Global Nest Journal最新文献

Anastesi Inhalasi pada Tikus (Rattus Norvegicus) Menggunakan Eter dan Kloroform 老鼠吸入的麻醉(Rattus Norvegicus)使用乙醚和氯仿

4区环境科学与生态学

Global Nest Journal Pub Date : 2025-08-05 DOI: 10.62383/ikg.v2i3.2228

Haryanto Haryanto, Alfani Zahrah Suci, Ahni Elena Aprilia, Ainun Mutia Putri, Sahratul Wilda, Harianti Harianti, Purnamasari Purnamasari

{"title":"Anastesi Inhalasi pada Tikus (Rattus Norvegicus) Menggunakan Eter dan Kloroform","authors":"Haryanto Haryanto, Alfani Zahrah Suci, Ahni Elena Aprilia, Ainun Mutia Putri, Sahratul Wilda, Harianti Harianti, Purnamasari Purnamasari","doi":"10.62383/ikg.v2i3.2228","DOIUrl":"https://doi.org/10.62383/ikg.v2i3.2228","url":null,"abstract":"This study aimed to compare the inhalation anesthetic profiles of ether and chloroform in white rats (Rattus norvegicus) using a modern pharmacological approach. Five healthy male rats (8–10 weeks old) were randomly divided into three groups: ether, chloroform, and control (ketoprofen). The main parameters observed were the onset time of loss of the righting reflex and the duration until its recovery. In theory, ether works by enhancing GABAergic transmission and inhibiting NMDA channels, thus having a slow but stable induction effect (IKAPI, 2009; Arqom, 2023). In contrast, chloroform works by stabilizing the neuronal membrane through activation of the K₂P TREK-1 channel and inhibition of Na⁺/Ca²⁺ currents, resulting in rapid induction with a short duration (Pavel et al., 2020). The experimental results support this theory: chloroform showed an average onset of 167.83 seconds and an anesthesia duration of 84.67 seconds, while ether had a slower onset (307.17 seconds) but a longer duration (169.33 seconds). The difference between the two was statistically significant (ANOVA, p<0.05). The coefficient of variation for chloroform was nearly four times higher than that of ether, indicating that ether provides a more consistent anesthetic effect across individuals. These findings are consistent with previous studies, such as Fathiyah & Anretha's (2023) report on the variability of chloroform effects and the results of in vivo amethyst anesthesia studies (Aprira, 2022; Genta et al., 2021). Overall, ether is more suitable for medium-term procedures requiring stable anesthesia, while chloroform is suitable for short interventions requiring rapid induction. This study emphasizes the importance of controlled inhalation environments, adequate sample sizes, and chamber standardization to enhance the external validity of the results.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"2 3","pages":"256-267"},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://journal.lpkd.or.id/index.php/IKG/article/download/2228/2486","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147911127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Occurrence and drivers of Antibiotics in the rural-urban River Network: A case study of Hongze Lake basin, China 城乡河网抗生素的发生及驱动因素——以洪泽湖流域为例

4区环境科学与生态学

Global Nest Journal Pub Date : 2025-03-12 DOI: 10.30955/gnj.07181

{"title":"Occurrence and drivers of Antibiotics in the rural-urban River Network: A case study of Hongze Lake basin, China","authors":"","doi":"10.30955/gnj.07181","DOIUrl":"https://doi.org/10.30955/gnj.07181","url":null,"abstract":"The massive use of antibiotics and the consequent antibiotic pollution have become a major risk to river ecosystems, water quality, and human health. In this study, 28 antibiotics were analyzed in the&nbsp;rural-urban&nbsp;river water of Suzhou City, the inflow rivers of Hongze Lake.&nbsp;The total concentration of antibiotics in the&nbsp;rural-urban river was nd-85.87 ng/L, mainly containing veterinary antibiotics, quinolones, and tetracyclines. The distribution of antibiotics was found to be closely related to the population density and the development of the breeding industry along the bank through structural equation model and correlation analysis. Meanwhile, the human activities&nbsp;(70%), livestock and poultry breeding&nbsp;(30%)&nbsp;were the main sources of antibiotics in the study area through the principal component analysis-multiple linear regression (PCA-MLR) source analysis. Finally, the risk assessment was carried out by the Risk Quotient&nbsp;(RQ) method,&nbsp;and&nbsp;indicated that&nbsp;antibiotics pose a low risk to plant and invertebrates&nbsp;,but Ofloxacin, Ciprofloxacin, Erythromycin,&nbsp;Norfloxacin, and&nbsp;Chlortetracycline posed a&nbsp;mid ecological risk to algae. This work provide a valuable data set across the rural-urban river network and revealed the antibiotic contamination profile. Prevention and management to reduce the antibiotic inputs are needed for the rural-urban zones.&nbsp;","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://journal.gnest.org/system/files/2025-03/gnest_07181_in%20press.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147913157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aplicaciones de la proteómica en el diagnóstico de cáncer de mama: avances y limitaciones 蛋白质组学在乳腺癌诊断中的应用：进展和局限性

