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Application of Frequency Features of Optical Flow for Event Detection in Video-EEG Monitoring Data 光流频率特征在视频-脑电监测数据事件检测中的应用
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-30 DOI: 10.18287/jbpe21.07.030301
D. Murashov, Y. Obukhov, I. Kershner, M. Sinkin
{"title":"Application of Frequency Features of Optical Flow for Event Detection in Video-EEG Monitoring Data","authors":"D. Murashov, Y. Obukhov, I. Kershner, M. Sinkin","doi":"10.18287/jbpe21.07.030301","DOIUrl":"https://doi.org/10.18287/jbpe21.07.030301","url":null,"abstract":". The work is devoted to the study of the frequency features of the optical flow obtained from the video record of long-term video-electroencephalographic (video-EEG) monitoring data of patients with epilepsy. It is necessary to obtain features to recognize epileptic seizures and differentiate them from non-epileptic events. We propose to analyze the periodograms of the smoothed optical flow computed from the fragments of the patient ’ s video recordings. We use Welch's method to obtain periodograms. The values of the power spectral density of the optical flow at the selected frequencies are used as features. Using the clustering algorithm, seven groups of events are identified in video recordings and combined into three generalized classes. We train SVM classifier and conduct recognition of events in a test sample of 103 video fragments in four patients. The experiment indicates the accuracy of event classification equal to 90.3%. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46471184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperspectral Camera – Attachment for Microscopy 高光谱照相机。显微镜用附件
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-30 DOI: 10.18287/jbpe21.07.030405
Mohammed M. Hamza, Ali Hamandi, A. Makarov, V. Podlipnov, R. Skidanov
{"title":"Hyperspectral Camera – Attachment for Microscopy","authors":"Mohammed M. Hamza, Ali Hamandi, A. Makarov, V. Podlipnov, R. Skidanov","doi":"10.18287/jbpe21.07.030405","DOIUrl":"https://doi.org/10.18287/jbpe21.07.030405","url":null,"abstract":". The paper presents a microscope equipped with a hyperspectral ocular nozzle with a phase diffraction grating, which is used as a dispersing element. The spectral range of the device is 400 – 1000 nm, with the spectral resolution of 5 nm. The paper describes a microscope software that is used to solve problems of spectral analysis. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47193324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Characterization of Polarization Holographic Gratings Obtained on Azopolymer Thin Films by Digital Holographic Microscopy 偶氮聚合物薄膜上偏振全息光栅的数字全息显微镜表征
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-30 DOI: 10.18287/jbpe21.07.030306
V. Cazac, C. Loshmanschii, E. Achimova, A. Meshalkin, V. Abashkin, V. Podlipnov
{"title":"Characterization of Polarization Holographic Gratings Obtained on Azopolymer Thin Films by Digital Holographic Microscopy","authors":"V. Cazac, C. Loshmanschii, E. Achimova, A. Meshalkin, V. Abashkin, V. Podlipnov","doi":"10.18287/jbpe21.07.030306","DOIUrl":"https://doi.org/10.18287/jbpe21.07.030306","url":null,"abstract":". Polarization diffraction gratings are formed by one-step polarization holographic recording in azopolymer thin films. The evolution of the gratings parameters, such as the modulation of diffraction efficiency and relief depth with regard to different exposure dose is analyzed. Phase-shifting digital holographic microscopy is applied for the measurement of the light-induced polarization diffraction gratings. For the accurate hologram acquisition and reconstruction of the complex amplitude transmitted by the gratings, we performed all-optical (without moving components) phase-shifting implemented within in the imaging system of the digital holographic microscope. The experimental measurement results and theoretical predictions were compared and analyzed. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48835788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Registration of Regeneration in Planarians from Photographic Images 利用摄影图像进行涡虫再生的登记
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-30 DOI: 10.18287/jbpe21.07.030303
K. Tiras, L. Mestetsky, S. Nefedova, N. Lomov
{"title":"Registration of Regeneration in Planarians from Photographic Images","authors":"K. Tiras, L. Mestetsky, S. Nefedova, N. Lomov","doi":"10.18287/jbpe21.07.030303","DOIUrl":"https://doi.org/10.18287/jbpe21.07.030303","url":null,"abstract":". In this study, an approach to constructing a mathematical model for quantifying the dynamics of regeneration of planarian flatworms in biological experiments is considered, based on an analysis of a series of digital microscopic images. A method is proposed to describe the body shape of a planarian using a continuous morphological model, based on the concept of a medial representation of the worm’s silhouette. The silhouette in this case is a polygon approximating the contours of the planarian’s body. The medial representation of the figure includes a medial axis and a radial function that describes the width of the figure relative to the medial axis. We propose a set of morphological criteria for assessing the dynamics of regeneration based on a continuous morphological model and present the results of computational experiments. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46242155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Numerical Modeling of Radiation Focusing by Dielectric Microcylinders with Several Layers 多层介质微柱辐射聚焦的数值模拟
