Egyptian Journal of Pediatric Allergy and Immunology最新文献_第4页

Abstracts from International Publications 国际出版物摘要

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2021-04-01 DOI: 10.21608/EJPA.2021.164799

N. Heshmat

引用次数: 0

The Potential Effect of Dietary Modifications on the Management of Food Allergies 饮食调整对食物过敏管理的潜在影响

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2021-04-01 DOI: 10.21608/EJPA.2021.60350.1022

Caner Ozyildirim, N. Ayhan

引用次数: 0

Patterns of sensitization to food allergens among allergic adults and children following-up in Zagazig university hospitals, Egypt 在埃及扎加齐格大学医院随访的过敏成人和儿童对食物过敏原的致敏模式

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2021-04-01 DOI: 10.21608/EJPA.2021.44948.1013

R. E. El Shabrawy, Nehal El Shabrawy, Dina S. El-rafey

{"title":"Patterns of sensitization to food allergens among allergic adults and children following-up in Zagazig university hospitals, Egypt","authors":"R. E. El Shabrawy, Nehal El Shabrawy, Dina S. El-rafey","doi":"10.21608/EJPA.2021.44948.1013","DOIUrl":"https://doi.org/10.21608/EJPA.2021.44948.1013","url":null,"abstract":"INTRODUCTION It was thought that food allergy (FA) in the developing world was rare, but emerging epidemiological data have shown otherwise in the recent decade. This could be attributed to the previous under-recognition or underreporting of FA prevalence. Indeed, the health burden of food allergy is anticipated to rise substantially in the next decade. Food allergy present in different forms, including urticaria, angioedema, exacerbation of allergic rhinitis, asthma, or atopic dermatitis. Food allergic patients with asthma have a higher risk of developing life-threatening food-induced reactions and an asthmatic patient with a food allergy can have higher rates of morbidity and mortality associated with asthma. The most serious consequence of food allergy is anaphylaxis. Food allergy has significant deleterious effects on family economics, social interactions, school and work attendance, and health-related quality of life. Children with multiple food allergies face many nutritional problems as a consequence of an unsupervised elimination diet, which may lead to failure to thrive. There is a lack of reliable data regarding FA in most developing countries, including Egypt. 1,6 This study aimed to uncover some aspects of IgE mediated FA among the Egyptian population. We sought to explore the frequency of food sensitization among a sample of allergic patients and determine the common sensitizing food allergens among those patients.","PeriodicalId":52068,"journal":{"name":"Egyptian Journal of Pediatric Allergy and Immunology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77246746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wheat allergy 小麦过敏

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-10-03 DOI: 10.1016/b978-0-12-821715-3.00009-5

Z. El-Sayed, G. Shousha

引用次数: 76

The Pediatric Allergy and Immunology Unit of Ain Shams University in times of SARS-CoV-2 pandemic: approach and challenges 在严重急性呼吸系统综合征冠状病毒2型大流行期间，艾因沙姆斯大学儿科过敏和免疫学部门：方法和挑战

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-10-03 DOI: 10.21608/ejpa.2020.117833

Y. El-Gamal, Z. El-Sayed, E. Hossny, S. Reda, D. El-Ghoneimy, Rasha H. El-Owaidy, N. Radwan, G. Shousha, A. Elmekkawy, Amal Lotfy, Mariam Abdelnaby, Roba Al-Gaweesh, Rana Zakaria, Mostafa El-Amin

引用次数: 0

2019 ARIA Care pathways for allergic rhinitis – Egypt 2019 ARIA过敏性鼻炎护理途径-埃及

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-04-01 DOI: 10.21608/ejpa.2020.81763

Y. El-Gamal, Rasha H. El-Owaidy, S. El-Sayed, Z. El-Sayed, E. Hossny, S. Reda, C. Bachert, W. Fokkens, T. Haahtela, P. Hellings, L. Klimek, N. Papadopoulos, N. Pham‐Thi, O. Pfaar, A. Valiulis, M. Ventura, G. Onorato, W. Czarlewski, A. Bedbrook, J. Bousquet

引用次数: 0

Editorial 编辑

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Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-04-01 DOI: 10.21608/ejpa.2020.80619

Y. El-Gamal

引用次数: 0

IF 0.3

Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-04-01 DOI: 10.21608/ejpa.2020.81766

E. Hossny, Rasha H. El-Owaidy, B. A. Raouf, Samia Aboajela A. Innajih

{"title":"Health-related quality of life assessment using EQ-5D-Y questionnaire in a group of Egyptian asthmatic children","authors":"E. Hossny, Rasha H. El-Owaidy, B. A. Raouf, Samia Aboajela A. Innajih","doi":"10.21608/ejpa.2020.81766","DOIUrl":"https://doi.org/10.21608/ejpa.2020.81766","url":null,"abstract":"hildren's quality of life. We sought to investigate the health-related quality of life (HRQoL) in a sample of Egyptian asthmatic children. Methods: A cross-sectional study was conducted in the Pediatric Allergy and Immunology Unit of Ain Shams University, including three groups of age and gender-matched children, aged 6-12 years; an asthma group (n=100), non-asthmatic group with respiratory tract infections (n=114), and a healthy control group (n=100). The EQ-5D-Y questionnaire was used to evaluate the HRQoL in each study group. This questionnaire also comprises a visual analogue scale (VAS) which is scored from zero (worst) to 100 (best) as judged by the patient. Results: HRQoL assessment revealed that 86% of the asthmatic children faced problems with their daily activities, 43 % had worries, sadness and unhappiness and 22% had mobility problems (walking around). Thirteen percent of the cases expressed some pain or discomfort due to their disease, while self-care was the least affected (6%). Parameters of mobility, doing usual activities, feeling worried or sad were more frequently affected among the asthmatics in comparison to the other two groups (X2 = 37.02, 46.38, 22.90, respectively with p <0.001). Enrolled asthmatic children showed the lowest values of visual analogue scale (VAS) scores (mean ± SD: 72.2 ± 24.6) in comparison to the infection and healthy control groups (mean ± SD: 84.6 ± 12, 92.8 ± 9.6, respectively; f = 39.03; p value = 0.001). Conclusion: Asthma has a significant adverse impact on HRQoL of children and the EQ-5D-Y questionnaire could be an applicable instrument to measure their quality of life.","PeriodicalId":52068,"journal":{"name":"Egyptian Journal of Pediatric Allergy and Immunology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84084280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Interferon gamma: is it a co-player in the pathogenesis of idiopathic nephrotic syndrome? 干扰素γ:它是特发性肾病综合征发病机制的共同参与者吗?

