Theory in Biosciences最新文献_第10页

Optimal harvesting and stability of a predator-prey model for fish populations with schooling behavior. 具有鱼群行为的捕食者-猎物模型的最优收获和稳定性。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-06-01 Epub Date: 2021-05-25 DOI: 10.1007/s12064-021-00347-5

Mohamed El Mahdi Hacini, Djammel Hammoudi, Salih Djilali, Soufiane Bentout

引用次数: 5

A reaction norm perspective on reproducibility. 从反应规范角度看可重复性。

IF 1.3 4区生物学

Theory in Biosciences Pub Date : 2021-06-01 Epub Date: 2021-03-25 DOI: 10.1007/s12064-021-00340-y

Bernhard Voelkl, Hanno Würbel

{"title":"A reaction norm perspective on reproducibility.","authors":"Bernhard Voelkl, Hanno Würbel","doi":"10.1007/s12064-021-00340-y","DOIUrl":"10.1007/s12064-021-00340-y","url":null,"abstract":"Reproducibility in biomedical research, and more specifically in preclinical animal research, has been seriously questioned. Several cases of spectacular failures to replicate findings published in the primary scientific literature have led to a perceived reproducibility crisis. Diverse threats to reproducibility have been proposed, including lack of scientific rigour, low statistical power, publication bias, analytical flexibility and fraud. An important aspect that is generally overlooked is the lack of external validity caused by rigorous standardization of both the animals and the environment. Here, we argue that a reaction norm approach to phenotypic variation, acknowledging gene-by-environment interactions, can help us seeing reproducibility of animal experiments in a new light. We illustrate how dominating environmental effects can affect inference and effect size estimates of studies and how elimination of dominant factors through standardization affects the nature of the expected phenotype variation through the reaction norms of small effect. Finally, we discuss the consequences of reaction norms of small effect for statistical analysis, specifically for random effect latent variable models and the random lab model.","PeriodicalId":54428,"journal":{"name":"Theory in Biosciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25531423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mathematical computations on epidemiology: a case study of the novel coronavirus (SARS-CoV-2). 流行病学的数学计算：新型冠状病毒（SARS-CoV-2）案例研究。

IF 1.3 4区生物学

Theory in Biosciences Pub Date : 2021-06-01 Epub Date: 2021-03-07 DOI: 10.1007/s12064-021-00339-5

Saikat Batabyal, Arthita Batabyal

{"title":"Mathematical computations on epidemiology: a case study of the novel coronavirus (SARS-CoV-2).","authors":"Saikat Batabyal, Arthita Batabyal","doi":"10.1007/s12064-021-00339-5","DOIUrl":"10.1007/s12064-021-00339-5","url":null,"abstract":"The outbreak of coronavirus COVID-19 is spreading at an unprecedented rate to the human populations and taking several thousands of life all over the world. Scientists are trying to map the pattern of the transmission of coronavirus (SARS-CoV-2). Many countries are in the phase of lockdown in the globe. In this paper we predict about the effect of coronavirus COVID-19 and give a sneak peak when it will reduce the transmission rate in the world via mathematical modelling. In this research work our study is based on extensions of the well-known susceptible-exposed-infected-recovered (SEIR) family of compartmental models and later we observe the new model changes into (SEIR) without changing its physical meanings. The stability analysis of the coronavirus depends on changing of its basic reproductive ratio. The progress rate of the virus in the critically infected cases and the recovery rate have major roles to control this epidemic. The impact of social distancing, lockdown of the country, self-isolation, home quarantine and the wariness of global public health system have significant influence on the parameters of the model system that can alter the effect of recovery rates, mortality rates and active contaminated cases with the progression of time in the real world. The prognostic ability of mathematical model is circumscribed as of the accuracy of the available data and its application to the problem.","PeriodicalId":54428,"journal":{"name":"Theory in Biosciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25455706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the historical roots of creationism and intelligent design: German Allmacht and Darwinian evolution in context. 论神创论与智能设计论的历史根源:语境中的德国万物论与达尔文进化论。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-06-01 Epub Date: 2021-03-24 DOI: 10.1007/s12064-021-00341-x

Elizabeth Watts, Ulrich Kutschera

引用次数: 1

Modelling and optimal control for Chikungunya disease. 基孔肯雅病的建模和最优控制。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-02-01 Epub Date: 2020-10-31 DOI: 10.1007/s12064-020-00324-4

Miled El Hajji

引用次数: 13

"Cladus" and clade: a taxonomic odyssey. “进化纲”和进化纲:一个分类学的奥德赛。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-02-01 Epub Date: 2020-10-23 DOI: 10.1007/s12064-020-00326-2

