{"title":"Commentary on the APA Catatonia Resource Document: A Welcome Resource for Clinicians","authors":"Max Fink M.D. , Jonathan Fink Ph.D.","doi":"10.1016/j.jaclp.2025.06.004","DOIUrl":"10.1016/j.jaclp.2025.06.004","url":null,"abstract":"","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 300-301"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin Hoffman M.D., Mary Lynn Dell M.D., Godfrey Pearlson M.D., Benjamin Anderson M.D.
{"title":"Consultation-Liaison Case Conference: Assessing Psychosis in Context of Religious Beliefs","authors":"Justin Hoffman M.D., Mary Lynn Dell M.D., Godfrey Pearlson M.D., Benjamin Anderson M.D.","doi":"10.1016/j.jaclp.2025.02.005","DOIUrl":"10.1016/j.jaclp.2025.02.005","url":null,"abstract":"<div><div>We present the case of a 75-year-old female presenting with an acute mental status change during which she abruptly became nonresponsive and collapsed to the floor. History revealed years of similar episodes in the context of religious beliefs regarding demonic possession and hearing the voices of God and the Devil. Top experts in the field provide perspective and guidance for diagnosing and managing psychiatric illness involving religious themes based on their experience and a review of available literature. Key teaching points include the challenges and limitations of current diagnostic tools, the nature of religious delusions, and engagement strategies for clinicians when dealing with patients exhibiting symptoms overlapping with religious experiences.</div></div>","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 350-357"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David C. Fipps D.O. , Rachel Meyer M.A. , Jeffrey Woods B.A., M.T.S. , Kymberly Watt M.D. , Terry Schneekloth M.D. , Jennifer Gifford M.S. , Bhanu Prakash Kolla M.B.B.S.
{"title":"Corrigendum to “Clinical Utility and Impact of Phosphatidylethanol Testing in Liver Transplantation Evaluations” [Journal of the Academy of Consultation-Liaison Psychiatry 65(2024) 157–166]","authors":"David C. Fipps D.O. , Rachel Meyer M.A. , Jeffrey Woods B.A., M.T.S. , Kymberly Watt M.D. , Terry Schneekloth M.D. , Jennifer Gifford M.S. , Bhanu Prakash Kolla M.B.B.S.","doi":"10.1016/j.jaclp.2025.04.004","DOIUrl":"10.1016/j.jaclp.2025.04.004","url":null,"abstract":"","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Page 374"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne Ruminjo M.D., Parisa R. Kaliush Ph.D., Emily M. Pisetsky Ph.D., Crystal E. Schiller Ph.D., Samantha Meltzer-Brody M.D., Riah Patterson M.D.
{"title":"Zuranolone for Postpartum Depression After Highly Lethal Suicide Attempt: Two Case Illustrations and a Narrative Literature Review","authors":"Anne Ruminjo M.D., Parisa R. Kaliush Ph.D., Emily M. Pisetsky Ph.D., Crystal E. Schiller Ph.D., Samantha Meltzer-Brody M.D., Riah Patterson M.D.","doi":"10.1016/j.jaclp.2025.02.004","DOIUrl":"10.1016/j.jaclp.2025.02.004","url":null,"abstract":"<div><h3>Background</h3><div>In the United States, suicide is one of the leading causes of death in the first year postpartum, possibly accounting for up to 20% of deaths. The Food and Drug Administration recently approved 2 fast-acting medications, brexanolone and zuranolone, for the treatment of postpartum depression (PPD), which shares many clinical features with postpartum suicidality.</div></div><div><h3>Objective</h3><div>Determining the efficacy of zuranolone in the treatment of severe PPD in the context of highly lethal suicide attempts.</div></div><div><h3>Methods</h3><div>We describe 2 illustrative cases of zuranolone treatment of PPD after a gunshot suicide attempt. Following treatment, both women demonstrated a rapid reduction in depressive symptoms and readiness for safe discharge. We also conducted a review of the literature on suicide attempts associated with PPD.</div></div><div><h3>Results</h3><div>Our case series demonstrated that zuranolone may effectively treat PPD with rapid-onset highly lethal suicide attempts.</div></div><div><h3>Conclusions</h3><div>Postpartum suicidality is complex and often emerges rapidly. We advocate for more research on fast-acting novel treatments, such as zuranolone and brexanolone, for PPD and postpartum suicidality.</div></div>","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 341-349"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparative Study of Anticipatory Grief in Caregivers of Patients With Alzheimer's Disease and Hematological Malignancy","authors":"Umut Türk M.D. , Makbule Çiğdem Aydemir M.D. , Erguvan Tuğba Özel-Kizil M.D. , Sinem Civriz Bozdağ M.D.","doi":"10.1016/j.jaclp.2025.04.003","DOIUrl":"10.1016/j.jaclp.2025.04.003","url":null,"abstract":"<div><h3>Background</h3><div><span><span><span>Anticipatory grief (AG) is a common experience that affects caregivers of patients with </span>chronic illnesses, particularly </span>Alzheimer's disease. </span>Cognitive disorders leading to social death produce a greater impact on the relationship, and thus on AG, than physical disorders.