Journal of Biological Systems最新文献_第3页

Effects of Anti-Predator Behavior on a Stochastic Predator-Prey System 反捕食者行为对随机捕食者-猎物系统的影响

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-23 DOI: 10.1142/s0218339024500219

Yanan Sun, Youming Lei, Xinzhi Liu

引用次数: 0

The Impact of Stochastic Environment on Psychological Health Dynamics 随机环境对心理健康动态的影响

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-23 DOI: 10.1142/s0218339024500207

Feng Rao, Anqi Wang, Zhanyu Wang

引用次数: 0

ENDEAVORING THE ROLE OF OBESITY IN EXTRACELLULAR MATRIX DEGRADATION LEADING TO METASTASIS 研究肥胖在细胞外基质降解导致转移中的作用

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-06 DOI: 10.1142/s0218339024500153

Ani Jain, Parimita Roy

{"title":"ENDEAVORING THE ROLE OF OBESITY IN EXTRACELLULAR MATRIX DEGRADATION LEADING TO METASTASIS","authors":"Ani Jain, Parimita Roy","doi":"10.1142/s0218339024500153","DOIUrl":"https://doi.org/10.1142/s0218339024500153","url":null,"abstract":"One of the significant causes of death globally is cancer ( http://www.who.org/ ). Another critical problem is obesity, which is associated with an increased cancer threat. This work provides insight into how obesity contributes to cancer progression and metastasis. We developed a diffusive obesity-cancer model consisting of cancer cells, normal cells, fat cells, macrophages, and an extracellular matrix (ECM) for this aim. We have directed the formed model’s global existence and non-negativity. Equilibrium points for the related ODE are calculated, and its existence and stability study is also done. We present a traveling wave analysis of the obesity-cancer model and have calculated the minimum wave speed. Using a combination of analytic and numerical results of traveling waves, we conjecture that the minimal wave speed depends on fat cells’ diffusive rate and haptotaxis coefficient. We followed the theory of the Partial Rank Correlation Coefficient (PRCC) to carry out a global sensitivity analysis to evaluate the most sensitive parameters reliable for cancer progression. We delivered a comprehensive numerical analysis of our deterministic and diffusive models (in 1D and 2D) and analogized the result. Numerical simulation of corresponding spatially explicit systems conveys complex spatio-temporal dynamics, resulting in the appearance of patterns. It also discloses that cancer spread increases with increased haptotaxis coefficient and growth rate of obese cells. Our simulation confirms that the degradation of the ECM increases cancer spread and density.","PeriodicalId":54872,"journal":{"name":"Journal of Biological Systems","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139965173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OPTIMAL CONTROL ON FRACTIONAL ENZYME KINETICS WITH INHIBITORS 带抑制剂的部分酶动力学优化控制

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-01 DOI: 10.1142/s0218339024500189

M. Vellappandi, J. Kokila, V. Govindaraj

引用次数: 0

OPTIMAL CONTROL ON FRACTIONAL ENZYME KINETICS WITH INHIBITORS 带抑制剂的部分酶动力学优化控制

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-01 DOI: 10.1142/s0218339024500189

M. Vellappandi, J. Kokila, V. Govindaraj

引用次数: 0

MATHEMATICAL MODEL FOR SYSTEM DYNAMICS OF (Ca2+) AND DOPAMINE IN A FIBROBLAST CELL 纤维泡沫细胞中（Ca2+）和多巴胺的系统动力学数学模型

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-01 DOI: 10.1142/s0218339024500177

Ankit Kothiya, N. Adlakha

{"title":"MATHEMATICAL MODEL FOR SYSTEM DYNAMICS OF (Ca2+) AND DOPAMINE IN A FIBROBLAST CELL","authors":"Ankit Kothiya, N. Adlakha","doi":"10.1142/s0218339024500177","DOIUrl":"https://doi.org/10.1142/s0218339024500177","url":null,"abstract":"Fibroblasts significantly affect wound healing, cancer progression and development. Disturbances in the calcium [Formula: see text] and dopamine [Formula: see text] dynamics leads to fibrotic disorders like cancer and fibrosis. Calcium signaling is required for [Formula: see text] concentrations in fibroblasts. Alteration in the many processes of [Formula: see text] kinetics can disturb [Formula: see text] regulation in fibroblast cells. No model has been reported till date for the study of spatiotemporal relationships of [Formula: see text] with calcium signaling in fibroblasts. A model is provided here to study the dynamic relationship of [Formula: see text] regulation with calcium signaling in a fibroblast cell. Finite element and Crank–Nicholson techniques are employed for numerical simulation. The numerical results provide insights into the buffer, source influx, and diffusion effects on the spatiotemporal dynamics of [Formula: see text] and [Formula: see text] in a fibroblast. Disturbances in the constitutive processes in the system dynamics of [Formula: see text] and [Formula: see text] can cause fibrotic diseases such as fibrosis and cancer in various organs.","PeriodicalId":54872,"journal":{"name":"Journal of Biological Systems","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139825227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MATHEMATICAL MODEL FOR SYSTEM DYNAMICS OF (Ca2+) AND DOPAMINE IN A FIBROBLAST CELL 纤维泡沫细胞中（Ca2+）和多巴胺的系统动力学数学模型

