Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association最新文献

{"title":"Empowering trainee fellows today will ensure that we build tomorrow's leaders in gastroenterology.","authors":"Zaki Alhashimalsayed","doi":"10.4103/sjg.sjg_312_25","DOIUrl":"10.4103/sjg.sjg_312_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"313-314"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the unique concerns of Arab patients with inflammatory bowel disease: A cross-sectional study and the case for region-specific support groups.","authors":"Nadeen M Omar, Mohamed N Alzaabi, Maryam A Alahmad, Mohammed N Quraishi","doi":"10.4103/sjg.sjg_182_25","DOIUrl":"10.4103/sjg.sjg_182_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"284-291"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic and clinical implications of metabolic dysfunction-associated steatotic liver disease management: Regional challenges and opportunities in Middle East and North Africa.","authors":"Mohamed El-Kassas, Faisal M Sanai","doi":"10.4103/sjg.sjg_247_25","DOIUrl":"10.4103/sjg.sjg_247_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"249-251"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-national comparison of inflammatory bowel disease burden in China, Japan, the United States, and India: An age-period-cohort analysis of GBD 2021.","authors":"Zhimei Sun, Biao Yin, Tianen Hou, Taofeng Jiang","doi":"10.4103/sjg.sjg_124_25","DOIUrl":"10.4103/sjg.sjg_124_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"274-283"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A chain is only as strong as its weakest link: Care pathways in colorectal cancer, from emergency interventions to preventive strategies.","authors":"Majid A Almadi, Muhammad F Mubarak","doi":"10.4103/sjg.sjg_234_25","DOIUrl":"10.4103/sjg.sjg_234_25","url":null,"abstract":"","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"193-196"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144629418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between gastroesophageal reflux and chronic kidney disease: A meta-analysis of 4 million patients.","authors":"Andres Chaponan-Lavalle, Ambar Godoy, Jose M Estrada-Grossmann, Eduardo S Acosta, Yolanda Chaponan-Lavalle, Luis G Azañedo-Garcia, Karina Ordaya-Gonzales, Manuel Gonzales-Palomo, Fortunato S Príncipe-Meneses, Arjunmohan Mohan, Renato Beas, Jose Arriola-Montenegro","doi":"10.4103/sjg.sjg_133_25","DOIUrl":"10.4103/sjg.sjg_133_25","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) has been associated with higher risk of gastrointestinal disorders, particularly Gastroesophageal reflux disease (GERD). However, the magnitude of this association and the underlying mechanisms remains unclear.</p><p><strong>Methods: </strong>A systematic search was conducted across major databases from inception to November 2024. We included cross-sectional and case-control studies evaluating the relationship between CKD and GERD. Data were extracted and analyzed using a random-effects model to calculate pooled odds ratios (ORs) and prevalence rates. Study quality was assessed using the Newcastle-Ottawa Scale, and heterogeneity was evaluated using the Cochran's Q test and I² statistic.</p><p><strong>Results: </strong>Nine studies involving 4,650,709 participants were included. The pooled prevalence of GERD among CKD patients was 18% (95% CI: 0.10-0.26, I² =93.64%). The pooled crude OR for the association between CKD and GERD was 2.53 (95% CI: 1.30-4.92) and adjusted OR was 1.48 (95% CI: 1.05-2.08).</p><p><strong>Conclusion: </strong>This meta-analysis reveals a marginally significant association between CKD and GERD, highlighting higher prevalence of GERD among individuals with CKD. Furthers studies are needed to elucidate the underlying pathophysiological mechanisms and potential clinical implications.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"206-211"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The index endoscopic characteristics associated with gastric neoplasms in serial screening of upper gastrointestinal endoscopy.","authors":"Jung Huh, Su Hwan Kim, Kwang Woo Kim, Yun Jin Jeong, Dong Jun Oh, Dong Kee Jang, Heejoon Jang, Ji Bong Jeong, Ji Won Kim, Kook Lae Lee, Hyoun Woo Kang","doi":"10.4103/sjg.sjg_31_25","DOIUrl":"10.4103/sjg.sjg_31_25","url":null,"abstract":"<p><strong>Background: </strong>Although biennial upper gastrointestinal endoscopy is recommended for gastric cancer screening in Korea, data regarding the endoscopic characteristics associated with the diagnosis of gastric neoplasms in serial endoscopic screening are limited. We aimed to evaluate the index endoscopic characteristics associated with the diagnosis of gastric neoplasms and adequate gastric cancer screening interval.