Problemy Osobo Opasnykh Infektsii最新文献

{"title":"Assessment of the Epidemiological Effectiveness of the Temporary Transfer of Schoolchildren to Distance Learning during the Spread of COVID‑19 by the Example of the Saratov Region","authors":"A. A. Zimirova, V. E. Kuklev, V. A. Safronov, E. V. Kuklev, I. N. Vyatkin","doi":"10.21055/0370-1069-2023-3-87-92","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-87-92","url":null,"abstract":"Temporary closure of schools is an effective anti-epidemic measure during periods of rising incidence of acute respiratory viral infections and influenza, which is confirmed by the results of a large number of scientific works. In particular, the effectiveness of this measure consists in reducing the incidence among students. In the context of the spread of COVID‑19 in the Russian Federation, like in many other countries, the temporary transfer of schoolchildren to distance learning has also been repeatedly introduced; however, it remains unclear whether the measure under consideration is effective in relation to the new coronavirus infection. The aim of the study was to assess the epidemiological effectiveness of the temporary transfer of students to distance learning during the spread of COVID‑19 in the Saratov Region. Materials and methods. The analysis was carried out on the basis of statistical data of the Rospotrebnadzor Administration in the Saratov Region on the incidence of COVID‑19 for the period of 2020–2022, as well as materials from published scientific papers. Results and discussion. Analysis of the data on the school closure in 2020 has revealed a decrease in the incidence among schoolchildren (–42.9 %) and an increase in the incidence among people aged 65 years and older (+7.2 %); in 2021, there was a decrease in the incidence among schoolchildren (–15.6 %) and an increase in the indicator value as regards the elderly (+17.8 %); in 2022, another school closure led to an increase in the incidence of COVID‑19 among schoolchildren (+7.8 %) and people over 65 years old (+44.2 %). Based on the results obtained, one can conclude that the measure under consideration is inexpedient due to the fact that the most vulnerable category of the population (persons aged 65 years and older) is actively involved in the epidemic process, which in turn leads to a significant deterioration of the epidemic situation.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID‑19 Pandemic: Effect of Specific and Non-Specific Prevention Measures on the Risk of SARS‑CoV‑2 Infection in Employees of Healthcare Organizations","authors":"I. A. Egorov, S. S. Smirnova, V. A. Mishchenko, I. V. Vyalykh, A. Yu. Markaryan, N. N. Zhuikov, O. Yu. Aver’yanov, V. A. Smirnova, A. N. Bol’shakova, S. Yu. Alferov, A. V. Babanova, A. S. Kilyachina, N. A. Pushkareva, A. V. Semenov","doi":"10.21055/0370-1069-2023-3-80-86","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-80-86","url":null,"abstract":"From the very onset of SARS‑CoV‑2 spreading, active involvement in the COVID‑19 epidemic process made the healthcare professionals (HCPs) a vulnerable group with higher risks of contracting the disease, severe course and fatal outcome. The aim. We aimed at studying the impact of specific and non-specific preventive measures on the risk of SARS‑CoV‑2 infection among the HCPs in a large industrial region settings during the COVID‑19 pandemic. Materials and methods. We analyzed the data obtained using 1 905 questionnaires for the personnel of infectious hospitals for treatment of COVID‑19 patients and non-core healthcare facilities in a large industrial region during the COVID‑19 pandemic, 100 questionnaires on adherence of the employees to hand hygiene and antiseptics, the results of the tests for specific IgG to the SARS‑CoV‑2 nucleocapsid (2 200 samples), as well as the results of assessment of viral and bacterial contamination of the outer surface of the personal protective equipment for infectious hospital staff (108 specimens). Results and discussion. In the course of the study, an effect of failure in the implementation of some specific and non-specific preventive measures on an increase in the incidence of COVID‑19 in various healthcare professionals has been identified. The COVID‑19 pandemic once again emphasized the need to save lives and health of the HCPs as socially significant category of citizens under the spread of pathogens with high epidemic potential, applying a complex of specific and non-specific measures that are not mutually exclusive.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alkyl Sulfatase of Cholera Vibrios","authors":"O. V. Duvanova, O. A. Podoinitsyna, R. V. Pisanov, S. O. Vodop’yanov, A. S. Vodop’yanov, E. S. Shipko, V. D. Kruglikov, O. S. Chemisova, A. K. Noskov","doi":"10.21055/0370-1069-2023-3-73-79","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-73-79","url":null,"abstract":"The aim of the work was to study the structure of the alkyl sulfatase ( asu ) gene in Vibrio cholerae strains of various serogroups, as well as to compare nucleotide and amino acid sequences of alkyl sulfatases using various methods of bioinformatic analysis. Materials and methods. 