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Evaluation of blood transfusion practice in obstetrics and gynaecology at a tertiary hospital in Port Harcourt, Nigeria 对尼日利亚哈科特港一家三级医院妇产科输血实践的评价
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_130_22
Simeon C. Amadi, P. Awoyesuku, H. Omunakwe, Linda Dublin-Green, U. Ocheche, Chinweowa Ohaka
{"title":"Evaluation of blood transfusion practice in obstetrics and gynaecology at a tertiary hospital in Port Harcourt, Nigeria","authors":"Simeon C. Amadi, P. Awoyesuku, H. Omunakwe, Linda Dublin-Green, U. Ocheche, Chinweowa Ohaka","doi":"10.4103/njm.njm_130_22","DOIUrl":"https://doi.org/10.4103/njm.njm_130_22","url":null,"abstract":"Background: Blood transfusion is an important part of patient management in obstetrics and gynaecology. There is a need to periodically assess blood transfusion practices in order to identify areas for improvement. Objectives: This study aimed to determine the rate of blood transfusion, indications, local use pattern, and variability of blood type transfused. Patients, Materials and Methods: A prospective observational study over six months was conducted at the Rivers State University Teaching Hospital. Obstetric patients in the peripartum period and gynaecological admissions who underwent blood transfusion were included. The patients' characteristics, blood type, pretransfusion packed cell volume (PCV), indication for transfusion, blood product used, number of pints, and donor group were recorded. Analysis was performed using SPSS version 23, and statistical significance was set at P < 0.05. Results: Overall, 84 out of 1000 patients were transfused, giving a rate of 8.4%, 7.4% in obstetric patients, and 13% in gynaecological patients. Haemorrhage was the main reason for transfusions in obstetrics 40 (65.6%), made up of postpartum haemorrhage 27 (44.3%) and antepartum haemorrhage 13 (21.3%), while antepartum anaemia was 17 (27.9%). In gynaecology, chronic anaemia was the main reason for transfusions 10 (43.5%), while acute haemorrhage was 7 (30.4%). Blood components used were whole blood 66.7% (56/84) and sedimented blood 33.3% (28/84) only. About a quarter of the patients who received blood transfusion, had a pretransfusion PCV of 25% or more (20/84) and received only one pint of blood (21/84). Conclusion: The rate of blood transfusion was relatively high, with gynaecology rates higher than obstetric. The indication for blood transfusion in obstetrics was mainly haemorrhage, while in gynaecology, it was chronic anaemia.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"32 1","pages":"28 - 34"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47887008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Complex Adult Congenital Heart Disease: A Rare Case of Dextrocardia with Double-outlet Right Ventricle 复杂成人先天性心脏病:右心双出口右心室一例
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_61_23
Adeola Olubunmi Ajibare, Oluwaseye Michael Oladimeji, Oluwafemi Tunde Ojo, Folasade Adeola Daniel, Philip Alaba Adebola, Abdulazeez Olanrewaju
{"title":"Complex Adult Congenital Heart Disease: A Rare Case of Dextrocardia with Double-outlet Right Ventricle","authors":"Adeola Olubunmi Ajibare, Oluwaseye Michael Oladimeji, Oluwafemi Tunde Ojo, Folasade Adeola Daniel, Philip Alaba Adebola, Abdulazeez Olanrewaju","doi":"10.4103/njm.njm_61_23","DOIUrl":"https://doi.org/10.4103/njm.njm_61_23","url":null,"abstract":"Abstract Double-outlet right ventricle (DORV) is a complex and rare congenital heart disease (CHD), which is usually symptomatic early in childhood and thus diagnosed early. Dextrocardia is another rare CHD that can occur either as an isolated cardiac abnormality or may be associated with other complex cardiac defects. However, the co-occurrence of DORV and dextrocardia is rare, especially in adult life. We present a 35-year-old Nigerian lady with situs inversus totalis and complex CHD, which included dextrocardia with multiple congenital intracardiac shunts, DORV occurring with L-malpositioning of the great vessels, atrial septal defect, and ventricular septal defect with partial anomalous pulmonary venous drainage, persistent left superior vena cava as well as severe pulmonary stenosis.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135650535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospital Prevalence, Delay in Diagnosis, and Sociodemographic Features of Hidradenitis Suppurativa in Nigeria: A Multicentre Retrospective Study 尼日利亚化脓性汗腺炎的医院患病率、诊断延误和社会人口学特征:一项多中心回顾性研究
