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Journal of Dynamical and Control Systems最新文献

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Finite-Time Stabilization and Impulse Control of Heat Equation with Dynamic Boundary Conditions 具有动态边界条件的热方程的有限时间镇定与脉冲控制
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-12-20 DOI: 10.1007/s10883-023-09646-0
Salah-Eddine Chorfi, G. E. Guermai, L. Maniar, W. Zouhair
{"title":"Finite-Time Stabilization and Impulse Control of Heat Equation with Dynamic Boundary Conditions","authors":"Salah-Eddine Chorfi, G. E. Guermai, L. Maniar, W. Zouhair","doi":"10.1007/s10883-023-09646-0","DOIUrl":"https://doi.org/10.1007/s10883-023-09646-0","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44007779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Stabilization of Series Heat Equations with One Boundary Control 单边界控制下系列热方程的稳定性
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-12-19 DOI: 10.1007/s10883-022-09618-w
Lina Pan, Jun‐min Wang
{"title":"Stabilization of Series Heat Equations with One Boundary Control","authors":"Lina Pan, Jun‐min Wang","doi":"10.1007/s10883-022-09618-w","DOIUrl":"https://doi.org/10.1007/s10883-022-09618-w","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":"29 1","pages":"969 - 987"},"PeriodicalIF":0.9,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47043384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Conjugacy of Vector Fields via Tame Hyperbolic Structure 通过驯服双曲结构的向量场的全局共轭
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-12-17 DOI: 10.1007/s10883-022-09622-0
Souad Meftahi, A. Lansari, Mohammed Benalili
{"title":"Global Conjugacy of Vector Fields via Tame Hyperbolic Structure","authors":"Souad Meftahi, A. Lansari, Mohammed Benalili","doi":"10.1007/s10883-022-09622-0","DOIUrl":"https://doi.org/10.1007/s10883-022-09622-0","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":"29 1","pages":"945 - 967"},"PeriodicalIF":0.9,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48467587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance Output Tracking for an ODE Cascaded with Schrödinger Equation Subject to Disturbances 受扰动的Schrödinger方程级联ODE的性能输出跟踪
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-12-15 DOI: 10.1007/s10883-022-09631-z
Yi-Jing Li, Jun-Jun Liu
{"title":"Performance Output Tracking for an ODE Cascaded with Schrödinger Equation Subject to Disturbances","authors":"Yi-Jing Li, Jun-Jun Liu","doi":"10.1007/s10883-022-09631-z","DOIUrl":"https://doi.org/10.1007/s10883-022-09631-z","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":"29 1","pages":"901 - 917"},"PeriodicalIF":0.9,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42376858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classification of Initial Energy to a Pseudo-parabolic Equation with p(x)-Laplacian 带p(x)-拉普拉斯算子的伪抛物方程初始能量的分类
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-12-14 DOI: 10.1007/s10883-022-09629-7
Xizheng Sun, Bingchen Liu
{"title":"Classification of Initial Energy to a Pseudo-parabolic Equation with p(x)-Laplacian","authors":"Xizheng Sun, Bingchen Liu","doi":"10.1007/s10883-022-09629-7","DOIUrl":"https://doi.org/10.1007/s10883-022-09629-7","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":"29 1","pages":"873 - 899"},"PeriodicalIF":0.9,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41840898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Null Controllability of Networks Systems 网络系统的零可控性
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-12-02 DOI: 10.1007/s10883-022-09623-z
M. El Azzouzi, Abdellah Lourini, M. Laabissi
{"title":"Null Controllability of Networks Systems","authors":"M. El Azzouzi, Abdellah Lourini, M. Laabissi","doi":"10.1007/s10883-022-09623-z","DOIUrl":"https://doi.org/10.1007/s10883-022-09623-z","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":"29 1","pages":"855 - 872"},"PeriodicalIF":0.9,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47049663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An Optimal Treatment Strategy for a Leukemia Immune Model Governed by Reaction-Diffusion Equations 反应扩散方程控制的白血病免疫模型的最优治疗策略
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-11-24 DOI: 10.1007/s10883-022-09621-1
Huili Xiang, Min Zhou, Xuanfeng Liu
