The Psychiatric quarterly最新文献

筛选
英文 中文
Traumatic Childbirth Experiences and their Association with Postpartum Psychiatric Disorders: A Systematic Review. 创伤性分娩经历及其与产后精神障碍的关系:一项系统综述。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-09-01 Epub Date: 2025-07-08 DOI: 10.1007/s11126-025-10180-4
Valentina Baldini, Martina Gnazzo, Diana De Ronchi, Marco Carotenuto, Maria Carmela Pera, Andrea Fiorillo
{"title":"Traumatic Childbirth Experiences and their Association with Postpartum Psychiatric Disorders: A Systematic Review.","authors":"Valentina Baldini, Martina Gnazzo, Diana De Ronchi, Marco Carotenuto, Maria Carmela Pera, Andrea Fiorillo","doi":"10.1007/s11126-025-10180-4","DOIUrl":"10.1007/s11126-025-10180-4","url":null,"abstract":"<p><p>Traumatic childbirth experiences, characterized by intense fear, helplessness, or loss of control during labor or delivery, may increase the risk of postpartum psychiatric disorders. Events such as emergency cesarean sections, preterm births, and neonatal intensive care unit admissions have been associated with elevated psychological distress. This systematic review aimed to synthesize current evidence on the association between traumatic childbirth experiences and postpartum psychiatric disorders, including depression, post-traumatic stress disorder, and anxiety. A systematic search of PubMed, Web of Science, EMBASE, and PsycINFO databases was conducted. Two reviewers independently performed study selection, data extraction, and quality assessment using the Newcastle-Ottawa Scale. Eighteen studies involving 1,892 women were included. Rates of postpartum depression and post-traumatic stress disorder were consistently higher among women who experienced emergency cesarean sections compared to vaginal deliveries. Considerable heterogeneity was observed across study designs, populations, and assessment methods. This review suggests a consistent association between traumatic childbirth experiences and postpartum psychiatric disorders. Further longitudinal research using standardized methodologies is needed to clarify causal mechanisms and inform the development of effective trauma-informed interventions to support maternal mental health.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":"805-817"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinguishing Patient Profiles of Suicidal Ideation and Behavior: The Influence of Repetitive Negative Thinking, Internal and External Entrapment, and Defeat within the Integrated Motivational-Volitional Model in a Suicide Prevention Program. 区分自杀意念和行为的患者概况:重复消极思维的影响,内部和外部陷阱,以及在自杀预防计划中综合动机-意志模型中的失败。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-09-01 Epub Date: 2025-07-17 DOI: 10.1007/s11126-025-10187-x
María Aliño-Dies, Daniel Sánchez-Reolid, Marta Monferrer, María J Montes, Antonio Fernández-Caballero, Patricia Fernández-Sotos, Jorge J Ricarte
{"title":"Distinguishing Patient Profiles of Suicidal Ideation and Behavior: The Influence of Repetitive Negative Thinking, Internal and External Entrapment, and Defeat within the Integrated Motivational-Volitional Model in a Suicide Prevention Program.","authors":"María Aliño-Dies, Daniel Sánchez-Reolid, Marta Monferrer, María J Montes, Antonio Fernández-Caballero, Patricia Fernández-Sotos, Jorge J Ricarte","doi":"10.1007/s11126-025-10187-x","DOIUrl":"10.1007/s11126-025-10187-x","url":null,"abstract":"<p><p>This study investigates the cognitive mechanisms that facilitate the transition from suicidal ideation (SI) to suicidal behavior (SB), focusing on the interplay of repetitive negative thinking (RNT), feelings of defeat, and perceptions of entrapment, both internal and external, within the framework of the Integrated Motivational-Volitional (IMV) Model. We aimed to predict group membership and identify predictors between those exhibiting SI (n = 56) and those with SB (n = 37), with particular attention to the aforementioned cognitive variables. An observational, analytical, cross-sectional study was conducted with a clinical sample from a suicide prevention program in Spain, in which patients were assessed during suicidal crises. Results revealed a moderate positive correlation between RNT and both entrapment types, as well as feelings of defeat, across both patient groups, with stronger correlations observed for internal entrapment, particularly in the SB group. The binary logistic regression did not yield conclusive results regarding distinguishing between patient groups in terms of cognitive variables, consistent with existing literature, which may reflect the complexity of the factors influencing suicidal ideation and