Quantitative Imaging in Medicine and Surgery最新文献

{"title":"Ultrasonographic and magnetic resonance imaging findings of hepatic ascariasis: a case description of an adult.","authors":"Shuyuan Tian, Jiaqi Hu, Qing Pan, Dong Xu","doi":"10.21037/qims-24-1805","DOIUrl":"10.21037/qims-24-1805","url":null,"abstract":"","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 3","pages":"2666-2670"},"PeriodicalIF":2.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound diagnosis of parathyroid adenomas mimicking normal lymph nodes: microvascular clues.","authors":"Song Fang, Qingli Zhu, Jialin Zhao, Xiaoyan Chang, Quan Liao, Ou Wang, Xiaoping Xing, Jianchu Li, He Liu","doi":"10.21037/qims-24-2057","DOIUrl":"10.21037/qims-24-2057","url":null,"abstract":"<p><strong>Background: </strong>Ultrasound (US) is the preferred imaging modality for preoperative localization of primary hyperparathyroidism (PHPT). Parathyroid adenomas may be confused with normal lymph nodes on conventional US. This study aimed to explore the usefulness of microvascular flow imaging (MVFI) in differentiating parathyroid adenomas from normal lymph nodes and compare it with color Doppler flow imaging (CDFI).</p><p><strong>Methods: </strong>A total of 34 parathyroid adenomas that appeared peripherally hypoechoic and internally hyperechoic mimicking normal lymph nodes were identified in 34 patients with PHPT, and 34 cervical level III normal lymph nodes from 34 healthy controls were selected for comparison. The ability of CDFI and MVFI to detect the vascular characteristics of parathyroid adenomas were compared.</p><p><strong>Results: </strong>On CDFI, the detection rates of polar vessels, hilar vessels, and rich vascular in parathyroid adenomas were 44.1%, 8.8%, and 52.9%, respectively. These characteristics in normal lymph nodes showed detection rates of 2.9%, 38.2%, and 8.8%, respectively. On MVFI, the detection rates of polar vessels, hilar vessels, and rich vascular in parathyroid adenomas were 82.4%, 5.9%, and 94.1%, respectively. For normal lymph nodes, the detection rates of these characteristics were 5.9%, 76.5%, and 11.8%, respectively. Compared with CDFI, MVFI detected a significantly higher rate of polar vessels and rich vascularity in parathyroid adenomas (82.4% <i>vs.</i> 44.1% and 94.1% <i>vs.</i> 52.9%, P=0.034 and P<0.001), as well as hilar vessels in normal lymph nodes (76.5% <i>vs.</i> 38.2%, P<0.001).</p><p><strong>Conclusions: </strong>MVFI more frequently identified polar vessels and rich vascularity in parathyroid adenomas, as well as hilar vessels in lymph nodes, compared to CDFI. This suggests that MVFI may play a better role in differentiating parathyroid adenomas from lymph nodes, contributing to surgical planning in PHPT cases.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 3","pages":"2222-2231"},"PeriodicalIF":2.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-assisted compressed sensing MRI improves imaging quality in rectal cancer: a comparative study with conventional acceleration techniques.","authors":"Guangying Zheng, Junyi Fu, Zhe Wang, Wei Li, Aiyin Li, Dan Yu","doi":"10.21037/qims-24-1317","DOIUrl":"10.21037/qims-24-1317","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI)-assisted compressed sensing (ACS) is widely used in various parts of the body, but the application of this technology in the rectum is still rare. This study aimed to evaluate the feasibility of super-resolution (SR) T2-weighted imaging (T2WI) based on ACS in rectal cancer (RC) by comparing with compressed sensing (CS) and parallel imaging (PI).</p><p><strong>Methods: </strong>In this prospective study, 29 patients with rectal adenocarcinoma were enrolled, and three groups of SR rectal T2WI images based on ACS, CS, and PI (ACS-T2WI, CS-T2WI, and PI-T2WI) were obtained, using the same scanning time for each group. Two radiologists independently assessed the visibility of structures, tissue edge sharpness, image artifacts, overall image quality, and confidence in N staging for the three sequences using a five-point Likert scale; the scores of the three sequences were compared and the agreement between two readers was assessed. In addition, the quantitative parameters of the three groups, sharpness, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were compared. T staging based on magnetic resonance imaging (MRI) was performed by two readers separately using the three sequences combined with other conventional scanning sequences. The consistency between T staging based on MRI (mrT staging) and pathological T staging (PT staging) of the two readers and the diagnostic accuracy of every sequence was compared.