</p><p><strong>Methods: </strong>We retrospectively reviewed cases of the patients diagnosed with gastric neoplasms, who showed no evidence of gastric neoplasms on index endoscopy between October 2005 and December 2022. The indices of endoscopic characteristics were analyzed. Patients were stratified according to the interval between endoscopic examinations (≤1, 1-2, 2-3, and >3 years), and the proportion of adenoma, early gastric cancer (EGC) and advanced gastric cancer (AGC) was analyzed across groups.</p><p><strong>Results: </strong>A total of 331 lesions with histological diagnoses of gastric neoplasms (167 adenomas, 138 EGCs, and 26 AGCs) were included. The initial baseline endoscopic findings were as follows: normal, 22 (6.7%); gastritis, 16 (4.8%); erosion, 65 (19.6%); ulcers, 19 (5.8%); atrophy, 104 (31.4%); and intestinal metaplasia, 105 (31.7%). The proportion of AGC increased with longer surveillance intervals: 0% at ≤1 year (median: 0.76 years, interquartile range [IQR]: 0.38), 3.1% at 1-2 years (1.59; 0.57), 6.7% at 2-3 years (2.37; 0.51), and 20.0% at >3 years (4.18; 1.53). Conversely, adenoma were most frequently detected within 1 year, comprising 63.6% ( P < 0.05).</p><p><strong>Conclusion: </strong>Cautious follow-up endoscopy may be necessary for patients demonstrating endoscopic findings of atrophy and intestinal metaplasia. Shorter surveillance intervals enable early detection of gastric neoplasia and may prevent progression to advanced cancer.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"219-226"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical outcomes of curative intent management in emergency vs. elective colon cancer: A retrospective single center study.","authors":"Noura S Alhassan, Thamer A Bin Traiki, Sulaiman A Alshammari, Mohaned Makkawi, Yazeed A Alkhayyal, Mohammed A Alswayyed, Maha-Hamadien Abdulla, Ahmad M Zubaidi, Omar A Al-Obeed, Reem A Alharbi, Khayal A AlKhayal","doi":"10.4103/sjg.sjg_101_25","DOIUrl":"10.4103/sjg.sjg_101_25","url":null,"abstract":"<p><strong>Background: </strong>Presentation affects several surgical parameters and post-operative outcomes. This study compares emergency versus elective colon cancer outcomes and prognostic factors associated with postoperative complications.</p><p><strong>Methods: </strong>All colon cancer patients who underwent curative resection between July 2015 and December 2019 were retrospectively reviewed and analyzed. Patients were divided into emergency and elective groups based on their presentation.</p><p><strong>Results: </strong>A total of 215 patients were included; 70 patients (32.6%) in the emergency group. Of them, 61 patients presented with obstruction, and nine with free perforation. The elective group had a higher laparoscopic approach (82.8%) with primary anastomosis (90.3%) compared to the emergency group (57.1% and 68.6%, respectively, P < 0.001). Postoperative complications were clinically higher in the emergency group (30% vs. 20.7%, P = 0.171). ICU/HDU admission was higher in the emergency group (40% vs. 17.2%, P < 0.001), and had a longer hospital stay (15 vs. 10 days, P < 0.003). Regression analysis revealed increased risk of complications among patients with comorbidities (OR 3.21; 95% CI, P = 0.002), albumin levels <30g/dl (OR 2.20; 95% CI, P = 0.01), complete obstruction (OR 2.42; 95% CI, P = 0.017), perforation (OR 9.98; 95% CI, P < 0.001), and open surgery (OR 4.84; 95% CI, P < 0.001).</p><p><strong>Conclusion: </strong>Emergency presentation rate was high among our patients with less-favorable surgical outcomes. Open surgery and stoma creation were more prevalent in the emergency group. Complete obstruction, perforation, open surgery, hypo-albuminemia, and presence of comorbidities were independent risk factors for complications.