Traditional and Integrative Medicine最新文献_第10页

The Effect of Zataria multiflora Boiss. Mouthwash on the Oral Microbial Load in Patients under Mechanical Ventilation: A Randomized Controlled Trial 多花扎莉的药效研究。漱口水对机械通气患者口腔微生物负荷的影响:一项随机对照试验

Traditional and Integrative Medicine Pub Date : 2022-06-29 DOI: 10.18502/tim.v7i2.9919

Z. Gholami, M. Dianati, Mahboobeh Maghami, M. Afazel, Ismail Azizi-fini

{"title":"The Effect of Zataria multiflora Boiss. Mouthwash on the Oral Microbial Load in Patients under Mechanical Ventilation: A Randomized Controlled Trial","authors":"Z. Gholami, M. Dianati, Mahboobeh Maghami, M. Afazel, Ismail Azizi-fini","doi":"10.18502/tim.v7i2.9919","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9919","url":null,"abstract":"This study aimed to examine the effect of Zataria multiflora Boiss. mouthwash on the microbial load of the oral cavity in patients under mechanical ventilation. This randomized controlled trial was conducted in 2019 on patients under mechanical ventilation. Sampling was performed using the consecutive method. Using a block randomization method, 90 patients were allocated to three equal groups of 30 to receive mouth care using chlorhexidine, Z. multiflora, or normal saline. Mouthwash was used three times a day for a week. Eight hours before and after the intervention, sterile samples of saliva were collected and cultured in the laboratory. Chi-square, Fisher’s exact test, paired t and McNemar’s tests, and analysis of variance were used to analyze the data. After the interventions, a significant difference in the microbial load was found between the three groups (P < 0.021). The Tukey post hoc test showed a significant difference between the group treated with Z. multiflora and those who received chlorhexidine (P value = 0.016). The frequency of patients with positive cultures was lower in the group treated with Z. multiflora and the differences were statistically significant in terms of Acinetobacter (P = 0.01) and Klebsiella pneumonia (P = 0.02). Z. multiflora mouthwash was effective in decreasing the microbial load of the oral cavity. This mouthwash can be used to reduce the microbial load of the oral cavity in patients under mechanical ventilation and reduce the risk of ventilator-associated pneumonia.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48079283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective Effect of Nanoparticles of Oleoresin of Pistacia atlantica var. mutica Against Acetic Acid-Induced Ulcerative Colitis in Rats 木黄连木油树脂纳米颗粒对醋酸致大鼠溃疡性结肠炎的保护作用

Traditional and Integrative Medicine Pub Date : 2022-06-28 DOI: 10.18502/tim.v7i2.9915

Maryam Naseri, Hanieh Delfani, S. Mirzaeei, G. Bahrami, M. Farzaei, Pardis Mohammadi Pour

{"title":"Protective Effect of Nanoparticles of Oleoresin of Pistacia atlantica var. mutica Against Acetic Acid-Induced Ulcerative Colitis in Rats","authors":"Maryam Naseri, Hanieh Delfani, S. Mirzaeei, G. Bahrami, M. Farzaei, Pardis Mohammadi Pour","doi":"10.18502/tim.v7i2.9915","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9915","url":null,"abstract":"Dying Various therapeutic activities of Pistacia atlantica var. mutica such as hypoglycemic, antioxidant and anti-inflam matory activity were shown by several studies. Regarding these therapeutic activities, and due to advantages of nanoparticles for drug delivery systems, the anti-colitic effects of P. atlantica var. mutica oleoresin nanoparticles were studied in acetic acid-induced ulcerative colitis in rats. Nanoparticles were synthesized by using ethanol and acetone as solvent. Nano precipitation method was also used for nanoparticles synthesis. P. atlantica oleoresin was orally administered to acetic acid-induced colitis rats at the doses of 50, 100 and 200 mg/kg. Then rats were killed and their colons were dissected away for histopathological and macroscopic tests. Statistical results showed homogeneity and uniformity in size and size distribution of fabricated nanoparticles. Proposed models for size and size distribution of nanoparticles were also adequate (P value < 0.05). All doses of nanoparticles of P. atlantica oleoresin significantly reduced macroscopic damage score. The microscopic study also showed anti-colitic activities of P. atlantica oleoresin nanoparticles. Administration of 200 mg/kg of fabricated nanoparticles showed better anti-inflammatory and healing effects compared to other doses. Our results showed that nanoparticles of P. atlantica var. mutica oleoresin might be an effective agent to treat ulcerative colitis disease, due to the therapeutic activities of the plant and desirable properties of fabricated nanoparticles. Therefore, nanoparticles of P. atlantica var. mutica oleoresin might provide an alternative drug for colonic inflammation.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45524037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Effects of Ear Acupressure on Back Pain after Coronary Angiography: A Randomized Controlled Trial 耳指压对冠状动脉造影后背部疼痛的影响:一项随机对照试验

