Proceedings of the National Academy of Sciences, India. Section B最新文献

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Viral Vaccines in India: An Overview. 印度的病毒疫苗：综述。

Proceedings of the National Academy of Sciences, India. Section B Pub Date : 2012-01-01 Epub Date: 2012-01-17 DOI: 10.1007/s40011-011-0014-9

Kaushik Bharati, Sudhanshu Vrati

引用次数: 0

Influenza Virus: A Brief Overview. 流感病毒:概述。

Proceedings of the National Academy of Sciences, India. Section B Pub Date : 2012-01-01 Epub Date: 2012-01-18 DOI: 10.1007/s40011-011-0009-6

Tanushree Dangi, Amita Jain

{"title":"Influenza Virus: A Brief Overview.","authors":"Tanushree Dangi, Amita Jain","doi":"10.1007/s40011-011-0009-6","DOIUrl":"https://doi.org/10.1007/s40011-011-0009-6","url":null,"abstract":"Influenza is a major public health concern, infecting 5-15% of the global population annually. Influenza virus belongs to family Orthomyxoviridae, and has three types A, B and C. Infection by influenza virus A is most common and severe, generally found in humans. It spreads rapidly and affects human population across large geographical region within short period of time with varying degree of pathology from mild to severe. Wild aquatic birds and other animal species like birds, pigs, ferret, horses, seals, whales, mink, giant anteaters, cats and dogs are the reservoir for the influenza A virus. Influenza B and C viruses have very limited host range and appear predominantly in humans. Influenza virus gains pandemic potential through genetic reassortment called \"genetic shift\" with complete renewal of surface antigen and a small but gradual genetic change by mutations which make it to adapt efficiently in human population called \"genetic drift\". Although, the epidemiology related to influenza infection has been studied from several years but some facts associated to disease transmission has poorly understood. This article reviews the important aspects of virological, epidemiological and clinical features related to influenza virus for better understanding of disease transmission and its pathogenesis.","PeriodicalId":54564,"journal":{"name":"Proceedings of the National Academy of Sciences, India. Section B","volume":"82 1","pages":"111-121"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40011-011-0009-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37831389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Rapid and Real-time Detection of Human Viral Infections: Current Trends and Future Perspectives. 人类病毒感染的快速实时检测:当前趋势和未来展望。

Proceedings of the National Academy of Sciences, India. Section B Pub Date : 2012-01-01 Epub Date: 2012-01-18 DOI: 10.1007/s40011-011-0015-8

Manmohan Parida, Jyoti Shukla, Shashi Sharma, P V Lakshmana Rao

{"title":"Rapid and Real-time Detection of Human Viral Infections: Current Trends and Future Perspectives.","authors":"Manmohan Parida, Jyoti Shukla, Shashi Sharma, P V Lakshmana Rao","doi":"10.1007/s40011-011-0015-8","DOIUrl":"https://doi.org/10.1007/s40011-011-0015-8","url":null,"abstract":"The development of technologies with rapid and sensitive detection capabilities and increased throughput have become crucial for responding to greater number of threats posed by emerging and re-emerging viruses in the recent past. The conventional identification methods require time-consuming culturing, and/or detection of antibodies, which are not very sensitive and specific. The recent advances in molecular biology techniques in the field of genomics and proteomics greatly facilitate the rapid identification with more accuracy. The real-time assays viz; SYBR green I based real time RT-PCR and RT-LAMP have been developed for rapid detection as well as typing of some of the emerging arboviruses of biomedical importance viz; Dengue, Japanese Encephalitis, Chikungunya, West Nile, SARS and Swine Flu etc. Both these techniques are capable of detection and differentiation as well as quantifying viral load with higher sensitivity, rapidity and specificity. One of the most important advantages of RT-LAMP is its field applicability, without requirement of any sophisticated equipments. The establishment of these real time molecular assays will certainly facilitate the rapid detection of viruses with high degree of precision and accuracy in future.","PeriodicalId":54564,"journal":{"name":"Proceedings of the National Academy of Sciences, India. Section B","volume":"82 1","pages":"199-207"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40011-011-0015-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37783974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

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