Health Services Research最新文献

{"title":"Effects of Continuous Medicaid Coverage in 2020-2023 on Children's Health Insurance Coverage, Access to Care, Health Services Use by Type, and Health Status.","authors":"Wei Lyu, George L Wehby","doi":"10.1111/1475-6773.70034","DOIUrl":"https://doi.org/10.1111/1475-6773.70034","url":null,"abstract":"<p><strong>Objective: </strong>To examine the effects of continuous Medicaid coverage in 2020-2023 under the Families First Coronavirus Response Act (FFCRA) on children's health insurance coverage, access to care, likelihood of using healthcare services by type, and health status.</p><p><strong>Study setting and design: </strong>A difference-in-differences event study compares outcomes pre and post FFCRA between states without pre-FFCRA continuity provisions (treatment group) and those that required 12-month continuous coverage (control group).</p><p><strong>Data sources and analytical sample: </strong>The main sample includes 122,901-126,117 children (depending on outcome) aged 1-17 years with family income below 300% of federal poverty level from the 2016-2023 National Survey of Children's Health.</p><p><strong>Primary findings: </strong>After FFCRA, public coverage increased in treatment states in 2020, 2021, and 2022 by 4.1 (95% CI: 0.004, 8.3), 4.7 (95% CI, 0.4, 9.0), and 5.4 (95% CI: 2.0, 8.7) percentage points, respectively, relative to control states. Privately purchased coverage declined in 2020 by 3.5 (95% CI: -5.3, -1.7) percentage points. The likelihood of having a usual place for sick care increased by 3.6 (95% CI: 0.5, 6.8) percentage points in 2021, and the likelihood of unmet care needs decreased by 1.7 (95% CI: -2.8, -0.7) and 2.4 (95% CI: -3.8, -1.0) percentage points in 2021 and 2022. The likelihood of excellent/very good health increased by 2.5 (95% CI: 0.4, 4.5), 3.8 (95% CI: 0.7, 6.8), and 2.7 (95% CI: 0.4, 5.0) percentage points in 2020, 2021, and 2023, respectively. There were no changes in the likelihood of medical, preventive, mental health, specialist, and emergency department visits and hospital admissions.</p><p><strong>Conclusions: </strong>Medicaid continuity under the FFCRA increased the children's public coverage rate. Despite potential switching from private coverage, there is evidence for reductions in unmet care needs and improved health status. Findings provide insights into potential effects of recent federal requirements that all states provide 12-month Medicaid continuity for children.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70034"},"PeriodicalIF":3.2,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Provider and Organizational Factors Impacting Routine Cancer Screening Among Older Medicaid Enrollees.","authors":"Adriana Corredor-Waldron, Ann M Nguyen, Jose Nova, Yiming Ma, Joel C Cantor, Anita Y Kinney, Jennifer Tsui","doi":"10.1111/1475-6773.70030","DOIUrl":"https://doi.org/10.1111/1475-6773.70030","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the conditional association between provider and organizational factors and routine cancer screening for older Medicaid enrollees before and during the COVID-19 pandemic.</p><p><strong>Study setting and design: </strong>This study analyzed pre-pandemic (2018/2019; n = 110,882) and pandemic (2020/2021; n = 107,451) cohorts of New Jersey (NJ) Medicaid enrollees aged 50-75. Using linear probability models, we evaluated how provider and organizational characteristics, including interactions with pandemic years, influenced screening for breast, cervical, colorectal, and lung cancers. Models controlled for enrollees' demographic and clinical characteristics and geographic factors.</p><p><strong>Data sources and analytic sample: </strong>Claims data from the 2016-2021 NJ Medicaid Management Information System were linked to Medicare Provider and Specialty files. The sample included Medicaid enrollees with an assigned primary care provider and no prior cancer diagnosis.</p><p><strong>Principal findings: </strong>Higher patient panel sizes were consistently associated with increased screening for breast (20.4%, 95% confidence interval (CI): 13.9%-26.8%), cervical (24.1%, 95% CI: 16.6%-31.5%), and lung cancer (63.1%; 95% CI: 17.4%-108.6%) during the pandemic. Obstetrician-gynecologist providers were linked to higher screening rates for breast (50.6%, 95% CI: 41.6%-59.5%) and cervical cancers (70.5%, 95% CI: 52.3%-88.9%), even during the pandemic. Female providers improved screening rates for breast (7.6%, 95% CI: 2.8%-12.3%), cervical (3.8%, 95% CI: 0.10%-7.5%), and colorectal cancer (5.8%, 95% CI: -2.7%-14.4%) among female enrollees. Provider age was unrelated to breast, cervical, or colorectal screening; however, in 2021, lung cancer screening was 23% lower for patients of clinicians aged 62 and above.