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Current approaches to male anterior urethral reconstruction: what we do and why? 目前男性前尿道重建的方法:我们做什么,为什么?
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-12-01 DOI: 10.1016/j.jomh.2012.03.009
Jessica D. Lubahn MD , Steven J. Hudak MD , Allen F. Morey MD
{"title":"Current approaches to male anterior urethral reconstruction: what we do and why?","authors":"Jessica D. Lubahn MD ,&nbsp;Steven J. Hudak MD ,&nbsp;Allen F. Morey MD","doi":"10.1016/j.jomh.2012.03.009","DOIUrl":"10.1016/j.jomh.2012.03.009","url":null,"abstract":"<div><p>The management of male anterior urethral strictures<span><span> is complex and continues to evolve. Due to high success rates and low morbidity, open reconstruction has become the preferred primary treatment modality over repeated minimally invasive options. </span>Urethroplasty describes this diverse group of open reconstructive techniques applied to a heterogenous disease process. As controlled trials are scarce, a comparison of different techniques across varied circumstances is difficult. Furthermore, long-term success is also dependent upon patient comorbidities. Ultimately, accurate determination of the stricture length, location, and etiology is imperative for procedure selection. Therefore, we describe our approach and rationale behind the evaluation and treatment planning of patients with anterior urethral strictures, addressing current controversies and proposing future directions of research.</span></p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 4","pages":"Pages 207-215"},"PeriodicalIF":0.7,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of an informational pamphlet on distress and perceptions of supportive care for men with prostate cancer 对男性前列腺癌患者的痛苦和支持性护理认知的信息小册子的评价
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.03.011
Michèle Preyde PhD , Jane Hatton-Bauer RD , Craig Cunningham MSW , Dilip Panjwani MD
{"title":"Evaluation of an informational pamphlet on distress and perceptions of supportive care for men with prostate cancer","authors":"Michèle Preyde PhD ,&nbsp;Jane Hatton-Bauer RD ,&nbsp;Craig Cunningham MSW ,&nbsp;Dilip Panjwani MD","doi":"10.1016/j.jomh.2012.03.011","DOIUrl":"10.1016/j.jomh.2012.03.011","url":null,"abstract":"<div><h3>Background</h3><p><span>Many men with prostate cancer experience elevated levels of anxiety and distress which may interfere with their </span>quality of life<span>. Furthermore, there are challenges to providing supportive care in regional centers such as transportation difficulties. The purpose of this collaborative research project was to evaluate an informational pamphlet, and explore self-ratings of various emotional symptoms and optimal ways to provide psychosocial oncology to men with prostate cancer in a regional cancer centre.</span></p></div><div><h3>Methods</h3><p>Men with prostate cancer accessing medical treatment were invited to complete a survey about their emotional experiences and completed a quality of life measure. These men were given an informational pamphlet on distress, and were contacted approximately three weeks later to evaluate the pamphlet and the quality of life measure was re-administered. Qualitative comments on supportive care were elicited.</p></div><div><h3>Results</h3><p>Sixty-four men participated in the initial survey and 50 (78%) completed the evaluation of the pamphlet. The pamphlet was reported to be easy to read and contained useful information, though men would have preferred to receive this information at an earlier time. Distress and quality of life scores were similar to other samples of men with prostate cancer, and there were no statistically significant differences in quality of life scores for patients receiving radiation (<em>n</em> <!-->=<!--> <!-->44) compared to the other types (<em>n</em> <!-->=<!--> <!-->15) of medical treatment (F (1, 57)<!--> <!-->=<!--> <!-->0.610, <em>P</em> <!-->&lt;<!--> <!-->0.438). Of the emotional symptoms, “worry” and “anxiety” were rated as most problematic and “distress” as least problematic.</p></div><div><h3>Conclusions</h3><p>Overall, participants rated the pamphlet as very good, though improvements in content and timing are warranted. While many men did not report high levels of distress, there remains a concern for a few patients with elevated levels of distress and patients who expressed difficulty accessing counselling support.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 160-167"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Obese young male adults are at high risk for developing medical problems: a community survey of 8080 in Taiwan 台湾一项8080人的社区调查显示,肥胖的年轻男性有较高的健康问题风险
