The Journal of adolescent health : official publication of the Society for Adolescent Medicine最新文献

{"title":"Smaller Subcortical Volume in Reward Processing Regions Precedes Weight Gain in Youth With High Financial Adversity: Findings From the Adolescent Brain Cognitive Development Study.","authors":"Shana Adise, Christopher J Machle, Kevin P Myers, Jonatan Ottino-González, Joshua Millstein, Michael I Goran, Elizabeth R Sowell","doi":"10.1016/j.jadohealth.2025.03.019","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.019","url":null,"abstract":"<p><strong>Purpose: </strong>Financial adversity has been associated with altered subcortical neurodevelopment and obesity risk. However, no studies have examined these relationships in tandem. Food intake is influenced by the subcortex; thus, we examined whether financial adversity moderated bidirectional relationships between neurodevelopment and body mass index (BMI) in early adolescence.</p><p><strong>Methods: </strong>Data were gathered from the Adolescent Brain Cognitive Development Study (n_T0 = 3,606 [9/10 years, 100% healthy weight, 50.8% male; 71.4% White, 15.6% Latino, 869 youth with financial adversity]; n_T2 = 2,395 [11/12 years, 11.2% overweight/obese]; no siblings). Financial adversity was assessed on a seven-item binary response questionnaire. Population-level effects of Financial Adversity∗Subcortical Volume (8 bilateral regions)∗Time on BMI were examined with mixed models, while individual differences and temporal precedence of cross-domain couples were examined with a Multiple Indicator Bivariate Latent Change Score model.</p><p><strong>Results: </strong>By 11/12 years, higher financial adversity was associated with a greater increase in BMI (i.e., weight gain) and a negative association with volume in the bilateral accumbens, caudate, and right pallidum. The Bivariate Latent Change Score model showed that smaller subcortical volume preceded and predicted greater weight gain among youth with three or more financial adverse experiences.</p><p><strong>Discussion: </strong>Our findings suggest that financial adversity may alter subcortical development regions associated with reward processing and food intake control, and potentially contribute to greater weight gain (i.e., increased BMI trajectory over a 2-year period). By elucidating these mechanisms within the natural progression of weight gain, we highlight a potential neurosocioeconomic risk factor for obesity development.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National Trends of Suicidal Thoughts and Behaviors Among Asian American Young Adults Between 2008 and 2019: The Intersection of Sex and Sexual Identity.","authors":"Hyeouk Chris Hahm, Seungbin Oh, Brian TaeHyuk Keum, Cindy H Liu, Madison Kitchen, Julia Starrett, Michael Tang, Thomas Joiner","doi":"10.1016/j.jadohealth.2025.03.009","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.009","url":null,"abstract":"<p><strong>Purpose: </strong>There is insufficient literature examining the intersections among sex, sexual orientation, and suicidal thoughts and behaviors (STBs) among Asian American (AA) young adults.</p><p><strong>Methods: </strong>Data from the National Survey of Drug Use and Health ( 2008-2019), focusing on AAs aged 18-25 (n = 8,600), were analyzed, with sexual identity questions included in the 2015-2019 data. A total of 268 (7.45%_wt) respondents identified themselves as lesbian, gay, or bisexual. Joinpoint regression analysis was used to examine trends over time, and predictive modeling was used to assess the impact of intersecting identities on STBs. Logistic regression was used to test the association between STBs and sex, sexual orientation, and the intersection of sex and sexual orientation.</p><p><strong>Results: </strong>Trends for STBs showed an upward trajectory. Joinpoint regression analysis revealed a significant increase in suicidal thoughts, plans, and attempts, with annual percentage changes of 3.34% per year (p = .03), 7.45% per year (p = .002), and 7.52% per year (p = .04), respectively. There was a clear disparity based on sexual identity: while trends for STBs among heterosexuals were flat across all STBs, for sexual minorities, the annual percentage changes for suicidal thoughts, plans, and attempts were 11.27% (p = .43), 42.4% (p = .06), and 64.9% (p = .23), respectively, although these increases were not statistically significant.