behavior. Female gender and prior emergency department visits were significant factors distinguishing the SI from the SB group, and female gender was the only variable that proved to be a key predictor of patient type (SI specifically), with an OR = 13.397 (p = 0.005). Our findings highlight the implication of integrating cognitive-behavioral interventions that target repetitive negative thinking, feelings of defeat, and entrapment into specific suicide prevention programs. More specifically, preventive clinical strategies should prioritize high-risk populations such as young women with a history of psychiatric emergencies. To effectively address the needs of this population, protocols could be implemented that include support groups, personalized follow-up systems, and training for mental health professionals on gender-sensitive approaches to enhance their mental well-being.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":"913-933"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Cultural Face of Physical, Emotional, and Social Resilience: Turkish Validation of the Essential Resilience Scale (ERS). 身体、情感和社会弹性的文化面貌:土耳其人对基本弹性量表(ERS)的验证。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-27 DOI: 10.1007/s11126-026-10308-0
Tuğba Akbalık, Yıldız Bilge
{"title":"The Cultural Face of Physical, Emotional, and Social Resilience: Turkish Validation of the Essential Resilience Scale (ERS).","authors":"Tuğba Akbalık, Yıldız Bilge","doi":"10.1007/s11126-026-10308-0","DOIUrl":"https://doi.org/10.1007/s11126-026-10308-0","url":null,"abstract":"<p><p>This study aims to adapt The Essential Resilience Scale (ERS), which assesses resilience within the framework of anticipation, flexibility, and bounce back mechanisms and consists of three sub-dimensions: physical, emotional and social resilience, into Turkish and to evaluate its psychometric properties. The sample consists of a total of 327 participants, 267 females (81.7%) and 58 males (17.7%) between the ages of 18-70 (M = 27.08, SD = 9.73). Test-retest correlation, corrected item-total correlation and Cronbach's alpha internal consistency coefficients were calculated to test reliability. The construct validity of the ERS was evaluated with first-order and second-order confirmatory factor analysis (CFA). For the convergent validity, Brief Resilience Scale (BRS), Warwick-Edinburgh Mental Well-being Scale (WEMWBS), and Depression Anxiety Stress Scale-21 (DASS-21) was performed with the ERS. The Cronbach's alpha internal consistency coefficients ranged from 0.61 to 0.82, while the test-retest correlations varied between 0.64 and 0.81. Both first order and second order CFA supported the three-dimensional structure of the ERS, with acceptable-to-good fit of data. In the context of convergent validity analysis, correlation coefficients between the ERS-total resilience and the WEMWBS, BRS, and DASS-21 scales varied between - 0.24 and 0.67. As a result, the findings provide support for the validity and reliability of the Turkish version of the ERS that is suitable for using in academic and clinical researches.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148842783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal association between concurrent changes in social support and mental health symptoms among low-income U.S. veterans: a 2-year follow-up study. 低收入美国退伍军人社会支持与心理健康症状并发变化的纵向关联:一项为期2年的随访研究
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-27 DOI: 10.1007/s11126-026-10310-6
Jack Tsai, Bijeta Pradhan, Md Faruk Hossain, Vahed Maroufy
{"title":"Longitudinal association between concurrent changes in social support and mental health symptoms among low-income U.S. veterans: a 2-year follow-up study.","authors":"Jack Tsai, Bijeta Pradhan, Md Faruk Hossain, Vahed Maroufy","doi":"10.1007/s11126-026-10310-6","DOIUrl":"https://doi.org/10.1007/s11126-026-10310-6","url":null,"abstract":"<p><p>Social support is known to be able to buffer against psychological stressors, but further study is needed on how different types of social support and mental health change together over time, especially in special populations like U.S. veterans. Social support can also be divided into four types: Emotional Support/Informational Support, Positive Social Interaction, Tangible Support, and Affectionate Support. Using a longitudinal, nationally representative sample of 735 low-income U.S. veterans over 2 years (2021-2023), this study examined the association between changes in these four types of social support in relation to changes in symptoms of major depression, generalized anxiety disorder, posttraumatic stress disorder, alcohol use disorder, and overall physical and mental health-related quality of life. The results found that decreased Emotional/Informational Support, Positive Social Interaction, and Tangible Support were all associated with decreases in depressive symptoms. In contrast, changes in the four types of social support were not associated with changes in other mental health symptoms. Together, these findings indicate the important role that social support may play, specifically in major depression, and underlines the importance of helping low-income U.S. veterans develop strong social networks.