</p><p><strong>Conclusions: </strong>Large group practices effectively maintained breast and cervical cancer screening during the pandemic while exhibiting mixed results for colorectal and lung cancers. Provider characteristics such as gender and specialty also significantly impacted screening rates. Supporting large practices and addressing barriers in smaller practices are key to improving cancer prevention, especially during crises.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70030"},"PeriodicalIF":3.2,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organizational Perspectives on the Public Charge Rule and Health Care Access for Latino Immigrants in California.","authors":"Clara B Barajas, Maria-Elena De Trinidad Young, Arturo Vargas Bustamante, Imelda Padilla-Frausto, Rosa Elena Garcia, Brent A Langellier, Dylan H Roby, Jim P Stimpson, Ninez A Ponce, Jan M Eberth, Mark Stehr, Alexander N Ortega","doi":"10.1111/1475-6773.70032","DOIUrl":"https://doi.org/10.1111/1475-6773.70032","url":null,"abstract":"<p><strong>Objective: </strong>To examine how mis- and disinformation about the Public Charge Ground of Inadmissibility final rule (\"public charge rule\") influences health care access for Latino immigrants in California as seen through the perspectives of leaders in health-serving organizations.</p><p><strong>Study setting and design: </strong>This qualitative study included semi-structured interviews with healthcare and community-based organizational leaders serving Latino immigrants in California. Viswanath et al.'s structural influence model of communication and equity guided the analyses and interpretation of the findings.</p><p><strong>Data sources and analytic sample: </strong>Between May 2024 and April 2025, primary data were collected from 31 organizations, resulting in 32 semi-structured interviews with 38 participants. Interviews were conducted via Zoom and transcribed verbatim. Researchers coded the data based on recurring themes using Dedoose software.</p><p><strong>Principal findings: </strong>Participants identified the public charge rule as a significant barrier to health care access for Latino immigrants. The policy has discouraged many Latinos from accessing public benefits, particularly the state's Medicaid and Supplemental Nutrition Assistance Program. In addition, immigrants' trusted sources of information (e.g., family, friends, and attorneys) were often misinformed about the policy, which amplified confusion and fear. Organizations respond by providing accurate information and connecting individuals with reliable resources to clarify that using public benefits would not necessarily result in being classified as a public charge. However, most efforts focused on education rather than directly countering mis- and disinformation.</p><p><strong>Conclusions: </strong>Healthcare and community-based organizations offer unique perspectives as trusted intermediaries who help Latino immigrant families navigate health care and public benefits. Their close daily interactions reveal how misinformation about the public charge rule deters families from accessing essential services and makes it more challenging for organizations to fulfill their missions. These insights underscore the need for culturally responsive outreach and policy solutions that address information gaps and the climate of fear affecting community health.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70032"},"PeriodicalIF":3.2,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Affordable Care Act's Long-Term Services and Supports Rebalancing Programs.","authors":"Ari Ne'eman","doi":"10.1111/1475-6773.70018","DOIUrl":"https://doi.org/10.1111/1475-6773.70018","url":null,"abstract":"<p><strong>Objective: </strong>To understand the impact of the Balancing Incentive Program (BIP) and Community First Choice State Plan Option (CFC) on LTSS rebalancing as measured by the size of and balance between the community and institutional LTSS workforces.