</p><p><strong>Discussion: </strong>It is crucial to develop effective suicide prevention strategies or address mental health disparities for AA young adults while accounting for the intersection of sex and sexual minority status.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Adolescent Births in Mexico in the Context of a National Adolescent Pregnancy Prevention Program, 2008-2019.","authors":"Evelyn Fuentes-Rivera, Raffaela Schiavon, Blair G Darney","doi":"10.1016/j.jadohealth.2025.03.021","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.021","url":null,"abstract":"<p><strong>Purpose: </strong>We describe very young adolescent (VYA, 10-14) and adolescent (15-19) births in Mexico before and after the implementation of the National Strategy for the Prevention of Adolescent Pregnancy (ENAPEA in Spanish) in 2015, which has as the goal to halve adolescents' overall fertility and eradicate births in those under 15.</p><p><strong>Methods: </strong>We used administrative birth certificate data, 2008-2019 and calculated the proportions of births and birthrates by age group over time. We then calculated the change in proportion of births and in birthrates before (2008-2014) and after (2015-2019) ENAPEA at national and state level. We used linear regression models to assess association between changes in birthrates and the implementation of ENAPEA. We also calculated the proportion of births that were first versus second- or higher-order births.</p><p><strong>Results: </strong>Overall, about 20% of births in Mexico are to VYA and adolescents, with little change over time. VYA and adolescent births increased or were stable in the pre-ENAPEA (2008-2014) period and declined in the post-ENAPEA period (2015-2019). Small but significant reductions in birthrates for both age groups are associated with the beginning of the implementation of ENAPEA. There were important reductions in the proportion of births that are second order or higher.</p><p><strong>Discussion: </strong>Our results provide some key insights to help understand declines in adolescent births in the context of ENAPEA, with a particular focus on VYA mothers and a novel insight on first and second-/third-order births.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life's Essential 8 and Depression: A National Cross-Sectional Analysis in US Emerging Adults.","authors":"Yanwei You, Kefeng Zheng, Alimjan Ablitip, Dizhi Wang, Chaofan Chen, Yajing Liu, Yuquan Chen, Xindong Ma","doi":"10.1016/j.jadohealth.2025.03.023","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.023","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the association between adherence to Life's Essential 8 (LE8) and depression in a nationally representative sample of US emerging adults, including both overall and subgroup analyses by gender, age, and other sociodemographic factors.</p><p><strong>Methods: </strong>Data from 2,219 emerging adults from the National Health and Nutrition Examination Survey (2007-2018) were analyzed. Depression was measured using the Patient Health Questionnaire-9, with scores ≥10 indicating depression. LE8 scores were calculated based on cardiovascular health factors, and covariates included demographic and behavioral variables. Weighted logistic regression was used to assess associations between LE8 and depression.</p><p><strong>Results: </strong>Participants with higher LE8 scores had lower odds of depression. In the fully adjusted model, which adjusted for sociodemographic variables, the odds of depression were significantly lower in the highest quartile of LE8 adherence (odds ratio (OR) = 0.252, 95% confidence interval (CI): 0.233-0.289, p < .001) compared to the lowest quartile. Continuous LE8 scores were also inversely associated with depression (OR = 0.961, 95% CI: 0.949-0.974, p < .001). Gender-stratified analyses showed that the protective effect of higher LE8 scores was more pronounced in males (OR = 0.956, 95% CI: 0.934-0.979, p < .001) than in females (OR = 0.960, 95% CI: 0.945-0.975, p < .001).</p><p><strong>Discussion: </strong>Better cardiovascular health, as indicated by higher LE8 scores, was strongly linked to lower depression in emerging adults. Targeted interventions promoting key behaviors like sleep and physical activity could effectively reduce depression in this population.