Epilepsy and Paroxysmal Conditions最新文献_第8页

Neurophysiological features in patients with migraine at risk for epilepsy 偏头痛患者癫痫风险的神经生理特征

Epilepsy and Paroxysmal Conditions Pub Date : 2021-10-29 DOI: 10.17749/2077-8333/epi.par.con.2021.064

N. D. Sorokina, A. V. Tsagashek, S. Pertsov, G. V. Selitsky, A. S. Zherdeva

{"title":"Neurophysiological features in patients with migraine at risk for epilepsy","authors":"N. D. Sorokina, A. V. Tsagashek, S. Pertsov, G. V. Selitsky, A. S. Zherdeva","doi":"10.17749/2077-8333/epi.par.con.2021.064","DOIUrl":"https://doi.org/10.17749/2077-8333/epi.par.con.2021.064","url":null,"abstract":"Objective: to study the electrophysiological parameters of brain bioelectric activity and features of the autonomous nervous system assessing heart rate variability, sympathetic skin response, clinical and physiological tests depending on the lateralization of migraine pain syndrome in the right or left brain hemisphere in patients with epileptic electroencephalogram (EEG) signs and migraine.Material and methods. Thirty six patients with aura-free episodic migraine at risk of developing epilepsy and 9 age-matched healthy subjects were examined. All participants underwent EEG, clinical and physiological tests, assessment of heart rate variability and sympathetic skin response.Results. Patients with right-hemisphere migraine headache had signs of activated sympathetic nervous system at baseline level and during exercise, lower baseline EEG epileptiform activity and in provocative tests. In contrast to the subjects of this group, patients of other group featured with a more stable migraine pain syndrome in the left hemisphere tended to dominate with functional activity of the parasympathetic system such as increased trophotropic support during exercise, as well as greater magnitude of baseline epileptiform bioelectric activity and during load tests.Conclusion. Values of heart rate variability in combination with objective results of clinical and physiological assessment of the autonomous nervous system and electrophysiological parameters of brain bioelectric activity are reliable prognostic indicators for varying functional conditions in patients with episodic migraine.","PeriodicalId":52318,"journal":{"name":"Epilepsy and Paroxysmal Conditions","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91231981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness, safety and assessing the results of drug therapy in patients with epilepsy 癫痫患者药物治疗的有效性、安全性及疗效评估

Epilepsy and Paroxysmal Conditions Pub Date : 2021-10-29 DOI: 10.17749/2077-8333/epi.par.con.2021.093

A. Editorial

引用次数: 4

Neuroimaging predictors of structural epilepsy in the COVID-19 catamnesis COVID-19突变中结构性癫痫的神经影像学预测因素

Epilepsy and Paroxysmal Conditions Pub Date : 2021-10-29 DOI: 10.17749/2077-8333/epi.par.con.2021.092

N. E. Maslov, N. V. Yuryeva, E. I. Khamtsova, A. A. Litvinova

{"title":"Neuroimaging predictors of structural epilepsy in the COVID-19 catamnesis","authors":"N. E. Maslov, N. V. Yuryeva, E. I. Khamtsova, A. A. Litvinova","doi":"10.17749/2077-8333/epi.par.con.2021.092","DOIUrl":"https://doi.org/10.17749/2077-8333/epi.par.con.2021.092","url":null,"abstract":"Respiratory system pathology is the most common clinical disorder associated with COVID-19. However, there are also lesions of the immune, cardiovascular, genitourinary, endocrine systems, and digestive tract. In addition, there are numerous reports on infection-related neurological manifestations, which can be divided into 3 groups: central nervous system manifestations (headache and dizziness, stroke, encephalopathy, encephalitis, acute myelitis), lesions of the peripheral nervous system (anosmia, Guillain–Barre syndrome), secondary lesions in the skeletal muscles. Brain damage that occurs during novel coronavirus infection and determines some of the above-mentioned manifestations often account for the development of structural epilepsies. Only a few scarce review articles on neuroimaging features in patients with COVID-19 have been found in Russian research publications.The objective of the review was to collect, analyze and summarize the results of brain magnetic resonance imaging (MRI), currently accumulated worldwide in patients with COVID-19. We present the most common diagnoses based on brain MRI in patients with COVID-19 established by foreign researchers from March 2020 to March 2021, as well as initial attempts to interpret the pathophysiological mechanisms of the changes observed in the brain substance.","PeriodicalId":52318,"journal":{"name":"Epilepsy and Paroxysmal Conditions","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74713311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Igor Dmitrievich Stulin 伊戈尔·德米特里耶维奇·斯图林

Epilepsy and Paroxysmal Conditions Pub Date : 2021-10-29 DOI: 10.17749/2077-8333/epi.par.con.2021.104

