Practical Radiation Oncology最新文献

{"title":"Not Just a Doctor, But a Friend.","authors":"Ajitesh Avinash, Kanhu Charan Patro","doi":"10.1016/j.prro.2025.05.003","DOIUrl":"https://doi.org/10.1016/j.prro.2025.05.003","url":null,"abstract":"","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Society for Women in Radiation Oncology Five Years Later: Connection, Representation, and Inclusivity Matter.","authors":"Rebecca Krc, Claire C Baniel, Katie Lichter, Simran Jatar, Gabrielle W Peters, Crystal Seldon Taswell, Sara Beltrán Ponce, Emily MacDuffie, Michael C LeCompte, Jie Jane Chen, Kaidi Wang, Amy LoTemplio, Anjali Saripalli, Erin Kaya, Parul Barry, Adrianna Henson Masters, Reshma Jagsi, Jenna M Kahn","doi":"10.1016/j.prro.2025.05.005","DOIUrl":"https://doi.org/10.1016/j.prro.2025.05.005","url":null,"abstract":"<p><strong>Background: </strong>The Society for Women in Radiation Oncology (SWRO) was founded in 2017 with a mission to promote representation and gender equity in the field of Radiation Oncology (RO). We aimed to assess the current experiences of SWRO members 5 years after the founding of SWRO using a comprehensive survey of gender-related workforce issues.</p><p><strong>Methods: </strong>From January to February 2023, an anonymous survey was distributed to all current SWRO members. Questions included demographics, family planning/fertility issues, perceptions of the field, and membership needs. Results pertaining to demographics, job satisfaction, mentorship, SWRO membership satisfaction, and future directions are reported in this analysis. Descriptive statistics were used to summarize frequencies of the multiple-choice items on the survey.</p><p><strong>Results: </strong>The survey was distributed to 461 SWRO members, with a total of 144 responses, resulting in a response rate of 31.3%. The majority of respondents identified as female (96.5%), RO attending physicians (54.2%), located in the United States (76.4%), and with employment in either a private or community-based practice (50.7%). Top reasons for SWRO membership included networking (91%), leadership/professional development (83%), and mentorship (79%). After clinical responsibilities, insufficient institutional mentorship was cited as the second most common limitation to professional productivity, and only a minority of respondents (46.5%) reported being either \"extremely\" or \"somewhat\" satisfied with the current mentorship available to them at their current institution. A majority (69.3%) reported seeking female mentorship outside their current institution. Unwanted sexual comments, attention, or advances by superiors or colleagues was reported by 35.7% of respondents, and 53.6% reported either \"strongly\" or \"somewhat\" agreeing that gender specific biases exist within their program.</p><p><strong>Conclusion: </strong>This study highlights opportunities for improvement related to gender-based obstacles, education and advocacy, support of family-friendly culture shifts, mentorship, and increased physicist engagement which will ultimately promote representation, inclusivity, and gender equity in RO.</p>","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining Radiotherapy with Immune Checkpoint Inhibitors for the Management of Muscle-Invasive Bladder Cancer: A Comprehensive Systematic Review from the Y-ECI ROSC EORTC group.","authors":"Vérane Achard, Hoda Abdel-Aty, Victor Duque Santana, Marko Bebek, Tiuri E Kroese, Miha Orazem, Piet Dirix, Piet Ost, Andrea Lancia","doi":"10.1016/j.prro.2025.05.004","DOIUrl":"https://doi.org/10.1016/j.prro.2025.05.004","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to evaluate the efficacy and safety of combining immune checkpoint inhibitors (ICI) with RT in the treatment of non-metastatic MIBC, focusing on neoadjuvant and bladder preservation strategies.</p><p><strong>Evidence acquisition: </strong>A systematic literature review was conducted from January 2000 to December 2023 using PubMed and Clinicaltrials.gov databases. Studies investigating outcomes after combining immunotherapy with RT for non-metastatic MIBC were selected. Data extraction included study identifiers, patient characteristics, intervention and control arm details, and primary outcomes.</p><p><strong>Evidence synthesis: </strong>Among 28 selected studies, diverse approaches were observed, including neoadjuvant and bladder preservation strategies. Neoadjuvant trials, such as RACE IT, explored the feasibility of combining ICI with RT before radical cystectomy, showing promising efficacy and safety outcomes. In bladder preservation strategies, completed as well as ongoing trials demonstrated acceptable toxicity profiles and promising early efficacy data for combining ICI with chemoradiotherapy or RT alone.