Journal of the Hong Kong College of Cardiology最新文献_第7页

Early Results of Percutaneous Myocardial Revascularization with Three Dimensional Non-fluoroscopic Electromechanical Mapping - A Novel Revascularization Therapy in Patients with End Stage Coronary Artery Disease 三维非透视机电测绘经皮心肌血运重建术的早期结果——终末期冠状动脉疾病患者的一种新型血运重建术

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-26 DOI: 10.55503/2790-6744.1388

Pui-yin Lee, C. Lau, D. Ho, H. Tse

引用次数: 0

3rd Annual Scientific Meeting Front Matter 第三届科学年会前沿议题

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-25 DOI: 10.55503/2790-6744.1395

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3rd Annual Scientific Meeting Scientific Programme 第三届科学年会科学计划

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-25 DOI: 10.55503/2790-6744.1397

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Blood Coagulation and Heart Disease 凝血和心脏病

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-25 DOI: 10.55503/2790-6744.1384

Y. Kwong

引用次数: 0

Recent Advances in Antithrombin Therapy for Acute Coronary Syndromes 抗凝血酶治疗急性冠状动脉综合征的研究进展

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-25 DOI: 10.55503/2790-6744.1391

Wai-hong Chen, C. Lau

{"title":"Recent Advances in Antithrombin Therapy for Acute Coronary Syndromes","authors":"Wai-hong Chen, C. Lau","doi":"10.55503/2790-6744.1391","DOIUrl":"https://doi.org/10.55503/2790-6744.1391","url":null,"abstract":"CHEN AND LAU : Recent Advances in Antithrombin Therapy for Acute Coronary Syndromes. Unstable angina and acute myocardial infarction are leading causes of hospital admissions worldwide. Following the initiating event of atherosclerotic plaque rupture, activation of the coagulation cascade plays an important role in mediating local thrombosis. Novel antithrombotic agents have recently been developed and applied in clinical practice. The direct antithrombins have the advantage of inhibiting both fluid-phase and clot-bound thrombin. Despite a sound theoretical basis, the prototypical agent hirudin has been demonstrated to be only equivalent to unfractionated heparin as adjunctive therapy to thrombolysis in ST-elevation myocardial infarction. Although showing a better efficacy than unfractionated heparin in unstable angina/non-Q wave myocardial infarction, hirudin causes more major bleeding complications. Low-molecular-weight heparins have the advantages of a better bioavailability, longer half-life and dose-independent clearance, making subcutaneous administration possible and monitoring unnecessary. Enoxaparin has been proven to be superior to unfractionated heparin in two large randomised trials of unstable angina/non-Q wave myocardial infarction while equivalence is demonstrated for other low-molecular-weight heparins. A higher anti-Xa:anti-IIa ratio may explain the varying efficacy. In the near future low-molecular-weight heparins and newer antithrombin agents may replace unfractionated heparin in the management of acute coronary syndromes as ongoing clinical trials further define their roles. (J HK Coll Cardiol 1999;7:109-118)","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46247119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

3rd Annual Scientific Meeting Abstracts 第三届年度科学会议摘要

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-25 DOI: 10.55503/2790-6744.1400

Christina Benishin, Richard Lewanozuk, Jacqueline, Shan

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Guidelines for the Training and Practice of Percutaneous Coronary Interventions 经皮冠状动脉介入治疗的培训和实践指南

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-25 DOI: 10.55503/2790-6744.1393

引用次数: 0

The Utility Of HAS-BLED Score In Predicting The Bleeding Risk Of Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention Receiving Anticoagulation And Dual Anti-platelet Therapy: A Single Center Retrospective Cohort Study 一项单中心回顾性队列研究:经皮冠状动脉介入治疗房颤患者接受抗凝和双重抗血小板治疗后出血风险的预测

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-20 DOI: 10.55503/2790-6744.1211

Luk Yin Cheung Adrian, Chan Chi Lin Jaclyn

{"title":"The Utility Of HAS-BLED Score In Predicting The Bleeding Risk Of Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention Receiving Anticoagulation And Dual Anti-platelet Therapy: A Single Center Retrospective Cohort Study","authors":"Luk Yin Cheung Adrian, Chan Chi Lin Jaclyn","doi":"10.55503/2790-6744.1211","DOIUrl":"https://doi.org/10.55503/2790-6744.1211","url":null,"abstract":"Background : The Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly and Drugs/alcohol (HAS-BLED) score is a validated bleeding risk prediction tool in patients with atrial ﬁ brillation taking oral anticoagulation. Its predictive value in patients with atrial ﬁ brillation undergoing percutaneous coronary intervention receiving combination of anticoagulation and antiplatelet therapy is unknown. This retrospective cohort study sought to validate the accuracy of HAS-BLED score in predicting the bleeding risk in patients with atrial ﬁ brillation who underwent percutaneous coronary intervention receiving both anti-coagulation and dual antiplatelet therapy. Method : We calculated HAS-BLED score in 186 patients with AF undergoing coronary stenting and assessed the incidence of bleeding events de ﬁ ned by the International Society on Thrombosis and Hemostasis (ISTH) bleeding scale. Results : The mean age of the patients was 72. The proportion of male to female was 2.93: 1. Using a HAS-BLED cut off of ≥ 3, a signi ﬁ cantly higher incidence of bleeding was detected in the high HAS-BLED compared to the low HAS-BLED cohort. Such difference of bleeding incidence remained signi ﬁ cant in the triple therapy subgroup whereas it became statistically insigni ﬁ cant in the dual-antiplatelet subgroup. The predictive performance was modest (AUC 0.673, 95% CI, 0.535 e 0.811, p ¼ 0.028). Conclusion : HAS-BLED score is a simple and useful tool to predict bleeding risk in a group of atrial ﬁ brillation patients who require triple therapy after percutaneous coronary intervention.","PeriodicalId":53534,"journal":{"name":"Journal of the Hong Kong College of Cardiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48990027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac Involvement related to COVID-19 Infection and Vaccination in Children and Adolescents – Hong Kong’s Perspective 儿童和青少年新冠肺炎感染和疫苗接种相关的心脏参与——香港的观点

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-20 DOI: 10.55503/2790-6744.1208

S. Tsao, G. Chua, M. Kwan, I. Wong, K. W. To, J. Kwok, Bill H. Chan, J. S. Wong, P. Ip, Y. Lau

引用次数: 0

Effect of low body mass index in outcome of Micra leadless pacemaker implantation 低体重指数对Micra无引线起搏器植入效果的影响

Journal of the Hong Kong College of Cardiology Pub Date : 2022-07-20 DOI: 10.55503/2790-6744.1213

Mark Tsz Kin TAM, Anna Kin Yin Chan, Alex Chi Kin Au, Lily Cheung, Gary Chin Pang Chan, Joseph Yat Sun Chan

引用次数: 1