植入前基因检测：实用指南

Q3 Medicine

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2025-05-01 DOI:10.1016/j.ogrm.2025.02.004

Karolina Palinska-Rudzka, Raj Mathur

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引用次数: 0

摘要

胚胎植入前基因检测（PGT）是一项结合体外受精（IVF）技术和基因检测的专业技术。本文综述了不同类型的PGT，包括PGT- a， PGT- m和PGT- sr，重点介绍了它们在降低流产率，优化胚胎选择和最小化遗传条件传播方面的作用。此外，它还讨论了胚胎活检的技术方面，与马赛克相关的挑战，伦理考虑和患者咨询。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pre-implantation genetic testing: a practical guide

Pre-implantation genetic testing (PGT) is a specialized technique that combines in vitro fertilization (IVF) technology with genetic testing. This paper provides a comprehensive overview of the different types of PGT, including PGT-A, PGT-M, and PGT-SR, highlighting their roles in reducing miscarriage rates, optimizing embryo selection, and minimizing the transmission of genetic conditions. Additionally, it discusses the technical aspects of embryo biopsy, the challenges associated with mosaicism, and ethical considerations, and patient counselling.

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来源期刊

Obstetrics, Gynaecology and Reproductive Medicine Medicine-Obstetrics and Gynecology

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Obstetrics, Gynaecology and Reproductive Medicine is an authoritative and comprehensive resource that provides all obstetricians, gynaecologists and specialists in reproductive medicine with up-to-date reviews on all aspects of obstetrics and gynaecology. Over a 3-year cycle of 36 issues, the emphasis of the journal is on the clear and concise presentation of information of direct clinical relevance to specialists in the field and candidates studying for MRCOG Part II. Each issue contains review articles on obstetric and gynaecological topics. The journal is invaluable for obstetricians, gynaecologists and reproductive medicine specialists, in their role as trainers of MRCOG candidates and in keeping up to date across the broad span of the subject area.