Global Journal of Transfusion Medicine最新文献_第9页

Can we tweak the golden number of 12.5 gm% hemoglobin for blood donation? 能否调整献血血红蛋白12.5%的黄金数字?

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_70_22

A. Basavarajegowda, Saptarshi Mandal

引用次数: 0

Utilization of blood and blood components in a Tertiary Care Hospital at Bogura, Bangladesh 孟加拉国博古拉三级保健医院血液和血液成分的利用情况

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_41_22

Shuvra Podder, Abdullah Al Masud, N. Poly, Brindaban Biswas, R. Almannie

{"title":"Utilization of blood and blood components in a Tertiary Care Hospital at Bogura, Bangladesh","authors":"Shuvra Podder, Abdullah Al Masud, N. Poly, Brindaban Biswas, R. Almannie","doi":"10.4103/gjtm.gjtm_41_22","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_41_22","url":null,"abstract":"Background and Objectives: Blood and blood components should be transfused cautiously due to potential risks of various transfusion reactions. It is very important for clinicians to be aware of these potential risks. Great progress had been made in the 20th century, by introducing blood component therapy. Now the term “Rational use of blood” came forward. Hence, indiscriminate use of whole blood (WB) should be avoided or minimized. The aim of our article is to demonstrate and evaluate the quantity and pattern of components used in our hospital. Materials and Methods: A retrospective study was carried out in the Department of Transfusion Medicine at a Medical College Hospital from July 2021 to December 2021. Transfusion details were obtained from blood bank records for each patient. Data of all the used blood and components were evaluated and analyzed. Results: Among the male recipients, the majority was of the age group <10 and >50 years, whereas among females, the majority were of age 21–30 and then >50 years. The majority of used blood units were WB (76.48%) followed by red cell concentrate (22.23%) and then platelet concentrate (0.94%). Fresh frozen plasma and cryoprecipitate were not used. The majority of WB was used in patients of trauma or fracture (17.57%), followed by pregnancy-related cases (17.23%), malignancy (10.20%), kidney diseases (7.43%), and others. Conclusion: The use of WB was the most predominant in spite of prevailing facilities for component preparation in our hospital. Our physicians should be oriented to consider and utilize the advantages of using blood components.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"2015 1","pages":"155 - 158"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87865578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Regulations in blood transfusion services: Impetus or impediment? 输血服务监管:推动力还是阻碍?

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_80_22

Aikaj Jindal

引用次数: 1

Storage lesions after irradiation: Comparison between blood stored in citrate phosphate dextrose adenine and saline adenine glucose mannitol 照射后贮藏病变:柠檬酸磷酸葡萄糖腺嘌呤与生理盐水腺嘌呤葡萄糖甘露醇贮藏血液的比较

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_4_22

P. Balasubramanyam, A. Basavarajegowda, N. Hanumanthappa, Anusuya Ram, V. Negi

{"title":"Storage lesions after irradiation: Comparison between blood stored in citrate phosphate dextrose adenine and saline adenine glucose mannitol","authors":"P. Balasubramanyam, A. Basavarajegowda, N. Hanumanthappa, Anusuya Ram, V. Negi","doi":"10.4103/gjtm.gjtm_4_22","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_4_22","url":null,"abstract":"Background and Objectives: Saline adenine glucose mannitol (SAGM) with citrate phosphate dextrose (CPD) or CPD adenine (CPDA) are two common red cell preservatives used in our country. This study analyzed and compared serial biochemical changes on different days of storage in irradiated packed red blood cells stored in CPDA and SAGM solutions. The aim of this study was to see if these changes are influenced by or different, if any, in these two storage solutions. Patients and Methods: Ninety units of RBCs were randomly chosen, with 45 units each collected in CPDA and SAGM, respectively. Nine units each were irradiated by gamma irradiator using cobalt 60 (BI 2000) on days 1, 7, 14, and 21 of their storage, respectively. Nine units were not irradiated and used as controls. All the units were weekly assessed for their plasma levels of potassium, sodium, glucose, lactate dehydrogenase (LDH), and lactate by Clinical Chemistry Auto-analyzer, Beckman Coulter AU680. The values were documented and analyzed by SPSS. Results: Baseline values on day 1 for potassium, lactate, and LDH were similar between SAGM- and CPDA-stored blood bags. Glucose and sodium levels were slightly higher in SAGM bags compared to CPDA. Postirradiation, the changes (increase in K+, Lactate, LDH and decrease in Na+, glucose) were higher in CPDA bags than SAGM bags, and the difference in this trend was not significantly different from that seen in nonirradiated blood bags stored in these two preservative solutions. Conclusion: Storage lesions (biochemical parameters) after irradiation were severe, but paralleled that observed in nonirradiated bags. The storage solution, either SAGM or CPDA, made no difference to these changes.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"77 1","pages":"123 - 128"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80165946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A retrospective audit of red cell serology requisition forms received at a reference Testing Center for work-up 对参考检测中心收到的红细胞血清学申请表进行回顾性审核