</p><p><strong>Results: </strong>The scores of ACS-T2WI were higher in visibility of structures, tissue edge sharpness, overall image quality, and confidence in N staging than CS-T2WI and PI-T2WI (P<0.001). There was no statistical difference in the scores of image artifacts among the three sequences (P=0.18). The sharpness of ACS-T2WI was higher than that of CS-T2WI and PI-T2WI (P<0.001). The SNR of CS-T2WI was slightly higher than that of ACS-T2WI and PI-T2WI (P=0.004). There was no statistically significant difference in CNR among the three sequences (P=0.425). The consistency between mrT staging of ACS-T2WI and PT staging was higher than that of CS-T2WI and PI-T2WI. The two readers had a higher diagnostic accuracy for ACS-T2WI (89.66%) than for CS-T2WI (79.31%) and PI-T2WI (75.86%), but the difference was not statistically significant.</p><p><strong>Conclusions: </strong>By using ACS to increase the resolution through a larger matrix size, higher quality images can be obtained within the same scanning time as traditional acceleration techniques. The SR T2WI based on ACS can be well applied in the clinical scanning of RC.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 3","pages":"2547-2560"},"PeriodicalIF":2.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pancreatic and extra-pancreatic transabdominal ultrasound findings of type 1 autoimmune pancreatitis.","authors":"Ya-Na Yu, Peng Cong, Xue-Mei Wang, Yun-Fei Zhang","doi":"10.21037/qims-24-110","DOIUrl":"10.21037/qims-24-110","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune pancreatitis (AIP) is an important manifestation of immunoglobulin G4 (IgG4)-related diseases with multi-organ involvement. This study sought to retrospectively analyze pancreatic and extra-pancreatic ultrasonography findings in patients with AIP, and to determine the value of transabdominal ultrasound (TUS) in the diagnosis of AIP.</p><p><strong>Methods: </strong>In total, 19 patients with type 1 AIP (12 males and seven females; mean age: 52.84±15.33 years; range: 18-83 years) underwent ultrasound examinations of the pancreas, peripancreatic lymph nodes, gall bladder, bile ducts, retroperitoneal, kidneys, and submandibular and lacrimal glands.</p><p><strong>Results: </strong>According to the distribution of the lesions, the pancreatic images were categorized into the following three types: diffuse (n=9), segmental (n=5), and focal (n=5). These images showed diffuse, segmental, or focal enlargement of the pancreas with hypoechoic parenchyma. Contrast-enhanced ultrasound (CEUS) revealed hypoenhancement in the diffuse type. A thick capsule-like echo surrounding the lesion was observed in 12 patients. The main pancreatic duct was dilated in eight patients. No calcification was detected in any of the 19 patients. Peripancreatic lymph nodes were identified in four patients. Vascularity was found in four of eight patients for whom color Doppler flow images (CDFIs) of the pancreas were available. The intrahepatic and common bile ducts were dilated in 11 patients. The gallbladder was found to be involved in 13 patients. Except for one patient with hydronephrosis due to retroperitoneal fibrosis, no abnormalities were observed in the kidneys. Retroperitoneal fibrosis was found in one patient. Among the 12 patients for whom data were available, parenchymal inhomogeneity was observed in the parotid glands of three patients, the submandibular glands of five patients, and the lacrimal glands of eight patients.</p><p><strong>Conclusions: </strong>Ultrasonography is valuable in the diagnosis of AIP. In addition to TUS, other ultrasound technologies, such as CEUS and TUS-guided biopsy, could also play a crucial role in the diagnosis of AIP.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 3","pages":"2561-2569"},"PeriodicalIF":2.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance imaging-based bone and muscle quality parameters for predicting clinical subsequent vertebral fractures after percutaneous vertebral augmentation.","authors":"Chengxin Liu, Quan Yu, Zhaochuan Zhang, Weixiang Dai, Youdi Xue","doi":"10.21037/qims-24-712","DOIUrl":"10.21037/qims-24-712","url":null,"abstract":"<p><strong>Background: </strong>Clinical subsequent vertebral fracture (SVF) is a common complication following percutaneous vertebral augmentation treatment for osteoporotic vertebral compression fracture. Magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score, cross-sectional area (CSA), and degree of fat infiltration (DFI) of paravertebral muscles are effective predictors of spinal surgery-related complications. However, the relationship between these parameters and SVF remains unclear. The purpose of this study was to evaluate the utility of these MRI-based bone and muscle quality parameters for predicting SVF after percutaneous vertebral augmentation.