Current Opinion in Otolaryngology & Head and Neck Surgery最新文献

Long-term complications of extracranial pericranial flaps in skull base reconstruction. 颅外颅周皮瓣在颅底重建中的长期并发症。

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-10-29 DOI: 10.1097/MOO.0000000000001021

Kelly E Daniels, Joseph Mocharnuk, Zainab Balogun, Georgios A Zenonos, Paul A Gardner, Carl H Snyderman, Eric W Wang

{"title":"Long-term complications of extracranial pericranial flaps in skull base reconstruction.","authors":"Kelly E Daniels, Joseph Mocharnuk, Zainab Balogun, Georgios A Zenonos, Paul A Gardner, Carl H Snyderman, Eric W Wang","doi":"10.1097/MOO.0000000000001021","DOIUrl":"10.1097/MOO.0000000000001021","url":null,"abstract":"Purpose of review: Nasoseptal flaps are a frequently used and well characterized means of reconstruction following endoscopic endonasal approach surgery (EEA). However, there are alternative means of reconstruction, including the extracranial pericranial flap (ePCF), that while used infrequently fulfill a specialized need in larger or salvage reconstructions. This review aims to better characterize long-term outcomes using ePCF where there is currently a paucity of objective data on use and outcomes.Recent findings: A traditional pericranial flap involves elevating and rotating the flap through a craniotomy defect to reconstruct defects of the ventral skull base. The ePCF is implemented without performing a craniotomy, and instead tunnels the flap through a bony opening created at the level of the nasion. This review presents outcomes in a large single-center cohort of patients with ePCFs to better characterize the short- and long-term success, risks, and complications of this reconstructive method.Summary: Long-term follow-up demonstrates that obstruction of the frontal sinus outflow may occur but rarely requires surgical intervention. ePCF are a reasonable alternative to consider in cases where local tissue would be insufficient, is not available, or has already failed. There is a low risk of flap complications.","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":"43-49"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Olfactory outcomes in skull base surgery. 颅底手术的嗅觉效果

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.1097/MOO.0000000000001023

Sanjena Venkatesh, Jennifer E Douglas

{"title":"Olfactory outcomes in skull base surgery.","authors":"Sanjena Venkatesh, Jennifer E Douglas","doi":"10.1097/MOO.0000000000001023","DOIUrl":"10.1097/MOO.0000000000001023","url":null,"abstract":"Purpose of review: This review examines the impact of skull base surgery on olfactory function, a critical yet often overlooked aspect of postoperative quality of life. As surgical techniques continue to evolve, understanding their impact on olfaction is key to optimizing patient outcomes.Recent findings: The relationship between skull base surgery and olfactory function continues to be debated in the literature. With the adoption of transnasal surgical approaches, a significant concern has been its impact on olfaction. Prior studies have shown evidence of olfactory dysfunction following transnasal skull base surgery, though these findings are not universal. A particular area of discussion involves the use of the pedicled nasoseptal flap, which has demonstrated potentially negative short-term olfactory impacts. Additional concerns surround flap design (olfactory strip preservation) and technique of flap harvest (cold knife versus electrocautery). Evidence suggests that olfactory strip preservation may effectively maintain postoperative olfactory performance, while cold knife techniques offer no clear advantage over electrocautery.Summary: The inconsistencies in the literature underscore the need for standardized, large-scale studies that directly compare surgical techniques to better understand the impact of transnasal skull base surgery on olfaction. This is essential to optimizing surgical outcomes and improving patient quality of life postoperatively.","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":"31-42"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic rhinosinusitis and asthma: epidemiology, pathophysiology, morbidity, treatment.

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-11-27 DOI: 10.1097/MOO.0000000000001022

Marlene M Speth, David T Liu, Gerold Besser, Ahmad R Sedaghat

引用次数: 0

Postoperative management following endoscopic skull base surgery. 内窥镜颅底手术后的术后管理。

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-09-11 DOI: 10.1097/MOO.0000000000001010

Domen Vozel, Jure Urbančič

引用次数: 0

Imaging approach for fungal sinusitis. 真菌性鼻窦炎的成像方法。

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-09-30 DOI: 10.1097/MOO.0000000000001018

Richard Dagher, Susana Calle, Kim O Learned

引用次数: 0

Recent developments in olfactory neuroblastoma research.