483 strains of V. cholerae O1, O139 and nonO1/nonO139 serogroups were employed in the work. The search for the gene, its recurrence, and localization was carried out applying the Blast software. The nucleotide and corresponding amino acid sequences of the gene, as well as its structure, were studied using bioinformatic analysis. Sequencing was performed on the MiSeq (Illumina) platform. The enzymatic activity was detected using a medium, confirming the presence/absence of the gene by PCR in vitro and in silico . Results and discussion. Bioinformatic analysis of the nucleotide and corresponding amino acid sequences of the asu gene has been carried out and its structure investigated. Four functional domains have been identified. In the beta-lactamase domain, a conservative amino acid sequence -HAHADH- has been found in all strains of cholera vibrios, which is part of the Zn 2+ binding motif. It has been established that the alkyl sulfatase of cholera vibrios belongs to the family of Zn 2+ -dependent β-lactamases. Blast analysis has revealed the similarity of nucleotide and amino acid sequences of alkyl sulfatases in representatives of V. cholerae O1 and O139 serogroups ( ctxAB + tcpA + ) and representatives of the genera Aeromonas and Pseudomonas , which is in the line with the data of 3D modeling of the amino acid sequence structures of the alkyl sulfatase enzyme in these microorganisms. The bioinformatic analysis of nucleotide and amino acid sequences of alkyl sulfatases in cholera vibrios has showed the conservativeness of these sequences in toxigenic strains and the presence of a number of single mutations in the asu gene in atoxigenic ones. The presence or absence of the asu gene has been established by PCR in vitro and in silico and confirmed by the results obtained using the Blast program. It is demonstrated that the presence/absence of the asu gene correlates with the ability/inability of O139 strains to hydrolyze SDS on the medium. These results can be used in studying mechanisms of cholera vibrios adaptation, persistence and pathogenicity.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135900540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinformatic Analysis of Immunodominant Peptides of Rabies Virus (<i>Rabies lyssavirus, Rhabdoviridae</i>)","authors":"A. G. Galeeva, N. I. Khammadov, M. A. Efimova","doi":"10.21055/0370-1069-2023-3-66-72","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-66-72","url":null,"abstract":"There is a need to develop a new generation of anti-rabies vaccines that provide a protective level of antibodies after a single injection. Prospects for solving this problem are opened by the latest developments in the field of “reverse vaccinology”. The main parameter that determines the effectiveness of recombinant vaccines is the design of the antigen-coding sequence. In this regard, the aim of the work was to conduct a bioinformatic analysis of rabies virus ( Rabies lyssavirus , Rhabdoviridae ) peptides to identify immunogenic epitopes. Materials and methods. Analysis of 5 candidate protein sequences of more than 100 strains and epizootic isolates of the rabies virus was performed using standard in silico prediction methods using Immune Epitope Database (IEDB) (NIH, USA). Results and discussion. As a result of the analysis of primary amino acid sequences, carried out using the most commonly used bioinformatics tools, the number of immunogenic epitopes and the types of immune response detected (T- and B-cell epitopes, class I MHCbinding epitopes) were established for viral proteins: glycoprotein (G), nucleoprotein (N), phosphoprotein (P), matrix protein (M), RNA-dependent RNA polymerase (L). In the amino acid structure of these proteins, N- and O-glycosylation sites, signal peptides, and transmembrane domains were additionally identified. In order to predict the safety and efficacy of these proteins as components of recombinant vaccines, an in silico assessment of their physicochemical properties was carried out. Despite the fact that the predominant number of epitopes is concentrated in the structure of the glycoprotein, the epitopes of other proteins, ranging according to the level of antigenicity and conservatism, may also be of interest as components of preventive drugs or diagnostics. The presented data can be used in the design of the insert during the construction of a candidate virus-vector vaccine or control positive samples in diagnostic methods based on the indication of viral genome fragments.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135654798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Markers of Certain Blood-Borne Viral Infections in Pregnant Women and Their Partners in the Republic of Guinea","authors":"T.A. L. Balde, Yu. V. Ostankova, S. Boumbaly, D. E. Valutite, V. S. Davydenko, A. N. Shchemelev, E. N. Shchemelev, E. B. Zueva, E. V. Anufrieva, E. V. Astapchik, O. V. Arbuzova, V. V. Skvoroda, D. A. Vasil’eva, E. V. Esaulenko, A. V. Semenov, Areg A. Totolian","doi":"10.21055/0370-1069-2023-3-51-58","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-51-58","url":null,"abstract":"The aim of the work was to estimate the prevalence of HIV, HBV and HCV markers among pregnant women and their male partners in the Republic of Guinea. Materials and methods. The material of the study was blood plasma samples from 140 pregnant women living in Kindia prefecture and N’Zerekore prefecture, as well as 60 male partners who reported sexual contact with HIV-infected persons. The samples were examined for the presence of serological (HBsAg, HBeAg, antibodies anti-HBs IgG, anti-HBcore IgG, anti-HBe IgG, anti-HCV IgG, Ag/Ab-HIV) and molecular (HBV DNA, HCV RNA, HIV RNA) markers. Results and discussion. The age of the examined pregnant women ranged