</p><p><strong>Study setting and design: </strong>Using a stacked difference-in-difference design, this paper evaluates the impact of BIP and CFC on the number of LTSS workers per 1000 persons 65+, the number of community LTSS workers per 1000 persons 65+, the number of institutional LTSS workers per 1000 persons 65+, and the proportion of all LTSS workers employed in community-based settings. We also test the impact of BIP's performance targets by separately estimating program effects for states that had yet to meet BIP rebalancing targets upon entering the program.</p><p><strong>Data sources and analytical sample: </strong>Workforce and population data from the American Community Survey from 2005 to 2021.</p><p><strong>Principal findings: </strong>This study finds that BIP resulted in a 13.24% (95% CI: 1.14%, 25.34%) increase in the size of the HCBS workforce in participating states, while finding no statistically significant effect for CFC (1.51%, 95% CI: -12.77%, 15.79%). The point estimate for growth in the HCBS workforce caused by BIP is twice as large in states bound by performance targets embedded within the BIP program (16.18%, 95% CI: 4.01%, 28.35%) as it is in states that are not (8.25%, 95% CI: -9.77%, 26.27%), suggesting that additional federal funding may be more effective when tied to performance targets for states. Neither program had a statistically significant effect on the size of the institutional workforce (BIP: 5.04%, 95% CI: -2.38%, 12.44%; CFC: 0.24%, 95% CI: -6.52%, 7.00%).</p><p><strong>Conclusion: </strong>Federal policymakers seeking to increase investment in HCBS should ensure that additional funds are tied to measurable performance targets, incentivizing states to undertake expansions in HCBS that would not otherwise have taken place.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70018"},"PeriodicalIF":3.2,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Number and Overlap of Diagnostic Information for Risk Adjustment for Dually Enrolled Veterans in Medicaid.","authors":"Patrick N O'Mahen, Chase S Eck, Suja S Rajan, Cheng Rebecca Jiang, Christine Yang, Laura A Petersen","doi":"10.1111/1475-6773.70031","DOIUrl":"https://doi.org/10.1111/1475-6773.70031","url":null,"abstract":"<p><strong>Objective: </strong>To measure discrepancies in risk adjustment scores using only Medicaid or Veterans Health Administration (VA) diagnoses for Veterans dually enrolled in VA and Medicaid.</p><p><strong>Study setting and design: </strong>Veterans aged 18-64 enrolled in the VA and Medicaid for at least one full calendar year during 2017-2020. We compared the number and overlap of annual diagnoses derived from VA and Medicaid data. We also calculated Charlson, Elixhauser, and Centers for Medicare and Medicaid Hierarchical Condition Categories Version 21 (CMS-V21) risk scores using VA-only, Medicaid-only, and combined VA-Medicaid data for each person-year. We used intraclass correlations within risk measures to compare scores across risk measures.</p><p><strong>Data sources and analytic sample: </strong>We used data from the VA's Assistant Deputy Undersecretary for Health's (ADUSH) enrollment files regarding age and VA Priority Group to select our cohort of VA enrollees. We used T-MSIS Analytic Files (TAF) and the Demographics and Enrollment (DE) file to determine Medicaid enrollment.</p><p><strong>Principal findings: </strong>Our study cohort contained 183,018 dual-enrollees with service-connected disabilities representing 405,318 person years and 219,977 dual enrollees without service-connected disabilities (531,948 person years). On average, service-connected individuals had 9.1 fewer diagnoses from Medicaid-only data than from VA-only data (95% Confidence Interval (CI): [9.0, 9.1]) and 5.0 fewer for non-service-connected Veterans (95% CI: [4.9, 5.1]). Intraclass correlations between VA-only data and combined VA-Medicaid scores had higher correlations for Charlson (0.816 vs. 0.591 for service connected, 0.722 vs. 0.638 for non-service connected) and Elixhauser (0.818 vs. 0.609 for service-connected, 0.723 to 0.702 non-service-connected) scores, while Medicaid-only scores had higher correlations for CMS V21 (0.756 vs. 0.666 for service-connected, 0.795 to 0.542 for non service-connected).