The Israel Medical Association journal : IMAJ最新文献_第2页

Does Ethnicity or Sex Have an Impact on Medication Consumption after Arthroscopic Partial Meniscectomy? 种族或性别对关节镜半月板部分切除术后的用药有影响吗？

The Israel Medical Association journal : IMAJ Pub Date : 2026-10-01

Tomer Gazit, Amir Dolev, Barak Haviv, Lee Yaari, Mustafa Yassin, Mohamed Kittani

{"title":"Does Ethnicity or Sex Have an Impact on Medication Consumption after Arthroscopic Partial Meniscectomy?","authors":"Tomer Gazit, Amir Dolev, Barak Haviv, Lee Yaari, Mustafa Yassin, Mohamed Kittani","doi":"","DOIUrl":"","url":null,"abstract":"Background: Pain following arthroscopic partial meniscectomy (APM) varies considerably among patients. Previous studies have suggested that gender and ethnicity may influence postoperative pain after orthopedic procedures. However, limited evidence exists regarding pain differences between Arab and Jewish patients after APM.Objectives: To evaluate the association of gender and ethnicity with postoperative pain and analgesic consumption during the first month after APM.Methods: Patients who underwent primary APM between 2018 and 2019 were retrospectively identified and stratified by gender and ethnicity. Intraoperative findings, including meniscal tear type and cartilage injury, were recorded. Postoperative pain was assessed using the Knee injury and Osteoarthritis Outcome Score (KOOS), analgesic consumption was quantified in grams, and pain sensitivity was evaluated with the Pain Sensitivity Questionnaire (PSQ). Outcomes were analyzed weekly during the first postoperative month.Results: In total, 99 patients were included (65 men, 34 women; 39 Arabs, 60 Jews), comprising 22 Arab men, 43 Jewish men, 17 Arab women, and 17 Jewish women. Women reported lower KOOS scores and consumed more analgesics during weeks 3 and 4. Arab patients also demonstrated lower KOOS scores, higher PSQ scores, and greater analgesic consumption at selected postoperative intervals. Combined analysis showed an additive effect of gender and ethnicity, with Arab women reporting the poorest pain outcomes.Conclusions: Female gender and Arab ethnicity were associated with greater postoperative pain and increased analgesic requirements after APM. These factors should be considered when tailoring postoperative pain management, although baseline differences and cultural influences may partially explain the associations.","PeriodicalId":524150,"journal":{"name":"The Israel Medical Association journal : IMAJ","volume":"28 10","pages":"628-634"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Induction Phase: Should We Keep the Proton Pump Inhibitor in Pediatric Eosinophilic Esophagitis? 诱导期后：我们是否应该保留质子泵抑制剂治疗儿童嗜酸性食管炎？

The Israel Medical Association journal : IMAJ Pub Date : 2026-10-01

Netanel Agajany, Efrat Broide, Tzippora Shalem, Moshe Leshno, Adi Eindor-Abarbanel

{"title":"Beyond the Induction Phase: Should We Keep the Proton Pump Inhibitor in Pediatric Eosinophilic Esophagitis?","authors":"Netanel Agajany, Efrat Broide, Tzippora Shalem, Moshe Leshno, Adi Eindor-Abarbanel","doi":"","DOIUrl":"","url":null,"abstract":"Background: Proton pump inhibitors (PPIs) are a common and effective management strategy for eosinophilic esophagitis (EoE) leading to successful remission in most cases. However, there is uncertainty regarding the ideal follow-up pharmacological treatment to maintain remission. We performed a cost-effectiveness and quality-adjusted life year (QALY) analysis.Objectives: To compare various approaches of pharmacologic treatments for EoE.Methods: A Markov model was constructed to evaluate the cost-effectiveness and QALY of maintenance therapies for eosinophilic esophagitis, including PPI, topical corticosteroids (tCS), and no treatment strategy, with crossover in treatments for primary and secondary nonresponse. The primary outcomes were incremental cost-effectiveness and QALY at a 5-year time horizon.Results: In the base-case scenario (5-year time horizon), the average costs were no treatment:₪ 73,075, PPI:₪ 81,455, and tCS:₪ 145,669 as maintenance therapy, with PPI being the dominant strategy (more effective/less costly), and a QALY of 45543, 4.5538, and 4.2283, respectively.Conclusions: PPI was the most effective/least costly maintenance therapy. PPI is also the most cost-effective pharmacologic strategy. The relatively low adverse effects of this treatment, in addition to its effectiveness and low cost, make it an ideal choice following successful PPI induction treatment.","PeriodicalId":524150,"journal":{"name":"The Israel Medical Association journal : IMAJ","volume":"28 10","pages":"646-651"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric Tear Gas Poisoning in Southern Israel: Clinical Characteristics and Outcomes. 以色列南部儿童催泪瓦斯中毒：临床特征和结果

