Obstetrics, Gynaecology and Reproductive Medicine最新文献

Self-assessment questions 自我评估的问题

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-05-01 Epub Date: 2026-03-20 DOI: 10.1016/j.ogrm.2026.02.010

Anna Richmond, Georgina Smart

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Management of malposition and malpresentation in labour 劳动中姿势不当和表现不当的管理

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-05-01 Epub Date: 2026-02-26 DOI: 10.1016/j.ogrm.2026.02.009

Anna K Richmond, Janet R Ashworth

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Overactive bladder syndrome: an updated review of diagnostic and therapeutic modalities 膀胱过度活动综合征：诊断和治疗方式的最新回顾

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-05-01 Epub Date: 2026-02-24 DOI: 10.1016/j.ogrm.2026.02.007

Adebayo Agboola, Aethele Khunda, Victoria Kershaw, Paul Ballard, Sami Shawer

{"title":"Overactive bladder syndrome: an updated review of diagnostic and therapeutic modalities","authors":"Adebayo Agboola, Aethele Khunda, Victoria Kershaw, Paul Ballard, Sami Shawer","doi":"10.1016/j.ogrm.2026.02.007","DOIUrl":"10.1016/j.ogrm.2026.02.007","url":null,"abstract":"<div><div>Overactive bladder (OAB), as defined by the International Continence Society (ICS), is characterised by urinary urgency, usually accompanied by increased daytime frequency and/or nocturia, with urinary incontinence (OAB-wet) or without (OAB-dry), in the absence of urinary tract infection or other obvious pathology. It affects up to 40% of women, with increasing incidence with age. Diagnosis relies on self-reported symptoms and/or bladder diary assessments. Management follows a stepwise approach: first-line interventions include lifestyle modifications, bladder training, and pelvic floor muscle exercises. Pharmacological therapy, such as anticholinergic agents or beta-3 adrenoreceptor agonists, is considered second-line, though caution is advised with anticholinergics due to potential cumulative anticholinergic burden. Approximately 25–40% of women with OAB are refractory to first- and second-line treatments; these patients may benefit from advanced therapies, including intradetrusor Botulinum toxin A, neuromodulation, or reconstructive surgery.</div></div>","PeriodicalId":53410,"journal":{"name":"Obstetrics, Gynaecology and Reproductive Medicine","volume":"36 5","pages":"Pages 133-142"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147828096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gestational trophoblastic disease: clinical presentation and management 妊娠滋养细胞疾病：临床表现和治疗

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-05-01 Epub Date: 2026-03-14 DOI: 10.1016/j.ogrm.2026.02.008

Refaat Youssef, Lesley M McMahon

{"title":"Gestational trophoblastic disease: clinical presentation and management","authors":"Refaat Youssef, Lesley M McMahon","doi":"10.1016/j.ogrm.2026.02.008","DOIUrl":"10.1016/j.ogrm.2026.02.008","url":null,"abstract":"<div><div>Gestational trophoblastic disease (GTD) is a heterogeneous group of early pregnancy disorders encompassing the non-neoplastic partial and complete hydatidiform moles and the malignant conditions of invasive mole, choriocarcinoma, placental site trophoblastic tumour and epithelioid trophoblastic tumour. It also includes other entities such as placental site nodules (PSN) and non-molar abnormal villous lesions. Hydatidiform mole (HM) pregnancies develop due to abnormal proliferation of the villous trophoblast resulting from abnormal conceptions characterized by over-expression of the paternal genome. Patients are often asymptomatic with vaginal bleeding, positive pregnancy test and suggestive ultrasound features continue to be the most common presenting picture of HM. Earlier detection due to advances in ultrasound scanning (US) and first trimester US, facilitates accurate and timely diagnosis and ensures appropriate follow up and management. Cure rate is achieved in 98–100% of cases through effective registration in the well-developed national UK registry, appropriate follow up and treatment programme in one of recognized GTD treatment centres.</div></div>","PeriodicalId":53410,"journal":{"name":"Obstetrics, Gynaecology and Reproductive Medicine","volume":"36 5","pages":"Pages 143-151"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147827992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medicolegal issues in obstetrics 产科的医学法律问题