4区环境科学与生态学

Global Nest Journal Pub Date : 2024-07-22 DOI: 10.70165/cglobal.v9i2.428

Katheryn Nathaly Condo Paredes, Álvaro Sebastián Ron Mora

{"title":"Aplicaciones de la proteómica en el diagnóstico de cáncer de mama: avances y limitaciones","authors":"Katheryn Nathaly Condo Paredes, Álvaro Sebastián Ron Mora","doi":"10.70165/cglobal.v9i2.428","DOIUrl":"https://doi.org/10.70165/cglobal.v9i2.428","url":null,"abstract":"El cáncer de mama es una enfermedad sumamente compleja y heterogénea que tiene como característica un crecimiento descontrolado de las células pertenecientes al tejido mamario Es esencial identificar biomarcadores más sensibles. Una reciente respuesta ha sido el uso de la tecnología proteómica que ha aportado una excelente ayuda a la caracterización de nuevos biomarcadores moleculares mediante la medición de los perfiles de proteínas. Analizar la aplicación de la proteómica en el diagnóstico de cáncer de mama sus Avances y Limitaciones. Para la realización del artículo se empleó una revisión bibliográfica encaminada en una investigación en revistas científicas de gran relevancia, repositorios y base de datos de salud como Scopus, Embase, Science Direct, ProQuest, PubMed, Scielo, Medline. Los documentos revisados brindan información acerca de la aplicación de las diferentes técnicas proteómicas en el diagnóstico de cáncer de mama, muchos de sus avances, pero también las limitaciones que surgen a lo largo de este estudio. Se resaltan muchas de las pruebas de laboratorio que se pueden realizar para un diagnóstico y manejo del cáncer de mama. La aplicación de la proteómica en el diagnóstico del cáncer de mama ha representado un avance prometedor hacia la detección temprana y personalizada de esta enfermedad.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"9 2","pages":"370-380"},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://conocimientoglobal.org/revista/index.php/cglobal/article/download/428/284","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147896915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trace Metals Pollution in Ambient Air of Urban and Rural Coastal Environments 城乡沿海环境空气中微量金属污染

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-14 DOI: 10.30955/gnj.005174

{"title":"Trace Metals Pollution in Ambient Air of Urban and Rural Coastal Environments","authors":"","doi":"10.30955/gnj.005174","DOIUrl":"https://doi.org/10.30955/gnj.005174","url":null,"abstract":"Air pollution in coastal areas will have a different pattern from mountainous areas due to different wind patterns during the day and night. The city of Semarang, as a representation of urban areas, and Jepara Regency, as a representation of the rural regions, were chosen for this sampling. 24-h fine particulate matter (PM2.5) was collected within 3 months of sampling. In this study, seven metal elements derived from this PM2.5 were quantified using ICP MS. The analytical method used is a descriptive analysis of the obtained metal element data, enrichment factor (EF), Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) modeling and sources pollutant estimation. The results of the study showed that the stannum (Sn) metal was found in almost all study locations. Sn, K, and Fe are the dominant metals found in urban areas, whereas, in rural areas, only the Sn metal is quite abundant. Nevertheless, the results of EF calculations show that the most significant enrichment in both villages and cities is Sn. Allegedly, this enrichment occurred because of dense activity in the transportation sector and metal industry in urban areas, which brought metals to three villages in Jepara Regency. This research can be used as the main reference in determining health risks associated with metal pollution in atmospheric particulate matter.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"24 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134901500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diatom records in sediments for eutrophication process of Lake Xian'nv, China since the mid-20th century 20世纪中期以来咸女湖富营养化过程沉积物中的硅藻记录