Traditional and Integrative Medicine Pub Date : 2022-06-28 DOI: 10.18502/tim.v7i2.9917

S. Vagharseyyedin, Mojgan Kardan, H. Rahimi, H. B. Bahrami Taghanaki, N. Azdaki

{"title":"The Effects of Ear Acupressure on Back Pain after Coronary Angiography: A Randomized Controlled Trial","authors":"S. Vagharseyyedin, Mojgan Kardan, H. Rahimi, H. B. Bahrami Taghanaki, N. Azdaki","doi":"10.18502/tim.v7i2.9917","DOIUrl":"https://doi.org/10.18502/tim.v7i2.9917","url":null,"abstract":"Back pain is a common complaint seen in patients after coronary angiography. This study investigated the efficacy of ear acupressure for reduction of back pain in patients after coronary angiography. In this trial, 120 patients recruited from a post-angiography ward were allocated to an ear acupressure or a control group. Pain assessment in intervention group was performed immediately after participants entered post- coronary angiography ward (T0), twenty minutes after entering the ward (T1), and two, four, and six hours after the intervention (T2–T4). Pain in control group was assessed at the times similar to intervention group. Data were analyzed using the SPSS software (v. 19) by Chi-square, Fisher’s exact, independent t tests, Friedman test, Wilcoxon signed-rank, and Mann-Whitney U test. Final data analysis was done on the data gathered from 58 participants in the control group and 59 in the ear acupressure group. The pain intensity at T1–T4 for patients in the control group was significantly higher than T0 (P < 0.001), while patients in the ear acupressure group reported that pain intensity at T2–T4 was significantly higher than T0 for them (P < 0.001). Only at T1 and T2, pain intensity in the ear acupressure group was significantly less compared to the control group (P < 0.05). Ear acupressure in this study was effective to some extent in reducing back pain after coronary angiography. Future studies can be designed to examine the effects of ear acupressure using different ear acupressure points on the back pain after coronary angiography.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47245299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Overview of Sang-e-Surma (Antimony Sulphide or Lead Sulphide): A Mineral Origin Unani Drug Sang-e-Surma（硫化锑或硫化铅）：一种矿物来源的Unani药物综述

Traditional and Integrative Medicine Pub Date : 2022-03-30 DOI: 10.18502/tim.v7i1.9069

M. -, M. Azhar, Sofia Naushin, Mohd Urooj, Gulam Mohammed Husain

引用次数: 0

Ethnopharmacological Survey of Plants Used for the Treatment of Female Sexual Dysfunction and Infertility in Ilorin, Nigeria 尼日利亚伊洛林治疗女性性功能障碍和不孕症植物的民族药理学调查

Traditional and Integrative Medicine Pub Date : 2022-03-30 DOI: 10.18502/tim.v7i1.9068