</p><p><strong>Conclusion: </strong>Combining ICI with RT holds significant promise as a treatment strategy for non-metastatic MIBC. Preliminary evidence suggests favorable efficacy and safety profiles, supporting further exploration and potential integration into standard care. Ongoing phase III trials will provide crucial insights into the comparative effectiveness of adding ICI to conventional definitive treatments. In the evolving landscape of MIBC management, the combination of ICI and RT has the potential to reshape therapeutic paradigms and improve outcomes for patients.</p>","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The New Paradigm of Simulation-Free Radiotherapy: Practical Recommendations for Successful Clinical Implementation.","authors":"Stephanie Roderick, Shelley Wong, Alannah Kejda, Kylie Grimberg, Toby Lowe, Sarah Bergamin, George Hruby, Jeremy Booth, Thilo Schuler, Thomas Eade","doi":"10.1016/j.prro.2025.05.002","DOIUrl":"https://doi.org/10.1016/j.prro.2025.05.002","url":null,"abstract":"<p><p>Simulation-Free Radiation Therapy (SFRT) is an emerging patient-centred paradigm for palliative radiotherapy. Feasibility and clinical benefits have been demonstrated by several groups, however guidance to overcome technical barriers to adoption is limited. This report describes practical recommendations for; offline preliminary studies, patient selection, image selection and formatting, planning and treatment considerations and quality control. These suggestions aim to enable safe, scalable and effective clinical implementation of SFRT.</p>","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Current and Future State of Radiation Therapy Practice - An Analysis of the Professional Workforce Survey.","authors":"Samantha Skubish, Shaun Caldwell, Sandra Hayden, Melissa Culp, John Culbertson, Jason Paisley, Sheryl Green, Nora Uricchio","doi":"10.1016/j.prro.2025.04.008","DOIUrl":"https://doi.org/10.1016/j.prro.2025.04.008","url":null,"abstract":"<p><strong>Purpose: </strong>In 2023, the American Society of Radiologic Technologists (ASRT) and the American Registry of Radiologic Technologists (ARRT) conducted a Professional Workforce Survey to define current and assess future practices of radiation therapists. The survey focused on the evolving role of radiation therapists, amid staffing constraints and advancements in radiation oncology technologies, exploring clinical duties, knowledge levels, comfort with specific tasks, and the call for advanced practice roles.</p><p><strong>Methods and materials: </strong>In October 2023, the American Registry of Radiologic Technologists ARRT sent 14,822 survey invitations to certified radiation therapists, using a questionnaire based on the ASRT's 2016 pilot survey and current trends in technology and practice¹⁷. By November 2023, 403 responses were received, resulting in a 2.7% response rate. With an estimated 23,000 radiation therapists, the sample size of 403 provides a ±4.8% margin of error at a 95% confidence level.</p><p><strong>Results: </strong>The survey identifies areas where Radiation Therapist's excel with high knowledge, comfort and low supervision while highlighting opportunities to strengthen clinical and technical skills to meet evolving technology and standards. It emphasized the need to define advanced practice roles (APRT) for radiation therapists to improve care delivery, address staffing shortages, and provide career growth. Expanding RT's scope in research and care coordination could help fill gaps, alleviate workforce challenges, and improve outcomes.</p><p><strong>Conclusions: </strong>The findings suggest that the future of radiation therapy practice lies in maximizing the potential of radiation therapists, with additional development needed to define new clinical career pathways and improve patient outcomes. Further research and resources are necessary to establish evidence-based models that leverage radiation therapists' expertise to the level of advanced practice.</p>","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practical Considerations for the Treatment of Primary Renal Cell Carcinoma With SABR.","authors":"James B Yu, David Grew, Erin Sculley, Shankar Siva, Nicholas Hardcastle, Chad Tang, Jinzhong Yang, Minsun Kim, Simon S Lo","doi":"10.1016/j.prro.2025.03.007","DOIUrl":"https://doi.org/10.1016/j.prro.2025.03.007","url":null,"abstract":"","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Favorable Rates of Excellent or Good Cosmetic Outcomes in Patients Treated With Carefully Planned Accelerated Partial Breast Irradiation Delivered Twice Daily or Once Every Other Day.","authors":"Jose G Bazan, Sachin R Jhawar, Sasha Beyer, Erin Healy, Karla Kuhn, Julia R White","doi":"10.1016/j.prro.2025.04.011","DOIUrl":"https://doi.org/10.1016/j.prro.2025.04.011","url":null,"abstract":"","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Acute and Late Toxicities With Daily Versus Every-Other-Day 5-Fraction Partial