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.03.014
Chung-Hua Hsu MD, PhD , San-Chi Lin MD, MS
{"title":"Obese young male adults are at high risk for developing medical problems: a community survey of 8080 in Taiwan","authors":"Chung-Hua Hsu MD, PhD ,&nbsp;San-Chi Lin MD, MS","doi":"10.1016/j.jomh.2012.03.014","DOIUrl":"10.1016/j.jomh.2012.03.014","url":null,"abstract":"<div><h3>Background</h3><p>Little research effort has been put in to examining the impact of obesity on the young male population.</p></div><div><h3>Method</h3><p><span><span><span>A total of 8080 young male adults, aged 19–23 years, were screened by means of a physical examination. Hypertension, abnormal liver function, proteinuria, </span>glucosuria<span>, anemia and leukocytosis were defined as </span></span>medical problems<span>. The main outcome evaluated among the subjects was the number answering in the affirmative (% yes) for medical problems. All subjects were assigned to a BMI group, which was based on the criteria for the Asian and Pacific region (obesity class II</span></span> <!-->=<!--> <!-->BMI ≥ 30<!--> <!-->kg/m<sup>2</sup>; obesity class I<!--> <!-->=<!--> <!-->25–29.9<!--> <!-->kg/m<sup>2</sup>), for further assessment and comparison.</p></div><div><h3>Results</h3><p>The prevalence of obesity classes I and II was 18.0% and 7.1%, respectively, among the subjects. The obesity class II group had a higher odds ratio for developing hypertension (4.0–6.0 times), abnormal liver function (15.6–23.2 times), glucosuria (1.9–7.8 times) and leukocytosis (3.7–6.0 times); while the obesity class I group had a higher odds ratio for developing hypertension (1.8–2.5 times), abnormal liver function (4.9–6.4 times), glucosuria (1.7–5.3 times) and leukocytosis (0.8–1.4 times) than the reference group (BMI &lt; 23<!--> <!-->kg/m<sup>2</sup>).</p></div><div><h3>Conclusion</h3><p>Our data has reconfirmed the close association between obesity and medical problems in male adults aged 19–23 years, even if they were in a healthy state.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 198-204"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An observational study of plasma vascular endothelial growth factors (VEGF) A and D expression in non-localized prostate cancer 非局限性前列腺癌患者血浆血管内皮生长因子(VEGF) A和D表达的观察性研究
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.04.003
Brandon P. Verdoorn MD , Changyong Feng PhD , William A. Ricke PhD , Deepak M. Sahasrabudhe MD , Deepak Kilari MD , Manish Kohli MD
{"title":"An observational study of plasma vascular endothelial growth factors (VEGF) A and D expression in non-localized prostate cancer","authors":"Brandon P. Verdoorn MD ,&nbsp;Changyong Feng PhD ,&nbsp;William A. Ricke PhD ,&nbsp;Deepak M. Sahasrabudhe MD ,&nbsp;Deepak Kilari MD ,&nbsp;Manish Kohli MD","doi":"10.1016/j.jomh.2012.04.003","DOIUrl":"10.1016/j.jomh.2012.04.003","url":null,"abstract":"<div><h3>Background</h3><p>The aim of the study was to measure plasma levels of the vascular endothelial growth factors (VEGF) A and D in serially collected blood specimens from non-localized prostate cancer (PCa) subjects.</p></div><div><h3>Methods</h3><p>Plasma VEGF A and D levels were measured in two serial specimens 3–6 months apart in two groups of non-localized stage PCa patients. Group 1 was comprised of patients with biochemical relapse<span> after localized PCa treatments and/or patients with clinically metastatic hormone-sensitive stage PCa prior to receiving hormonal therapy. Group 2 included patients failing hormonal therapy for non-localized hormone-sensitive stage PCa. VEGF A and D levels were compared within each cancer group between the two time-points using the Wilcoxon Rank Sum test.