Journal of Biosafety and Biosecurity最新文献_第10页

Evaluation of animal biosafety webinar series for professionals working in animal facilities across Pakistan during the COVID-19 pandemic 新冠肺炎大流行期间为巴基斯坦各地动物设施工作的专业人员举办的动物生物安全网络研讨会系列评估

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.11.004

Saima Mohsin , Shamsul Arfin Qasmi , Samreen Sarwar

{"title":"Evaluation of animal biosafety webinar series for professionals working in animal facilities across Pakistan during the COVID-19 pandemic","authors":"Saima Mohsin , Shamsul Arfin Qasmi , Samreen Sarwar","doi":"10.1016/j.jobb.2021.11.004","DOIUrl":"10.1016/j.jobb.2021.11.004","url":null,"abstract":"<div><p>Experimental research with animals can help the prevention, cure, and alleviation of human ailments. Animal research facilities are critical for scientific advancement, but they can also pose a higher risk than other biomedical laboratories. Zoonosis, allergic reactions, bites, cuts, and scratches by animals are all substantial concerns that can occur in animal facilities. Furthermore, human error and unexpected animal behavior pose a risk not just to humans, but also to the environment and the animals themselves. The majority of biosafety and biosecurity training programs focus on clinical and biomedical laboratories dealing with human safety factors, with little emphasis on animal biosafety. The current virtual training was designed to improve biosafety and biosecurity capabilities of animal laboratory personnel, researchers, and veterinarians from different regions of Pakistan. The results revealed that understanding was improved regarding triggers for risk assessment in addition to annual and regular reviews (56% to 69%), biosecurity (21% to 50%), decontamination (17% to 35%), safe handling of sharps (21% to 35%), Dual Use Research of Concern (DURC) (17% to 40%), Personal Protective Equipment (PPE) usage by waste handlers (60.9% to 75%), waste management (56% to 85%), animal biosafety levels (40.57% to 45%), and good microbiological practices and procedures (17% to 35%). To bring human and animal laboratories up to the same level in terms of biosafety and biosecurity, it is critical to focus on areas that have been overlooked in the past. Training programs focusing on animal biosafety should be conducted more frequently to strengthen bio risk management systems in animal research facilities.</p></div>","PeriodicalId":52875,"journal":{"name":"Journal of Biosafety and Biosecurity","volume":"4 1","pages":"Pages 12-16"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2588933821000443/pdfft?md5=b589363e1f4eb0a6471cb16ed7cc0e8b&pid=1-s2.0-S2588933821000443-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42833062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent developments and trends of automatic nucleic acid detection systems 核酸自动检测系统的最新发展和趋势

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2022.02.001

Xujun Yuan , Guodong Sui , Dawei Zhang , Min Chen , Wang Zhao

引用次数: 5

Analysis of trends in patent development for coronavirus detection, prevention, and treatment technologies in key countries 重点国家冠状病毒检测和防治技术专利发展趋势分析

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.10.005

Feng Wei , Hong Zhou , Guoqing Gao , Qibin Zheng

{"title":"Analysis of trends in patent development for coronavirus detection, prevention, and treatment technologies in key countries","authors":"Feng Wei , Hong Zhou , Guoqing Gao , Qibin Zheng","doi":"10.1016/j.jobb.2021.10.005","DOIUrl":"10.1016/j.jobb.2021.10.005","url":null,"abstract":"<div><p>Coronavirus causes significant damage to human health and the global economy. In this paper, we undertake patent analysis and data mining to systematically analyze the trend in patent applications for coronavirus detection, prevention, and treatment technologies. Our goals are to determine the correlation between typical coronavirus outbreaks and changes in patent technology applications, and to compare the research and development (R&D) progress, patent layout, and characteristics of major institutions in various countries experiencing coronavirus outbreaks. We find that the United States commenced coronavirus detection and vaccine technology R&D earlier than other countries, as it attached importance to the R&D for treatment technologies from the time of the SARS outbreak and initiated the trend of multi-party R&D, with full technology chain coverage by the government, enterprises, universities, and research institutions. China’s patent applications have grown rapidly in recent years, mainly based on the R&D of research institutions and universities, although it has formed full technology chain coverage. However, the patent quality and technology global layout still need to be improved. This paper reviews the patent development trends of important coronavirus technologies, and proposes that policymakers should establish a long-term mechanism for R&D, pay attention to intellectual property protection, and deepen international technical cooperation to provide a reference for the development and application of coronavirus detection technology, vaccine technology, and treatment technology.</p></div>","PeriodicalId":52875,"journal":{"name":"Journal of Biosafety and Biosecurity","volume":"4 1","pages":"Pages 23-32"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39598861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Application of microneedle-based vaccines in biosecurity 微针疫苗在生物安全中的应用