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"233-240"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empowering GI fellows to lead the change: A national survey on strengths and opportunities to enhance gastroenterology training in Saudi Arabia.","authors":"Syed A Gardezi, Jafar M Albagshi, Aymen Almuhaidb, Bader Alajlan, Mohammed Al Jawad","doi":"10.4103/sjg.sjg_122_25","DOIUrl":"10.4103/sjg.sjg_122_25","url":null,"abstract":"<p><strong>Background: </strong>The increasing burden of gastrointestinal and liver diseases in Saudi Arabia highlights the need for a strong, standardized GI training program to produce highly skilled gastroenterologists. Historically, joint rotational training programs offered broad exposure but inconsistent mentorship and evaluation. Recently, center-based independent fellowships were introduced to address these challenges, although disparities between high- and low-volume centers persist.</p><p><strong>Methods: </strong>A national survey was conducted using Google Surveys from February to December 2024, targeting GI fellows across Saudi Arabia. The survey was developed based on literature review and validated through pilot testing among fellows during a regional board review course. Participation was encouraged through local representatives and gastroenterology meetings. Data were analyzed using descriptive statistics and thematic analysis.</p><p><strong>Results: </strong>Fifty-four fellows responded. The average satisfaction score was 3.96 of 5, with third-year fellows reporting the highest satisfaction. Strengths included strong endoscopic exposure and collaborative rotations. Mentorship scored lower at 2.78. Only about half of respondents reported opportunities for research, leadership training, or access to hands-on courses. Dedicated teaching sessions were available to just 40.7% of fellows, reflecting significant variability across centers.</p><p><strong>Conclusions: </strong>While GI training in Saudi Arabia has improved, notable disparities remain. Standardizing curricula, strengthening mentorship, expanding simulation-based training, and improving research and leadership opportunities are critical steps. Integrating successful international models could accelerate progress, ensuring that Saudi Arabia produces confident, competent gastroenterologists ready to meet both national and global healthcare demands.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"241-247"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and outcome of biliary atresia in the United Arab Emirates: A multicenter national study.","authors":"Manal Salem Alkatheeri, Haifa Alawadhi, Mira Almheiri, Saista Amin, Abid Qazi, Christos Tzivinikos, Doha Muneer, Rana Bitar","doi":"10.4103/sjg.sjg_38_25","DOIUrl":"10.4103/sjg.sjg_38_25","url":null,"abstract":"<p><strong>Background: </strong>While extensive research provides valuable insights into biliary atresia (BA) globally, there remain gaps in region-specific data, such as West Asia. We aim to evaluate the incidence and survival of patients with BA in the United Arab Emirates.</p><p><strong>Methods: </strong>We retrospectively reviewed the records of all patients diagnosed with BA in all paediatric tertiary hospitals from 2011 to 2021.</p><p><strong>Results: </strong>50 patients were identified, 11 were excluded due to insufficient information to confirm a diagnosis of BA. The final cohort was 39 patients. The overall incidence of biliary atresia was 3.75 per 100,000 live births. The incidence rates varied over the years, with the lowest recorded incidence in 2011 at 1.19 per 100,000 live births and the highest in 2017 at 7.16 per 100,000 live births. The median age at Kasai portoenterostomy procedure was 52 days (CI: 42-60, range: 6-142) The survival with native liver was 50% at 12 months, and 42.1% at 5 and 10 years post-operatively. The overall survival with native or transplant liver was 88.2% at 5 and 10 years.</p><p><strong>Conclusion: </strong>While the incidence of BA is variable worldwide, the incidence in the United Arab Emirates in amongst the lowest reported. The role of early diagnosis and specialized surgical intervention is of importance for patient survival with native liver. The overall patient survival is further enhanced by availability of well-structured liver transplantation programs.</p>","PeriodicalId":520774,"journal":{"name":"Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association","volume":" ","pages":"227-232"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144629419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}