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Identification and profiling of microRNAs responsive to cadmium toxicity in hepatopancreas of the freshwater crab Sinopotamon henanense 河蟹肝胰腺对镉毒性反应的微小RNA的鉴定和谱分析
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-11-04 DOI: 10.1186/s41065-019-0110-z
P. Xu, Huiqin Guo, Huihui Wang, Yuxin Xie, Shao-Chin Lee, Ming Liu, Jian Zheng, Xi-lian Mao, Huan Wang, Fatao Liu, C. Wan, Shengying Qin, Yun Liu, Mei-rong Zhao, Lan Wang
{"title":"Identification and profiling of microRNAs responsive to cadmium toxicity in hepatopancreas of the freshwater crab Sinopotamon henanense","authors":"P. Xu, Huiqin Guo, Huihui Wang, Yuxin Xie, Shao-Chin Lee, Ming Liu, Jian Zheng, Xi-lian Mao, Huan Wang, Fatao Liu, C. Wan, Shengying Qin, Yun Liu, Mei-rong Zhao, Lan Wang","doi":"10.1186/s41065-019-0110-z","DOIUrl":"https://doi.org/10.1186/s41065-019-0110-z","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0110-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41756485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Identification of RUNX2 variants associated with cleidocranial dysplasia 与裂颅发育不良相关的RUNX2变异体的鉴定
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-09-16 DOI: 10.1186/s41065-019-0107-7
Xueren Gao, Kunxia Li, Yanjie Fan, Yu Sun, Xiaomei Luo, Lili Wang, Huili Liu, Z. Gong, Jianguo Wang, Yu Wang, Xuefan Gu, Yongguo Yu
{"title":"Identification of RUNX2 variants associated with cleidocranial dysplasia","authors":"Xueren Gao, Kunxia Li, Yanjie Fan, Yu Sun, Xiaomei Luo, Lili Wang, Huili Liu, Z. Gong, Jianguo Wang, Yu Wang, Xuefan Gu, Yongguo Yu","doi":"10.1186/s41065-019-0107-7","DOIUrl":"https://doi.org/10.1186/s41065-019-0107-7","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0107-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45082264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
bicoid RNA localization requires the trans-Golgi network 双曲面RNA的定位需要反式高尔基网络
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-09-10 DOI: 10.1186/s41065-019-0106-8
Xiaoli Cai, Khalid Fahmy, S. Baumgartner
{"title":"bicoid RNA localization requires the trans-Golgi network","authors":"Xiaoli Cai, Khalid Fahmy, S. Baumgartner","doi":"10.1186/s41065-019-0106-8","DOIUrl":"https://doi.org/10.1186/s41065-019-0106-8","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0106-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46632051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Detect accessible chromatin using ATAC-sequencing, from principle to applications 检测可利用的染色质使用atac测序，从原理到应用
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-08-15 DOI: 10.1186/s41065-019-0105-9
Yuanyuan Sun, Nan Miao, Tao Sun
{"title":"Detect accessible chromatin using ATAC-sequencing, from principle to applications","authors":"Yuanyuan Sun, Nan Miao, Tao Sun","doi":"10.1186/s41065-019-0105-9","DOIUrl":"https://doi.org/10.1186/s41065-019-0105-9","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0105-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48358122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
Hereditary spastic paraplegia associated with a rare IFIH1 mutation: a case report and literature review 遗传性痉挛性截瘫伴罕见IFIH1突变1例报告及文献复习
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-08-13 DOI: 10.1186/s41065-019-0104-x
Nan Liu, Jiajun Chen, Chuan Xu, Tianji Shi, Jia Li
{"title":"Hereditary spastic paraplegia associated with a rare IFIH1 mutation: a case report and literature review","authors":"Nan Liu, Jiajun Chen, Chuan Xu, Tianji Shi, Jia Li","doi":"10.1186/s41065-019-0104-x","DOIUrl":"https://doi.org/10.1186/s41065-019-0104-x","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0104-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46711856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
ABCG2 gene polymorphism rs2231142 is associated with gout comorbidities but not allopurinol response in primary gout patients of a Chinese Han male population ABCG2基因多态性rs2231142与中国汉族男性原发性痛风患者的痛风合并症相关，但与别嘌呤醇反应无关
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-07-24 DOI: 10.1186/s41065-019-0103-y
Keke Zhang, Changgui Li
{"title":"ABCG2 gene polymorphism rs2231142 is associated with gout comorbidities but not allopurinol response in primary gout patients of a Chinese Han male population","authors":"Keke Zhang, Changgui Li","doi":"10.1186/s41065-019-0103-y","DOIUrl":"https://doi.org/10.1186/s41065-019-0103-y","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0103-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49559888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Expression analysis of Argonaute genes in maize (Zea mays L.) in response to abiotic stress 玉米Argonaute基因在非生物胁迫下的表达分析