</p><p><strong>Conclusions: </strong>Medicaid and VA data represent non-overlapping diagnoses data in three common risk scores. Researchers should consider combining records to calculate disease burden for dual-enrolled Veterans to ensure complete capture of risk.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70031"},"PeriodicalIF":3.2,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enumerating the Oncology Specialist Workforce in Medicaid: Applying a Triangulated Approach.","authors":"Anushree Vichare, Mandar Bodas, Clese Erikson, Pavani Chalasani, Qian Eric Luo","doi":"10.1111/1475-6773.70029","DOIUrl":"https://doi.org/10.1111/1475-6773.70029","url":null,"abstract":"<p><strong>Objective: </strong>To develop a novel method for enumerating the oncology specialist workforce triangulating taxonomy codes, board certification data, and clinical diagnosis codes in Medicaid claims, and to describe oncology specialists' Medicaid participation, their patient panels, and ascertain the concentration of types of cancers they treated.</p><p><strong>Study setting and design: </strong>We identified oncology specialists using multiple data sources and conducted an exploratory analysis of their patient panels using multi-state Medicaid claims data. We used cluster analysis of diagnosis code patterns in claims to accurately determine the concentration of cancers by site in oncologists' panels.</p><p><strong>Data sources and analytic sample: </strong>We used data from 2016 to 2020 Transformed Medicaid Statistical Information System (T-MSIS) and physician certification data. We included board-certified oncology physicians specialized in medical and radiation oncology, hematology, hematology-oncology, gynecologic oncology, and pediatric hematology-oncology. To identify surgical oncologists, we combined board certification and Medicare Provider Enrollment, Chain, and Ownership System (PECOS) data. We identified Medicaid beneficiaries with malignant neoplasms by cancer site using ICD-10-CM codes.</p><p><strong>Principal findings: </strong>In 2016, about 89% of oncology specialists participated in Medicaid; this proportion decreased slightly to 86% in 2020. The trends in Medicaid participation and the mean number of beneficiaries differed by oncology specialty. Panels of pediatric hematologist-oncologists had a higher proportion of Hispanic Medicaid beneficiaries with cancer (26%) relative to other specialists. Cluster analysis identified 565 out of 5395 medical oncologists that had high concentration (at least 58%) of breast cancer patients in their panels. Among 6970 hematologist-oncologists, 269 had high concentrations in breast cancer (more than 60%), and 944 in hematological cancer (more than 59%).</p><p><strong>Conclusions: </strong>Our study offers a pragmatic approach to understand the oncology specialist workforce available to Medicaid beneficiaries. The findings provide baseline estimates to track this workforce and provide policymakers with an opportunity to develop targeted strategies to improve access to cancer care.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70029"},"PeriodicalIF":3.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors That Motivate Provider Switching: The Patients' Perspective.","authors":"Onyi Dillibe, Rahul Singh, Norman A Johnson","doi":"10.1111/1475-6773.70028","DOIUrl":"https://doi.org/10.1111/1475-6773.70028","url":null,"abstract":"<p><strong>Objective: </strong>To generate evidence regarding the specific critical incidents that prompt patients to switch care providers.</p><p><strong>Study setting and design: </strong>Building on existing work on customer switching behavior, we applied the critical incident technique (CIT) to the health services research context and analyzed primary data obtained from 555 US-based patients who reported switching providers between 2018 and 2022 to develop a typology of the critical incidents that prompt patients to switch healthcare providers.</p><p><strong>Data sources and analytic sample: </strong>Data were obtained from an online survey of adult US-based patients who reported switching primary care providers (PCPs) for non-insurance-related reasons. The survey was conducted from August to September 2022 using a quota sampling approach.</p><p><strong>Principal findings: </strong>We found eight critical incident categories associated with patient switching: service encounter failures, pricing, competitor attraction, inconvenience, core service failures, involuntary switching, breakdown in shared decision-making, and service environment perception.