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_67_23
Ehiaghe Lonia Anaba, Obumneme Emeka Okoro, Perpetua Ibekwe, Hadiza Sani, Bolaji Ibiesa Otike-Odibi, Eshan Blessing Henshaw
{"title":"Hospital Prevalence, Delay in Diagnosis, and Sociodemographic Features of Hidradenitis Suppurativa in Nigeria: A Multicentre Retrospective Study","authors":"Ehiaghe Lonia Anaba, Obumneme Emeka Okoro, Perpetua Ibekwe, Hadiza Sani, Bolaji Ibiesa Otike-Odibi, Eshan Blessing Henshaw","doi":"10.4103/njm.njm_67_23","DOIUrl":"https://doi.org/10.4103/njm.njm_67_23","url":null,"abstract":"Abstract Background: Hidradenitis suppurativa (HS) is rare in Africans and so not commonly documented in this population. Aim: We aimed to document the hospital prevalence, sociodemographic factors, delay in diagnosis, and factors associated with a delay in diagnosis. Materials and Methods: This multicentre retrospective study of 64 HS patients was conducted across seven outpatient dermatology clinics in Nigeria. Data spanning 2017 and 2022 were retrieved following ethical approval. Extracted information included age at onset, age at diagnosis, delay in diagnosis, gender, family history of HS, body mass index, smoking history, socioeconomic status, and Hurley stage. Data were analysed using IBM Statistics version 26. For all statistical tests, P < 0.05 was considered statistically significant. Results: Thirteen thousand six-hundred and two new patients composed of 5850 males and 7752 females attended the clinics and 64 of them had HS giving a hospital prevalence of 0.47% (64/13,602). Most of the HS (70.3%) were female. The median (interquartile range) age of the patients was 30 (24, 36) years and the age range was 12–59 years. Age at diagnosis was 20–39 years in 76.6%. There was a delay in diagnosis in 45.3%, a significant relationship between delay in diagnosis with duration and severity of HS with P < 0.001 and P < 0.005, respectively. Conclusion: HS is uncommon in Nigeria. Diagnosis is frequently delayed and patients present with a severe form of the disease. Furthermore, HS is rare among individuals with a low socioeconomic status. There is a need for more awareness and prompt referral of this debilitating disease at the primary health-care level.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135650897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of p21 Expression in Cervical Carcinoma at a Tertiary Institution in Ghana: An Immunohistochemical Study p21在加纳高等教育机构宫颈癌中的表达分析:免疫组织化学研究
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_69_23
Babatunde Moses Duduyemi, Ebenezer Kojo Addai, Kweku Bedu-Addo
{"title":"Analysis of p21 Expression in Cervical Carcinoma at a Tertiary Institution in Ghana: An Immunohistochemical Study","authors":"Babatunde Moses Duduyemi, Ebenezer Kojo Addai, Kweku Bedu-Addo","doi":"10.4103/njm.njm_69_23","DOIUrl":"https://doi.org/10.4103/njm.njm_69_23","url":null,"abstract":"Abstract Background: Cervical cancer is one of the leading causes of female mortality worldwide. About 85% occur in low-income countries with 13.8% incidence and 14% death in Ghana. p21 has been overexpressed in many cancers. Its overexpression in cervical cancer is linked to tumor growth and a bad prognosis. Aim: The expression profile of p21 in our setting is largely unknown, therefore, the necessity to evaluate p21 expression in cervical cancer. Materials and Methods: A retrospective and descriptive study design was employed to investigate p21 expression in association with demographic and clinicopathological features on formalin-fixed paraffin-embedded cervical cancer tissues. The age, histologic type, and tumor grade of patients were abstracted from the hospital records between January 1, 2015, and December 31, 2016. Tissue microarray of suitable blocks was constructed, and immunohistochemistry was performed. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) version 26. Results: One hundred and thirty-five cases were used for the study with an age range of 31–115 years and mean age of 58.93 years (standard deviation ± 17.88). Majority of the cases were postmenopausal (40–59 years). Squamous cell carcinoma (SCC) was the most common histological type (96.3%) with the nonkeratinizing variant having the highest frequency (53.1%). Majority of the cases were high grade; Grade 2 (33.3%) and Grade 3 (49.6%). Majority of the cases (66.7%) stained positive for p21 antibody. The associations between p21 and the clinicopathological characteristics were not statistically significant ( P &gt; 0.05). p21 was more overexpressed in SCC (64.8%) than adenocarcinoma. Conclusion: An overexpression of p21 in this study suggests that it may contribute to antiapoptosis in cervical cancer leading to tumor progression, aggressive behavior, and poor prognosis.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135650242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, associated factors, and outcomes of singleton preterm births at a Tertiary Hospital in Port-Harcourt, Nigeria 尼日利亚哈科特港一家三级医院单胎早产的患病率、相关因素和结局
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_1_23
P. Awoyesuku, D. John, A. Josiah, L. Sapira-Ordu, Chinweowa Ohaka, Simeon C. Amadi
{"title":"Prevalence, associated factors, and outcomes of singleton preterm births at a Tertiary Hospital in Port-Harcourt, Nigeria","authors":"P. Awoyesuku, D. John, A. Josiah, L. Sapira-Ordu, Chinweowa Ohaka, Simeon C. Amadi","doi":"10.4103/njm.njm_1_23","DOIUrl":"https://doi.org/10.4103/njm.njm_1_23","url":null,"abstract":"Background: Preterm birth poses an important management challenge and is a major public health problem associated with a higher perinatal morbidity and mortality. Although the rates of preterm birth are reportedly high in sub-Saharan Africa, there are little available data on factors associated with preterm birth in this sub-region. Aim: To determine the prevalence, associated factors, and outcomes of preterm births in a tertiary care centre in Nigeria. Materials and Methods: A retrospective case–control study of preterm births, in a two-year period between January 2020 and December 2021, was conducted at the Rivers State university teaching hospital. An unmatched control group of term births was used for comparison. Data were retrieved from the hospital records of all the participants using a structured pro forma. Data were analysed using IBM SPSS version 23 and the significance was set at P < 0.05. Results: Of 3476 singleton birth, 258 (7.4%) were preterm births. Six patients had incomplete data and were excluded from further analysis. Majority, 167 (66.3%), were moderate preterm, gestational age (GA) 32–35. The mean GA at birth was 32.02 ± 2.26 weeks. Majority were aged 31–40 years and parity of 2–4. Stillbirths were 71/252 (28.2%) and 19/101 (18.8%) admitted to the neonatal intensive care unit (NICU) suffered early neonatal death. Preterm birth was more likely in unbooked women, those who developed pregnancy-induced hypertension/eclampsia and following prelabour rupture of membranes (PROM). Babies <32 weeks were more likely delivered by spontaneous vaginal delivery and suffered birth asphyxia. Conclusion: The preterm birth prevalence among singleton gestation was 7.4% and remains a significant factor for perinatal death. Hypertensive disorders of pregnancy, PROM, and lack of antenatal care were identified as risk factors.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"32 1","pages":"80 - 87"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41895897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usability of Surveillance Outbreak Response Management and Analysis System for Coronavirus Disease among Epidemiology Officers in Delta State Nigeria 尼日利亚三角洲州流行病学官员冠状病毒病监测、疫情应对管理和分析系统的可用性