The Israel Medical Association journal : IMAJ Pub Date : 2026-10-01

Or Kaplan, Eyal Pasternak, Gidon Test, Inbal Kestenbom, Oren Tavor

{"title":"Pediatric Tear Gas Poisoning in Southern Israel: Clinical Characteristics and Outcomes.","authors":"Or Kaplan, Eyal Pasternak, Gidon Test, Inbal Kestenbom, Oren Tavor","doi":"","DOIUrl":"","url":null,"abstract":"Background: Pepper spray and tear gas are chemical irritants causing ocular, dermal, and respiratory injury. Data specific to pediatric emergency department (PED) presentations remain limited.Objectives: To characterize the epidemiology, clinical presentation, and short-term outcomes of chemical irritant exposure in children presenting to a tertiary PED.Methods: We conducted a retrospective cohort study of patients aged 0-18 years of age presenting to a single tertiary PED between 2016 and 2024 following civilian-grade chemical irritant exposure. Cases were identified using ICD-9 codes and free-text electronic medical records search. Demographic characteristics, clinical findings, treatment, and disposition were analyzed using descriptive statistics.Results: We included 84 pediatric patients (median age 12.5 years, IQR 6.0-15.6; 69.0% male). Exposures occurred most commonly at home (44.0%) and school (36.9%). Ocular involvement was common. Superficial punctate keratitis was identified in 54.5% of patients who underwent fluorescein examination by ophthalmologist (21.5% of the total cohort). Respiratory and dermal symptoms were mild and self-resolving. No severe complications were documented; 96.4% were discharged home.Conclusions: Civilian-grade chemical irritant exposures in children were predominantly self-limited and managed successfully with conservative ED care, supporting decontamination-based protocols while highlighting home and school settings as priorities for prevention.","PeriodicalId":524150,"journal":{"name":"The Israel Medical Association journal : IMAJ","volume":"28 10","pages":"635-639"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Jewish Tradition and Patient Communication. 犹太传统和病人沟通。

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Jeffrey H Lipton

引用次数: 0

Healthcare Utilization and Medication Use in Patients with Psoriasis: A Population-Based Study. 银屑病患者的医疗保健利用和药物使用：一项基于人群的研究

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Eran Shavit, Yochai Schonmann, Arnon D Cohen

{"title":"Healthcare Utilization and Medication Use in Patients with Psoriasis: A Population-Based Study.","authors":"Eran Shavit, Yochai Schonmann, Arnon D Cohen","doi":"","DOIUrl":"","url":null,"abstract":"Background: Healthcare utilization in patients with psoriasis has been described from the perspective of psoriasis healthcare centers. Psoriasis healthcare utilization at the population level, including appointments with family physicians, impacts the overall financial expenditure.Objectives: To describe the utilization of healthcare services in patients with psoriasis compared to the general non-psoriasis population.Methods: We conducted a cross-sectional, population-based analysis of data from Clalit Health Services, the largest public health service provider in Israel, comparing the annual healthcare utilization and medication consumption of all Clalit members with psoriasis in 2023 with an age- and sex-matched group at a primary care clinic. We compared up to five non-psoriasis items.Results: The study included 835,422 people (140,927 individuals with psoriasis and 694,671 without). Patients with psoriasis had more annual physician appointments than controls, and the meetings were longer. Patients with psoriasis took more sick leave and required more hospital admission compared to the control group. Tumor necrosis factor (TNF) inhibitors were prescribed much more often to patients with psoriasis than to the control group (3147 patients vs. 1857 in the matched control). More IL-17 blockers and IL-23 blockers were also prescribed more in the psoriasis group, although at a much lower level than the TNF inhibitors.Conclusions: Patients with psoriasis used more healthcare services than the control group. Healthcare providers should allocate more resources to psoriasis care, both for primary care and at specialized psoriasis centers.","PeriodicalId":524150,"journal":{"name":"The Israel Medical Association journal : IMAJ","volume":"28 9","pages":"564-571"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent Transthyretin Cardiac Amyloidosis and Eosinophilic Myocarditis: A Case Report. 转甲状腺素性心脏淀粉样变性合并嗜酸性心肌炎1例报告。

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Jen Hojman, Gil Moravsky, Itzhak Vitkon Barkay, Oran Tzuman, Ronit Koren

引用次数: 0

Hemophagocytic Lymphohistiocytosis Following Systemic Bacillus Calmette-Guérin Infection: A Rare Complication of a Common Procedure. 系统性卡介苗-谷青孢杆菌感染后的噬血细胞淋巴组织细胞增多症：一种常见手术的罕见并发症。

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Daniel Leshin-Carmel, Evgenia Tsyba

引用次数: 0

Age-Period-Cohort Analysis of Creutzfeldt-Jakob Disease in Israel (1985-2019). 以色列克雅氏病年龄-时期-队列分析（1985-2019）

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Yacov Balash, Esther Kahana, Ronit Gilad, Anda Eilam, Amos D Korczyn