</p><p><strong>Conclusion: </strong>We offer explanations and suggest potentially useful evidence-based strategies for further investigation.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70028"},"PeriodicalIF":3.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and Physician Burnout in the United States: Cross-Sectional and Longitudinal Evidence From a National Survey.","authors":"Anuja L Sarode, Xiaochu Hu, Michael J Dill","doi":"10.1111/1475-6773.70003","DOIUrl":"https://doi.org/10.1111/1475-6773.70003","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of the COVID-19 pandemic on physician burnout.</p><p><strong>Study setting and design: </strong>This observational study spanned from 2019 to 2022, involving active US physicians from various settings. We applied logistic regression to cross-sectional data to examine the associations between COVID-19-affected aspects of physicians' work and practice and physician burnout, and used repeated measures of ANOVA on longitudinal data to determine changes in burnout before and during COVID-19.</p><p><strong>Data sources and analytic sample: </strong>Both cross-sectional (n = 5917) and longitudinal data (n = 2429) were drawn from the Association of American Medical Colleges (AAMC)'s National Sample Survey of Physicians (NSSP), collected in 2019 and 2022. Burnout was measured using a Maslach Burnout Inventory item, while COVID-19-affected aspects were reported in 2022.</p><p><strong>Principal findings: </strong>In 2022, 31.68% of respondents reported burnout once a week or higher. One in five physicians (19.43%) reported that COVID affected at least one aspect of their work status, while 67.77% reported that it affected at least one aspect of their practice. Cross-sectional analysis found that high burnout was reported by 30.41% of physicians whose work was not affected by COVID-19, compared to 37.00% (95% CI: 32.20-41.79, p = 0.015) among those who reported at least one affected aspect. Similarly, high burnout was reported by 27.19% of physicians with no COVID-affected practice aspects and 33.83% (95% CI: 31.42-36.24, p = 0.002) of those with at least one affected aspect. Longitudinal analysis revealed a 0.07 (p = 0.001) increase in burnout frequency on the 0-4 scale from 2019 to 2022. Increased work hours (b = 0.01, p < 0.001) and transitioning from other specialties into primary care specialties (b = 0.15, p < 0.001) significantly contributed to increased burnout.</p><p><strong>Conclusions: </strong>These findings quantify the detrimental effects of COVID-19-related work and practice changes on burnout and provide insights for policymakers and healthcare organizations to develop targeted strategies to mitigate the negative impacts of future public health crises.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70003"},"PeriodicalIF":3.2,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Criticism to Comfort: The Relational Benefits of Long-Term Care Insurance.","authors":"Xianhua Zai","doi":"10.1111/1475-6773.70026","DOIUrl":"https://doi.org/10.1111/1475-6773.70026","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study is to examine whether potentially eligible individuals with Partnership Long-Term Care Insurance (PLTCI) program experience stronger social networks and improved interpersonal relationships compared to those without coverage.</p><p><strong>Study setting and design: </strong>Our analysis utilizes data from the Health and Retirement Study (HRS), a longitudinal survey of U.S. adults aged 50 and older, incorporating responses from the Leave-Behind Questionnaire administered biennially from 2004 to 2018. We merge these data with a dataset tracking state-level implementation of the PLTCI program, enabling us to construct a binary indicator of policy exposure based on respondents' state of residence. Using ordinary least squares (OLS) regression with two-way fixed effects, we estimate the effect of the PLTCI program on the relational outcomes of aging individuals.</p><p><strong>Data sources and analytic sample: </strong>The analytic sample includes HRS respondents potentially eligible for the PLTCI program at the time of its implementation, focusing on respondents and their spouse no more than 65 years without physical limitations per Activities of Daily Living (ADL) criteria. Depending on data availability, the sample size ranges from approximately 13,000 to 17,000 participants.