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148842765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Negative Mood Regulation Expectancies, Affect and Suicidal Ideation: A Moderated Mediation Analysis. 负性情绪调节预期、情绪与自杀意念:一个有调节的中介分析。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-19 DOI: 10.1007/s11126-026-10301-7
Anabel Söhlemann, Karen Wetherall, Rory C O'Connor, Ambrose J Melson
{"title":"Correction: Negative Mood Regulation Expectancies, Affect and Suicidal Ideation: A Moderated Mediation Analysis.","authors":"Anabel Söhlemann, Karen Wetherall, Rory C O'Connor, Ambrose J Melson","doi":"10.1007/s11126-026-10301-7","DOIUrl":"https://doi.org/10.1007/s11126-026-10301-7","url":null,"abstract":"","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Optimism-Pessimism in the Relationship Between Perceived Social Support and Developmental Problem Areas Among Adolescents in Türkiye. 乐观-悲观在中国青少年感知社会支持与发展问题领域关系中的作用。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-19 DOI: 10.1007/s11126-026-10300-8
Çiğdem Aytekin, Fatma Öncel Kılınç, Raziye Yüksel Doğan
{"title":"The Role of Optimism-Pessimism in the Relationship Between Perceived Social Support and Developmental Problem Areas Among Adolescents in Türkiye.","authors":"Çiğdem Aytekin, Fatma Öncel Kılınç, Raziye Yüksel Doğan","doi":"10.1007/s11126-026-10300-8","DOIUrl":"https://doi.org/10.1007/s11126-026-10300-8","url":null,"abstract":"<p><p>In this study, it was aimed to examine the role of optimistic-pessimistic thinking style in the relationship between social support perceived from family, peers and teachers in adolescence and developmental problems that may be frequently encountered in adolescence. This cross-sectional study, conducted in Türkiye, employed a correlational research design with a convenience sample of 475 adolescents (241 girls and 234 boys) aged 14-17. Participants completed the Optimism-Pessimism Scale for Adolescents, the Social Support Appraisals Scale, and the Developmental Problem Areas Scale. The correlation analysis results showed that there were significant relationships between perceived social support from family, peers and teachers, optimistic-pessimistic thinking style and developmental problems. The mediation analysis results indicated that optimism and pessimism mediated the relationship between perceived social support and developmental problems, showing both partial and full mediation patterns depending on the source of social support. Taken together, the findings suggest that social support received from various sources in adolescence may facilitate coping with developmental problems by increasing adolescents' optimistic thinking style or decreasing their pessimistic thinking style. The results were discussed in the light of the literature and some suggestions based on the findings were presented.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-Care and Illness Perception in Inflammatory Bowel Disease: Identifying Adaptive and Maladaptive Profiles Through Person-Centered Analysis. 炎症性肠病的自我保健和疾病感知:通过以人为中心的分析识别适应和不适应概况。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-18 DOI: 10.1007/s11126-026-10306-2
Daniele Napolitano, Mattia Bozzetti, Alessio Lo Cascio, Nicoletta Orgiana, Simone Parello, Antonio Maria D'Onofrio, Gianna Autullo, Giovanni Camardese, Marianna Mazza, Giuseppe Marano, Federica Di Vincenzo, Karen Kamp, Antonio Gasbarrini, Franco Scaldaferri
