Does Ethnicity or Sex Have an Impact on Medication Consumption after Arthroscopic Partial Meniscectomy?

Tomer Gazit, Amir Dolev, Barak Haviv, Lee Yaari, Mustafa Yassin, Mohamed Kittani
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Abstract

Background: Pain following arthroscopic partial meniscectomy (APM) varies considerably among patients. Previous studies have suggested that gender and ethnicity may influence postoperative pain after orthopedic procedures. However, limited evidence exists regarding pain differences between Arab and Jewish patients after APM.

Objectives: To evaluate the association of gender and ethnicity with postoperative pain and analgesic consumption during the first month after APM.

Methods: Patients who underwent primary APM between 2018 and 2019 were retrospectively identified and stratified by gender and ethnicity. Intraoperative findings, including meniscal tear type and cartilage injury, were recorded. Postoperative pain was assessed using the Knee injury and Osteoarthritis Outcome Score (KOOS), analgesic consumption was quantified in grams, and pain sensitivity was evaluated with the Pain Sensitivity Questionnaire (PSQ). Outcomes were analyzed weekly during the first postoperative month.

Results: In total, 99 patients were included (65 men, 34 women; 39 Arabs, 60 Jews), comprising 22 Arab men, 43 Jewish men, 17 Arab women, and 17 Jewish women. Women reported lower KOOS scores and consumed more analgesics during weeks 3 and 4. Arab patients also demonstrated lower KOOS scores, higher PSQ scores, and greater analgesic consumption at selected postoperative intervals. Combined analysis showed an additive effect of gender and ethnicity, with Arab women reporting the poorest pain outcomes.

Conclusions: Female gender and Arab ethnicity were associated with greater postoperative pain and increased analgesic requirements after APM. These factors should be considered when tailoring postoperative pain management, although baseline differences and cultural influences may partially explain the associations.

种族或性别对关节镜半月板部分切除术后的用药有影响吗?
背景:关节镜半月板部分切除术(APM)后的疼痛在不同患者之间有很大差异。先前的研究表明,性别和种族可能影响骨科手术后的术后疼痛。然而,关于阿拉伯人和犹太人患者APM后疼痛差异的证据有限。目的:评估性别和种族与APM术后第一个月疼痛和镇痛药物消耗的关系。方法:回顾性分析2018年至2019年间接受原发性APM的患者,并按性别和种族进行分层。记录术中发现,包括半月板撕裂类型和软骨损伤。术后疼痛采用膝关节损伤和骨关节炎结局评分(kos)评估,镇痛药用量以克为单位量化,疼痛敏感性采用疼痛敏感性问卷(PSQ)评估。术后第一个月每周对结果进行分析。结果:共纳入99例患者(男性65例,女性34例;阿拉伯人39例,犹太人60例),其中阿拉伯男性22例,犹太男性43例,阿拉伯女性17例,犹太女性17例。在第3周和第4周,女性报告的KOOS评分较低,服用的镇痛药较多。阿拉伯患者也表现出较低的kos评分,较高的PSQ评分,以及在术后选择的时间间隔内更多的止痛药消耗。综合分析显示了性别和种族的叠加效应,阿拉伯妇女报告的疼痛结果最差。结论:女性性别和阿拉伯民族与APM术后疼痛和镇痛需求增加有关。尽管基线差异和文化影响可能部分解释了这些关联,但在调整术后疼痛管理时应考虑这些因素。
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