</p><p><strong>Methods: </strong>This retrospective study included consecutive patients with osteoporotic vertebral compression fracture treated with percutaneous vertebral augmentation at Xuzhou Central Hospital between January 2017 and December 2020. Clinical SVF was diagnosed if there was new episode of back pain and a confirmed acute fracture on MRI. Noncontrast T1-weighted MRI and axial T2-weighted MRI were used to determine the VBQ score and measure CSA and DFI, respectively. A multivariable logistic regression analysis adjusted for confounding factors was performed to determine the correlation between VBQ score, DFI, CSA, and SVF. Receiver operating characteristic curves were plotted, and the area under the curve (AUC) was calculated to evaluate the predictive ability of SVF. The DeLong test was used to compare the predictive ability. Pearson correlation analysis was used to characterize the relationships between VBQ score and both CSA and DFI.</p><p><strong>Results: </strong>A total of 289 patients were included in this study, and 41 (14.2%) patients developed SVF. Compared with the non-SVF group, the SVF group had a higher VBQ score (3.83 <i>vs.</i> 3.28; P<0.05) and DFI (66.3% <i>vs.</i> 44.1%; P<0.001). The multivariable regression analysis revealed that a higher VBQ score [odds ratio (OR) =3.66; P<0.001] and DFI (OR =3.72; P<0.001) were associated with SVF. The AUC of the VBQ score was 0.863 (cutoff =3.49). Similarly, the AUC of DFI was 0.851 (cutoff =48.2%). The AUC for the combination of VBQ score and DFI in predicting SVF was 0.925 (P<0.001). According to the Delong test, the AUC of the combined model was higher than that of the VBQ score alone (0.925 <i>vs.</i> 0.863; P=0.0389) and DFI alone (0.925 <i>vs.</i> 0.851; P=0.0254). The Pearson correlation showed that the VBQ score was positively correlated with DFI (r=0.647; P<0.001) while no significant correlation was present between the VBQ score and CSA (r=-0.039; P=0.7495).</p><p><strong>Conclusions: </strong>The VBQ score and DFI were independent predictors for clinical SVF after percutaneous vertebral augmentation. The combination of VBQ score and DFI significantly improved the predictive accuracy. Moreover, there was a significant positive correlation between the VBQ score and DFI.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 2","pages":"1480-1490"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-stop combined coronary-craniocervical computed tomography angiography with low-dose body coverage using artificial intelligence iterative reconstruction: a clinically feasible solution to multi-territorial atherosclerosis diagnosis.","authors":"Rui Guo, Song Peng, Wanhui Zhou, Guozhi Zhang, Pengfei Rong, Qi Liang, Roumei Peng, Jiao Deng, Pengzhi Hu","doi":"10.21037/qims-24-1545","DOIUrl":"10.21037/qims-24-1545","url":null,"abstract":"<p><strong>Background: </strong>Computed tomography angiography (CTA) is an effective means to detect atherosclerosis yet a whole-body scan may involve excessive dose that can only be considered in extreme cases. This study is to test the feasibility and value of adding a low-dose body CTA to the combined coronary-craniocervical CTA by using artificial intelligence iterative reconstruction (AIIR).</p><p><strong>Methods: </strong>A total of 100 patients scheduled for one-stop combined coronary-craniocervical CTA were enrolled to receive an extended CTA covering from intracranial to iliofemoral arteries, by adding a low-dose body CTA to the coronary-craniocervical CTA. Radiation dose, contrast medium volume and the resulting image quality of the added scan, reconstructed by the AIIR, were compared to those from the retrospectively collected routine-dose aortic CTA. Diagnostic findings beyond the coronary and craniocervical arteries, which would have been missed if not for the extension, and their influence on clinical management, were assessed on the low-dose images.