Quadri Olaide Nurudeen, S. S. Salimon, M. Falana, M. Yakubu, M. A. Akanji

{"title":"Ethnopharmacological Survey of Plants Used for the Treatment of Female Sexual Dysfunction and Infertility in Ilorin, Nigeria","authors":"Quadri Olaide Nurudeen, S. S. Salimon, M. Falana, M. Yakubu, M. A. Akanji","doi":"10.18502/tim.v7i1.9068","DOIUrl":"https://doi.org/10.18502/tim.v7i1.9068","url":null,"abstract":"Over generations, several indigenous knowledge on the use of medicinal plants have been lost due to a lack of interest of the upcoming generation and reluctancy of the older generations to pass on their knowledge. This survey was set about to preserve and share the knowledge of the Ilorin Emirate Clan in the management of female sexual dysfunction and infertility (FSDI). The survey was conducted across three major markets (Shao, Jimba-Oja and Oke-Oyi) and ethnobotanical data on medicinal plants, mode of preparation, route of administration and demographic information were collected from volunteers using a semi-structured questionnaire, oral or virtual interviews. A total of 47 plant species belonging to 28 families were identified from 85 willing respondents. Phyllanthus amarus Schumach. & Thonn. was the most frequently cited plant with a citation frequency of 31.76% and a fidelity level of 57.75% whereas Xylopia aethiopica (Dunal) A.Rich. was the least cited plant with a citation frequency of 1.18% and a fidelity level of 1.12%. The highest informant consensus factor computed for Shao market, Jimba-Oja and Oke-Oyi were 0.93, 0.57 and 0.84 for P. amarus, Sarcocephalus latifolius (Sm.) E.A.Bruce and Cassia fistula L., respectively. This study provides a comprehensive insight into the medicinal plants in our society that are of importance in the management of female sexual dysfunction and infertility. The data collected would promote the conservation of invaluable indigenous knowledge and highlight a broad selection of medicinal plants that could be subjected to further pharmacological and clinical investigation for their potential role in the treatment of FSDI.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46492146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effectiveness of Cupping in Iranian Researches: A Systematic Review of Animal and Human Studies 拔罐在伊朗研究中的有效性:动物和人类研究的系统综述

Traditional and Integrative Medicine Pub Date : 2022-03-30 DOI: 10.18502/tim.v7i1.9070

Hoorieh Mohammadi kenari, Gholamreza Kordafshari, M. Moghimi

引用次数: 1

Formulation Development, Characterization and Antimicrobial Activity Evaluation of Sugar-Based and Sugar-Free Syrup Prepared with the Ingredients of Jushanda-Nazla 菊芋无糖糖浆的研制、表征及抗菌活性评价

Traditional and Integrative Medicine Pub Date : 2022-03-30 DOI: 10.18502/tim.v7i1.9067

Syed Zubair Ali, Khaleequr Rahman, A. Sultana

{"title":"Formulation Development, Characterization and Antimicrobial Activity Evaluation of Sugar-Based and Sugar-Free Syrup Prepared with the Ingredients of Jushanda-Nazla","authors":"Syed Zubair Ali, Khaleequr Rahman, A. Sultana","doi":"10.18502/tim.v7i1.9067","DOIUrl":"https://doi.org/10.18502/tim.v7i1.9067","url":null,"abstract":"Jushanda (decoction), often used in traditional medicine, has many drawbacks like disagreeable taste, bulky dose, cumbersome preparation, and short stability. Therefore, in the present study, jushanda nazla (JN) was modified and optimized into a sugar-based (SBS) and sugar-free (SFS) syrup dosage form and evaluated for various physicochemical parameters, microbial contaminations and antimicrobial activities. JN was concentrated and reduced to minimum quantity by heating and twelve batches of SBS and five batches of SFS were prepared for optimization. Out of these, the best batch of SBS and SFS were selected based on consistency and minimum bulk. The best batches were further evaluated for the physicochemical parameter, microbial and heavy metal contamination. The finished products were also evaluated for antimicrobial activity against selected microbes. SBS was optimized with 170 mL JN reduced to 50 mL, sugar 40% (w/v) and consistency of one wire. SFS was optimized with 170 mL JN reduced to 30 mL, and 96 mg of aspartame. Organoleptic characters, ash value, viscosity, specific gravity and pH of finished products were satisfactory. The concentration of total phenolic, flavonoid, tannin, alkaloid and glycyrrhizin and chlorogenic acid were comparative in JN, SBS and SFS. SBS and SFS passed the WHO guideline for microbial and heavy metal contamination. Finished products showed significant antimicrobial activity against Streptococcus pyogenes, Streptococcus pneumoniae, Haemophilus influenzae and Salmonella. Analytical data of SBS and SFS showed significant optimistic results hence, generated data can be used for future reference. However, developed formulations should be further evaluated for their stability, safety and clinical efficacy.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46948605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ideal Lifestyle to Have Healthy Lungs: Persian Medicine Viewpoint 拥有健康肺部的理想生活方式：波斯医学观点

Traditional and Integrative Medicine Pub Date : 2022-03-30 DOI: 10.18502/tim.v7i1.9071