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Race and Ethnicity Moderates the Relationship Between Family Income Level and Allostatic Load Among Adolescents in the United States.","authors":"Karen Jennings Mathis, Laura R Stroud, Samantha R Rosenthal, Hannah N Ziobrowski","doi":"10.1016/j.jadohealth.2025.03.015","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.015","url":null,"abstract":"<p><strong>Purpose: </strong>People from low-income households are at risk of high allostatic load (AL) in adulthood, which is linked to poor physical and mental health outcomes. It is unclear how early the income-AL link develops and whether this association differs by race and/or ethnicity. We examined associations of family income with high AL among adolescents and whether race and/or ethnicity modified associations.</p><p><strong>Methods: </strong>Cross-sectional, nationally representative data came from 748 US adolescents (aged 12-17 years) who participated in the prepandemic 2017-March 2020 National Health and Nutrition Examination Survey. Family income was measured using poverty-income ratio (PIR) and categorized as low income (PIR <1.0), middle income (PIR 1.0-4.0), and high income (PIR >4.0). AL was derived from 9 biomarkers. Modified Poisson regression models estimated prevalence ratios (PRs) for associations of family income with high AL overall and stratified by race and/or ethnicity (non-Hispanic White, non-Hispanic Black, and Hispanic).</p><p><strong>Results: </strong>Nearly 1 in 5 adolescents (19.7%) met the criteria for high AL. Compared to high-income peers, middle-income adolescents had more than twice the prevalence of high AL (PR: 2.16; 95% confidence interval: 1.13-4.13), and low-income adolescents had nearly triple the prevalence of high AL (PR: 2.98; 95% confidence interval: 1.76-5.04). Stratified models observed these associations only for non-Hispanic White adolescents, while for non-Hispanic Black and Hispanic youth, associations were attenuated and nonsignificant.</p><p><strong>Discussion: </strong>Higher family income was protective against high AL only for non-Hispanic White adolescents. Minority youth may face additional stressors that diminish the protective effects of higher income.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health and Wellbeing Outcomes Among Trans Young People in Australia Who are Supported to Affirm Their Gender.","authors":"Natalie Amos, Ruby Grant, Ashleigh Lin, Adam O Hill, Ken C Pang, S Rachel Skinner, Teddy Cook, Marina Carman, Adam Bourne","doi":"10.1016/j.jadohealth.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.011","url":null,"abstract":"<p><strong>Purpose: </strong>Young trans people face elevated rates of poor mental health and well-being outcomes. Affirming their gender in ways that are meaningful to them has important implications for these outcomes. However, limited research has examined the role of feeling supported to affirm their gender.</p><p><strong>Methods: </strong>This study used the data of 1,697 trans youth drawn from a large survey of LGBTQA+ 14-21-year-olds in Australia. Regression analyses examined how feeling supported to affirm gender medically, legally, or socially, among those who expressed a desire to do so, was associated with mental health and well-being outcomes.</p><p><strong>Results: </strong>Participants who felt supported to affirm their gender medically, legally, or socially, reported less suicidal ideation and self-harm in the past 12 months as well as lower psychological distress, lower anxiety, and greater happiness. Support for medical and legal affirmation was associated with less suicide attempt in the past 12 months. Support for each form of gender affirmation was associated with lower odds of experiencing bias-based verbal and sexual harassment in the past 12 months, with support for legal and social affirmation associated with lower odds of experiencing bias-based physical harassment. Support for each form of gender affirmation was associated with lower odds of experiencing homelessness.</p><p><strong>Discussion: </strong>Supporting trans youth to affirm their gender in the ways that are meaningful to them is key to their health and well-being. Those who are in a position to provide support to young trans people to affirm their gender must be encouraged and equipped to do so.