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_90_21

P. Pandey, Supriya Kumari, D. Setya

{"title":"A retrospective audit of red cell serology requisition forms received at a reference Testing Center for work-up","authors":"P. Pandey, Supriya Kumari, D. Setya","doi":"10.4103/gjtm.gjtm_90_21","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_90_21","url":null,"abstract":"Background and Objectives: Audits identify areas of problems in immunohematology workup and transfusion practice which can be corrected by the education of medical staff, formulation of guidelines, and algorithms. An audit is a series of simple, direct questions, which when answered and reviewed, tell us whether the laboratory is performing its procedures, activities, and policies correctly. The aim of this study was to analyze immunohematology request forms sent from red cell serology laboratories to our reference testing center (RTC) to ascertain their completeness. Materials and Methods: This was a retrospective, observational study conducted in the department of transfusion medicine at a tertiary-level health-care center from November 2019 to June 2021. We ascertained whether the immunohematology workup forms details were complete, absent, or incomplete. Results: The study was conducted over a period of 20 months, with 264 forms being audited. In this overall total number, almost one-third of 1894 (34.16%) of the immunohematology workup requisition form details were complete and 716 (12.91%) of these entries were incomplete. However, almost half of the overall number of 2934 (52.92%) of the requisitions were absent. Conclusion: From our study, we concluded that an audit of all the RTC requisitions at the point of receiving can be an important tool to detect requisition errors and results of RTC workup. We received a sample for RTC advanced immunohematological testing from all over India. There is a need for the organization of CME and training of staff to increase compliance regarding sending appropriate RTC advanced immunohematological requisitions and samples.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"85 1","pages":"213 - 216"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88927415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical audits – A quality improvement tool in transfusion medicine 临床审计——输血医学质量改进的工具

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_54_22

Monica Gupta, M. Ranapurwala

{"title":"Clinical audits – A quality improvement tool in transfusion medicine","authors":"Monica Gupta, M. Ranapurwala","doi":"10.4103/gjtm.gjtm_54_22","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_54_22","url":null,"abstract":"A clinical audit is a quality improvement process that seeks to improve services and outcomes through a systematic review of care against explicit criteria. It is now a recognized tool for improving clinical quality of care. However, in transfusion medicine, they have been utilized in a limited manner. This review intends to discuss the methodology of carrying out a clinical audit systematically. Clinical audit is not research and focuses on the improvement of ordinary and routine practices. Various methodologies for selecting and prioritizing a good audit topic can be employed. Based on the Donabedian model, process-based audits from donor selection to the actual bedside transfusion could be audited to bring in improvement. Likewise, transfusion processes can be audited based on the dimensions of quality in the context of timeliness, effectiveness, and appropriateness. Prioritization of a topic can be done through a quality impact assessment. The objectives help quantify the aim of the audit, while the standards include criteria that are quantified against targets, based on the current evidence for the best possible care. A snapshot sample (20–50 cases) is sufficient to carry out a clinical audit. Where targets are not met, root-cause analysis and quality improvement tools guide the implementation of changes in transfusion practices. To ensure that change is implemented and internalized, it is necessary to have the entire team and the management on board; communication with all stakeholders is key. Re-audit, after the change has been internalized, is an essential part of all clinical audits. Meticulously planning and proper implementation ensure improvement of the care that transfused patients receive.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"10 1","pages":"115 - 122"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85680685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of double-filtration plasmapheresis in ABO- and human leukocyte antigen-incompatible kidney transplant 双滤过血浆置换在ABO和人白细胞抗原不相容肾移植中的作用

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_7_22

S. Sinha, S. Kabra, S. Mandal, V. Bansal, T. Bhatia, Sumit More, Ranjan Kumar, V. Gupta

{"title":"Role of double-filtration plasmapheresis in ABO- and human leukocyte antigen-incompatible kidney transplant","authors":"S. Sinha, S. Kabra, S. Mandal, V. Bansal, T. Bhatia, Sumit More, Ranjan Kumar, V. Gupta","doi":"10.4103/gjtm.gjtm_7_22","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_7_22","url":null,"abstract":"Kidney transplant has significantly improved the quality of life in end-stage renal disease patients compared to maintenance hemodialysis. Recipients can receive a living-donor or a deceased-donor kidney transplant. However, the presence of donor specific anti human leukocyte antigen (HLA) antibodies or anti A or B antibodies in the recipient makes the transplant incompatible and provokes to cause hyperacute, acute, or chronic rejection. Desensitization which is usually applied before to reduce incompatibility can be achieved by apheresis and preventing donor-specific antibody resynthesis by targeting both T and B cells. Here, we present two such cases transplanted successfully by desensitizing with double-filtration plasmapheresis (DFPP). Case 1 which was a female with high-titer anti-HLA antibody was managed with rituximab, 4 sessions of DFPP, antithymocyte globulin, and posttransplant Tacrolimus (Tac). Case 2 who had both high-titer anti-HLA and anti-A (IgG 1:256) antibody was managed with rituximab, 3 sessions of DFPP, and posttransplant Tac. In both cases, perioperative complications due to DFPP such as bleeding, thrombocytopenia, hypotension, and need of transfusion was minimal. These cases point toward successful application of DFPP in desensitization protocol, leading to successful HLA antibody-incompatible and ABO-incompatible renal transplant with minimal adverse incident and cost.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"75 1","pages":"209 - 212"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86195613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, attitude, practice, and motivation toward blood donation among citizens of Albania 阿尔巴尼亚公民献血的知识、态度、行为和动机