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-05-01 Epub Date: 2026-02-24 DOI: 10.1016/j.ogrm.2026.02.006

Emma Ferriman

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Self-assessment questions 自我评估的问题

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-04-01 Epub Date: 2026-02-24 DOI: 10.1016/j.ogrm.2026.02.005

Anna Richmond, Georgina Smart

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Managing pelvic organ prolapse with the aid of vaginal pessaries 阴道托的辅助治疗盆腔器官脱垂

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-04-01 Epub Date: 2026-02-19 DOI: 10.1016/j.ogrm.2026.02.002

Georgina Smart, Veenu Tyagi

引用次数: 0

An update on primary dysmenorrhoea: what's new? 原发性痛经的最新进展：有什么新进展？

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-04-01 Epub Date: 2026-02-18 DOI: 10.1016/j.ogrm.2026.02.003

Naimah Raza, Yadava Jeve

{"title":"An update on primary dysmenorrhoea: what's new?","authors":"Naimah Raza, Yadava Jeve","doi":"10.1016/j.ogrm.2026.02.003","DOIUrl":"10.1016/j.ogrm.2026.02.003","url":null,"abstract":"<div><div>Primary dysmenorrhoea is a common gynaecological condition affecting adolescents and women of reproductive age, with substantial impact on quality of life, education, and productivity. It is characterized by cyclical menstrual pain in the absence of pelvic pathology and is primarily driven by excessive prostaglandin-mediated uterine activity, with increasing recognition of central pain sensitization. While first-line pharmacological management with non-steroidal anti-inflammatory drugs and hormonal contraception remains unchanged, recent years have seen a growing evidence base for non-pharmacological and adjunctive interventions. This update summarizes key developments in recent years, including advances in understanding pathophysiology and new data on adjunctive treatment options such as transcutaneous electrical nerve stimulation, acupuncture, exercise, manual therapy, and educational approaches. These modalities support a multimodal, patient-centred approach to management, particularly for women who have an incomplete response to standard treatments or wish to avoid hormonal therapy. Ongoing challenges include heterogeneity of outcomes and limited long-term data, highlighting priorities for future research.</div></div>","PeriodicalId":53410,"journal":{"name":"Obstetrics, Gynaecology and Reproductive Medicine","volume":"36 4","pages":"Pages 115-118"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147661673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal screening for common aneuploidies 常见非整倍体的产前筛查

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-04-01 Epub Date: 2026-02-24 DOI: 10.1016/j.ogrm.2026.02.001

Rupanjali Baranikumar, Farah Siddiqui

{"title":"Prenatal screening for common aneuploidies","authors":"Rupanjali Baranikumar, Farah Siddiqui","doi":"10.1016/j.ogrm.2026.02.001","DOIUrl":"10.1016/j.ogrm.2026.02.001","url":null,"abstract":"<div><div>Screening for trisomy 21 (Down syndrome) screening has been part of clinical practice for over 5 decades. During this time, substantial advances have improved the accuracy, safety, and range of options available to women considering antenatal screening for chromosomal aneuploidy. In the UK, the National Screening Committee has played a pivotal role in setting national standards for screening and guiding improvements in detection rates while reducing false positive results, thereby lowering the number of unnecessary invasive diagnostic procedures such as amniocentesis and chorionic villus sampling, and the associated risk of miscarriage. Non-invasive prenatal testing (NIPT), which analyzes cell-free fetal DNA in maternal plasma, represents the most recent major development in this field. NIPT offers very high sensitivity for common aneuploidies and is now incorporated into the NHS Fetal Anomaly Screening Programme as a contingent test, offered to women who receive a high-chance result from first or second-trimester (combined or quadruple test). This approach is expected to further reduce the number of invasive diagnostic procedures while maintaining current detection rates for trisomy 21, trisomy 18, and trisomy 13.</div></div>","PeriodicalId":53410,"journal":{"name":"Obstetrics, Gynaecology and Reproductive Medicine","volume":"36 4","pages":"Pages 99-104"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147661357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Big Baby Trial: data-informed delivery options 大婴儿试验：数据知情的分娩选择

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2026-04-01 Epub Date: 2026-02-17 DOI: 10.1016/j.ogrm.2026.02.004

Lauren Ewington, Siobhan Quenby

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