Gastroenterology and Hepatology最新文献_第9页

Continuing the Dialogue in IBS-C Management: Importance of Individualizing Care and Tailoring Treatment. 继续进行肠易激综合征（IBS-C）管理对话：个体化护理和定制治疗的重要性。

Gastroenterology and Hepatology Pub Date : 2024-10-01

Brennan Spiegel

引用次数: 0

Inflammatory Bowel Disease and Cardiovascular Disease.

Gastroenterology and Hepatology Pub Date : 2024-10-01

Remo Panaccione

引用次数: 0

Remote Monitoring for Patients With Inflammatory Bowel Disease: Current Status and the Future of the Field.

Gastroenterology and Hepatology Pub Date : 2024-10-01

Michelle D Dong, Jessica K Salwen-Deremer, Corey A Siegel

{"title":"Remote Monitoring for Patients With Inflammatory Bowel Disease: Current Status and the Future of the Field.","authors":"Michelle D Dong, Jessica K Salwen-Deremer, Corey A Siegel","doi":"","DOIUrl":"","url":null,"abstract":"As a direct result of the COVID-19 pandemic, many advances in telehealth have been made that save time and reduce travel costs for patients. Telehealth, specifically video visits, was especially embraced by patients with inflammatory bowel disease (IBD). However, remote clinic visits are only one part of the equation for remote IBD care. Patients with Crohn's disease or ulcerative colitis have a significant testing burden, and many strides still need to be made to improve all aspects of their care, including remote monitoring (testing at home) of biochemical markers (eg, C-reactive protein and fecal calprotectin) and drug concentrations. Remote monitoring has the potential to decrease the burden of chronic disease on patients through improved ease of access, both when patients are feeling well and when they are having an exacerbation of symptoms. Numerous technologies are available in other countries, are used in other disease states, or are in the animal or early human testing phases. These innovations in home testing have the potential to improve testing adherence, disease control, and monitoring of IBD for all patients, and will have a particularly significant effect on those living in rural communities. This article reviews the current modalities for remote monitoring of patients with IBD as well as the methods in development to make monitoring of IBD easier for patients.","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 10","pages":"621-627"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and Management of Noncardiac Chest Pain. 非心源性胸痛的诊断和处理。

Gastroenterology and Hepatology Pub Date : 2024-10-01

Tian Li, Manar Al Jawish, Dilhana Badurdeen, Andree H Koop

引用次数: 0

Diagnosing and Treating Noncardiac Chest Pain. 诊断和治疗非心源性胸痛。

Gastroenterology and Hepatology Pub Date : 2024-10-01

Gary R Lichtenstein

引用次数: 0

Rationale for an Eosinophilic Esophagitis Treat-to-Target Concept.

Gastroenterology and Hepatology Pub Date : 2024-10-01

Thomas Greuter, Alex Straumann

{"title":"Rationale for an Eosinophilic Esophagitis Treat-to-Target Concept.","authors":"Thomas Greuter, Alex Straumann","doi":"","DOIUrl":"","url":null,"abstract":"Eosinophilic esophagitis (EoE) is a chronic T helper 2-mediated inflammatory disorder of the esophagus defined clinically by the presence of symptoms of esophageal dysfunction and histologically by an eosinophil-predominant infiltration. Correspondingly, treatment has aimed at controlling both symptom severity and histologic activity. However, with emerging clinical and pathophysiologic understanding of the disease, it has become increasingly apparent that other disease aspects need to be targeted as well, such as endoscopic severity and quality of life. Moreover, with the role of eosinophils having been questioned lately, histologic changes beyond eosinophil infiltration have come to attention and are captured by newly validated scores. In addition, EoE is being increasingly considered a transmural disease that cannot be assessed by simple endoscopy but needs measurement of esophageal distensibility, a surrogate marker for fibrosis. Finally, novel tools such as measurement of esophageal impedance could make it possible to assess for complete restoration of the esophageal epithelium, potentially corresponding to disease clearance. This article reviews the various outcome parameters in adult EoE management and proposes an algorithm for a treat-to-target concept, in analogy to what has been practiced in inflammatory bowel disease treatment for the last 10 years.","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 10","pages":"583-590"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clarifying the Hazy Concepts of Food Allergies and Sensitivities. 澄清食物过敏和敏感的模糊概念。