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_22_22

Idris Sula, M. Alreshidi

{"title":"Knowledge, attitude, practice, and motivation toward blood donation among citizens of Albania","authors":"Idris Sula, M. Alreshidi","doi":"10.4103/gjtm.gjtm_22_22","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_22_22","url":null,"abstract":"Background and Objectives: Blood donation is a remarkably safe medical procedure. However, it can easily be affected by attitudes, beliefs, and level of knowledge. A knowledgeable, attitudinal, and practical survey has been used in Albania, to understand and identify (1) The factors that influence blood donation, (2) the factors stopping people from blood donation, (3) the behavior and approach of the people toward blood donation in the future, (4) the knowledge level among donors and nondonors, and (5) misconceptions related to blood donation. Materials and Methods: This search was conducted on online surveys using Google Forms, which were shared through social media platforms such as Facebook, WhatsApp, and Gmail, and a self-administered questionnaire was shared to random people through social media platforms. Results: Of the 858 people answering the questionnaire from Albania, only 32% of the people were blood donors. The motifs that encouraged the people in Albania mostly to donate were to help others in need and save lives and donations for family members. The main reasons preventing people from donation were the fact that they were not asked for and medical reasons. In Albania, 88.6% would donate if called upon. Conclusion: Some of these results reflected an encouraging attitude toward blood donation. Further future planning with emphasis on educational programs and more organizations of donor recruitment campaigns could result in an increase of donations and thus fulfilling the needs of the patients in the country but not only.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"35 1","pages":"129 - 133"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81071490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Syphilis reactivity in blood donors and their response rate – A study from 'Westernized” Western India and the need of the hour for a structured screening methodology 献血者的梅毒反应性及其反应率——一项来自“西方化”的西印度的研究和一种结构化筛查方法的时间需求

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_45_22

Merline Augustine, Ankita Mahambare, M. Mallya, Maria Jose Wiseman Pinto

{"title":"Syphilis reactivity in blood donors and their response rate – A study from 'Westernized” Western India and the need of the hour for a structured screening methodology","authors":"Merline Augustine, Ankita Mahambare, M. Mallya, Maria Jose Wiseman Pinto","doi":"10.4103/gjtm.gjtm_45_22","DOIUrl":"https://doi.org/10.4103/gjtm.gjtm_45_22","url":null,"abstract":"Background and Objectives: An increasing prevalence of sexually transmitted infections especially Syphilis in blood donors may lead to increased donor deferrals and lessen the donor pool. Hence it is the need of the hour to device a structured screening methodology for Syphilis reactive donors. The aim of the study is to estimate the prevalence of syphilis in blood donors and to estimate the response rate of notified blood donors. Patients and Methods: This was a retrospective study, conducted in a Blood Centre (BC) on the blood donors visiting for donation from January 2020 to September 2021. The donors screened positive on chemiluminescence immunoassay were included after informed consent was obtained, and donor demographics and follow-up response rate were analyzed. Frequency and percentages were used to express descriptive statistics and Chi-square was used to test the relationship between categories( p<0.05 considered significant). Results: Out of 26,698 donations during the study period, 133 donors were screened positive for syphilis. 127 (96%) donors consented to postdonation. Out of 127, only 61 were notified regarding the infection and were advised about further followup. 52% of the donors who consented to postdonation counseling were not notified due to erroneous contact details. Out of 46 responders, only 17 underwent further testing. Conclusions: The prevalence rate of syphilis was found to be 0.49%. Among the donors notified, 75% responded back to the BC. Due to social stigma and inadequate knowledge about the disease, often, donors are hesitant to give a reliable exposure history. Adequate education and adapting to a structured screening methodology is the need of the hour to reduce the risk of transfusion-transmitted syphilis.","PeriodicalId":52961,"journal":{"name":"Global Journal of Transfusion Medicine","volume":"60 1","pages":"190 - 195"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84162658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of therapeutic plasma exchange in neuromyelitis optica: A case series 血浆交换治疗在视神经脊髓炎中的作用:一个病例系列

Global Journal of Transfusion Medicine Pub Date : 2022-07-01 DOI: 10.4103/gjtm.gjtm_19_22

R. Parashar, Amit Sharma, Ankit Sharma

引用次数: 0