Breast Radiation Therapy","authors":"Sean M. Parker MD ,&nbsp;Ahmed Halima MD ,&nbsp;Sudha Amarnath MD ,&nbsp;Maria Claudia Moncaliano BS ,&nbsp;Arya Patel BS ,&nbsp;Connor Spera BS ,&nbsp;Elizabeth Obi MD ,&nbsp;Cole Billena MD ,&nbsp;Zahraa Al-Hilli MD, MBA ,&nbsp;Sheen Cherian MD ,&nbsp;Rahul Tendulkar MD ,&nbsp;Chirag Shah MD","doi":"10.1016/j.prro.2025.01.006","DOIUrl":"10.1016/j.prro.2025.01.006","url":null,"abstract":"<div><h3>Purpose</h3><div>Partial breast irradiation (PBI) delivered with intensity modulated radiation therapy over 5 fractions every other day represents an attractive, convenient method of delivering adjuvant radiation therapy for well-selected patients without compromising oncologic or toxicity outcomes. Condensing this regimen to a week of treatment through consecutive daily delivery may further increase patient convenience, though a comparison of toxicities between daily and every other day regimens is limited.</div></div><div><h3>Methods and Materials</h3><div>We retrospectively reviewed 507 patients from an institutional registry undergoing PBI for ductal carcinoma in situ (DCIS) or early-stage breast cancer (T1-2N0/x) from 2015 to 2022. All patients received 30 Gy in 5 fractions with intensity modulated radiation therapy. Acute (toxicity within 90 days of treatment) and chronic toxicity were recorded.</div></div><div><h3>Results</h3><div>Of the 507 patients, 351 were treated every other day, and 159 were treated daily. Median follow-up was longer in the every-other-day group (2.4 vs 1.9 years, <em>P</em> &lt; .001). With regards to acute toxicity, there was slightly reduced grade 1 to 2 dermatitis with daily treatment (39% every other day vs 35% daily, <em>P</em> = .06), while rates of fatigue (18% every other day vs 20% daily, <em>P</em> = .09) were similar. Rates of chronic toxicities were comparable between the two approaches, with no differences in the rates of chronic hyperpigmentation (14% every other day vs 14% daily, <em>P</em> = .97), telangiectasias (1% every other day vs 1% daily, <em>P</em> = .92), mild fibrosis/induration (13% every other day vs 13% daily, <em>P</em> = .91), and lymphedema (0% every other day vs 1% daily, <em>P</em> = .31).</div></div><div><h3>Conclusions</h3><div>Overall, 5-fraction PBI delivered daily appears to be well tolerated with similar acute and chronic toxicity to every other day fractionation.</div></div>","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":"15 3","pages":"Pages e240-e244"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Asymptomatic Pneumomediastinum and Subcutaneous Emphysema on Cone Beam Computed Tomography During Head and Neck Radiation Therapy","authors":"Rojine T. Ariani MD, MS,&nbsp;Vishruth Reddy MD, PhD,&nbsp;Ricky R. Savjani MD, PhD","doi":"10.1016/j.prro.2024.09.001","DOIUrl":"10.1016/j.prro.2024.09.001","url":null,"abstract":"","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":"15 3","pages":"Pages 217-218"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of de Novo Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) and the Role of Radiation Therapy: A Consensus by the Italian Association of Radiotherapy and Clinical Oncology (AIRO)","authors":"Andrea Lancia MD ,&nbsp;Anna Rita Alitto MD ,&nbsp;Giovanni Pappagallo MD, PhD ,&nbsp;Elisa Ciurlia MD ,&nbsp;Giulio Francolini MD ,&nbsp;Rolando D'Angelillo MD, PhD ,&nbsp;Sergio Fersino MD ,&nbsp;Niccolò Giaj Levra MD ,&nbsp;Barbara Alicja Jereczek-Fossa MD, PhD ,&nbsp;Alessandro Magli MD ,&nbsp;Francesco Pasqualetti MD, PhD ,&nbsp;Alessia Reali MD ,&nbsp;Corrado Spatola MD ,&nbsp;Luca Triggiani MD, PhD","doi":"10.1016/j.prro.2024.10.007","DOIUrl":"10.1016/j.prro.2024.10.007","url":null,"abstract":"<div><h3>Purpose</h3><div>Prostate cancer treatments paradigms are in continuous evolution, especially in the metastatic setting. In this context, the Genito-Urinary Group of Italian Association of Radiotherapy and Clinical Oncology aimed to create a consensus on radiation therapy indication in de novo metastatic hormone-sensitive prostate cancer both on primary tumor and metastatic sites.</div></div><div><h3>Methods</h3><div>A panel of experts, involved in clinical management of prostate cancer, through the estimate-talk-estimate method, developed a list of items and correspondent statements on the identified topic.</div></div><div><h3>Results</h3><div>Seven conclusive items were identified with 12 statements about the chosen topic, radiation therapy in metastatic hormone-sensitive prostate cancer on primary tumor and metastatic sites.</div></div><div><h3>Conclusions</h3><div>This consensus might help clinicians in prostate cancer managing in daily clinical practice.</div></div>","PeriodicalId":54245,"journal":{"name":"Practical Radiation Oncology","volume":"15 3","pages":"Pages e286-e294"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}