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-13 DOI: 10.30955/gnj.005247

{"title":"Diatom records in sediments for eutrophication process of Lake Xian'nv, China since the mid-20th century","authors":"","doi":"10.30955/gnj.005247","DOIUrl":"https://doi.org/10.30955/gnj.005247","url":null,"abstract":"To well understand the eutrophication process for inland lakes where more lands had been used for agriculture and industry without adequate environmental protections, 9 surface sediments and 1 core sediment in Lake Xian’nv which was located in the middle of Jiangxi Province were chosen. Combined with 210Pb and 137Cs geochronology, nutrient index including total nitrogen (TN), total phosphorus (TP), total organic carbon (TOC), Carbon nitrogen ratio (C/N), diatoms assembles and TDI index of eutrophic diatoms were compared quantitatively and conducted to elucidate the eutrophication process using statistical methods. The results showed a total of 155 years from 1863 to 2018 were recorded from the entire sediment core. The nutrient level in 23 centimeters below the surface of the sediment core where was synchronized with reservoir construction indicated TN, TP, TOC, and Carbon nitrogen ratio had been gradually increased since the construction of Dam. In surface sediments, the three diatoms with higher average relative abundance were Achnanthidium minutissimum, Navicula Bory, and Aulacoseira granulata with a value of 54.2 %, 29.4 %, and 15.3 % respectively. Significant changes of the diatom communities from 1955 to 2009 had been recorded, where diatom communities could be classified into four distinct periods. In the first few years after the reservoir was built, the dominant diatoms were epiphytic and benthic diatom communities represented by Navicula cincta、Fragilaria ulna, and Cocconeis placentula in zone I on the bottom floor covered from 1955 to 1961. However, planktonic diatom communities were dominant after 1983 which were mainly constituted by Aulacoseira alpigena、Cyclostephanos dubius、Cyclotella meneghiniana, and Cyclotella radiosa . Both TDI index of eutrophic diatoms and Principal Component Analysis (PCA) revealed the succession from benthic diatoms to planktonic diatoms and changes in nutrient levels.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"60 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136348562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatiotemporal variability of heavy metals concentration in an industrialized estuarine-bay ecosystem in Northern Persian Gulf 波斯湾北部工业化河口湾生态系统重金属浓度时空变异特征

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-10 DOI: 10.30955/gnj.005416

{"title":"Spatiotemporal variability of heavy metals concentration in an industrialized estuarine-bay ecosystem in Northern Persian Gulf","authors":"","doi":"10.30955/gnj.005416","DOIUrl":"https://doi.org/10.30955/gnj.005416","url":null,"abstract":"This study aimed to evaluate the pollution level of Ni, Pb, Cd, V, and Hg in the sediments of Musa Estuary and its four main tributaries namely Majidieh, Zangi, Semaili, and Merimos (collectively known as Mahshahr estuaries) in summer and winter 2019 using sediment quality indices. In each tributary, 4 stations were chosen to represent the estuary condition. One control point was also considered at the mouth of the estuary (17 stations in total). 51 sediment samples were collected using the Van Wien Hydrobius grab sampler and measurements were performed utilizing the ICP-MASS device. The heavy metals concentration was ordered as Ni&gt; Pb&gt; Cd&gt; V&gt; Hg and tributaries followed the order of Majidiyeh&gt; Samaili&gt; Zangi&gt; Merimos&gt; Musa's mouth (control point) in terms of heavy metal concentration in both seasons. Heavy metal concentrations were positively and significantly correlated with electrical conductivity and pH (P &lt;0.05). The potential ecological risk (Er) was low for Ni, Pb, and V, moderate for Cd (except for Musa's mouth in summer (27.33)). Hg had low risk in Zangi Tributary and Musa's mouth in summer and medium risk in other tributaries in winter. The ecological risk index (RI) showed considerable risk in Zangi Tributary and Musa's mouth in both seasons and high risk in Merimos, Majidieh, and Samaili tributaries. According to the pollution load index (PLI), the sediments of Mahshahr estuaries showed no pollution in summer and moderate pollution in Majidiyeh and Smaili tributaries in winter. The Nemro Integrated Pollution Index ranged from 8.62 to 20.04 in summer and 9.15 to 21.53 in winter Mahshahr estuaries which indicate its high pollution potential. The findings of this research and those of previous studies alarm increasing levels of heavy metals’ content in the sediments of Mahshahr estuaries over the past years.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"109 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135137277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anaerobic Digestion of Corn Stover Pretreated with Sulfuric Acid in Different Soaking Durations 不同浸泡时间下硫酸预处理玉米秸秆的厌氧消化