</p><p><strong>Results: </strong>With rather low cost of radiation and contrast dosage (1.6 mSv, 25.4 mL), the body CTA with AIIR reconstruction yielded diagnostically sufficient image quality and significantly higher contrast-to-noise ratio (CNR) as compared to routine-dose aortic CTA at various vascular locations (all P<0.05). Additional atherosclerosis was detected by the added low-dose body CTA for a substantial proportion of patients (73/100, 73%). Incidental findings in the body were found in 26 patients with 44 detections. The corresponding clinical management of 38% patients was changed due to the atherosclerotic and non-atherosclerotic vascular findings on body arteries. Most of the atherosclerosis were calcified plaques (38/73, 52%) and rated as mild stenosis (62/73, 85%). The prevalence of body arterial atherosclerosis was remarkably higher among patients diagnosed with coronary-craniocervical atherosclerosis than those without coronary-craniocervical atherosclerosis (85% <i>vs.</i> 22%).</p><p><strong>Conclusions: </strong>Extending the one-stop combined coronary-craniocervical CTA with low-dose body coverage as enabled by the AIIR is technically feasible and of evident clinical value in clinical decision-making, taking a concrete step towards multi-territorial atherosclerosis diagnosis and management in practical application.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 2","pages":"1516-1527"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of diffusion tensor imaging along the perivascular space index with cognitive impairment in type 2 diabetes mellitus.","authors":"Pengxin Hu, Yu Zou, Mingyu Zhou, Jiankun Dai, Xiaoping Tang","doi":"10.21037/qims-24-1591","DOIUrl":"10.21037/qims-24-1591","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Type 2 diabetes mellitus (T2DM) often coexists with cognitive impairment, but the exact mechanisms underlying this relationship remain unclear. Glymphatic dysfunction may be a significant factor contributing to cognitive impairment. This study aimed to assess the changes in diffusion tensor imaging along the perivascular space (DTI-ALPS) index in patients with T2DM and to determine its association with cognitive impairment and whole-brain white-matter damage.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We prospectively recruited patients with T2DM and healthy controls (HCs) for a case-control study in which all participants underwent cognitive assessments and underwent magnetic resonance imaging (MRI) scans. We calculated the DTI-ALPS index of HCs and patients with T2DM based on the DTI. Furthermore, we calculated whole-brain fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), radial diffusivity (RD), and structural connectivity parameters, including the average clustering coefficient (Cp), characteristic path length (Lp), global efficiency (Eglob), and small-world index (Sigma) to assess brain white-matter damage. A general linear model was used to analyze the differences between the groups, which was followed by multiple linear regression analysis to examine the relationship among the DTI-ALPS index, MRI parameters, and cognitive function.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;This study enrolled 70 patients with T2DM (age 66.37±9.85 years; 48 males) and 35 HCs (age 64.03±11.26 years; 21 males). There were 35 patients with T2DM with mild cognitive impairment (T2DM-MCI). The DTI-ALPS index and whole-brain FA of patients with T2DM were reduced, while the whole-brain MD, AD, and RD were increased, especially in patients with T2DM-MCI. The Eglob of structural connectivity was decreased and Lp increased in patients with T2DM. No significant differences were found in the Cp or the Sigma between the T2DM group and HCs. We found that in the patients with T2DM, the DTI-ALPS index was associated with Montreal Cognitive Assessment [β =0.577; 95% confidence interval (CI): 0.360 to 0.793; P false discovery rate (P&lt;sub&gt;FDR&lt;/sub&gt;)&lt;0.001], FA (β =0.340; 95% CI: 0.069 to 0.611; P&lt;sub&gt;FDR&lt;/sub&gt;=0.043), MD (β =-0.338; 95% CI: -0.610 to -0.065; P&lt;sub&gt;FDR&lt;/sub&gt;=0.043), AD (β =-0.440; 95% CI: -0.712 to -0.168; P&lt;sub&gt;FDR&lt;/sub&gt;=0.016), and RD values (β =-0.313; 95% CI: -0.581 to -0.044; P&lt;sub&gt;FDR&lt;/sub&gt;=0.046). No association was found between the DTI-ALPS index and the structural connectivity parameters. In addition, mediation analysis showed that FA partially mediated the association of decreased DTI-ALPS index with cognitive impairment in patients with T2DM (β =0.086; mediation effect 14.86%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Our study demonstrated that the DTI-ALPS index is decreased in patients with T2DM, especially in those with T2DM-MCI. A decrease in DTI-ALPS index is associated with cognitive impairment and whole-brain w","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 2","pages":"1491-1504"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eyeball