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_51_23
Olise Ozakpo, Nyemike S. Awunor, Patrick G. Oyibo, Mamodesan T. Okumagba
{"title":"Usability of Surveillance Outbreak Response Management and Analysis System for Coronavirus Disease among Epidemiology Officers in Delta State Nigeria","authors":"Olise Ozakpo, Nyemike S. Awunor, Patrick G. Oyibo, Mamodesan T. Okumagba","doi":"10.4103/njm.njm_51_23","DOIUrl":"https://doi.org/10.4103/njm.njm_51_23","url":null,"abstract":"Abstract Introduction: Nigeria recently used electronic surveillance tools for epidemic diseases, one such tool is the Surveillance Outbreak Response Management and Analysis System (SORMAS); no readily available study has assessed the use of SORMAS in Nigeria. The title of this study is the usability of SORMAS for coronavirus disease among epidemiological officers in Delta State; it explored the ease of use, the effectiveness of SORMAS, its applicability, and the challenges with its use. Materials and Methods: This descriptive qualitative study involved disease surveillance and notification officers (DSNOs) and their assistants DSNOs in the year 2022; 25 of them were interviewed using two audio tape recorders after consent was obtained. Ethical clearance was obtained from the appropriate body. Thematic content analysis, with the help of Analysis of Qualitative Data software, was used to analyze data. Results: The findings showed that SORMAS was difficult to use for 100% of the respondents, particularly at the initial time, and subsequent use was relatively easy. About 100% of users found SORMAS to be effective for coronavirus disease 2019 surveillance and claimed it could be applied to other health diseases. About 100% of the respondents had challenges which included network problems, unavailability of adequate airtime, low technological know-how, software glitch, and hardware issues, among others. Conclusion: This study helped to outline the factors affecting SORMAS use, demonstrated that SORMAS was relatively easy to use after repeated training, was deemed effective by all respondents; applied to other health diseases, and its use was affected by several challenges.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"275 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135650239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Antinuclear Antibodies, Anti-Beta 2-Glycoprotein-1, and Thyroid Peroxidase Autoantibody Levels in Human Immunodeficiency Virus Sero-positive Pregnant Women at Nnamdi Azikiwe University Teaching Hospital, Nnewi Nigeria 尼日利亚Nnamdi Azikiwe大学教学医院人类免疫缺陷病毒血清阳性孕妇的抗核抗体、抗β 2-糖蛋白-1和甲状腺过氧化物酶自身抗体水平评估
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_59_23
John Ekenedirichukwu Okwara, Joseph Eberendu Ahaneku, Charles Chinedum Onyenekwe, Gerald Okanandu Udigwe, Joseph Ifeanyichukwu Ikechebelu, Emmanuel Chidiebere Okwara, Nuratu Adejumoke Okwara, Salaam Mujeeb, Emeka Callistus Onyeka Izuchukwu
{"title":"Assessment of Antinuclear Antibodies, Anti-Beta 2-Glycoprotein-1, and Thyroid Peroxidase Autoantibody Levels in Human Immunodeficiency Virus Sero-positive Pregnant Women at Nnamdi Azikiwe University Teaching Hospital, Nnewi Nigeria","authors":"John Ekenedirichukwu Okwara, Joseph Eberendu Ahaneku, Charles Chinedum Onyenekwe, Gerald Okanandu Udigwe, Joseph Ifeanyichukwu Ikechebelu, Emmanuel Chidiebere Okwara, Nuratu Adejumoke Okwara, Salaam Mujeeb, Emeka Callistus Onyeka Izuchukwu","doi":"10.4103/njm.njm_59_23","DOIUrl":"https://doi.org/10.4103/njm.njm_59_23","url":null,"abstract":"Abstract Background: Pregnancy is associated with biochemical alterations and may be compounded by human immunodeficiency virus (HIV) infection potentially affecting pregnancy outcome. Aims: This study evaluated some biochemical parameters that could possibly affect pregnancy outcomes in HIV-infected women. Patients, Materials and Methods: The study involved 136 HIV sero-positive on highly active antiretroviral therapy (HAART) and 137 HIV sero-negative pregnant women, recruited from the Antenatal Clinic of Nnamdi Azikiwe University Teaching Hospital, Nnewi. Antinuclear antibodies (ANAs), anti-beta 2-glycoprotein-1 (βGP1), and thyroid peroxidase autoantibody (TPOab) were analysed using the enzyme-linked immunosorbent assay methods. Results: TPOab in HIV sero-positive subjects (104.9 ± 51.06 IU/mL) was significantly higher ( P &gt; 0.05) compared with controls (89.5 ± 33.5 IU/mL). ANA and βGP1 in test group (0.89 ± 0.31; 12.94 ± 8.9, respectively) did not change significantly ( P &gt; 0.05) compared with the controls (0.84 ± 0.27; 10.37 ± 9.6, respectively). There were no significant changes in measured biochemical parameters between trimesters ( P &gt; 0.05). Furthermore, there were no significant differences in measured biochemical parameters between subjects with different APGAR scores in all subject groups. Conclusion: HIV infection affected TPOab level but had no impact on ANA, bGP1, and APGAR score in HIV pregnancy under HAART.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"168 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135650534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personality Traits as Key Determinants of COVID-19 Vaccine Uptake among Healthcare Workers in Nigeria 人格特征是尼日利亚医护人员接种COVID-19疫苗的关键决定因素
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_40_23
Mohammed Yusuf Mahmood, Abdurrahman Ashiru, Falmata Baba Shettima, Abdulkareem Abashe Abdullahi, Abdulhakeem Mamman Ngulde, Zaharadeen Umar Abbas, Inuwa Murtala Jibrin, Umar Baba Musami, Ibrahim Abdu Wakawa
{"title":"Personality Traits as Key Determinants of COVID-19 Vaccine Uptake among Healthcare Workers in Nigeria","authors":"Mohammed Yusuf Mahmood, Abdurrahman Ashiru, Falmata Baba Shettima, Abdulkareem Abashe Abdullahi, Abdulhakeem Mamman Ngulde, Zaharadeen Umar Abbas, Inuwa Murtala Jibrin, Umar Baba Musami, Ibrahim Abdu Wakawa","doi":"10.4103/njm.njm_40_23","DOIUrl":"https://doi.org/10.4103/njm.njm_40_23","url":null,"abstract":"Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic has posed a significant global challenge, necessitating the development and administration of vaccines to halt its spread. Nevertheless, there is limited information on the predictors, patterns, and personality variables influencing COVID-19 vaccine uptake among Nigerian health-care workers (HCWs). Aim: The study set to assess level of factors including personality factors that influence acceptance of the COVID-19 vaccines among.HCWs in Nigeria. Materials and Methods: From August 9 to October 11, 2021, a web-based, cross-sectional survey was conducted on 300 HCWs in Nigeria, aged 19 and above, with social media access and English language proficiency. Descriptive statistics, Chi-square, and binary logistic regression were used to analyse the data on the SPSS version 20. Results: The findings revealed that while 64% of those who participated in the study received the first dosage of the COVID-19 vaccine, only 48.3% returned for the second dose. The impression of heightened susceptibility to contracting COVID-19 was the primary reason for vaccination uptake. Although education level was associated with vaccination uptake, it did not predict it independently. The age distribution, agreeableness, conscientiousness, and high vulnerability as a rationale for receiving a vaccine were all the independent predictors of vaccine uptake. Conclusion: This study reveals that despite their role as vaccination advocates, HCWs can exhibit hesitancy toward novel vaccines. To increase vaccine uptake among HCWs and the general population, it is crucial to recognise the factors that influence vaccine acceptance among them, including individual personality variables, and incorporate this understanding into vaccination promotion programs.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135651097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral Neurofibroma: 10-Year Experience in Enugu 口腔神经纤维瘤:埃努古10年经验
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_133_22
M. Nwoga
