在埃及扎加齐格大学医院随访的过敏成人和儿童对食物过敏原的致敏模式

Pub Date : 2021-04-01 DOI:10.21608/EJPA.2021.44948.1013
R. E. El Shabrawy, Nehal El Shabrawy, Dina S. El-rafey
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引用次数: 0

摘要

人们认为食物过敏(FA)在发展中国家是罕见的,但最近十年新出现的流行病学数据却显示出相反的情况。这可能归因于以前对FA患病率的认识不足或报告不足。事实上,食物过敏的健康负担预计将在未来十年大幅上升。食物过敏表现为不同形式,包括荨麻疹、血管性水肿、变应性鼻炎加重、哮喘或特应性皮炎。患有哮喘的食物过敏患者发生危及生命的食物引起的反应的风险更高,患有食物过敏的哮喘患者与哮喘相关的发病率和死亡率更高。食物过敏最严重的后果是过敏反应。食物过敏对家庭经济、社会交往、上学和工作出勤率以及与健康相关的生活质量都有显著的有害影响。患有多种食物过敏的儿童由于没有监督的消除饮食而面临许多营养问题,这可能导致无法茁壮成长。在大多数发展中国家,包括埃及,缺乏关于FA的可靠数据。本研究旨在揭示埃及人群中IgE介导的FA的某些方面。我们试图探索过敏患者样本中食物致敏的频率,并确定这些患者中常见的致敏食物过敏原。
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Patterns of sensitization to food allergens among allergic adults and children following-up in Zagazig university hospitals, Egypt
INTRODUCTION It was thought that food allergy (FA) in the developing world was rare, but emerging epidemiological data have shown otherwise in the recent decade. This could be attributed to the previous under-recognition or underreporting of FA prevalence. Indeed, the health burden of food allergy is anticipated to rise substantially in the next decade. Food allergy present in different forms, including urticaria, angioedema, exacerbation of allergic rhinitis, asthma, or atopic dermatitis. Food allergic patients with asthma have a higher risk of developing life-threatening food-induced reactions and an asthmatic patient with a food allergy can have higher rates of morbidity and mortality associated with asthma. The most serious consequence of food allergy is anaphylaxis. Food allergy has significant deleterious effects on family economics, social interactions, school and work attendance, and health-related quality of life. Children with multiple food allergies face many nutritional problems as a consequence of an unsupervised elimination diet, which may lead to failure to thrive. There is a lack of reliable data regarding FA in most developing countries, including Egypt. 1,6 This study aimed to uncover some aspects of IgE mediated FA among the Egyptian population. We sought to explore the frequency of food sensitization among a sample of allergic patients and determine the common sensitizing food allergens among those patients.
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