</div></div><div><h3>Objective</h3><div><span>The purpose of this study is to examine the prevalence and severity of AG in caregivers of patients with major neurocognitive disorder<span> due to Alzheimer's disease (MNCD-AD) compared to </span></span>hematological malignancies and to identify the characteristics associated with AG.</div></div><div><h3>Methods</h3><div>A total of 132 dyads (patients and their caregivers) completed measures of AG, caregiver burden, anxiety, and depressive symptoms, as well as mental status.</div></div><div><h3>Results</h3><div>The point prevalence of significant AG was similar in the MNCD-AD (57.6%) and hematological malignancy (51.5%) groups. There was no statistically significant difference between the groups in terms of the severity of AG (48.77 ± 17.98 vs 44.18 ± 15.57, respectively). However, the personal sacrifice burden was significantly higher in the MNCD-AD group (<em>P</em> = 0.043). The severity of AG of caregivers is correlated with caregiver burden (r = 0.735), cognitive decline (r = 0.575), and neuropsychiatric symptoms (R = 0.627) of the MNCD-AD patient.</div></div><div><h3>Conclusions</h3><div>The results of the study highlighted that the disease type can influence the AG of caregivers in a qualitative rather than a quantitative manner. Future studies are recommended to consider effects of psychological or interpersonal factors on AG. In addition, psychiatric comorbidities among family caregivers of MNCD-AD patients should be examined.</div></div>","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 320-330"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David E. Karol M.D., Joshua D. Cockroft M.D., Christian J. Pemberton M.D., Caitlin Delong M.D., Jeffrey Welge Ph.D., Elizabeth Tiffany M.D., Christine Wilder M.D.
{"title":"Proactive Addiction Consultation for Hospitalized Patients With Opioid Use Disorder: A Pilot Study","authors":"David E. Karol M.D., Joshua D. Cockroft M.D., Christian J. Pemberton M.D., Caitlin Delong M.D., Jeffrey Welge Ph.D., Elizabeth Tiffany M.D., Christine Wilder M.D.","doi":"10.1016/j.jaclp.2025.04.002","DOIUrl":"10.1016/j.jaclp.2025.04.002","url":null,"abstract":"<div><h3>Background</h3><div>Opioid use disorder (OUD) negatively impacts individuals, communities, and health care systems with significant morbidity and mortality. There is a need for early intervention with hospitalized patients with OUD to improve health outcomes. Proactive consultation-liaison psychiatry, with and without electronic health record tools, is an effective way to reach more patients in need and to improve health services outcomes. The impact of proactive addiction consultation is unknown.</div></div><div><h3>Objective</h3><div>To describe a pilot study examining the effects of proactive addiction consultation on service delivery and clinical outcomes for hospitalized patients with opioid use disorder.</div></div><div><h3>Methods</h3><div>This quasi-randomized, controlled pilot study tested whether, in hospitalized patients with likely OUD, early identification and prompts to initiate consultation resulted in an increased proportion of consultations completed as compared to usual care. Secondary outcomes included initiation of medication for OUD, leaving against medical advice, emergency room utilization, and hospital readmission. An electronic health record-generated daily report was used to identify patients admitted to the hospital in the previous day with diagnoses synonymous with OUD (e.g., opioid abuse and opioid dependence) or often associated with a co-occurring OUD (e.g., bacterial endocarditis and accidental overdose). Individuals confirmed through further chart review as having a high likelihood of OUD were assigned to intervention versus treatment-as-usual in a standardized fashion. The intervention consisted of our research team suggesting an addiction consultation if the patient agreed. Primary teams for the treatment-as-usual participants were not contacted, and consultations were only completed if the primary team independently requested them.</div></div><div><h3>Results</h3><div>Participants randomized to the intervention arm were significantly more likely to receive an addiction consultation (54.8% vs. 16.2%, <em>P</em> < 0.0001). There were no significant differences between the 2 groups in secondary outcomes. Secondary analyses showed that participants who received an addiction consultation (independent of group assignment) were significantly more likely to receive medication for OUD than those who did not (61.2% vs. 29.3%, <em>P</em> < 0.0001).</div></div><div><h3>Conclusions</h3><div>A proactive model suggesting addiction consultation in patients with likely opioid use disorder resulted in an increased proportion of completed consultations as compared to usual care. Addiction consultations were associated with initiation or continuation of medication for OUD, demonstrating the value of addiction consultation services in the hospital. More research is needed to show the potential impact of addiction consultation services on health outcomes.</div></div>","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 311-319"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix Coid M.B.Ch.B., B.Sc. , Jonathan P. Rogers MB BChir, M.Sc. , Aman Saini M.B.B.S. B.Sc. , Mark A. Oldham M.D.