{"title":"An Optimal Treatment Strategy for a Leukemia Immune Model Governed by Reaction-Diffusion Equations","authors":"Huili Xiang, Min Zhou, Xuanfeng Liu","doi":"10.1007/s10883-022-09621-1","DOIUrl":"https://doi.org/10.1007/s10883-022-09621-1","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43977896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shadowing Property of 1-dimensional Subsystems for Suspension of $mathbb {Z}^{k}$-actions $mathbb｛Z｝^｛k｝$作用暂停的一维子系统的阴影性质
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-11-23 DOI: 10.1007/s10883-022-09625-x
L. Wang, Jinlian Zhang
{"title":"Shadowing Property of 1-dimensional Subsystems for Suspension of $mathbb {Z}^{k}$-actions","authors":"L. Wang, Jinlian Zhang","doi":"10.1007/s10883-022-09625-x","DOIUrl":"https://doi.org/10.1007/s10883-022-09625-x","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47748069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chimeric antigen receptor clustering via cysteines enhances T-cell efficacy against tumor. 通过半胱氨酸聚类的嵌合抗原受体可增强 T 细胞对肿瘤的疗效。
IF 5.8 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-11-01 Epub Date: 2022-04-19 DOI: 10.1007/s00262-022-03195-4
Yuedi Wang, Yiyuan Gao, Congyi Niu, Bo Wang, Shushu Zhao, Gils Roex, Jiawen Qian, Jingbo Qie, Lin Chen, Chenhe Yi, Sébastien Anguille, Jie Liu, Feifei Luo, Yiwei Chu
{"title":"Chimeric antigen receptor clustering via cysteines enhances T-cell efficacy against tumor.","authors":"Yuedi Wang, Yiyuan Gao, Congyi Niu, Bo Wang, Shushu Zhao, Gils Roex, Jiawen Qian, Jingbo Qie, Lin Chen, Chenhe Yi, Sébastien Anguille, Jie Liu, Feifei Luo, Yiwei Chu","doi":"10.1007/s00262-022-03195-4","DOIUrl":"10.1007/s00262-022-03195-4","url":null,"abstract":"<p><p>Chimeric antigen receptor (CAR) T-cell therapy achieves great success for hematological malignancies. However, clinical trials have revealed some limitations in both improving the efficacy and reducing the relapse, which calls for innovative strategies to engineer more powerful CAR-T cells. Promoting the formation of CAR clusters provides an alternative approach and potentially improves current CAR T-cell therapy against cancers. Here, we generated CAR<sub>Cys</sub>-T cells using a 4-1BB-derived hinge region including 11 cysteines residues. The cysteines in the hinge were found to facilitate CAR<sub>Cys</sub> clustering upon antigen stimulation and promote the antitumor activity of CAR-T cells. Compared with most conventionally used CAR-T cells with CD8α-derived hinge (CAR<sub>conv</sub>-T cells), CAR<sub>Cys</sub>-T cells exhibited larger diameter of CAR clusters and enhanced antigen-specific tumor lysis both in vitro and in vivo. In addition, the CAR<sub>Cys</sub>-mediated enhancement could be applied to HER2, CD19 as well as GPC3-targeted CAR-T cells. More importantly, CAR<sub>Cys</sub>-T cells showed potent antitumor efficacy in clinically relevant patient-derived primary tumor cells and organoids. Thus, the novel hinge containing 11 cysteines provides a promising strategy to facilitate CAR clustering and maximize anti-tumor activity of CAR-T cells, which emphasizes the importance of CAR clustering to improve CAR T-cell therapy in the clinic.</p>","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":"24 1","pages":"2801-2814"},"PeriodicalIF":5.8,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10992513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87749677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On Integral Conditions for the Existence of First Integrals for Analytic Deformations of Complex Saddle Singularities 复鞍奇异性解析变形第一积分存在的积分条件
IF 0.9 4区 数学
Journal of Dynamical and Control Systems Pub Date : 2022-10-21 DOI: 10.1007/s10883-022-09612-2
V. León, B. Scárdua
{"title":"On Integral Conditions for the Existence of First Integrals for Analytic Deformations of Complex Saddle Singularities","authors":"V. León, B. Scárdua","doi":"10.1007/s10883-022-09612-2","DOIUrl":"https://doi.org/10.1007/s10883-022-09612-2","url":null,"abstract":"","PeriodicalId":54847,"journal":{"name":"Journal of Dynamical and Control Systems","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42764249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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