from 13 to 55 years and was on average (26.29±9.67) years. The age of men varied from 15 to 60 years, on average – (29.05±11.99) years. When assessing the prevalence of serological markers, antibodies to HCV were detected in 2.14 % cases in women and in 3.33 % cases in men. Antibodies to HIV were found in 6.43 % and 6.67 % women and men, respectively. Serological markers associated with HBV were detected in 80.71 % (HBsAg – 13.57 %) of women and 81.67 % (15 %) of men. In the pregnant women, HCV RNA was not detected, HIV RNA was revealed in 1 case, HBV DNA was identified in 26 cases (18.57 %), including 5 % HBsAg-negative hepatitis B cases. In the men group, HCV RNA and HIV RNA were detected in 3.33 % and 6.67 % cases, respectively. HBV DNA was determined in 16.67 % of men, including latent hepatitis B in one person. A significantly higher incidence of HIV in men compared to women is shown (χ2=3.907 at p<0.05). The relative risk of HIV infection in men is nine times higher than in women: RR=9.333; p=0.0291; 95 % CI: 1.065–81.815 %. Four out of five identified HIV infection cases were co-infected with HBV and/or HCV. There is an obvious need to introduce screening for HIV, HCV, HBV, including latent hepatitis B, into routine laboratory diagnostics during examination of pregnant women and their partners, followed by couples counseling and vaccination against hepatitis B virus.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135040047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Molecular-Genetic Analysis of &lt;i&gt;Francisella tularensis&lt;/i&gt; Strains Isolated in the Rostov Region in 2020 and Genome Sequences of the Strains Collected in Various Regions of the World","authors":"A. S. Vodop’yanov, R. V. Pisanov, S. O. Vodop’yanov, M. V. Tsimbalistova, N. L. Pichurina, V. M. Sorokin, N. V. Pavlovich, A. K. Noskov","doi":"10.21055/0370-1069-2023-3-59-65","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-59-65","url":null,"abstract":"Six cultures of tularemia microbe from fallen and captured live animals were isolated during epizootiological monitoring in the steppe focus in the south-east of the Rostov Region in 2020 against the background of extensive epizootics in the populations of the common vole Microtus arvalis obscurus and the public vole Microtus socialis . The aim of the work was to develop an SNP-typing scheme and to conduct a comparative study of the phylogenetic relations between Francisella tularensis strains isolated in the Rostov Region (2020) and strains from other regions. Materials and methods. Genome-wide sequencing was performed on the MiSeq Illumina platform. The author’s software GeneExpert, PrimerM and VirtualPCR, written in the Java programming language, were used for the analysis. Results and discussion. The strains of tularemia agent, isolated on the territory of the Rostov Region in 2020, can be allocated to two different clusters. It is established that two strains of tularemia pathogen (F0884 and F0889) isolated in Turkey are genetically close to some isolates circulating in the Rostov Region. A unique INDEL marker characteristic of this group of strains has been identified. The comparison of our proposed typing scheme with the scheme of “canonical” SNPs has showed a fairly good consistency and convergence of results within large clusters, meanwhile using a set of 6626 SNPs allows for differentiating the strains within one canSNP type. It is revealed that the vaccine strain has a common canSNP type with clinical and natural strains. A set of SNP markers has been selected for comparative analysis. A new INDEL marker that enables intraspecific typing of F. tularensis has been discovered and the possibility of its application in vitro and in silico has been comfirmed.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135039894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epizootiological and Epidemiological Situation on Leptospirosis in the Russian Federation over the Period of 2013–2022 and the Forecast for 2023","authors":"D. V. Trankvilevsky, E. Yu. Kiseleva, V. M. Korzun, N. V. Breneva, Yu. A. Verzhutskaya, I. D. Zarva, O. N. Skudareva, S. V. Balakhonov","doi":"10.21055/0370-1069-2023-3-43-50","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-43-50","url":null,"abstract":"The aim of the work was to analyze the epizootic and epidemiological situation on leptospirosis in the territory of the Russian Federation in 2013–2022 and to forecast its development in 2023. The long-term dynamics of leptospirosis incidence in the Russian Federation tends to decrease. Cases were registered in 58 constituent entities of the Russian Federation, in all federal districts. The highest incidence rates were noted in the North-Western Federal District. When studying the material from small mammals using bacteriological, immunological and molecular-biological methods, Leptospira circulation was detected in 52 entities of the Russian Federation, in all federal districts. In 2023, sporadic cases of infection are to be expected in the territories of the North-Western Federal District, the Central Federal District, and the Southern Federal District; imported cases of infection from countries with subequatorial and equatorial climates are not excluded.