P Tassy, M S Fischer

{"title":"\"Cladus\" and clade: a taxonomic odyssey.","authors":"P Tassy, M S Fischer","doi":"10.1007/s12064-020-00326-2","DOIUrl":"https://doi.org/10.1007/s12064-020-00326-2","url":null,"abstract":"The fate of \"clade,\" both as concept and word, is reconstructed here beginning with its first appearance in 1866 as \"Cladus,\" in Haeckel's Generelle Morphologie, continuing up to the present. Although central to phylogenetics, the concept of clade is paradoxical since it has been ambiguously understood or even misunderstood by its own promoters. Writings by Ernst Haeckel, Lucien Cuénot, and Julian Huxley, the three authors who discussed the notion of clade at length, are analyzed here in detail as a means of exploring this paradox. First conceived as a rank for a higher-level category, and later as a taxon, the clade is understood today in connection with Hennig's definition of a monophyletic group rather than through Huxley's successful but somehow ambiguous formalization. The inability of these authors to formulate a clear-cut exposition of the concept is considered here within three contexts: firstly, the burden of pre-Darwinian classifications based on similarity; secondly, the underestimation of Darwin's description of a genealogical group; and thirdly, the predominance of thinking in process (vs thinking in pattern), which was the basis of evolutionary systematics in the mid-twentieth century.","PeriodicalId":54428,"journal":{"name":"Theory in Biosciences","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12064-020-00326-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38522349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypothesis: nucleoid-associated proteins segregate with a parental DNA strand to generate coherent phenotypic diversity. 假设:核相关蛋白与亲本DNA链分离产生一致的表型多样性。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-02-01 Epub Date: 2020-10-23 DOI: 10.1007/s12064-020-00323-5

Yoan Konto-Ghiorghi, Vic Norris

引用次数: 2

Equivalence classes of circular codes induced by permutation groups. 由置换群诱导的圆码的等价类。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-02-01 DOI: 10.1007/s12064-020-00337-z

Fariba Fayazi, Elena Fimmel, Lutz Strüngmann

{"title":"Equivalence classes of circular codes induced by permutation groups.","authors":"Fariba Fayazi, Elena Fimmel, Lutz Strüngmann","doi":"10.1007/s12064-020-00337-z","DOIUrl":"https://doi.org/10.1007/s12064-020-00337-z","url":null,"abstract":"In the 1950s, Crick proposed the concept of so-called comma-free codes as an answer to the frame-shift problem that biologists have encountered when studying the process of translating a sequence of nucleotide bases into a protein. A little later it turned out that this proposal unfortunately does not correspond to biological reality. However, in the mid-90s, a weaker version of comma-free codes, so-called circular codes, was discovered in nature in J Theor Biol 182:45-58, 1996. Circular codes allow to retrieve the reading frame during the translational process in the ribosome and surprisingly the circular code discovered in nature is even circular in all three possible reading-frames ([Formula: see text]-property). Moreover, it is maximal in the sense that it contains 20 codons and is self-complementary which means that it consists of pairs of codons and corresponding anticodons. In further investigations, it was found that there are exactly 216 codes that have the same strong properties as the originally found code from J Theor Biol 182:45-58. Using an algebraic approach, it was shown in J Math Biol, 2004 that the class of 216 maximal self-complementary [Formula: see text]-codes can be partitioned into 27 equally sized equivalence classes by the action of a transformation group [Formula: see text] which is isomorphic to the dihedral group. Here, we extend the above findings to circular codes over a finite alphabet of even cardinality [Formula: see text] for [Formula: see text]. We describe the corresponding group [Formula: see text] using matrices and we investigate what classes of circular codes are split into equally sized equivalence classes under the natural equivalence relation induced by [Formula: see text]. Surprisingly, this is not always the case. All results and constructions are illustrated by examples.","PeriodicalId":54428,"journal":{"name":"Theory in Biosciences","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12064-020-00337-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25318410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Mathematical modeling and analysis of anemia during pregnancy and postpartum. 妊娠及产后贫血的数学建模与分析。

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-02-01 Epub Date: 2021-02-15 DOI: 10.1007/s12064-020-00334-2

Auni Aslah Mat Daud, Cher Qing Toh, Salilah Saidun

引用次数: 2

Are topological explanations really free of mechanisms? 拓扑学解释真的不受机制的影响吗?

IF 1.1 4区生物学

Theory in Biosciences Pub Date : 2021-02-01 Epub Date: 2021-01-11 DOI: 10.1007/s12064-020-00336-0

Xin Zhang

引用次数: 0