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2022.04.001

Zhiying Jin , Baohua Zhao , Wei Wan , Yue Li , Xuexin Bai , Chenyi Hu , Jing Wang , Yanwei Li , Wenwen Xin , Lin Kang , Hao Yang , Jinglin Wang , Shan Gao

{"title":"Application of microneedle-based vaccines in biosecurity","authors":"Zhiying Jin , Baohua Zhao , Wei Wan , Yue Li , Xuexin Bai , Chenyi Hu , Jing Wang , Yanwei Li , Wenwen Xin , Lin Kang , Hao Yang , Jinglin Wang , Shan Gao","doi":"10.1016/j.jobb.2022.04.001","DOIUrl":"https://doi.org/10.1016/j.jobb.2022.04.001","url":null,"abstract":"<div><p>Countries must have strong early warning, detection, and response capabilities in the face of the risks and challenges posed by major infectious diseases and bioterrorism threats. Vaccination is one of the most effective means for countries to maintain biosecurity and respond to bioterrorism attacks. Microneedles are emerging as a potential vaccine delivery method with minimal pain, no bleeding, and the ability to be self-administered, doing away with the need for professional health care workers. This last advantage, particularly if combined with room temperature preservation, could have an important role in improving national biosecurity through large-scale, rapid deployment of a biological vaccine. In this review, we summarized the research status of microneedles, including the types, materials, and production technologies of microneedles. Recent progress regarding microneedles in the field of biosecurity is introduced and challenges in its future application are discussed.</p></div>","PeriodicalId":52875,"journal":{"name":"Journal of Biosafety and Biosecurity","volume":"4 1","pages":"Pages 75-83"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S258893382200005X/pdfft?md5=2bc46b3de79d801c5161d5643dd65e6f&pid=1-s2.0-S258893382200005X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137081490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Origin and evolutionary analysis of the SARS-CoV-2 Omicron variant SARS-CoV-2组粒变异的起源和进化分析

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.12.001

Yamin Sun , Wenchao Lin , Wei Dong , Jianguo Xu

引用次数: 73

High-containment facilities and the role they play in global health security 高隔离设施及其在全球卫生安全中的作用

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.11.005

Han Xia , Zhiming Yuan

引用次数: 2

15-Minute nucleic acid test circles strategy in large cities in China 中国大城市15分钟核酸检测圈战略

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2022.06.004

Li Zhenjun, Gao Jiaxuan

引用次数: 2

Development of and prospects for the biological weapons convention 《生物武器公约》的发展和前景

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.11.003

Liang Huigang , Li Menghui , Zhu Xiaoli , Huang Cui , Yuan Zhiming

{"title":"Development of and prospects for the biological weapons convention","authors":"Liang Huigang , Li Menghui , Zhu Xiaoli , Huang Cui , Yuan Zhiming","doi":"10.1016/j.jobb.2021.11.003","DOIUrl":"10.1016/j.jobb.2021.11.003","url":null,"abstract":"<div><p>Biological weapons are used in wars to wound or kill people or animals and destroy crops with pathogenic microorganisms such as bacteria and viruses, as well as toxins and other biologically active substances. These are highly infectious, easily communicable, widely destructive, long-acting, and difficult to prevent and treat. Thus, a major challenge for the international community is preventing the spread of biological weapons throughout the world. The Biological Weapons Convention (BWC) is a multilateral treaty that clearly prohibits the development, production, stockpiling, acquisition and preservation of biological and toxic weapons, as well as the design and delivery of biological warfare agents, except for the purpose of prevention, protection and other peaceful uses. The BWC is, to a certain extent, binding on countries capable of manufacturing biological weapons, and has become a powerful tool enabling the international community to jointly deal with the threats posed by biological weapons. However, its effectiveness has been reduced by the lack of a corresponding verification mechanism. With the rapid development of biotechnology, global biosecurity is faced with new and highly uncertain challenges and threats, which requires the member countries of the BWC to cooperate with, promote, and supervise each other in making constant improvements to the BWC in an effort to maintain global peace and stable development.</p></div>","PeriodicalId":52875,"journal":{"name":"Journal of Biosafety and Biosecurity","volume":"4 1","pages":"Pages 50-53"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2588933821000455/pdfft?md5=c3560005356131467c6a3503b0a0eecf&pid=1-s2.0-S2588933821000455-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54596128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

COVID-19 is a natural infectious disease COVID-19是一种自然传染病

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.11.001

Zhenjun Li , Jiafu Jiang , Yigang Tong , Xiangdong Ruan , Jianguo Xu

引用次数: 1

A One Health strategy for emerging infectious diseases based on the COVID-19 outbreak 基于COVID-19疫情的新发传染病“同一个卫生”战略

Journal of Biosafety and Biosecurity Pub Date : 2022-06-01 DOI: 10.1016/j.jobb.2021.09.003

Qin Wu , Qianlin Li , Jiahai Lu

引用次数: 4