{"title":"Age-Period-Cohort Analysis of Creutzfeldt-Jakob Disease in Israel (1985-2019).","authors":"Yacov Balash, Esther Kahana, Ronit Gilad, Anda Eilam, Amos D Korczyn","doi":"","DOIUrl":"","url":null,"abstract":"Background: Although the epidemiology of Creutzfeldt-Jakob disease (CJD) in Israel has been studied extensively, it is unknown whether its incidence is mainly a result of vertical transmission due to the high penetrance of the E200K mutation in patients with familial CJD (f-CJD) compared to sporadic CJD (s-CJD), or whether there are other yet undiscovered contributing factors.Objectives: To conduct an age-period-cohort (APC) analysis of Creutzfeldt-Jakob disease in Israel.Methods: In this APC analysis, we used a web-based statistical tool to identify whether patient age, period of birth, and cohort had any effect on incidence trends of s-CJD and f-CJD.Results: APC analysis demonstrated no significant shifts in net drift, indicating the absence of any overall trend of changes over time. Cohort analysis revealed that individuals affected by either s-CJD or f-CJD who were mostly born in Israel in the second half of the 20th century exhibited the same risk as those born mainly in Libya at the beginning of 20th century. There were no changes in risk of s-CJD and f-CJD between 1985 and 2019.Conclusions: The incidence rates of s-CJD and f-CJD in Israel have remained unchanged, indicating that the probability of a future increase in the incidence is negligible.","PeriodicalId":524150,"journal":{"name":"The Israel Medical Association journal : IMAJ","volume":"28 9","pages":"572-577"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and Predictors of Vitamin B6 Deficiency in Hemodialysis Patients Not Receiving Vitamin Supplementation. 未接受维生素补充的血液透析患者维生素B6缺乏症的患病率和预测因素

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Eilam Rabina, Tal Baharal Bergner, Naomi Nacasch, Avraham Levian, Gloria Rashid, Eran Neumark, Guy Topaz, Ayala Shiri, Mohammad Shamiea, Osnat Jarchowsky Dolberg, Keren Cohen-Hagai

{"title":"Prevalence and Predictors of Vitamin B6 Deficiency in Hemodialysis Patients Not Receiving Vitamin Supplementation.","authors":"Eilam Rabina, Tal Baharal Bergner, Naomi Nacasch, Avraham Levian, Gloria Rashid, Eran Neumark, Guy Topaz, Ayala Shiri, Mohammad Shamiea, Osnat Jarchowsky Dolberg, Keren Cohen-Hagai","doi":"","DOIUrl":"","url":null,"abstract":"Background: Vitamin B6 is an essential cofactor in amino acid metabolism. Its deficiency is linked to neuropathy, anemia, and cardiovascular risk. Deficiency is common among hemodialysis patients due to dialytic losses and restrictive diets; however, data related to high-flux (HF) dialysis membranes and Mediterranean dietary patterns are scarce.Objectives: To assess the prevalence and determinants of deficiency in unsupplemented Israeli hemodialysis patients.Methods: This retrospective chart review, utilizing a cross-sectional design, was conducted in August 2024. We included 27 chronic hemodialysis patients not receiving vitamin B6 supplementation, representing the available unsupplemented cohort from a unit of approximately 150 patients. Vitamin B6 status was assessed by measuring plasma pyridoxal-5'-phosphate (PLP); deficiency < 20 ng/ml. Clinical and nutritional parameters were evaluated to identify deficiency.Results: Vitamin B6 deficiency was noted in 63% of patients (median PLP 18 ng/ml, interquartile range 13-23). The cohort was 67% male, median age 74 years. All patients were treated with HF dialyzers. No significant correlations were found between PLP levels and nutritional indices or laboratory markers. A non-significant trend was observed between older age and lower PLP levels (r = -0.35, P = 0.098).Conclusions: Vitamin B6 deficiency was common among Israeli hemodialysis patients treated with HF dialyzers, despite a presumed Mediterranean diet. It was not associated with nutritional status, suggesting dialysis-related losses, potentially augmented by high-flux membranes, may outweigh intake. Given the high prevalence of deficiency and low cost, routine low-dose vitamin B6 supplementation may be warranted, particularly in older patients.","PeriodicalId":524150,"journal":{"name":"The Israel Medical Association journal : IMAJ","volume":"28 9","pages":"578-583"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Prevention of IgE-mediated Cow's Milk Allergy Is Feasible: A Position Statement by the Israeli Association of Allergy and Clinical Immunology. ige介导的牛奶过敏的一级预防是可行的：以色列过敏和临床免疫学协会的立场声明。

The Israel Medical Association journal : IMAJ Pub Date : 2026-09-01

Idit Lachover-Roth, Ilan Dalal, Avraham Beigelman, Alon Hershko, Yuval Tal, Ramit Maoz Segal, Aharon Kessel, Arnon Elizur

引用次数: 0