A. Editorial

引用次数: 0

Regulatory restrictions on the use of valproate in girls and women of childbearing potential: status update 对有生育潜力的女孩和妇女使用丙戊酸盐的管制限制:最新情况

Epilepsy and Paroxysmal Conditions Pub Date : 2021-10-29 DOI: 10.17749/2077-8333/epi.par.con.2021.101

D. Blinov, E. Akarachkova, V. I. Tsibizova, D. Korabelnikov, N. Pavlova, I. V. Kukes, D. Petrenko

引用次数: 2

Mental development of children from paired mothers with epilepsy: assessing remote teratogenic effects and predictors of developmental disorders 癫痫配对母亲所生儿童的智力发展:评估远程致畸效应和发育障碍的预测因素

Epilepsy and Paroxysmal Conditions Pub Date : 2021-10-29 DOI: 10.17749/2077-8333/epi.par.con.2021.097

N. Mikhailova, A. S. Krasko, G. Odintsova, I. Larina, V. Mikhailov

{"title":"Mental development of children from paired mothers with epilepsy: assessing remote teratogenic effects and predictors of developmental disorders","authors":"N. Mikhailova, A. S. Krasko, G. Odintsova, I. Larina, V. Mikhailov","doi":"10.17749/2077-8333/epi.par.con.2021.097","DOIUrl":"https://doi.org/10.17749/2077-8333/epi.par.con.2021.097","url":null,"abstract":"Objective: to study teratogenic effect – the long-term pregnant mother-taken antiepileptic drugs (AEDs) related consequences on paired child mental, social and intellectual development.Material and methods. There were enrolled 80 subjects: 40 children aged 3–9 years and paired mothers suffering from epilepsy for 3 to 35 years. Thirteen and 27 patients had generalized and focal epilepsy, respectively. Seven mothers were in prolonged remission without taking AEDs, 23 were on monotherapy and 10 were on polytherapy. Child research methods: T. Achenbach's clinical CBCL (The Child Behavior Checklist) scales (for children aged under 5 and 6–18 years), a questionnaire for detecting attention deficit hyperactivity disorder and other behavioral disorders modified by N.N. Zavadenko, Wechsler Intelligence Scale for Children (WISC), Luria batteries of neuropsychological tests adapted by J.M. Glozman (for children aged 3–6 and 7–12 years).Results. Neuropsychological study and assessment of intelligence revealed problems in the development of praxis, speech, gnostic functions and memory, as well as disproportion in the development of verbal and non-verbal structures of intelligence. The most common behavioral disorders in children were impulsivity, distraction, difficulties in controlling and organizing movements. The most affected spheres were praxis (motor awkwardness, fine motor disorders of the hands) and speech.Conclusion. The proposed hypothesis that the teratogenic effect of taking AEDs may result in unevenness or delay in developing mental functions in a child was confirmed.","PeriodicalId":52318,"journal":{"name":"Epilepsy and Paroxysmal Conditions","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77952952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breach-rhythm Breach-rhythm

Epilepsy and Paroxysmal Conditions Pub Date : 2021-07-21 DOI: 10.17749/2077-8333/epi.par.con.2021.055

M. Mironov, S. Burd, N. V. Kukina, Y. Rubleva, O. Kordonskaya, I. V. Senko, A. V. Yurchenko, M. A. Bogomazova, R. Tairova, Kh. A. Dzhabrailova

引用次数: 0

Pharmacological predictors of heart rate and conductivity disorders in juvenile myoclonic epilepsy 青少年肌阵挛性癫痫患者心率和电导率障碍的药理学预测因素

Epilepsy and Paroxysmal Conditions Pub Date : 2021-07-21 DOI: 10.17749/2077-8333/EPI.PAR.CON.2021.051

N. Shnayder, Marina M. Petrova, K. V. Petrov, R. Nasyrova

引用次数: 3

Perampanel in the additional therapy of focal and primary generalized tonic-clonic seizures in children 4–12 years old: clinical data, experience of use and practical recommendations Perampanel在4-12岁儿童局灶性和原发性全身性强直阵挛性癫痫的附加治疗中的应用:临床数据、使用经验和实用建议

Epilepsy and Paroxysmal Conditions Pub Date : 2021-07-21 DOI: 10.17749/2077-8333/EPI.PAR.CON.2021.087

K. Mukhin, E. Belousova, S. Burd, M. V. Barkhatov, N. A. Ermolenko, S. Zyryanov, E. Karpovich, E. Morozova, G. Odintsova

引用次数: 2

Compliance in epileptology. How to change the situation for better 癫痫学的依从性。如何让这种情况变得更好

Epilepsy and Paroxysmal Conditions Pub Date : 2021-07-20 DOI: 10.17749/2077-8333/EPI.PAR.CON.2021.059

N. Maslova, A. A. Litvinova, N. V. Yuryeva, P. S. Kovalev

引用次数: 0