</p><p><strong>Principal findings: </strong>The PLTCI program improved perceived relationships with children and spouses. Older adults reported less frequent criticism (4.3% decrease with children, p = 0.04, 95% CI: 0.3%-8.3%; 3.4% with spouse, p = 0.04), feeling let down (3.9% decrease with children, p = 0.01; 3.8% with spouse, p = 0.009), or being annoyed (3.5% decrease with children, p = 0.03). They also felt more comfortable opening up about worries (2.1% increase with children) and relying on close family members during serious problems (3.0% increase with children, p = 0.01). These effects were strongest among individuals aged 55 and older compared to younger individuals, non-Hispanic White respondents compared to non-Hispanic Black respondents, and those with higher household wealth compared to those with lower household wealth.</p><p><strong>Conclusions: </strong>Beyond financial security, the PLTCI program enhances older adults' social and emotional well-being by improving close relationships. These findings highlight the need to consider both economic and relational outcomes when evaluating long-term care policies.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70026"},"PeriodicalIF":3.2,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Survival Impact and Cost-Effectiveness of Multi-Gene Panel Sequencing in Metastatic Colorectal Cancer With Super Learning Approaches.","authors":"Emanuel Krebs, Deirdre Weymann, Howard J Lim, Stephen Yip, Dean A Regier","doi":"10.1111/1475-6773.70009","DOIUrl":"https://doi.org/10.1111/1475-6773.70009","url":null,"abstract":"<p><strong>Objective: </strong>To determine the effectiveness and cost-effectiveness of multi-gene panel sequencing compared to single-gene KRAS testing for metastatic colorectal cancer (mCRC).</p><p><strong>Study setting and design: </strong>British Columbia, Canada (BC) is a provincial single-payer public healthcare system, and it was the first province to publicly reimburse multi-gene sequencing for mCRC. Panels expand treatment de-escalation by expanding RAS testing for more precise targeting of anti-EGFR therapies. Reimbursement of panels remains unequal across healthcare systems given uncertain clinical and economic impacts. Our quasi-experimental study design followed the target trial emulation approach, emulating random treatment assignment with two different methods to examine the sensitivity of estimates: inverse probability of treatment weighting estimated with super learning (SL-IPTW) and 1:1 genetic algorithm-based matching, a machine learning approach. We then estimated mean three-year survival time and costs (public healthcare payer perspective; 2021CAD) and calculated the incremental net monetary benefit (INMB) for life-years gained (LYG) at $50,000/LYG using weighted linear regression and nonparametric bootstrapping, also accounting for inverse probability of censoring weights. Our sensitivity analysis estimated LYG using targeted minimum-based loss estimation (TMLE), a doubly robust approach that also uses super learning.</p><p><strong>Data sources and analytical sample: </strong>Patient-level linked administrative health databases capturing cancer and non-cancer care for all BC adults with a metastatic colorectal cancer between 2016 and 2019.</p><p><strong>Principal findings: </strong>Our study included 892 patients (84.3%) receiving multi-gene panels and 166 (15.7%) receiving single-gene testing. INMB estimates were similar for SL-IPTW ($20,397; 95% CI: $9317, $34,862) and matching ($19,569; 95% CI: $8509, $31,447), with 99.3% and 98.8% probabilities, respectively, of panels being cost-effective. We found statistically significant survival benefits with LYG of 0.31 (SL-IPTW; 95% CI: 0.04, 0.54), 0.25 (matching; 95% CI: 0.03, 0.47) and 0.19 (TMLE; 95% CI: 0.02, 0.37).</p><p><strong>Conclusions: </strong>Survival impacts were robust to super learning approaches. Real-world evidence demonstrates that reimbursing multi-gene sequencing for more precise targeting of mCRC treatments provides value for healthcare systems and clinically important benefits to patients.</p>","PeriodicalId":55065,"journal":{"name":"Health Services Research","volume":" ","pages":"e70009"},"PeriodicalIF":3.2,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}