Gastroenterology and Hepatology Pub Date : 2024-10-01

Lauren Loeb, David C Cangemi, Jacqueline D Squire, Brian E Lacy

引用次数: 0

Helicobacter pylori Antimicrobial Resistance and the Role of Next-Generation Sequencing. 幽门螺杆菌的抗菌耐药性和新一代测序技术的作用。

Gastroenterology and Hepatology Pub Date : 2024-08-01

Christine B Andrews, Michael I Herzlinger, Steven F Moss

{"title":"Helicobacter pylori Antimicrobial Resistance and the Role of Next-Generation Sequencing.","authors":"Christine B Andrews, Michael I Herzlinger, Steven F Moss","doi":"","DOIUrl":"","url":null,"abstract":"Helicobacter pylori infection affects over half of the world's population and is a global health concern because it contributes to chronic and fatal gastrointestinal disorders, including peptic ulcer disease and gastric cancer. The escalating prevalence of antibiotic-resistant strains of H pylori necessitates a change in management. The conventional strategy of empiric-based treatments is becoming increasingly ineffective in both adult and pediatric populations; rates of eradication to common first-line regimens remain suboptimal and continue to decline. Culture-based susceptibility testing for H pylori has been underutilized and challenging to incorporate into practice. Next-generation sequencing (NGS), which can identify the genetic biomarkers that predict antimicrobial resistance and susceptibility patterns, offers a promising alternative. NGS may enable clinicians to tailor individual treatment regimens and contribute to epidemiologic surveillance across populations. As NGS technology advances and becomes more accessible, its integration into routine clinical practice holds the potential to transform H pylori management strategies and improve patient outcomes. This article reviews the literature describing antimicrobial resistance patterns in adult and pediatric practice in the United States and provides practical guidance on the current role of NGS in the management of H pylori.","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 8","pages":"469-476"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastroenterology and Hepatology Pub Date : 2024-08-01

Eamonn M M Quigley, Oscar Noble, Usman Ansari

{"title":"The Suggested Relationships Between Common GI Symptoms and Joint Hypermobility, POTS, and MCAS.","authors":"Eamonn M M Quigley, Oscar Noble, Usman Ansari","doi":"","DOIUrl":"","url":null,"abstract":"An increasing number of reports suggest an association between a newly recognized disease cluster and significant and often disabling gastrointestinal (GI) symptoms. This cluster is composed of diagnoses of hypermobility spectrum disorders (HSDs) such as joint hypermobility and hypermobile variant Ehlers-Danlos syndrome (hEDS), postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS). The diagnosis of these entities remains a challenge, as the pathophysiology of each has not been completely elucidated and the diagnostic criteria continue to evolve. This article describes a cohort of young adult females who shared similar GI symptoms, with intractable nausea and vomiting being most prominent and gastroesophageal reflux disease and constipation also occurring. Most strikingly, these females also exhibited or reported a history of HSD, hEDS, POTS, and/or MCAS. The clinical course of their GI symptoms was remarkable for considerable challenges in management, and artificial nutritional support proved necessary for some. This article describes the clinical features and outcomes of their GI manifestations, examines how these manifestations might be linked to their systemic syndromes, and discusses whether a shared pathophysiology exists. Pending the definition of a common thread between these conditions, this article seeks to raise awareness of their clinical definitions and foster research that will hopefully improve outcomes for these patients.","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 8","pages":"479-489"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conventional vs Full-Thickness Resection Techniques for Large Polyps. 大息肉的传统切除技术与全厚切除技术的比较

Gastroenterology and Hepatology Pub Date : 2024-08-01

Arthur Schmidt

引用次数: 0