descending identification using MRI-based spatial coordinates in thyroid-associated orbitopathy patients with unilateral upper eyelid retraction.","authors":"Xinyi Gou, Yi Wang, Tianyuan Li, Lingli Zhou, Jianxiu Lian, Xiuying Zhang, Mengjie Fan, Liang Zhou, Jin Cheng, Nan Hong","doi":"10.21037/qims-24-1659","DOIUrl":"10.21037/qims-24-1659","url":null,"abstract":"<p><strong>Background: </strong>Upper eyelid retraction (UER), the primary symptom of thyroid-associated orbitopathy (TAO), can affect perceived eyeball position. This study aimed to assess relative anatomical positions, and examine changes in eyeball position and related factors in TAO patients with unilateral UER.</p><p><strong>Methods: </strong>In total, 30 TAO patients with unilateral UER and 67 healthy control participants were included in this retrospective study. Using orbital magnetic resonance images, image processing techniques were employed to measure the difference between the vertical distance of the eyeballs for each patient and each healthy control participant. The thickness of the levator palpebrae superioris (LPS), superior rectus (SR), and inferior rectus (IR) muscles, and the volume of the LPS-SR complex were measured in the patient cohort.</p><p><strong>Results: </strong>In the healthy control group, the vertical distance difference between the eyeballs was -0.067±0.938 mm (P=0.560). In the patient group, the descent distance difference was 1.192±1.159 mm (P<0.001). The increase in the thickness of the LPS muscle was greater in the patients with a descent difference (n=25) than those without a descent difference (n=5; P<0.001). The descent distance in the impaired eyes was positively correlated with an increased thickness of the LPS muscle (P<0.001). No significant correlations were observed between the descent distance and the increased thickness of the SR muscle, the increased thickness of the IR muscle, or the volume of the LPS-SR complex.</p><p><strong>Conclusions: </strong>In TAO patients with unilateral UER, the eyeball of the affected side had a descent difference, which was associated with a thickening of the LPS muscle.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 2","pages":"1287-1296"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of two-dimensional speckle-tracking echocardiography in the assessment of left atrial function in patients with chronic kidney disease.","authors":"Xiaohua Liu, Guijuan Peng, Ying Guo, Shuyu Luo, Qian Liu, Xiaofang Zhong, Yuanyuan Sheng, Yuxiang Huang, Xiaoxuan Lin, Lixin Chen, Jinfeng Xu, Yingying Liu","doi":"10.21037/qims-24-1537","DOIUrl":"10.21037/qims-24-1537","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The rising prevalence of chronic kidney disease (CKD) has emerged as a global public health concern, posing a significant threat to human health. This study aimed to assess changes in left atrial (LA) function in patients with CKD with left ventricular hypertrophy (LVH) using two-dimensional speckle-tracking echocardiography (2D-STE) and to investigate the independent correlations between baseline parameters and LA strain and strain rate.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted a prospective study that included patients diagnosed with CKD at Shenzhen People's Hospital between November 2020 and September 2021. Healthy participants were enrolled as a healthy control group. Conventional transthoracic echocardiography was performed to obtain conventional ultrasound parameters, with cines analyzed offline to determine strain and strain rate parameters. Single-factor analysis of variance was used to compare the groups. The relationship between different variables and LA strain and strain rate was analyzed by general linear regression. The relationship between left ventricular mass index (LVMI) and LA strain and strain rate was analyzed by multifactor linear regression.