{"title":"Self-Care and Illness Perception in Inflammatory Bowel Disease: Identifying Adaptive and Maladaptive Profiles Through Person-Centered Analysis.","authors":"Daniele Napolitano, Mattia Bozzetti, Alessio Lo Cascio, Nicoletta Orgiana, Simone Parello, Antonio Maria D'Onofrio, Gianna Autullo, Giovanni Camardese, Marianna Mazza, Giuseppe Marano, Federica Di Vincenzo, Karen Kamp, Antonio Gasbarrini, Franco Scaldaferri","doi":"10.1007/s11126-026-10306-2","DOIUrl":"https://doi.org/10.1007/s11126-026-10306-2","url":null,"abstract":"<p><p>Self-care and illness perception are key determinants of adaptation to inflammatory bowel disease (IBD), but their relationship may be heterogeneous and poorly captured by average-level associations. This multicenter cross-sectional study examined whether self-care behaviors were associated with illness perception and explored whether distinct patient profiles could be identified from their combined behavioral and cognitive-emotional patterns. Between April and June 2024, adult patients were recruited consecutively from nine Italian IBD units and completed validated measures of self-care, illness perception, self-care self-efficacy, and psychological distress. Structural equation modeling was used to test the association between self-care domains and illness perception, followed by unsupervised cluster analysis. Among 450 participants with complete data, the structural equation model showed satisfactory fit, but no self-care domain was significantly associated with illness perception. Four clinically interpretable profiles emerged: Engaged Copers, Overwhelmed and Passive, Detached and Vulnerable, and Minimizers with Functional Engagement. The profiles differed markedly in illness perception and self-care behaviours, with large effect sizes, whereas anxiety and self-care self-efficacy showed statistically significant but small between-profile differences. No statistically significant omnibus differences were observed in generational distribution, exercise habits, or disease activity. These findings suggest that self-care and illness perception are not related through a simple linear association. Person-centered profiling may support tailored self-management education and psychological assessment in routine IBD care.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Cognitively Enriched Handball Training on Behavioral Symptoms, Working Memory, and Motor Competence in Girls with ADHD: A Randomized Controlled Trial. 认知强化手球训练对ADHD女孩行为症状、工作记忆和运动能力的影响:一项随机对照试验
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-14 DOI: 10.1007/s11126-026-10305-3
Maryam Kavyani, Fatemeh Asadi Toosi, Alireza Farsi, Fatemeh Keshvari
{"title":"Effects of Cognitively Enriched Handball Training on Behavioral Symptoms, Working Memory, and Motor Competence in Girls with ADHD: A Randomized Controlled Trial.","authors":"Maryam Kavyani, Fatemeh Asadi Toosi, Alireza Farsi, Fatemeh Keshvari","doi":"10.1007/s11126-026-10305-3","DOIUrl":"https://doi.org/10.1007/s11126-026-10305-3","url":null,"abstract":"<p><p>Attention-deficit/hyperactivity disorder (ADHD) is associated with behavioral, cognitive, and motor impairments that may negatively affect children's academic and social functioning. The present study examined the effects of cognitively enriched handball training and conventional handball training on behavioral symptoms, working memory, and motor competence in girls with ADHD. A total of 45 girls aged 7-9 years with ADHD participated in this parallel-group randomized controlled trial and were randomly assigned to cognitively enriched handball training (n = 15), conventional handball training (n = 15), or a control condition (n = 15). Behavioral symptoms, working memory, and motor competence were assessed using the Child Behavior Checklist (CBCL), the Wechsler Digit Span Test, and the MOBAK-3, respectively. Data were analyzed using multivariate analysis of covariance (MANCOVA). After controlling for baseline scores, the multivariate group effect was significant (partial η² = 0.56), with large omnibus effects for behavioral symptoms (partial η² = 0.82), working memory (partial η² = 0.66), and motor competence (partial η² = 0.65). Both exercise interventions significantly improved behavioral symptoms, working memory, and motor competence compared with the control group (p < .05). Furthermore, cognitively enriched handball training produced significantly greater improvements in behavioral symptoms and motor competence than conventional handball training (p < .05), whereas no significant difference was observed between the two exercise groups for working memory. These findings suggest that cognitively enriched handball training may provide short-term complementary benefits for behavioral regulation and motor competence in girls with ADHD. However, the small sample size and absence of follow-up assessments warrant cautious interpretation and limit conclusions regarding the generalizability and long-term maintenance of these effects.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimal 24-Hour Sleep Duration and Depression Risk in Chinese Middle-Aged and Elderly: A Machine Learning and RCS Analysis of Nonlinear Associations. 中国中老年人最佳24小时睡眠时间与抑郁风险:非线性关联的机器学习和RCS分析。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-13 DOI: 10.1007/s11126-026-10307-1