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-02-01 DOI: 10.1142/s0218339024500177

Ankit Kothiya, N. Adlakha

{"title":"MATHEMATICAL MODEL FOR SYSTEM DYNAMICS OF (Ca2+) AND DOPAMINE IN A FIBROBLAST CELL","authors":"Ankit Kothiya, N. Adlakha","doi":"10.1142/s0218339024500177","DOIUrl":"https://doi.org/10.1142/s0218339024500177","url":null,"abstract":"Fibroblasts significantly affect wound healing, cancer progression and development. Disturbances in the calcium [Formula: see text] and dopamine [Formula: see text] dynamics leads to fibrotic disorders like cancer and fibrosis. Calcium signaling is required for [Formula: see text] concentrations in fibroblasts. Alteration in the many processes of [Formula: see text] kinetics can disturb [Formula: see text] regulation in fibroblast cells. No model has been reported till date for the study of spatiotemporal relationships of [Formula: see text] with calcium signaling in fibroblasts. A model is provided here to study the dynamic relationship of [Formula: see text] regulation with calcium signaling in a fibroblast cell. Finite element and Crank–Nicholson techniques are employed for numerical simulation. The numerical results provide insights into the buffer, source influx, and diffusion effects on the spatiotemporal dynamics of [Formula: see text] and [Formula: see text] in a fibroblast. Disturbances in the constitutive processes in the system dynamics of [Formula: see text] and [Formula: see text] can cause fibrotic diseases such as fibrosis and cancer in various organs.","PeriodicalId":54872,"journal":{"name":"Journal of Biological Systems","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139884897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MODELING THE IMPACT OF RAINFALL AND TEMPERATURE ON STERILE INSECT CONTROL STRATEGIES IN A TROPICAL ENVIRONMENT 模拟降雨和温度对热带环境中昆虫不育控制策略的影响

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2024-01-05 DOI: 10.1142/s0218339024500128

Y. DUMONT, M. DUPREZ

{"title":"MODELING THE IMPACT OF RAINFALL AND TEMPERATURE ON STERILE INSECT CONTROL STRATEGIES IN A TROPICAL ENVIRONMENT","authors":"Y. DUMONT, M. DUPREZ","doi":"10.1142/s0218339024500128","DOIUrl":"https://doi.org/10.1142/s0218339024500128","url":null,"abstract":"The sterile insect technique (SIT) is a biological control technique that can be used either to eliminate or decay a wild mosquito population under a given threshold to reduce the nuisance or the epidemiological risk. In this work, we propose a model using a differential system that takes into account the variations of rainfall and temperature over time and study their impacts on sterile males’ releases strategies. Our model is as simple as possible to avoid complexity while being able to capture the temporal variations of an Aedes albopictus mosquito population in a domain treated by SIT, located in Réunion island. The main objective is to determine what period of the year is the most suitable to start a SIT control to minimize the duration of massive releases and the number of sterile males to release, either to reduce the mosquito nuisance, or to reduce the epidemiological risk. Since sterilization is not <math altimg=\"eq-00001.gif\" display=\"inline\" overflow=\"scroll\"><mn>1</mn><mn>0</mn><mn>0</mn><mi>%</mi></math> efficient, we also study the impact of different levels of residual fertility within the released sterile males population. Our study shows that rainfall plays a major role in the dynamics of the mosquito and the SIT control, that the best period to start a massive SIT treatment lasts from July to December, that residual fertility has to be as small as possible, at least for nuisance reduction. Indeed, when the main objective is to reduce the epidemiological risk, we show that residual fertility is not necessarily an issue. Increasing the size of the releases is not always interesting. We also highlight the importance of combining SIT with mechanical control, i.e., the removal of breeding sites, in particular when the initial mosquito population is large. Last but not least our study shows the usefulness of the modeling approach to derive various simulations to anticipate issues and demand in terms of sterile insects’ production.","PeriodicalId":54872,"journal":{"name":"Journal of Biological Systems","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140150174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of hunting cooperation and fear effect in a generalist predator-prey model 综合捕食者-猎物模型中狩猎合作和恐惧效应的影响

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2023-11-28 DOI: 10.1142/s021833902340003x

Anuj Kumar Umrao, Prashant K. Srivastava

引用次数: 0

BIFURCATION ANALYSIS AND CHAOS CONTROL OF DISCRETE PREDATOR–PREY MODEL WITH ADDITIVE ALLEE EFFECT 具有加法等位基因效应的离散捕食者-猎物模型的分岔分析与混沌控制

IF 1.6 4区数学

Journal of Biological Systems Pub Date : 2023-11-21 DOI: 10.1142/s0218339023500493

Hanghang Li, Xinli Hu

引用次数: 0