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-Specific Predictors of E-Cigarette and Cigarette Use Trajectory Classes From Preadolescence to Late Adolescence (2013-2020) of the Population Assessment of Tobacco and Health (PATH) Study.","authors":"Cassandra A Stanton, Zhiqun Tang, Eva Sharma, Anikah H Salim, MeLisa R Creamer, Andrea L Ruybal, Daniela Marshall, Ibrahim Zaganjor, Marushka L Silveira, Derick L Rivers, Babita Das, Charles Deljohn Carr, Janine C Delahanty, Jia Wang, Heather L Kimmel, Wilson M Compton, Andrew J Hyland, Jennifer L Pearson","doi":"10.1016/j.jadohealth.2025.03.010","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.010","url":null,"abstract":"<p><strong>Purpose: </strong>In the US, youth e-cigarette use is more prevalent than cigarette use. Among younger adolescents in US middle schools, use of any nicotine/tobacco product is on the rise. Different factors may drive transitions from susceptibility to initiation, and less is known about early adolescent transitions.</p><p><strong>Methods: </strong>Data were drawn from US early adolescents (aged 12-13 years) at Wave (W) 1 of the Population Assessment of Tobacco and Health (PATH) Study across 7 waves (2013-2020) into older adolescents (aged 18-19 years). Unweighted longitudinal latent class analyses identified trajectory classes of e-cigarette and cigarette susceptibility and use in separate models. Weighted multinomial logistic regression analyses examined time-specific predictors of divergent trajectories.</p><p><strong>Results: </strong>Five e-cigarette classes (weighted 45.1% Never Use, 15.4% Susceptible, 6.9% Initiated only, 19.9% W5 Progressed/discontinued, and 12.7% Progressed/persisted) and 4 cigarette classes (weighted 61.2% Never Use, 21.3% Susceptible, 10.6% W4.5 Progressed/discontinued, and 6.9% Former Use) were identified. In 2020 (the first year of the COVID-19 pandemic), discontinued use of both products was observed. Only the e-cigarette model identified a class with persistent use through 2020. Daily social media use and advertising exposure were specifically important to susceptibility and initiation of e-cigarettes among younger adolescents. Best friend use, low perceptions of product harm, and substance use problems showed strong associations with trajectories of e-cigarettes and cigarettes.</p><p><strong>Discussion: </strong>Trajectories for both products revealed a period of susceptibility before use that may be particularly amenable to early intervention. It is important to monitor daily social media use and advertising exposure to prevent e-cigarette susceptibility and initiation.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Policy and Health for Sexual and Gender Minority Youth in the United States: A Scoping Review.","authors":"Jessica N Fish, Lauryn Dunkwu, Nedelina Tchangalova, Sydney McFarlane","doi":"10.1016/j.jadohealth.2025.02.018","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.02.018","url":null,"abstract":"<p><p>Strengthening policy research and its translation is essential to improving sexual and gender minority youth (SGMY) health. We conducted a scoping review of studies testing the relationship between policy and health for SGMY (aged 13-26) living in the United States to document the scope of research in this area and identify opportunities to advance research in SGMY health policy. Guided by the Population, Concept, and Context framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews checklist, we searched seven databases for English peer-reviewed studies published between 2000 and 2023 that tested the association between individual or composite measures of policy and mental health, substance use, or sexual health for SGMY aged 26 or younger. Twenty-one studies met the inclusion criteria. Most were cross-sectional and heavily relied on Youth Risk Behavior Survey data. Eighteen studies observed significant associations between policy and health for SGMY; only two assessed this association specifically for transgender youth. SGMY health and policy scholarship would advance through improved sexual orientation and (in particular) gender identity data collection in national data sources, measurement guidance and design testing, a greater use of longitudinal and quasiexperimental methods, and assessment of proximal mechanisms and implementation strategies through which policies impact health.