IF 0.3

Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-04-01 DOI: 10.21608/ejpa.2020.81768

A. Hassan, Ihab Z. El-Hakim, N. Amr, D. El-Ghoneimy, D. Soliman, D. Sallam

{"title":"Interferon gamma: is it a co-player in the pathogenesis of idiopathic nephrotic syndrome?","authors":"A. Hassan, Ihab Z. El-Hakim, N. Amr, D. El-Ghoneimy, D. Soliman, D. Sallam","doi":"10.21608/ejpa.2020.81768","DOIUrl":"https://doi.org/10.21608/ejpa.2020.81768","url":null,"abstract":"Introduction: Idiopathic nephrotic syndrome (INS), the most common form of NS in childhood, was considered 4 decades ago as a systemic disorder of T cells, mediated through its released cytokines. To date, the exact incriminated cytokine or immunological mediator is not properly defined. Interferon-gamma (IFN-gamma), a pro-inflammatory cytokine, is thought to have a role in the provocation of the T cell-mediated INS relapse, through the promotion of T helper1 (Th1) differentiation and suppression of regulatory T cells (Treg). Aim of the study: To evaluate the immunopathogenic role of IFN-gamma in children with steroid-sensitive idiopathic nephrotic syndrome (SSNS) through monitoring the changes in its levels with disease course. Methods: This study included twenty-five newly diagnosed children with SSINS. They were all given full dose prednisolone, evaluated at initial diagnosis and at full remission as regards the serum level of IFN-gamma. Results: Serum levels of IFN-gamma were lowermost at the time of diagnosis and increased with remission on corticosteroids. Conclusions: This study points to a role for the lower serum IFN-gamma at diagnosis, in the immunopathogenesis of INS than at remission and the rise in its serum level might be a marker of remission induction, however, this awaits confirmation in larger-scale studies. Studies on renal biopsy specimens are needed to determine the exact renal in situ levels and effects of IFN-gamma","PeriodicalId":52068,"journal":{"name":"Egyptian Journal of Pediatric Allergy and Immunology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44087410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated serum KL-6 in pediatric asthma exacerbation: a proof of alveolar injury 儿童哮喘加重时血清KL-6升高:肺泡损伤的证据

IF 0.3

Egyptian Journal of Pediatric Allergy and Immunology Pub Date : 2020-04-01 DOI: 10.21608/ejpa.2020.81767

I. Draz, Iman A Shaheen, E. Youssef

{"title":"Elevated serum KL-6 in pediatric asthma exacerbation: a proof of alveolar injury","authors":"I. Draz, Iman A Shaheen, E. Youssef","doi":"10.21608/ejpa.2020.81767","DOIUrl":"https://doi.org/10.21608/ejpa.2020.81767","url":null,"abstract":"Background: Asthma is one of the most popular chronic diseases in children. It is defined as a complicated inflammatory disorder in which the patient suffers from chronic and persistent inflammation of the airways. The sialylated glycoprotein Krebs von den Lungen-6 (KL-6), one of the lung epithelium-specific proteins, has been recognized as a significant biomarker which directly associates with interstitial lung disease (ILD) pathogenesis, indicating the extent of damage and regeneration of type II pneumocytes. Objective: the aim of this study is to investigate the degree of alveolar damage in asthmatic children with acute exacerbation as reflected by serum KL-6 levels. Methods: This cross-sectional controlled study included 50 patients with acute asthma exacerbation diagnosed as per the GINA guidelines definition and 50 age- and sex-matched healthy children as controls. Spirometry was done for all participants. Serum KL-6 level was estimated by Enzyme Linked Immunosorbent Assay (ELISA), and total serum IgE level was measured via the electrochemiluminescence technology. Results: The asthma patients included 35 (70%) males and 15 (30%) females with mean age of 10.76 ±1.9 years. Forty-seven patients (94%) had a positive family history of bronchial asthma and 32 (64%) had other atopic manifestations The mean serum KL-6 level in patients was more than double the mean level of the control group (115.79 vs 55.64). No significant relation was observed between KL-6 serum level and age, family history of asthma, seasonal variation, or atopic manifestation among the cases. Serum total IgE levels were significantly higher in cases compared to controls (P<0.05). Conclusion: Serum KL-6 levels in pediatric asthma patients may be a useful diagnostic tool for detecting and monitoring the severity of airway inflammation. The use of serum KL-6 alone may help to differentiate between asthmatic patients in exacerbation and healthy controls.","PeriodicalId":52068,"journal":{"name":"Egyptian Journal of Pediatric Allergy and Immunology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90359559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1