Traditional and Integrative Medicine最新文献

{"title":"Case Reports in Traditional and Integrative Medicine","authors":"Zahra Salehi, M. Farjam, M. H. Hashempur","doi":"10.18502/tim.v7i3.10765","DOIUrl":"https://doi.org/10.18502/tim.v7i3.10765","url":null,"abstract":"The Article Abstract is not available.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46587216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abu Reyhan Biruni (973-1048 CE): The Pioneer in Clarifying the Role of Pharmacy in Medical Practice","authors":"Mahya Roohnavaz, H. Tekiner, Mohammad Reza Shams Ardakani, A. Zargaran","doi":"10.18502/tim.v7i3.10777","DOIUrl":"https://doi.org/10.18502/tim.v7i3.10777","url":null,"abstract":"Abu Reyhan Biruni (973-1048 CE) was a Persian polymath in medieval era. He had more than 100 books and treatises on different subjects like astronomy, culture, history, mathematics and pharmacy. In medical sciences, he was one of the first persons who introduced pharmacy as a separated field from medicine. He was pioneer to define pharmacy and pharmacist similar to current definitions. It was one of the earliest definitions of pharmacy. Biruni can be introduced as a pharmacist, nor physician. He also had a book on pharmacy, Al-Saydana fi al-Tibb (Pharmacy in Medicine). This book is one of the most important works on pharmacy in medieval era. He clarifies the role of pharmacists to serve pharmaceutical services to the patients. It shows the importance of pharmacy as an independent field of medical sciences in Persia and Islamic civilization about a thousand years ago.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41738348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical Approach to the Hotness and Coldness of Mizaj in Persian Medicine: A Cross-Sectional Survey in the Healthy Population","authors":"Seyyed Ali Mozaffarpur, M. Azizi, H. Parsian, M. Mojahedi, H. Shirafkan","doi":"10.18502/tim.v7i3.10766","DOIUrl":"https://doi.org/10.18502/tim.v7i3.10766","url":null,"abstract":"An individualized viewpoint in Persian Medicine is introduced with the concept of Mizaj (temperament). Accordingly, every individual is placed in a unique point among a spectrum ranging from extreme hotness to extreme coldness. The whole-body Mizaj is mainly determined by three organs of heart, brain, and liver. This study investigates the relationship between whole-body and three main organ Mizajes with some hormonal and biochemical factors. In 324 healthy volunteers between the ages of 20 and 40, whole-body Mizaj and Mizajes of heart, brain, and liver were determined in two sessions with an expert panel method. Any disagreement between experts and the moderate diagnosis was excluded. Finally, 72 healthy volunteers (including 40 hot Mizaj individuals and 32 cold Mizaj) entered the second phase. In this phase, some hormonal and biochemical factors were evaluated. In whole-body Mizaj, FBS, Hgb, Hct, MCHC, WBC, and Monocytes, were higher in people with hot Mizaj than cold Mizaj. Besides, relating to the Mizaj of the liver, FBS, cortisol, TG, Hgb, Hct, MCH, MCHC in hot Mizaj were higher than cold Mizaj. Also, in the heart, MCV and MCH were higher in hot individuals and in the brain FBS, Hgb, Hct, MCV, MCH, lymphocytes were significantly higher in hot Mizaj. It seems that FBS and Hgb as the factors involved in metabolism have the most important role in the whole-body Mizaj. Also, the association between cortisol with the hotness of the liver can be suggested by increasing sympathetic activity as one of the hotness/coldness theories. \u0000 ","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45471451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pro-Sexual Effects of Aqueous and Methanol Extracts of Phyllanthus muellerianus (Kuntze) Exell (Phyllanthaceae) on a Model of Low Sexual Desire Disorder in Female Rats","authors":"E. Ngadjui, Henderson Herris Kar, Ngombeu Zeugang, François Xavier Kemka Nguimatio, M. Wankeu-Nya, G. B. Bonsou Fozin, Aime Cesaire Momo Tetsatsi, P. Watcho","doi":"10.18502/tim.v7i2.9923","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9923","url":null,"abstract":"Low sexual desire disorder is a recurrent deficiency in desire for sexual activity which impairs lifestyle. It is a frequent problem in women with limited therapeutic options. Phyllanthus muellerianus (Kuntze) Exell is a plant used by traditional healers to boost libido in women. This study aimed at evaluating the aphrodisiac properties of root barks extracts of this plant on a model of Low Sexual Desire Disorder (LSDD) in female rats. Low sexual desire was induced by ovariectomy plus low steroid hormones supplementations. Thirty ovariectomized rats were treated for 21 days with either distilled water, aqueous or methanol extracts (60 or 372 mg/kg) of P. muellerianus. All animals were supplemented with a low dose of 17β-estradiol and progesterone prior to sexual behavior test. Sexual behavior test was performed each week by pairing each female rat with a sexually experienced male. Sexual motivation (approach, ear wiggling, hops and darts, anogenital presentation and aggressive behavior frequency) and sexual receptivity parameters (lordosis frequency and quotient) were recorded. At the end of treatments, animals were sacrificed, uteri and vagina collected, weighed and conserved for total uterine proteins assay and histology. LSDD was characterized by significant inhibition of sexual motivation parameters and lordosis frequency compared to a normal control. Moreover, poor reproductive tissues growth characterized by low total uterine proteins, uterine wet weight and uterine epithelia size was noted in LSDD group compared to normal control. Interestingly, plant extracts significantly improved sexual motivation parameters (p < 0.05-0.001) compared to LSDD group. In addition, moderate reproductive tissues growth was noted in plant treated groups as confirmed by amelioration of uterine cell integrity. Present results show that P. muellerianus exhibits pro-sexual effects through amelioration of sexual motivation and reproductive tissues growth on a model of LSDD.