</span></p></div><div><h3>Results</h3><p>At the first time-point in Group 1 (<em>n</em> <!-->=<!--> <!-->46), median VEGF-A and D levels were measured at 5.2 (pg/ml) (range<!--> <!-->=<!--> <!-->0–97) and 319 (range<!--> <!-->=<!--> <!-->172–780) (pg/ml). For Group 2 (<em>n</em> <!-->=<!--> <!-->34) VEGF-A level was 9.6 pg/ml (range<!--> <!-->=<!--> <!-->0–78) and VEGF-D level was 377 pg/ml (range<!--> <!-->=<!--> <!-->243–989) for the first measurement. Median time-period for the serial second specimen was 189 days in Group 1 and 84 days in Group 2. At the second time-point, in Group 1, VEGF-A levels were 0.0 pg/ml (<em>P</em> <!-->=<!--> <!-->0.0002) while VEGF-D increased to 349 pg/ml (<em>P</em> <!-->=<!--> <!-->0.002). For Group 2 patients at the second time-point, median VEGF-A was 0.0 pg/ml (<em>P</em> <!-->=<!--> <!-->1.0) and VEGF-D was measured at 442 pg/ml (<em>P</em> <!-->=<!--> <!-->0.008).</p></div><div><h3>Conclusions</h3><p>Higher plasma VEGF-D than VEGF-A expression in advanced PCa stages suggests a greater role for VEGF-D dependent lymph angiogenesis in advanced stage PCa, which needs further evaluation.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 182-189"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32023139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Perceptions of HIV transmission risk in commercial and public sex venues 对商业和公共性场所艾滋病毒传播风险的认识
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.04.002
Martin J. Downing Jr PhD
{"title":"Perceptions of HIV transmission risk in commercial and public sex venues","authors":"Martin J. Downing Jr PhD","doi":"10.1016/j.jomh.2012.04.002","DOIUrl":"10.1016/j.jomh.2012.04.002","url":null,"abstract":"<div><h3>Background</h3><p>Sexual behaviors of men who have sex with men (MSM) that occur in sexually charged venues (e.g., bathhouse, sex club, public park) are a target for research and intervention due to concerns about the role these venues may have in the transmission of HIV and other sexually transmitted infections (STIs). However, these efforts often exclude how individuals perceive HIV risk in terms of sex venue use. This paper analyzes how venue-specific perceptions of HIV transmission risk differ across venues and by onsite sexual behavior.</p></div><div><h3>Method</h3><p>Cross-sectional data collected using an Internet survey completed by 139 MSM who attended at least one sex venue (e.g., bathhouse, sex club, gym/health club, public park) in the past month.</p></div><div><h3>Results</h3><p>Risk perceptions were highest for bathhouses and sex clubs, though no significant differences were detected between any of the venues. With few exceptions, men who reported not engaging in sex or low-risk behaviors (i.e., masturbation or mutual masturbation) during venue attendance perceived higher risks than those who engaged in high-risk behaviors (i.e., anal sex). Interestingly, risk perceptions of public bathrooms, parks, and video/buddy booths were lower for attendees who reported unprotected oral sex with ejaculation than men who reported safer or riskier behaviors.</p></div><div><h3>Conclusion</h3><p>These findings provide important insights into how MSM perceive HIV risk in sex venues and highlight a need for expanded outreach and education in locations where sexual risk taking may be underestimated.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 176-181"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31043889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Illness perceptions among osteoporotic men and women: correlates and gender differences 骨质疏松症男性和女性的疾病认知:相关性和性别差异
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.03.012
Offer Emanuel Edelstein PhD , Perla Werner PhD , Rivka Dresner-Pollak MD , Karen Tordjman MD , Anat Jaffe MD , Yoel Toledano MD , Iris Vered MD