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study included 236 participants: 166 patients with CKD (85 in the CKD&lt;sub&gt;non-LVH (N-LVH)&lt;/sub&gt; group and 81 in the CKD&lt;sub&gt;LVH&lt;/sub&gt; group) and 70 healthy controls (CON group). The results showed that LA volume in the CKD&lt;sub&gt;N-LVH&lt;/sub&gt; group was not significantly different compared with that in the CON group (P&gt;0.05), but the remaining LA strain and strain rate parameters were decreased (P&lt;0.05), except for the LA global longitudinal strain during early diastole (LA Se) and LA global longitudinal strain rate during late diastole (LA SRa) (P&gt;0.05). In the CKD&lt;sub&gt;LVH&lt;/sub&gt; group, LA strain and strain rate were further reduced as compared to those in the CKD&lt;sub&gt;N-LVH&lt;/sub&gt; group (P&lt;0.05). Additionally, LA strain and strain rate were negatively correlated with age [&lt;i&gt;vs&lt;/i&gt;. LA global longitudinal strain during systole (LA Ss): R=-0.36, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA global longitudinal strain rate during systole (LA SRs): R=-0.24, P&lt;0.001], systolic blood pressure (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=-0.38, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=-0.43, P&lt;0.001), A peak (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=-0.36, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=-0.34, P&lt;0.001), E/&lt;i&gt;e'&lt;/i&gt; (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=-0.44, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=-0.54, P&lt;0.001), LA volume index (LAVI) (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=-0.35, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=-0.52, P&lt;0.001), and LVMI (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=-0.46, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=-0.55, P&lt;0.001); meanwhile, LA strain and strain rate were positively correlated with glomerular filtration rate (GFR) (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=0.50, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=0.50, P&lt;0.001) and &lt;i&gt;e'&lt;/i&gt; (&lt;i&gt;vs&lt;/i&gt;. LA Ss: R=0.58, P&lt;0.001; &lt;i&gt;vs.&lt;/i&gt; LA SRs: R=0.54, P&lt;0.001). LVMI had an independent negative effect on all LA strain and strain rates (&lt;i&gt;vs&lt;/i&gt;","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 2","pages":"1212-1228"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of anemia on left ventricular function and deformation in patients with essential hypertension: a cardiac magnetic resonance study.","authors":"Bi-Yue Hu, Zhi-Gang Yang, Si-Shi Tang, Xiao-Ling Wen, Wei-Feng Yan, Shi-Qin Yu, Yuan Li","doi":"10.21037/qims-24-1768","DOIUrl":"10.21037/qims-24-1768","url":null,"abstract":"<p><strong>Background: </strong>Hypertension (HTN) and anemia contribute to left ventricular (LV) hypertrophy and are associated with adverse outcomes. Anemia is often overlooked in patients with HTN, and its combined impact on the heart may be underestimated. The study aims to investigate the additive effects of anemia on LV function and global strains in individuals with essential HTN, utilizing cardiac magnetic resonance (CMR) imaging.</p><p><strong>Methods: </strong>A total of 238 patients diagnosed with HTN and 67 sex- and age-matched controls who underwent CMR examination were retrospectively included. All HTN patients were divided into two groups: 88 with anemia and 150 without anemia. LV performance was evaluated using CMR including LV function parameters, LV global radial peak strain (GRPS), global circumferential peak strain (GCPS), and global longitudinal peak strain (GLPS). Comparisons among the three groups were conducted using one-way analysis of variance (ANOVA), the Kruskal-Wallis test, or the Chi-squared test. Additionally, multivariable linear regression analysis was performed to investigate factors associated with LV global strains.</p><p><strong>Results: </strong>The HTN patients with anemia were older and had lower hemoglobin concentration and estimated glomerular filtration rate, and higher indices for LV end-diastolic volume, end-systolic volume, mass index, and mass/volume ratio compared with the control group and HTN without anemia group (all P<0.001). Additionally, the GLPS and GCPS deteriorated progressively from the HTN without anemia group to the HTN with anemia group when compared with the control group (all P<0.001). After adjusting for age, GLPS (-10.40%±0.46% <i>vs.</i> -11.95%±0.35%, P=0.008), GCPS (-16.60%±0.52% <i>vs.</i> -18.08%±0.39%, P=0.025), and GRPS (28.95%±1.49% <i>vs.</i> 32.72%±1.14%, P=0.048) were significantly poorer in HTN patients with anemia compared with those without anemia. Furthermore, multivariate analysis revealed significant independent associations between anemia and GLPS (β =0.308, P=0.002), GCPS (β =0.273, P=0.004), and GRPS (β =-0.142, P=0.021).</p><p><strong>Conclusions: </strong>Anemia has additive deleterious effects on LV function and global strains in patients with HTN. Regular monitoring and early intervention of anemia might be beneficial for patients with HTN.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"15 2","pages":"1332-1345"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}