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47221349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Carthamus tinctorius L. (Safflower) on National Institute of Health Stroke Scale Scores of Ischemic Stroke Patients: A Pilot Clinical Trial","authors":"M. Yousefi, P. Sasannezhad, H. Rakhshande, H. Doosti, A. Saki, Zahra Baghestani Kouzegar, Hamideh Ahmadi, Elahe Delshad","doi":"10.18502/tim.v7i2.9922","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9922","url":null,"abstract":"Experiencing complications within the first two weeks after stroke leads to a high risk of mortality and length of hospitalization. The present pilot study was intended to investigate the hypothesis that adult patients treated with safflower or not would present with fewer neurological complications following 15 days. In a randomized controlled trial, subjects diagnosed with ischemic cerebrovascular accident (CVA) based on focal neurological findings on brain imaging who met the inclusion criteria of our study were recruited from Ghaem Hospital, Mashhad, Iran, between 2016 and 2017. Thirty-six patients were included in the survey and randomly allocated into treatment (A) and control (B) groups. An oral syrup of safflower extract and nasal drop of safflower oil were additionally prescribed for group A. Group B only received a standard anti-ischemic regimen. The primary outcome measure was the National Institutes of Health Stroke Scale score (NIHSS) over 15 days. Safflower treatment led to a notably higher mean difference in the NIHSS score between the baseline score and 15-day post-treatment score in group A in comparison to group B (p < 0.001). However, adjustment for covariates (age, gender, and baseline measures) showed no significant reduction in neurological status between them (p = 0.340). There was a statistically significant difference in neurological symptom scores between the groups (p = 0.044). Based on this pilot study, adjuvant treatment with safflower in addition to the standard anti-ischemic regimen can be more effective than individual conventional drugs for treating ischemic CVA among adults.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49315846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herbal Medications to Manage Insomnia: An Overview of Clinical Trials Using Herbal Treatment for Insomnia","authors":"M. Ranjbar, Mohammad Mazaheri, M. Ansaripour, M. Babaeian, Atefeh Jalali, M. Zarshenas","doi":"10.18502/tim.v7i2.9928","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9928","url":null,"abstract":"Insomnia is one of the most prevalent sleep disorders worldwide which significantly affects the quality of life. Pharmacological and non-pharmacological approaches have been applied in managing insomnia. The risk of tolerance and dependence on conventional medications and their other side effects leads the surveys to complementary and alternative medicine. This overview aimed to compile the clinical trials on herbal remedies in managing insomnia for facilitating future studies on medicinal plant in this issue. The keywords “Medicinal plant”, “Herbal medicine” in combination with “Hypnotic and sedative”, “Insomnia” or “Sleep” were searched through PubMed, Google Scholar, and Scopus electronic databases from 1st January 2000 to 31st August 2020. Then, all clinical trials focusing on the efficacy of medicinal plants on insomnia were collected. Based on the inclusion and exclusion criteria, 36 articles were selected, included 16 medicinal plants (23 studies) as a single herb and 13 polyherbal formulations. The most prevalent route of administration among these trials was oral. Matricaria chamomilla L., Valeriana officinalis L., Viola odorata L., and Passiflora incarnata L. were among the most prevalent effective herbal medicines on insomnia. Also, the modulation of the GABAergic system was the most common target of these medicinal plants. Herbal remedies can be introduced as safe and effective alternatives for conventional medications in managing insomnia. The popular herbal medicines, such as M. chamomilla, V. officinalis, V. odorata, are suitable for further therapeutic development. Other cited medicinal plants in this review can be more investigated in improvement of sleep.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45976491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Compound Honey Syrup on Clinical Manifestation of the Adult Asthma Patients: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial","authors":"Shahpar Kaveh, Narges Kaveh, K. Agin, S. Sadr, R. Choopani, A. Karimi Rouzbahani","doi":"10.18502/tim.v7i2.9920","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9920","url":null,"abstract":"Asthma is a chronic inflammatory disease of the respiratory tract which includes inflammation and obstruction of the airways. Modern medical treatment has side effects in addition to therapeutic effects. According to the high incidence of asthma, the use of complementary therapies has risen, such as compound honey syrup in Traditional Persian medicine and Integrative medicine as a treatment for asthma. Therefore, the aim of this study was to evaluate the effect of compound honey syrup in improving the clinical symptoms of adult asthma referred to Loghman hospital. This randomized, double-blinded, controlled trial was performed on 80 patients with asthma symptoms. Patients were divided into two groups of 40 and the study was conducted for 12 weeks. The intervention group received classic asthma treatment and compound honey syrup. The control group also received classic asthma treatments plus placebo. The questionnaire was done by individuals at the beginning and end of the study. At the end of study some factors like night symptoms, morning symptoms, activity limitation, shortness of breath, wheezing, and use of Short Acting Beta Agonist (SABA) were significantly decreased in both groups, but it had a greater extent in the intervention group than in the control group. Difference in total scores and some items of Asthma Control Test (ACT) were significant between groups (P < 0.05). No serious adverse effects were observed in any of the groups. The results of this study demonstrate that compound honey syrup can be a safe and effective drug for the treatment of asthma in adults.