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-07-24 DOI: 10.1186/s41065-019-0102-z
Lihong Zhai, F. Teng, Kangpeng Zheng, Juan Xiao, W. Deng, Wei Sun
{"title":"Expression analysis of Argonaute genes in maize (Zea mays L.) in response to abiotic stress","authors":"Lihong Zhai, F. Teng, Kangpeng Zheng, Juan Xiao, W. Deng, Wei Sun","doi":"10.1186/s41065-019-0102-z","DOIUrl":"https://doi.org/10.1186/s41065-019-0102-z","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0102-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49233086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses 通过综合生物信息学分析综合鉴定阿尔茨海默病的关键基因和途径
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-07-16 DOI: 10.1186/s41065-019-0101-0
Tingting Yan, F. Ding, Yan Zhao
{"title":"Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses","authors":"Tingting Yan, F. Ding, Yan Zhao","doi":"10.1186/s41065-019-0101-0","DOIUrl":"https://doi.org/10.1186/s41065-019-0101-0","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0101-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46236670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
A co-expression network for differentially expressed genes in bladder cancer and a risk score model for predicting survival 膀胱癌症差异表达基因的共表达网络和预测生存率的风险评分模型
IF 2.7 3区 生物学
Hereditas Pub Date : 2019-07-09 DOI: 10.1186/s41065-019-0100-1
Zihao Chen, Guojun Liu, A. Hossain, I. Danilova, M. Bolkov, Guoqing Liu, I. Tuzankina, W. Tan
{"title":"A co-expression network for differentially expressed genes in bladder cancer and a risk score model for predicting survival","authors":"Zihao Chen, Guojun Liu, A. Hossain, I. Danilova, M. Bolkov, Guoqing Liu, I. Tuzankina, W. Tan","doi":"10.1186/s41065-019-0100-1","DOIUrl":"https://doi.org/10.1186/s41065-019-0100-1","url":null,"abstract":"","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s41065-019-0100-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42113314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses 表观基因组-转录组学综合分析揭示了纤维素囊虫关键寄生基因的DNA甲基化调控
IF 2.7 3区 生物学
Hereditas Pub Date : 2018-06-21 DOI: 10.1101/353417
Xinrui Wang, Weiyi Song, G. Ji, Yining Song, Xiaolei Liu, Xue-nong Luo, Mingyuan Liu, Shumin Sun
{"title":"Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses","authors":"Xinrui Wang, Weiyi Song, G. Ji, Yining Song, Xiaolei Liu, Xue-nong Luo, Mingyuan Liu, Shumin Sun","doi":"10.1101/353417","DOIUrl":"https://doi.org/10.1101/353417","url":null,"abstract":"Background The life cycle of  Taenia solium  is characterized by different stages of development, requiring various kinds of hosts that can appropriately harbor the eggs (proglottids), the oncospheres, the larvae and the adults. Similar to other metazoan pathogens, T. solium undergoes transcriptional and developmental regulation via epigenetics during its complex lifecycle and host interactions. Result In the present study, we integrated whole-genome bisulfite sequencing and RNA-seq technologies to characterize the genome-wide DNA methylation and its effect on transcription of Cysticercus cellulosae of T. solium . We confirm that the T. solium genome in the cysticercus stage is epigenetically modified by DNA methylation in a pattern similar to that of other invertebrate genomes, i.e., sparsely or moderately methylated. We also observed an enrichment of non-CpG methylation in defined genetic elements of the T. solium genome. Furthermore, an integrative analysis of both the transcriptome and the DNA methylome indicated a strong correlation between these two datasets, suggesting that gene expression might be tightly regulated by DNA methylation. Importantly, our data suggested that DNA methylation might play an important role in repressing key parasitism-related genes, including genes encoding excretion-secretion proteins, thereby raising the possibility of targeting DNA methylation processes as a useful strategy in therapeutics of cysticercosis.","PeriodicalId":55057,"journal":{"name":"Hereditas","volume":"158 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2018-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46106937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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