{"title":"Illness perceptions among osteoporotic men and women: correlates and gender differences","authors":"Offer Emanuel Edelstein PhD ,&nbsp;Perla Werner PhD ,&nbsp;Rivka Dresner-Pollak MD ,&nbsp;Karen Tordjman MD ,&nbsp;Anat Jaffe MD ,&nbsp;Yoel Toledano MD ,&nbsp;Iris Vered MD","doi":"10.1016/j.jomh.2012.03.012","DOIUrl":"10.1016/j.jomh.2012.03.012","url":null,"abstract":"<div><h3>Background</h3><p>Although osteoporosis is a major public concern, little research attention has been paid to evaluating the manner in which osteoporotic patients perceive their illness.</p><p>The aim of the current study was to examine osteoporotic patients’ cognitive and emotional illness representations and to see, specifically, if any differences could be correlated with gender.</p></div><div><h3>Methods</h3><p>A convenience sample of 102 women and 100 men (mean age 66 years in both groups) who were diagnosed with osteoporosis, and who were attending bone and mineral clinics at four major medical centers in Israel, participated in the study. Participants were interviewed face-to-face at the clinics or in their homes, using an adapted version of the Illness Perceptions Questionnaire (IPQ). Emotional illness representations were assessed using the state anxiety subscale from the State-Trait Personality Inventory (SPTI).</p></div><div><h3>Results</h3><p>Participants perceived osteoporosis as a chronic but controllable disease. They perceived the disease as having few symptoms and mild consequences on their lives.</p></div><div><h3>Conclusions</h3><p>Osteoporotic patients maintained a logical cognitive and emotional structure of their illness. Regarding gender differences, findings showed that women were more pessimistic than men regarding most of the illness representations’ dimensions. Gender differences in illness representations suggest women and men may benefit from different intervention programs, tailored according to their unique perceptions.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 168-175"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Men suffer more complications from diabetes than women despite similar glycaemic control and a better cardiovascular risk profile: the ADCM study 2008 2008年ADCM研究显示,尽管男性的血糖控制相似,心血管风险也较好,但男性患糖尿病的并发症比女性多
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.02.004
Chew Boon How MD, MMed (Fam Med) , Cheong Ai-Theng MBBS, MMed (Fam Med) , Zaiton Ahmad MD, MMed (Fam Med) , Mastura Ismail MBBS, MMed (Fam Med)
{"title":"Men suffer more complications from diabetes than women despite similar glycaemic control and a better cardiovascular risk profile: the ADCM study 2008","authors":"Chew Boon How MD, MMed (Fam Med) ,&nbsp;Cheong Ai-Theng MBBS, MMed (Fam Med) ,&nbsp;Zaiton Ahmad MD, MMed (Fam Med) ,&nbsp;Mastura Ismail MBBS, MMed (Fam Med)","doi":"10.1016/j.jomh.2012.02.004","DOIUrl":"10.1016/j.jomh.2012.02.004","url":null,"abstract":"<div><h3>Background</h3><p>Gender differences in glycaemic control and diabetes’ complications have been well studied overseas but not locally. Gender is one of the non-modifiable factors for the diabetes patient but it is an important factor for effective personalized diabetes care. This paper examined the gender differences in glycaemic control and diabetes’ complications.</p></div><div><h3>Methods</h3><p>This was a registry-based observational study from May–December 2008. An online standard case record form was available for site data providers to register their diabetes patients aged 18 years old and above annually. Demographic data, diabetes duration, treatment modalities, as well as various risk factors and diabetes complications<span> were reported. Multivariate analysis was performed.</span></p></div><div><h3>Results</h3><p>A total of 20,646 diabetes patients were included. The majority (99.2%) had been diagnosed with type 2 diabetes mellitus (T2D); 42.8% of the sample were men; 57.1% were Malay. The mean age was 58.0 years (standard deviation (SD)<!--> <!-->=<!--> <span><span>11.49) with 77.6% of the sample being 50 years old and above. Despite similar diabetes control (HbA1c &lt; 6.5%), females suffered more microvascular complications (estimated </span>glomerular filtration rate (eGFR) &lt;60 mls/min: X</span><sup>2</sup> <!-->=<!--> <!-->753.54, <em>P</em> <!-->=<!--> <!-->&lt;0.001) while men suffered more from macrovascular complications (ischaemic heart disease (X<sup>2</sup> <!-->=<!--> <!-->57.61, <em>P</em> <!-->=<!--> <!-->&lt;0.001) and stroke (X<sup>2</sup> <!-->=<!--> <!-->13.87, <em>P</em> <!-->=<!