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-11-27 DOI: 10.1097/MOO.0000000000001027

Anthony Ghanem, John B Finlay, David W Jang, Bradley J Goldstein, Ralph Abi Hachem

{"title":"Recent developments in olfactory neuroblastoma research.","authors":"Anthony Ghanem, John B Finlay, David W Jang, Bradley J Goldstein, Ralph Abi Hachem","doi":"10.1097/MOO.0000000000001027","DOIUrl":"10.1097/MOO.0000000000001027","url":null,"abstract":"Purpose of review: Olfactory neuroblastoma (ONB) is a rare malignancy originating from olfactory neuroepithelial cells. Given its uncommon nature and complex clinical presentation, this comprehensive review highlights recent findings and treatment approaches for advancing clinical practice and research.Recent findings: Recent literature emphasizes significant advancements in the genomic profiling and molecular classification of ONB. Emerging targeted therapies include somatostatin analogs and programmed death-ligand 1 (PD-L1) inhibitors. In addition, the development of genetically engineered mouse models has provided valuable platforms for testing new treatment strategies, revealing similarities between ONB and small cell lung cancer, which may inform future therapeutic approaches.Summary: These findings have profound implications on clinical practice. Improved diagnostic accuracy through advanced imaging and genomic profiling in addition to identifying specific mutations for targeted therapy can lead to personalized treatments of patients with ONB. Developments in genetically engineered mouse models and multiinstitutional collaborative efforts are vital for advancing research and standardizing molecular testing. The integration of advanced imaging techniques, genomic profiling, and targeted therapies holds promise for improving patient outcomes and understanding this rare malignancy.","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":"50-55"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Invasive fungal rhinosinusitis: current evidence and research opportunities. 侵袭性真菌性鼻炎：现有证据与研究机会。

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-07-18 DOI: 10.1097/MOO.0000000000000993

Jenny Ji, Lauren T Roland

引用次数: 0

Editorial introductions.

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2025-01-02 DOI: 10.1097/MOO.0000000000001025

引用次数: 0

Fibro-osseous lesions of the sinonasal tract: a contemporary review.

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2025-02-01 Epub Date: 2024-10-03 DOI: 10.1097/MOO.0000000000001017

Kartik Motwani, Avraham E Adelman, Nikita Chapurin

{"title":"Fibro-osseous lesions of the sinonasal tract: a contemporary review.","authors":"Kartik Motwani, Avraham E Adelman, Nikita Chapurin","doi":"10.1097/MOO.0000000000001017","DOIUrl":"10.1097/MOO.0000000000001017","url":null,"abstract":"Purpose of review: Fibro-osseous lesions (FOL) are benign, slow-growing lesions that are often incidentally discovered in the sinonasal cavity. They may necessitate surgical resection in patients with postobstructive sinusitis, or in cases of cranial nerve and orbital compression. We examine the recent advancements in otolaryngology relating to diagnostic characteristics and treatments for FOL, with emphasis on new technologies to improve outcomes and reduce recurrence.Recent findings: We discuss distinguishing characteristics across FOL subtypes, including osteomas, fibrous dysplasia, and ossifying fibroma. Recent literature encompasses clinical case series and animal model studies examining mechanistic, diagnostic, and therapeutic findings in FOL. Recent advancements include emerging pharmacological therapies, development of imaging guidance for surgical planning, and focus on the importance of complete surgical resection for improved outcomes.Summary: Management of most FOL may be approached by endoscopic techniques, harnessing recent improvements in image guidance and surgical innovation. Improved diagnostic imaging, including the use of 3-D surgical planning, has been shown to enhance treatment outcomes. Improved understanding of the genetic and pathophysiological characteristics of FOL could further reveal targeted therapies, reducing recurrence and improving patient quality of life.","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":"13-19"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ewing's sarcoma of the head and neck: differential diagnosis, treatment and outcomes.

IF 1.9 4区医学

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2024-12-27 DOI: 10.1097/MOO.0000000000001032

Deepa Nair, Linu Thomas, Vasundhara Patil

{"title":"Ewing's sarcoma of the head and neck: differential diagnosis, treatment and outcomes.","authors":"Deepa Nair, Linu Thomas, Vasundhara Patil","doi":"10.1097/MOO.0000000000001032","DOIUrl":"https://doi.org/10.1097/MOO.0000000000001032","url":null,"abstract":"Purpose of review: Ewing's sarcoma is a small round-cell tumour typically arising in the bones, and only rarely affecting soft tissues. These are rarely seen in the head and neck comprising 1-9% of all cases, making management of these tumours a challenge. This review aims to review the current literature to update the current diagnostic and treatment options in head and neck Ewing's sarcoma.Recent findings: The tumour is characterized in most cases by recurrent balanced translocations between the EWSR1 gene on chromosome 22 and genes belonging to the ETS family of transcription factors. Its main driver is the reciprocal translocation between the EWSR1 and FLI1 genes (EWSR1:FLI1). Molecular techniques for the detection of FET/ETS fusions are widely used to confirm the diagnosis. Newer entities like adamantinoma-like Ewing sarcoma have been recently described. The chemotherapy protocols also have changed following Euro Ewing 2012 study. Reclassification of margin status may help standardize treatment in these cases.Summary: Head and neck Ewings sarcoma is an uncommon tumour, mainly affecting paediatric/adolescent male individuals. Histopathological diagnosis is often challenging and immunohistochemical markers and/or molecular tests are generally used. Several molecular techniques for the detection of FET/ETS fusions are widely used to confirm the diagnosis. Management of Ewing's consists of a multimodal treatment regimen, including surgical resection and/or local radiotherapy, as well as intensive multiagent chemotherapy. Increase in age and the presence of distant metastasis are associated with shorter survival times.","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0