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-30 DOI: 10.18287/jbpe21.07.030304
A. Savelyeva, E. Kozlova
{"title":"Numerical Modeling of Radiation Focusing by Dielectric Microcylinders with Several Layers","authors":"A. Savelyeva, E. Kozlova","doi":"10.18287/jbpe21.07.030304","DOIUrl":"https://doi.org/10.18287/jbpe21.07.030304","url":null,"abstract":"In this paper, the light focusing by dielectric microcylinders with several layers was numerically studied by using the finite element method implemented in COMSOL Multiphysics. Different materials for the top layer were proposed during the research (refractive indices are 1.59, 1.8, 1.9) while the core was proposed from fused silica glass (refractive index is 1.45). It was shown that the dielectric shell allows to increases the maximum intensity of the formed photonic nanojet. Choosing the design of a two-layered microcylinder it is possible to form a compact focal spot (TE-polarization) or increase the length of the produced photonic nanojet. Obtained results were verified by another software package FullWAVE which implements a finite difference time domain method. The simulation results are in good agreement. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41442673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Method for Assessing the Pupil Center Coordinates in Eyetracking with a Free Head Position 一种评估自由头位置眼动中瞳孔中心坐标的方法
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-30 DOI: 10.18287/jbpe21.07.030302
Gennadiy I. Gromilin, N. S. Yakovenko
{"title":"A Method for Assessing the Pupil Center Coordinates in Eyetracking with a Free Head Position","authors":"Gennadiy I. Gromilin, N. S. Yakovenko","doi":"10.18287/jbpe21.07.030302","DOIUrl":"https://doi.org/10.18287/jbpe21.07.030302","url":null,"abstract":". IR-illuminated Eyetracking systems include cornea reflection and pupil center coordinates detection to calculate the ope rator’ s gaze fixation point. When you turn a view of a large angle, some of the frames are blurred, and the coordinates are unreliable. The article describes a method for determining the center of the pupil in the gaze fixation system for operation at an increased camera frame rate. Comparison with known algorithms is given. The algorithm execution average time is about 1.2 ms on a typical office computer by processing images in fragments of the order of 340x240 pixels. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43460445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phthalocyanines Structure Versus Photodynamic Effectiveness towards Pathogenic Microorganisms: Our Recent Experience 酞菁结构对光动力对致病微生物的作用:我们最近的经验
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-25 DOI: 10.18287/jbpe21.07.040202
V. Mantareva, I. Angelov, Meliha Syuleyman, V. Kussovski, I. Eneva, L. Avramov, E. Borisova
{"title":"Phthalocyanines Structure Versus Photodynamic Effectiveness towards Pathogenic Microorganisms: Our Recent Experience","authors":"V. Mantareva, I. Angelov, Meliha Syuleyman, V. Kussovski, I. Eneva, L. Avramov, E. Borisova","doi":"10.18287/jbpe21.07.040202","DOIUrl":"https://doi.org/10.18287/jbpe21.07.040202","url":null,"abstract":". The present review paper aims to summarize our recent experience in research and development of new phthalocyanine complexes and investigations of the main photophysical, photochemical and photobiological properties which are related to antimicrobial photodynamic therapy (aPDT) as alternative method for inactivation of the resistant pathogens. The effect of functionalization of Zn(II) phthalocyanine (ZnPc) with biologically-active natural substances such as amino acids, sugars and steroids was studied in comparison to the basic ZnPc ring molecule. The structural features of the substitution groups were chosen to facilitate the main properties responsible for PDT outcome. For example, the linkage groups of amino acids tyrosine, phenylalanine, lysine and arginine have positive charge in physiological media to the better attachment to bacterial wall and some of them have a good fluorescence for a contribution to the visualization of the infected area. Also, ZnPcs linked to sugars and steroids was expecting to possess receptor specific selectivity. The physicochemical properties of the novel functionalized ZnPcs are presented in respect to their efficiency for a number of pathogenic bacterial and fungal species. Additionally, the complexes of two heavy metal ions such as lutetium(III) (Lu(III)) and tin(IV) (Sn(IV)) were synthesized and evaluated for antimicrobial PDT. These complexes were designed with the same structural skeleton as our previous water-soluble methylpiridyloxy-substituted phthalocyanine complexes with zinc (II), silicon (IV), germanium (IV), indium (III) and gallium (III), all with relatively promising antibacterial efficiency. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48973584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Accuracy of Common Motion Estimators in Wave-Based Optical Coherence Elastography 波基光学相干弹性成像中常用运动估计器的精度