A. Abdolahinia, M. Naseri, S. Tahmasbi, P. Adimi, M. Sadr, A. Velayati

引用次数: 0

Comparison of Supercritical Fluid Extraction and Ultrasound-Assisted Extraction of Corchorus Olitorius L. and Evaluation of Their Antioxidant Properties and Identification of Compounds Using LC-ESI-MS 超临界流体萃取法与超声辅助萃取法的比较、抗氧化性能评价及LC-ESI-MS鉴定

Traditional and Integrative Medicine Pub Date : 2022-03-29 DOI: 10.18502/tim.v7i1.9065

Hanieh Nasrollahi, M. Karimi, F. Raofie

{"title":"Comparison of Supercritical Fluid Extraction and Ultrasound-Assisted Extraction of Corchorus Olitorius L. and Evaluation of Their Antioxidant Properties and Identification of Compounds Using LC-ESI-MS","authors":"Hanieh Nasrollahi, M. Karimi, F. Raofie","doi":"10.18502/tim.v7i1.9065","DOIUrl":"https://doi.org/10.18502/tim.v7i1.9065","url":null,"abstract":"Corchorus olitorius L. is a medicinal herb with anti-inflammatory, laxative, and tonic properties, which is effective on the treatment of cancer and tumors. In this study, the extraction efficiency of supercritical fluid extraction (SFE) and ultrasound-assisted extraction (UAE) of C. olitorius as well as their antioxidant activities were investigated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical. For this purpose, central composite block cube star and central composite design were employed to determine the optimal conditions. Thereafter, the qualification analysis of the effective ingredients of C. olitorius was done by LC-ESI-MS in negative mode. The results of LC-MS showed that C. olitorius includes phenolic and flavonoid compounds such as caffeic acid, p-coumaric acid, trans-ferulic acid, quercetin, naringenin, cirsiliol, cirsilineol, quercetrin, and naringin. Moreover, the SFE efficiency of extraction and IC50 value was obtained 4.25% and 1208.99 µg/mL, respectively. Also, the UAE efficiency of extraction and IC50 of antioxidant activity was obtained as 15.29% and 994.284 µg/mL, respectively. These results confirmed that the efficiencies of extraction and antioxidant activity of UAE were higher than that of SFE; however, the SFE is an environmentally friendly method and consumed less organic solvent.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43994205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Treatment Role of Terpenoid Fraction of Perovskia abrotanoides Kar. on Zoonotic Cutaneous Leishmaniasis in Animal Model Perovskia大麻素Kar萜类部分的治疗作用。动物模型中人畜共患皮肤利什曼病的研究

Traditional and Integrative Medicine Pub Date : 2022-03-29 DOI: 10.18502/tim.v7i1.9064

Masoud Sadeghi Dinani, J. Rezapour, S. Soleimanifard

{"title":"Treatment Role of Terpenoid Fraction of Perovskia abrotanoides Kar. on Zoonotic Cutaneous Leishmaniasis in Animal Model","authors":"Masoud Sadeghi Dinani, J. Rezapour, S. Soleimanifard","doi":"10.18502/tim.v7i1.9064","DOIUrl":"https://doi.org/10.18502/tim.v7i1.9064","url":null,"abstract":"Leishmaniasis is one of the infectious diseases in tropical countries that is seen as cutaneous, mucocutaneous and visceral forms. Due to the side effects, costs and effectiveness of anti-leishmaniasis drugs, many clinical trials have been conducted on the importance of plant-based substances against leishmaniasis. Therefore, the following study was performed to evaluate the therapeutic effects of Perovskia abrotanoides Kar. terpenoid fraction on cutaneous leishmaniasis in Balb/c mice. The ethanol: water (80:20) extract of the plant flowers was fractionated by Medium Pressure Liquid Chromatography using RP-18 column. The terpenoid-rich fraction was detected by TLC and HNMR analyses and evaluated for healing effects on cutaneous leishmaniasis in mice with concentrations of 0.8%, 1.6% and 3.2 µg/mL. The effect of that was evaluated using ANOVA statistical tests. The results indicate that terpenoid of P. abrotanoides in 3.2% concentration is effective in treating cutaneous leishmaniasis in mice and also increases the lifespan and decreases the parasite burden of infected mice. According to this result, it is suggested that the effectiveness of this extract on the treatment of cutaneous leishmaniasis to be evaluated as a clinical trial in humans.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41809498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0