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Childhood Experiences are Associated With e-Cigarette Abstinence in a Vaping Cessation Randomized Clinical Trial Among Adolescents.","authors":"Amanda L Graham, Sarah Cha, Megan A Jacobs, Giselle Edwards, Anna L Funsten, George D Papandonatos","doi":"10.1016/j.jadohealth.2025.04.012","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.04.012","url":null,"abstract":"<p><strong>Purpose: </strong>Adverse childhood experiences (ACEs) are linked to e-cigarette use. To date, no studies have examined the association between ACEs and e-cigarette cessation. This study examined the relationship between ACEs and vaping cessation outcomes among adolescent e-cigarette users.</p><p><strong>Methods: </strong>Participants were n = 1,248 adolescent (13-17 years) e-cigarette users recruited nationally to a randomized clinical trial of vaping cessation who completed the PEdiatric ACEs and Related Life Events Screener at baseline. The primary outcome was 30-day point prevalence abstinence from nicotine vaping at 7 months (missingness = vaping). Analyses examined associations between vaping cessation and individual ACEs items, risk strata (low: 0 ACEs; intermediate: 1-3 ACEs; high: ≥4 ACEs), and domains of adversity using inverse probability of retention weighted logistic regression adjusted for baseline confounders.</p><p><strong>Results: </strong>Most participants (90.1%) reported at least 1 ACE, with 55.8% classified as high risk (≥4 ACEs). High-risk participants showed 20% lower abstinence rates compared to combined low or intermediate-risk groups (risk ratio = 0.79, 95% confidence interval = 0.69-0.91, p < .001). Each additional abuse experience was associated with a 7% decrease in abstinence rates (risk ratio= 0.93, 95% confidence interval = 0.87-0.99, p = .028), while neglect and household dysfunction domains showed no significant associations with cessation outcomes.</p><p><strong>Discussion: </strong>This study provides the first evidence of an inverse relationship between ACEs and vaping cessation success among adolescents. The results suggest that trauma-informed approaches may be valuable additions to youth vaping cessation interventions.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual and Reproductive Health in Sickle Cell Disease: A Qualitative Analysis of Pediatric Hematologist Perspectives.","authors":"Anjali Rajkumari Oberoi, Alison R Clarke, Seethal A Jacob, Traci M Kazmerski, Hannah Fassel, Megan Askew, Teonna Woolford, Karol Walec, Maayan Leroy-Melamed","doi":"10.1016/j.jadohealth.2025.03.008","DOIUrl":"https://doi.org/10.1016/j.jadohealth.2025.03.008","url":null,"abstract":"<p><strong>Purpose: </strong>Significant progress in managing sickle cell disease (SCD) has led to improved mortality and a growing population of people living with SCD. Sexual and reproductive health (SRH) for individuals with SCD is a critical but under-addressed aspect of care. This study characterizes clinicians' current practices in SRH care for adolescents with SCD.</p><p><strong>Methods: </strong>In a cross-sectional qualitative study, we recruited clinicians who care for adolescents with SCD from a national professional listserv. Participants completed in-depth semistructured qualitative interviews over video conference from May 2022 to May 2023. The study involved 20 SCD providers (14 female and 6 male). Interviews explored the clinician's role, perceived barriers and facilitators, and recommendations for SRH care for adolescents with SCD.</p><p><strong>Results: </strong>Key concerns identified included managing vaso-occlusive events during menstruation, priapism, and contraceptive choice. Clinicians expressed different readiness for incorporating SRH care in their practice and identified barriers, such as training, time, and subspecialist availability. While all participants acknowledged the priority of SRH care for adolescents with SCD, clearly outlined guidelines are needed to enhance counseling and the provision of SRH care. Clinicians with specific expertise or familiarity with the patient are best suited to providing aspects of SRH care.</p><p><strong>Discussion: </strong>This study emphasizes clinician interest in comprehensive SRH care for individuals with SCD. Well-defined guidelines are necessary to aid clinicians in addressing the unique SRH needs in SCD. Further study is needed to understand patient attitudes and establish evidence-based guidelines for SRH in SCD.</p>","PeriodicalId":520803,"journal":{"name":"The Journal of adolescent health : official publication of the Society for Adolescent Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}