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135295820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spread of the Sindbis Virus in Fennoscandia","authors":"L. V. Rubis","doi":"10.21055/0370-1069-2023-3-33-42","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-33-42","url":null,"abstract":"In the second half of the last century, a persistent focus of the disease caused by Sindbis virus was formed on the territory of Fennoscandia. In different countries, the disease is called Pogosta disease, Ockelbo disease and Karelian fever. The highest incidence rate is in Finland, where diseases are recorded annually, ranging from sporadic cases to large outbreaks with hundreds of patients. In other Scandinavian countries and in Russia, isolated cases of infection are currently being detected. The data on registered incidence and the results of seroepidemiological studies indicate an unequal dissemination of the infection in Fennoscandia, the causes of which need to be investigated. The review presents updated information on the pathogen, its distribution among the population and in the biocenosis of Fennoscandia, clinical features, diagnostics and epidemiological characteristics of the incidence.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135295822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usutu Virus (&lt;i&gt;Flaviviridae, Orthoflavivirus&lt;/i&gt;). Potential Danger and Possibility of Spread on the Territory of the Russian Federation","authors":"E. V. Naidenova, K. S. Zakharov, K. D. Blinova, I. G. Shvidenko, A. V. Boiko, S. A. Shcherbakova","doi":"10.21055/0370-1069-2023-3-22-32","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-22-32","url":null,"abstract":"In recent decades, an increase in the number of cases of detection of the Usutu virus (Usutu, USUV, Orthoflavivirus usutuense ) (family Flaviviridae , genus Orthoflavivirus ) has caused great concern among medical professionals, including virologists and specialists in infectious diseases, especially since its appearance in Europe, where the pathogen caused mass birds die-off, and annually registered human cases. This review provides information about the structure of the virus and its genetic variants, geographical distribution and features of circulation in Europe and Africa, the methods and principles used to indicate and identify this pathogen, as well as the main symptoms of the disease it causes. An assessment of the environmental prerequisites for the occurrence of outbreaks of the disease caused by the Usutu virus on the territory of the Russian Federation was also carried out.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135295821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Automated Information System “Perimeter” is a Tool for the Modernization of Information and Technical Support of Sanitary and Quarantine Control","authors":"A. Yu. Popova, E. B. Ezhlova, V. Yu. Smolensky, A. N. Letyushev, A. A. Treskin, A. V. Ivanova, V. A. Safronov, A. A. Zubova, I. G. Karnaukhov, V. P. Toporkov, S. A. Shcherbakova, V. V. Kutyrev","doi":"10.21055/0370-1069-2023-3-6-14","DOIUrl":"https://doi.org/10.21055/0370-1069-2023-3-6-14","url":null,"abstract":"Sanitary and quarantine control (SQC) at the state border of the Russian Federation is the first barrier to the importation and subsequent spread of diseases on the territory of the country. Every year the number of registered outbreaks of infectious diseases in the countries of the world increases, which entails an increase in published information, some of which is unreliable and requires verification. At the same time, against the background of the development of international tourism, increase in passenger traffic, the risk of infectious diseases importation into the territory of Russia rises manifold, which creates the need for modernization of information and technical support of the SQC. In connection with the above, the aim of the work was to develop a scientifically substantiated system of informatization and digitalization of SQC, which resulted in the introduction of an automated risk assessment system as regards importation of dangerous infectious diseases (AIS “Perimeter”) at all sanitary-quarantine checkpoints (SQP). Materials and methods. The information system was created using the following software platforms: Laravel, VueJs. The official websites of the Ministries of Health of the respective countries, data from the official regional websites of WHO, regional centers for disease control and prevention (CDC), and data from the ProMED-mail system were used as sources of information on infectious morbidity in the countries of the world . Results and discussion. Implementation of AIS “Perimeter” has brought about the maximum possible efficiency in the targeted informing of SQP officials about the current epidemiological situation in the countries of the world; an effective tool for monitoring the situation at the federal level in real-time mode. It facilitates the work of SQP, staff related to conducting standard operational procedures, due to considerable decrease in the volume of routine activities to keep records. The proposed in the AIS expert risk assessment as regards importation of infectious diseases allows SQP employees, based on reliable information, to make timely decisions on the need to conduct SQC and exclude erroneous actions in the essential set of measures within the framework of SQC implementation, while minimizing subjectivity with respect to decision making.","PeriodicalId":52264,"journal":{"name":"Problemy Osobo Opasnykh Infektsii","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135470730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}