Zhuo Chen, Taoyang Cai, S K Kot-Cheung, Yanru Liu
{"title":"Optimal 24-Hour Sleep Duration and Depression Risk in Chinese Middle-Aged and Elderly: A Machine Learning and RCS Analysis of Nonlinear Associations.","authors":"Zhuo Chen, Taoyang Cai, S K Kot-Cheung, Yanru Liu","doi":"10.1007/s11126-026-10307-1","DOIUrl":"https://doi.org/10.1007/s11126-026-10307-1","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the relationship between sleep (nocturnal sleep and total 24-hour sleep) and depressive symptoms in middle-aged and elderly people using data from the China Health and Retirement Longitudinal Study (CHARLS).</p><p><strong>Study design: </strong>Cross-sectional study.</p><p><strong>Methods: </strong>A total of 13,718 middle-aged and elderly people aged 45 and above from the China Health and Retirement Longitudinal Study (CHARLS 2020) were included. A multivariate logistic regression model was used to analyze the correlation between sleep and depressive symptoms, and a random forest model was used to rank the importance of variables. Furthermore, the nonlinear relationship between sleep duration and depressive symptoms risk was fitted using a restricted cubic spline (RCS) model.</p><p><strong>Results: </strong>Compared with the group with 24-hour sleep duration of > 7 to ≤ 9 h, the adjusted odds ratio (OR) for depressive symptoms in the group with 24-hour sleep duration of ≤ 7 h (OR = 1.649) and > 9 h (OR = 1.166) was higher. Random forest results showed that total 24-hour sleep ranked above average among variables affecting depressive symptoms. The RCS curve showed that a total 24-hour sleep time of > 7 to ≤ 9 h was associated with the lowest adjusted odds for depressive symptoms.</p><p><strong>Conclusions: </strong>There is a significant correlation between sleep duration and depressive symptoms in middle-aged and elderly people. Those who slept > 7 to ≤ 9 h per night had a lower incidence of depressive symptoms, and total 24-hour sleep of > 7 to ≤ 9 h showed a stronger OR value. Life satisfaction also emerged as an important factor influencing depressive symptoms.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methodological Concerns in a Recently Published Systematic Review and Meta-Analysis of Xanomeline-Trospium in Schizophrenia : Re: Azargoonjahromi A, Nasiri H. Efficacy and Safety of KarXT (Xanomeline-Trospium; Cobenfy™) in Schizophrenia: A Systematic and Meta-Analysis Review of Randomized Controlled Trials. Psychiatric Quarterly. 2025. https://doi.org/10.1007/s11126-025-10226-7. Re: Azargoonjahromi a, Nasiri H. KarXT (Xanomeline-Trospium; Cobenfy™)治疗精神分裂症的疗效和安全性:一项随机对照试验的系统和荟萃分析综述。精神病学季刊,2025。https://doi.org/10.1007/s11126 - 025 - 10226 - 7。
IF 2.9
The Psychiatric quarterly Pub Date : 2026-08-03 DOI: 10.1007/s11126-026-10303-5
Anmol Dhale, Darshankumar Dharaiya
{"title":"Methodological Concerns in a Recently Published Systematic Review and Meta-Analysis of Xanomeline-Trospium in Schizophrenia : Re: Azargoonjahromi A, Nasiri H. Efficacy and Safety of KarXT (Xanomeline-Trospium; Cobenfy™) in Schizophrenia: A Systematic and Meta-Analysis Review of Randomized Controlled Trials. Psychiatric Quarterly. 2025. https://doi.org/10.1007/s11126-025-10226-7.","authors":"Anmol Dhale, Darshankumar Dharaiya","doi":"10.1007/s11126-026-10303-5","DOIUrl":"https://doi.org/10.1007/s11126-026-10303-5","url":null,"abstract":"<p><p>This letter addresses significant methodological limitations in a recently published systematic review and meta-analysis evaluating the efficacy and safety of xanomeline-trospium (KarXT) in schizophrenia. A critical unit-of-analysis error is identified in the original review's Table 1, wherein multiple secondary and post hoc publications from a single randomized controlled trial (EMERGENT-1) were extracted and treated as completely independent studies. This unit-of-analysis error violates statistical independence assumptions and likely contributed to an implausible pooled effect size; however, additional discrepancies in data extraction or effect-size calculation may also have influenced the pooled estimate (d = 0.08) that sharply contradicts individual trial data. Additionally, the review lacks registered protocol details, structured risk-of-bias reporting, and safety outcome pooling. Readers and clinicians are cautioned against interpreting the pooled conclusions in isolation.</p>","PeriodicalId":520814,"journal":{"name":"The Psychiatric quarterly","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书