{"title":"Oral Neurofibroma: 10-Year Experience in Enugu","authors":"M. Nwoga","doi":"10.4103/njm.njm_133_22","DOIUrl":"https://doi.org/10.4103/njm.njm_133_22","url":null,"abstract":"Background: Neurofibroma (NF) is a neural tumour derived from the proliferation of Schwann cells. Oral NF is rare, and no known study exists in the Nigerian literature. Aims: The aim was to study the clinicopathologic features of oral NF in a tertiary hospital in Enugu and review of the literature. Materials and Methods: This was a retrospective study conducted in a tertiary health institution in Enugu from April 2012 to March 2022. The clinical records, radiographs, and histopathology reports of patients seen at the department of oral pathology and oral medicine were examined for cases of NF. The data were analyzed using descriptive statistics, and Chi-square statistics for association between the variables. Results: There were only 11 oral peripheral neural sheath tumours, and all were diagnosed as NF. These constitute 1.1% of 897 orofacial biopsies received. Solitary oral NF constituted 90.9% of cases, while 9.1% was associated with neurofibromatosis type I. One of the solitary cases occurred with ameloblastoma. The mean age at the onset of the tumour was 38 ± 24.4 years (range: 8–85 years). A male-to-female ratio of 1.8:1 was obtained, and a majority of lesions, 7 (63.6%) of 11, were located in soft tissue sites only. The tongue (27.3%) and the mandible (27.3%) were the most common intraosseous and soft tissue sites. Pain (18.2%) and recurrence (54.5%) were observed. Conclusion: Oral NF was the most common peripheral nerve sheath tumour, with a low prevalence, male predilection, and frequently extraosseous.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"32 1","pages":"35 - 38"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43132483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Metastatic Paratesticular Tumour in a Resource-Poor Setting 资源贫乏地区转移性睾丸旁肿瘤的治疗
Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI: 10.4103/njm.njm_64_23
Benjamin O. Ayogu, Okwudili C. Amu, Okezie M. Mbadiwe, Solomon Kenechukwu Anyimba, Francis I. Ukekwe, Chukwunonso D. Nwachukwu, Henry N. Akporeha
{"title":"Management of Metastatic Paratesticular Tumour in a Resource-Poor Setting","authors":"Benjamin O. Ayogu, Okwudili C. Amu, Okezie M. Mbadiwe, Solomon Kenechukwu Anyimba, Francis I. Ukekwe, Chukwunonso D. Nwachukwu, Henry N. Akporeha","doi":"10.4103/njm.njm_64_23","DOIUrl":"https://doi.org/10.4103/njm.njm_64_23","url":null,"abstract":"Abstract Paratesticular tumours are tumours that arise from the testicular tunics, spermatic cord, epididymis, or vestigial remnants. The tumours are rare and account for approximately 5% of intrascrotal neoplasms. About 75% of these tumours arise from the spermatic cord. Paratesticular tumours most commonly manifest as painless scrotal masses. Alternatively, the tumour may be incidentally noticed when a scrotal ultrasound scan is done for another intrascrotal pathology such as hydrocele, inguinoscrotal hernia, epididymo-orchitis, or suspected testicular tumour. We present a case of metastatic paratesticular tumour in a 21-year-old Nigerian male, who presented at the University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, in September 2018 at the age of 19 years with a painless right hemiscrotal mass. The patient was clinically evaluated with scrotal ultrasonography, testicular tumour markers, and liver function test. Biopsy specimen obtained was ignorantly discarded by the patient who was subsequently lost to follow-up. Histologic diagnosis of mesenchymal tumour (myxoid liposarcoma) was made two years after his initial presentation when he developed both inguinal and retroperitoneal lymph node metastasis at the age of 21 years. He was evaluated as clinical stage IV disease and then commenced on chemotherapy after baseline investigations. Our objective of presenting this report is to highlight the effect of delayed diagnosis in the management outcome, challenges in the provision of resources in low- and middle-income countries, and to emphasise the rarity of the tumour in our subregion.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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