--> <span>&lt;0.001)). Multivariate logistic regression analyses showed that T2D men were more likely to suffer from stroke (odds ratio (OR)</span> <!-->=<!--> <!-->1.21, 95% confidence interval (CI)<!--> <!-->=<!--> <span>0.89–1.64), ischaemic heart disease (OR</span> <!-->=<!--> <!-->1.55, CI<!--> <!-->=<!--> <span>1.35–1.78) and nephropathy (OR</span> <!-->=<!--> <!-->1.59, CI<!--> <!-->=<!--> <!-->1.44–1.75).</p></div><div><h3>Conclusion</h3><p>We observed that men suffered more diabetes-related complications despite similar glycaemic control and better risk factor control. This finding requires further verification from future studies.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 190-197"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.02.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Erectile dysfunction and testosterone deficiency as gender-specific markers of cardiometabolic risk in minority and non-minority men: potential role of social determinants 勃起功能障碍和睾酮缺乏作为少数和非少数男性心脏代谢风险的性别特异性标记:社会决定因素的潜在作用
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.03.008
Kevin L. Billups MD
{"title":"Erectile dysfunction and testosterone deficiency as gender-specific markers of cardiometabolic risk in minority and non-minority men: potential role of social determinants","authors":"Kevin L. Billups MD","doi":"10.1016/j.jomh.2012.03.008","DOIUrl":"10.1016/j.jomh.2012.03.008","url":null,"abstract":"<div><p><span><span>Evaluation of cardiometabolic risk has become vital in the primary prevention of adverse vascular events (coronary artery disease, heart attack, stroke or congestive heart failure), particularly in younger middle-aged men (aged 40–60 years old). To discern the prevalence of events in these men, clinicians often stratify cardiovascular risk and treat according to traditional </span>Framingham risk criteria. The Framingham Risk Score (FRS) is a useful and often used tool for estimating the 10-year risk for myocardial infarction or coronary death of an individual. It is supported by the 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults. The FRS is based on data obtained from the Framingham Heart Study and it incorporates age, gender, total and high-density lipoprotein (HDL) cholesterol, smoking, </span>systolic blood pressure<span><span> (BP), and use of antihypertensive<span> medications. However, it is important to note that the Framingham study includes few data from patients &lt;40 years of age and few minority patients (African American and Hispanic). Thus, the FRS may not adequately estimate risk in younger patients and minorities. The FRS also lacks some important risk factors (e.g., family history, fasting glucose, testosterone) that should be considered when estimating cardiovascular risk in the man with ED<span><span>. It is evident that the traditional Framingham risk assigned to intermediate and low-risk men will miss several of these individuals deemed at high “cardiometabolic risk”, also known as residual cardiovascular risk. This review will elaborate the definition of cardiometabolic risk, and apply the use of erectile dysfunction and testosterone deficiency as gender-specific surrogate markers for cardiovascular </span>risk stratification in men in addition to the traditional Framingham-based markers. Lastly, it will examine minority </span></span></span>men's health<span>, racial differences and the need to include the role of social determinants in future research studies of cardiovascular risk.</span></span></p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 139-145"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Testosterone and abnormal glucose metabolism in an inner-city cohort 市中心人群的睾酮和异常糖代谢
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.03.010
Anne K. Monroe MD, MSPH , Adrian S. Dobs MD, MHS , Joseph Cofrancesco Jr MD, MPH , Todd T. Brown MD, PhD
