cardiology Pub Date : 2025-07-01 Epub Date: 2025-05-05 DOI: 10.1097/HCO.0000000000001230

Jason Feliberti, Amit Alam, Christopher Maulion

{"title":"Hypertension after solid-organ transplantation: special considerations for management.","authors":"Jason Feliberti, Amit Alam, Christopher Maulion","doi":"10.1097/HCO.0000000000001230","DOIUrl":"10.1097/HCO.0000000000001230","url":null,"abstract":"Purpose of review: Hypertension is one of the most common comorbidities affecting patients after solid organ transplantation. Here we review the mechanisms leading to hypertension, along with common practices in terms of medical management. Glucagon-like peptide-1 receptor (GLP-1R) agonists, baroreflex therapy, and renal denervation are common interventions utilized prior to heart transplant. Special considerations for their management throughout the perioperative and postoperative period are covered here.Recent findings: Most common medical management includes utilization of calcium channel blockers, followed by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. GLP-1R agonists have shown significant benefit in recent cardiovascular outcome trials. Preoperative management centers around risks associated with slowed gastric emptying, while reinitiation after heart transplant must take into consideration initiation and tolerance of immunosuppressive therapies. Baroreflex activation therapy has been approved for therapy of heart failure, with many patients proceeding to heart transplant. The device is frequently deactivated after transplantation, with little published experience regarding reinitiation of therapy after heart transplant. There is renewed interest in renal denervation as a treatment for refractory hypertension. The incidence of hypertension after heart transplant in those patients that have undergone previous renal denervation remains unknown, however there is limited experience with its use after renal transplant.Summary: Further studies are required to elucidate optimal medical management of hypertension following heart transplantation. GLP-1R agonists, baroreflex activation therapy, and renal denervation are emerging therapies prior to transplant that require further investigation.","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":" ","pages":"193-198"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0