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43313729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Awareness, Attitude and Performance of Surgical Team about Medicinal Plants Use by Candidate Patients for Surgery","authors":"Mehdi Ghasemzadeh Bariki, E. Nasiri, S. Barat, Hooshang Akbari","doi":"10.18502/tim.v7i2.9921","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9921","url":null,"abstract":"Due to the increasing application of traditional and complementary medicine methods as well as medicinal herbs and given the drug interactions during surgery, the goal of this study was to determine the awareness, attitude and performance of surgical team regarding the use of herbs by surgical candidates. In this cross-sectional descriptive study, members of surgery and anesthesia team completed a data collection form, which included personal information and specialized questions (10 awareness, 9 attitudes, and 9 performance questions). The score for each awareness question was 0-2, which was 1-5 for attitude and performance questions, respectively. Quantitative data were reported with mean ±SD, and qualitative data were reported as frequency percentage. Quantitative variables were analyzed by Mann-Whitney and Kruskal-Wallis tests, and qualitative variables were assessed using Chi-square test. Among 185 participants, there were 99 women (53.6%). 31.4% of participants were specialists or assistants, 87.6% of them had moderate attitude, 82.3% showed poor performance and 82.2% poor awareness. The level of awareness was not significant in terms of specialization but that of attitude (p < 0.001) and performance (p < 0.019) was significant. Considering the growing trend of medicinal plants’ consumption in people, and given the moderate attitude, as well as poor awareness and performance of surgical team members toward medicinal plants, increasing knowledge level, prevention of drug interactions and potential side effects of medicinal plants together with training planning are essential for surgical team members to increase patient safety.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42597117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of In vitro Wound Healing Activity of Polygonatum orientale Desf. Rhizome","authors":"Ghazal Hashemi, H. Adhami, M. Rahimifard, M. Baeeri, P. Sarkhail","doi":"10.18502/tim.v7i2.9925","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9925","url":null,"abstract":"In this study, we carried out a bioassay-guided fractionation of the most active extract Polygonatum orientale Desf. rhizome, in order to isolate and identify the fraction/s or compound/s responsible for wound healing activity. The wound healing process considered via scratch wound assay on NIH-3T3 fibroblasts. The results showed that the methanol extract and its fractions A5 and A6 showed excellent wound healing effect and were rich of bioactive glycoside compounds. Fraction A6 was selected for further fractionation and two sub-fractions B5 and B6 showed acceptable wound healing on fibroblasts. B5-P (sucrose) and B6-P were isolated as two active compounds from theses fractions that significantly reduced wound area, without any toxicity at very low concentrations (50-200 ng/mL). These results supported the traditional use of P. orientale rhizome for wounds treatment and showed that the accelerated wound healing activity of the rhizome is due to the presence of bioactive polar compounds.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41994482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fine-Humor Producing Materia Medica in Persian Medicine","authors":"Yahya Zeinalpour Fattahi, F. Fadaei, A. Asghari, Ayeh Naghizadeh, M. Karimi","doi":"10.18502/tim.v7i2.9927","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9927","url":null,"abstract":"According to Persian Medicine (PM), humors that can replace the consumed body compounds, while contributing to health maintenance, is called ‘fine humor’ (khelt-e saleh). However, a limited number of foods and beverages have been mentioned as the producers of fine humor. These substances are particularly important in maintaining health in vulnerable populations including pregnant women, lactating mothers, the elderly, infants and children. They also play an important role in certain treatment plans during illness and injury and after recovery. The present study was designed to investigate properties of fine-humor producing materia medica, as described by PM resources. Based on the search performed in PM textbooks, 63 substances were found to have this property. The most frequent Mizaj types were hot-wet (33.34%), hot-dry (19.05%), and cold-wet (17.47%). The highest organ tropism belonged to kidneys and bladder, brain, liver, sex organs, stomach and lungs respectively. Examining drug actions indicated obesogenous (53.97%), enhancing sperm production and sexual potency (42.86%), laxative (39.69%), and tonic (33.34%) actions to be the most prevalent effects of these substances in the body. By integrating these substances into diets, health promotion for children, the elderly, and mothers during nursing and pregnancy may be achieved. Additionally, patients can benefit from a fine-humor producing nutrition both for 1) prevention of chronic diseases and 2) during disease recovery, acute phases of illness, anemia, and metabolic illnesses. Further studies are recommended to analyze the components and nutritional value, and the use of PM capability in culinary medicine.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46849333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}