{"title":"Testosterone and abnormal glucose metabolism in an inner-city cohort","authors":"Anne K. Monroe MD, MSPH ,&nbsp;Adrian S. Dobs MD, MHS ,&nbsp;Joseph Cofrancesco Jr MD, MPH ,&nbsp;Todd T. Brown MD, PhD","doi":"10.1016/j.jomh.2012.03.010","DOIUrl":"10.1016/j.jomh.2012.03.010","url":null,"abstract":"<div><h3>Background</h3><p>Low testosterone (T) has been associated with insulin resistance and diabetes mellitus (DM) among men in population-based studies. These studies included racially diverse men, but did not target for inclusion individuals with opiate use, Hepatitis C Virus (HCV) infection, or Human Immunodeficiency Virus (HIV) infection, which disproportionately affect inner-city populations and may alter the relationship between T and DM.</p></div><div><h3>Methods</h3><p><span>The association between free T (FT) and abnormal glucose metabolism was studied among male participants in the Study of HIV, Injection Drug Use, Nutrition, and </span>Endocrinology<span> (SHINE). Logistic regression was used to examine the relationship between log FT and both insulin resistance and prediabetes/DM.</span></p></div><div><h3>Results</h3><p><span>Of 175 men, 43 (24.6%) had low levels of FT (&lt; 52 pg/ml). There were more men in the low FT group on methadone maintenance (39.5% vs. 15.2%, </span><em>P</em> <!-->=<!--> <span>0.001), but there was no difference in FT by HIV or HCV status. Overall, 23 men (13.1%) had prediabetes/DM, which was unrelated to FT (odds ratio (OR) of prediabetes/DM for each log increase in FT</span> <!-->=<!--> <!-->0.56, 95% Confidence Interval (CI)<!--> <!-->=<!--> <!-->0.13–2.41). FT was also not related to insulin resistance.</p></div><div><h3>Conclusions</h3><p>The prevalence of hypogonadism<span> was high in this inner-city cohort and was associated with methadone use. However, low FT was not related to insulin resistance or prediabetes/DM. Continued work to identify diabetes risk factors among inner-city populations will help determine targets for intervention to reduce diabetes incidence. Treatment trials of testosterone to reduce diabetes among hypogonadal men may be of particular relevance to opiate users, many of whom are hypogonadal.</span></p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 154-159"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40279866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Male breast cancer 男性乳腺癌
IF 0.7 4区 医学
Journal of Mens Health Pub Date : 2012-09-01 DOI: 10.1016/j.jomh.2012.03.013
Nicole P. Sandhu MD, PhD , Marie Brid Mac Bride MB, BCh , Christina A. Dilaveri MD , Lonzetta Neal MD , David R. Farley MD , Charles L. Loprinzi MD , Dietlind L. Wahner-Roedler MD , Karthik Ghosh MD, MS
{"title":"Male breast cancer","authors":"Nicole P. Sandhu MD, PhD ,&nbsp;Marie Brid Mac Bride MB, BCh ,&nbsp;Christina A. Dilaveri MD ,&nbsp;Lonzetta Neal MD ,&nbsp;David R. Farley MD ,&nbsp;Charles L. Loprinzi MD ,&nbsp;Dietlind L. Wahner-Roedler MD ,&nbsp;Karthik Ghosh MD, MS","doi":"10.1016/j.jomh.2012.03.013","DOIUrl":"10.1016/j.jomh.2012.03.013","url":null,"abstract":"<div><p>Male breast cancer is rare, and many patients and health care providers are not familiar with this entity. Although the underlying causes are not well understood, certain populations are at higher risk, including certain gene mutation carriers, men with Klinefelter syndrome, and certain ethnic groups. Male breast cancer typically presents at a later stage than female breast cancer. A palpable mass is the most common presentation, but nipple discharge or other nipple changes may be seen. Because the number of affected individuals is small, prospective trials have not been conducted; thus, treatment recommendations are typically taken from large trials involving female breast cancer populations. Although outcomes in male breast cancer were previously thought to be worse than female breast cancer outcomes, it appears that they are similar. Questions regarding the most effective surgical and adjuvant therapies remain. Mastectomy with axillary lymph node evaluation, adjuvant hormonal therapy, and chemotherapy are commonly used. Providers of health care to male patients must be aware of the possibility of breast cancer and appropriately evaluate any suspicious changes.</p></div>","PeriodicalId":54391,"journal":{"name":"Journal of Mens Health","volume":"9 3","pages":"Pages 146-153"},"PeriodicalIF":0.7,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jomh.2012.03.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54625546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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