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-10 DOI: 10.30955/gnj.005229

引用次数: 0

Effect of coconut shell ash as an additive on the properties of green concrete 椰壳灰分作为添加剂对绿色混凝土性能的影响

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-10 DOI: 10.30955/gnj.005413

{"title":"Effect of coconut shell ash as an additive on the properties of green concrete","authors":"","doi":"10.30955/gnj.005413","DOIUrl":"https://doi.org/10.30955/gnj.005413","url":null,"abstract":"Concrete is the broadly adopted composite material in the construction arena. The growing need for cost-effective housing is resulting in the depletion of environmental resources such as river sand and gravel, which are essential components in the manufacture of concrete. However, the manufacturing of cement has been proven to have a negative impact on the environment because it contributes to the carbon footprint. The resolution of these environmental issues can be achieved through the implementation of sustainable solutions. This article explores the potential application of coconut shell ash as a substitute for cement in green concrete. Coconut shells (CS) are inevitable by-products derived from the agricultural sector. Coconut shell ash (CSA) was obtained through the combustion of coconut shells. The CSA is substituted by a range of 0 to 20% by weight of cement with a gradual 2.5% increase. The test findings concluded that 12.5% of CSA mix attained the maximum compressive strength. The durability results were found satisfactory in comparison with the normal concrete. The specimens were exposed to different temperatures (i.e., 100 °C, 200 °C, and 300 °C) for a consistent duration of one hour. The CSA concrete exhibited improved residual strength and weight reduction compared to conventional concrete.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"103 21","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135138168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Air Pollution Monitoring Approach using Atomic Orbital Search Algorithm with Deep Learning Driven 基于深度学习驱动的原子轨道搜索算法的空气污染监测方法

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-10 DOI: 10.30955/gnj.005373

{"title":"Air Pollution Monitoring Approach using Atomic Orbital Search Algorithm with Deep Learning Driven","authors":"","doi":"10.30955/gnj.005373","DOIUrl":"https://doi.org/10.30955/gnj.005373","url":null,"abstract":"Air pollution is a major reason for health-related issues and weather changes, one of humanity's most dangerous problems. It is the most crucial environmental issue in the 21st century and has attracted global attention. These challenges are exacerbated by an overabundance of automobiles, industrial output pollution, transportation fuel consumption, and energy generation. Therefore, air pollution prediction was developed vital. Air pollution monitoring is the procedure of analyzing and measuring the air quality in a certain place to develop the levels of several pollutants and contaminants present. Monitoring air pollution is vital to understand its sources, and effects on the environment and human health, and for executing methods for mitigating its effects. Deep learning (DL) approaches are employed for air pollution predicting methods. Therefore, this study develops an Atomic Orbital Search Algorithm with a Deep Learning-Driven Air Pollution Monitoring (AOSADL-APM) approach. The purpose of the AOSADL-APM technique is to predict and classify the presence of air pollutants. In the presented AOSADL-APM technique, the min-max normalization approach is applied for data pre-processing. For air pollution prediction and classification, the AOSADL-APM technique applies deep long short-term memory (DLSTM) methodology. To enhance the performance of the AOSADL-APM technique, the AOSA-based hyperparameter tuning has been developed. The simulation results of the AOSADL-APM technique were tested using the benchmark dataset. The widespread outcome analyzed the greater solution of the AOSADL-APM algorithm compared to existing approaches.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"115 44","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135138508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green Synthesis of ZnO Nanoparticles Using Moringa Oleifera Leaf Extract for Efficient Photocatalytic Degradation of Organic Dyes 辣木叶提取物绿色合成纳米ZnO光催化降解有机染料

4区环境科学与生态学

Global Nest Journal Pub Date : 2023-11-07 DOI: 10.30955/gnj.005411

引用次数: 0