{"title":"Taking an Evidence-Based Approach to 10 Common Myths About Catatonia: An Educational Review","authors":"Felix Coid M.B.Ch.B., B.Sc. , Jonathan P. Rogers MB BChir, M.Sc. , Aman Saini M.B.B.S. B.Sc. , Mark A. Oldham M.D.","doi":"10.1016/j.jaclp.2025.05.008","DOIUrl":"10.1016/j.jaclp.2025.05.008","url":null,"abstract":"<div><div>Catatonia is a serious neuropsychiatric disorder associated with considerable morbidity and mortality. Despite growing interest in the disorder and the field's advancing understanding, a gap between research and clinical practice persists. This is particularly problematic as prompt recognition is essential to optimal management and improving outcomes. We present an educational review of 10 common myths regarding the recognition, etiology, phenotype, and management of catatonia. We address each myth using an evidence-based approach. A few salient considerations include the broad age range affected by catatonia, the fact that patients with catatonia often have preserved awareness of their surroundings, and the importance of using a validated catatonia screening instrument for reliable identification. By addressing these 10 myths, we aim to reduce the gap between evidence and clinical practice to ultimately improve the care and clinical outcomes of people with catatonia.</div></div>","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 358-368"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Judith Allison Restrepo M.D. , Blake L. Rosenbaum M.D. , Daniel Harris M.D. , Thais Gift Pharm.D., BCTXP, BCPS , Oliver Freudenreich M.D.
{"title":"Clozapine in Solid Organ Transplant: A Literature Review and Case Series","authors":"Judith Allison Restrepo M.D. , Blake L. Rosenbaum M.D. , Daniel Harris M.D. , Thais Gift Pharm.D., BCTXP, BCPS , Oliver Freudenreich M.D.","doi":"10.1016/j.jaclp.2025.05.007","DOIUrl":"10.1016/j.jaclp.2025.05.007","url":null,"abstract":"<div><div><span><span>Current experience with the management of clozapine<span><span> in patients needing solid organ transplant (SOT) is sparse. Clozapine is an essential antipsychotic<span> for many patients with treatment-resistant schizophrenia that cannot be replaced by other antipsychotics without the risk of psychotic relapse. However, </span></span>clozapine<span><span> is associated with many side effects, including </span>neutropenia, that may interact with </span></span></span>immunosuppressive therapies during </span>organ transplantation<span><span>. We conducted a literature review of clozapine use during SOT and a retrospective case review using natural language processing of the Partners Research Patient Data Registry to identify individuals over the age of 18 years who had taken clozapine at any time and been evaluated for or undergone SOT—we identified 15 patients who met this criterion. Three patients underwent renal transplantation<span> while remaining on clozapine, and 1 patient started clozapine after renal transplant, all without complication. We have additionally included an illustrative case report to summarize our direct experience of continuing clozapine through </span></span>lung transplant<span>, highlighting the first known case in this population. Finally, we provide clinical guidance for the management of clozapine and associated side effects during SOT. Proactive consultation with psychiatry may avoid abrupt cessation of clozapine, which can result in severe clozapine withdrawal, and increase the number of patients on clozapine considered for SOT.</span></span></div></div>","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 331-340"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam Newlin M.D., Harrison Yu M.D., Mark Mullen M.D.
{"title":"Clozapine Withdrawal Catatonia Successfully Treated With Olanzapine: A Case Report","authors":"Adam Newlin M.D., Harrison Yu M.D., Mark Mullen M.D.","doi":"10.1016/j.jaclp.2025.06.003","DOIUrl":"10.1016/j.jaclp.2025.06.003","url":null,"abstract":"","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 369-370"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does One Size Fit All? Navigating the Tension Between Access and Psychiatric Support in Medical Aid in Dying","authors":"Paul Noufi M.D.","doi":"10.1016/j.jaclp.2025.05.009","DOIUrl":"10.1016/j.jaclp.2025.05.009","url":null,"abstract":"","PeriodicalId":52388,"journal":{"name":"Journal of the Academy of Consultation-Liaison Psychiatry","volume":"66 4","pages":"Pages 371-373"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}