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-21 DOI: 10.18287/jbpe21.07.040303
Justin R. Rippy, Manmohan Singh, S. Aglyamov, K. Larin
{"title":"Accuracy of Common Motion Estimators in Wave-Based Optical Coherence Elastography","authors":"Justin R. Rippy, Manmohan Singh, S. Aglyamov, K. Larin","doi":"10.18287/jbpe21.07.040303","DOIUrl":"https://doi.org/10.18287/jbpe21.07.040303","url":null,"abstract":"Motion estimators are commonly used in shear wave optical coherence elastography to compute small displacements. This work focuses on comparing three motion estimators: Kasai, Loupas, and the vector method. Our results show that the vector method is superior in low-SNR, low-amplitude situations for group velocity calculation and profile reconstruction. © 2021 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47897174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Tissue Spectroscopy and Optical Clearing of Colorectal Mucosa in the Pursuit of New Cancer Diagnostic Approaches 结直肠粘膜的组织光谱学和光学清除在寻求新的癌症诊断方法中的应用
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-08 DOI: 10.18287/JBPE21.07.040302
Luís Fernandes, H. Silva, Inês H Martins, S. Carvalho, I. Carneiro, R. Henrique, V. Tuchin, Luís Manuel Couto Oliveira
{"title":"Tissue Spectroscopy and Optical Clearing of Colorectal Mucosa in the Pursuit of New Cancer Diagnostic Approaches","authors":"Luís Fernandes, H. Silva, Inês H Martins, S. Carvalho, I. Carneiro, R. Henrique, V. Tuchin, Luís Manuel Couto Oliveira","doi":"10.18287/JBPE21.07.040302","DOIUrl":"https://doi.org/10.18287/JBPE21.07.040302","url":null,"abstract":"In this paper we present three studies that demonstrate the applicability of spectroscopy methods and optical clearing treatments in pathology identification and monitoring. In the first study, by obtaining the absorption spectra of human healthy and pathological (adenocarcinoma) colorectal mucosa tissues, it was possible to identify a higher content of a pigment in the diseased tissues. This study also shows that machine learning methods can be used to reach the same differentiated results  in vivo  through diffuse reflectance spectroscopy. In the second study, the combination of collimated transmittance spectroscopy with optical clearing treatments allowed to obtain the diffusion coefficients of glucose in healthy and pathological colorectal mucosa as:  D glucose =5.8x 10 – 7  cm 2 /s and  D glucose =4.4x 10 – 7  cm 2 /s, respectively. This study also demonstrated that the diseased tissues contains about 5% more mobile water than the healthy tissues. The third study was performed to evaluate the protein dissociation mechanism of optical clearing. By treating both healthy and pathological colorectal mucosa tissues with 93%-glycerol, a protein dissociation rate of about 3 times higher was obtained for the pathological mucosa. All the discriminating parameters that result from these studies can be obtained in the  in vivo  situation through diffuse reflectance spectroscopy and further studies to evaluate their values in different stages of cancer progression are of great importance to develop disease monitoring protocols.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47205091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Review of EEG Signal Analysis for Diagnosis of Neurological Disorders using Machine Learning 脑电信号分析在神经系统疾病诊断中的应用综述
Journal of Biomedical Photonics and Engineering Pub Date : 2021-09-07 DOI: 10.18287/10.18287/JBPE21.07.040201
Vandana Joshi, Nirali R. Nanavati
{"title":"A Review of EEG Signal Analysis for Diagnosis of Neurological Disorders using Machine Learning","authors":"Vandana Joshi, Nirali R. Nanavati","doi":"10.18287/10.18287/JBPE21.07.040201","DOIUrl":"https://doi.org/10.18287/10.18287/JBPE21.07.040201","url":null,"abstract":"Neurological disorders are diseases that affect the brain and the central autonomic nervous systems. These disorders take a huge toll on an individual's health and general well-being. After cardiovascular diseases, neurological disorders are the main cause of death. These disorders include epilepsy, Alzheimer ’ s disease, dementia, cerebrovascular diseases including stroke, migraine, Parkinso n ’s disease and numerous other disorders. This manuscript presents a state-of-the-art consolidated review of research on the diagnosis of the three most common neurological disorders using electroencephalogram (EEG) signals with machine learning techniques. The disorders discussed in this manuscript are the more prevalent disorders  like  epilepsy, Attention-deficit/hyperactivity disorder (ADHD), and Alzheimer’s disease. This manuscript helps in understanding the details about EEG signal processing for diagnosis and analysis of neurological disorders along with a discussion of the datasets, limitations, results and research scope of the various techniques.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48807425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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