Journal of preventive medicine and public health = Yebang Uihakhoe chi最新文献

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[Smoking and colorectal cancer risk in the Korean elderly]. [吸烟与韩国老年人患大肠癌的风险]。
Hwa Jung Kim, Seung-Mi Lee, Nam-Kyong Choi, Seon Ha Kim, Hong-Ji Song, Young Kyun Cho, Byung-Joo Park
{"title":"[Smoking and colorectal cancer risk in the Korean elderly].","authors":"Hwa Jung Kim,&nbsp;Seung-Mi Lee,&nbsp;Nam-Kyong Choi,&nbsp;Seon Ha Kim,&nbsp;Hong-Ji Song,&nbsp;Young Kyun Cho,&nbsp;Byung-Joo Park","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The incidence of colorectal cancer increased greatly among the elderly in Korea, but the relationship between smoking and colon cancer remains controversial. Few studies have targeted Asian elderly people. We analyzed the smoking status, the amount smoked, and the smoking duration as risk factors of colorectal cancer to determine their association and causality.</p><p><strong>Methods: </strong>The cohort members (n = 14,103) consisted of 4,694 males and 9,409 females, and they were derived from the Korea Elderly Phamacepidemilogic Cohort (KEPEC), which was a population-based dynamic cohort. They were aged 65 years or more and they lived in Busan Metropolitan City between from 1993-1998; they were beneficiaries of the Korean Medical Insurance Corporation (KMIC). The baseline information was surveyed by a self-administered mailed questionnaire; after 8.7 person-years of mean follow up period, 100 cases of colorectal cancer occurred. The adjusted relative ratio (aRR) of smoking status, the smoking amount and the smoking duration were calculated from the Cox's proportional hazard model with the never-smokers as a reference group and the Cox model controlled for age, gender, precancerous lesions of CRC, medication history of NSAIDs and antibiotics, the alcohol drinking status and BMI.</p><p><strong>Results: </strong>Compared with the never smokers, the aRRs were 2.03 (95% CI = 1.02-4.03) and 1.36 (95% CI = 0.80-2.32) for the ex-smokers and current smokers, respectively. Statistical significant trends were not observed for the dose-relationship among the elderly, either for the mean daily amount smoked (p for trend = 0.28) or for the total amount (p for trend = 0.15). Still, the aRRs were 1.51 (95% Cl = 0.97-2.34) for the elderly who smoked less than 40 years and 2.35 (95% CI = 1.16-4.74) for the elderly who had 40 years or more of smoking (p for trend = 0.06). Smokers who started smoking before the age 20 had an increased aRR of 2.15 (95% CI = 1.17-3.93) compared to the never smokers.</p><p><strong>Conclusions: </strong>After controlling for age, gender, precancerous lesion of CRC, medication history of NSAIDs and antibiotics, the alcohol drinking status and BMI, smoking increases the risk of colorectal cancer among elderly people. The age when starting smoking is also important.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"123-9"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25974236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Reformation of residency trainingship for the future of preventive medicine in Korea]. [韩国预防医学未来的住院医师培训改革]。
Chang Yoon Kim
{"title":"[Reformation of residency trainingship for the future of preventive medicine in Korea].","authors":"Chang Yoon Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From the start of the residency trainingship in 1963, the residency training programs have been contributed much on the establishment and development of preventive medicine in Korea. But these programs are now have several problems to update the changes in health service needs of the population that were caused by a rapid epidemiologic transition from the acute infectious diseases to chronic diseases in last a few decades. Strengthening in medical practice, not just in knowledge is urgently required. Must have more concentrate on preventive service for the individual, as in clinical preventive medicine. Training residents by the systematic and well scheduled programs, not just 'teacher's assistant' in the academic facilities. Trying the change in the system of Specilty of Preventive Medicine to the well established several subspecialty, so more specific competency can be gained through the training. These approach and reformation may not only contribute for the better future of the preventive medicine, but also improve in disease prevention and health promotion, which required by the society in Korea.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"110-4"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25974234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Estimating the cost savings due to the effect of Kremezin in delaying the initiation of dialysis treatments among patients with chronic renal failure]. [估计由于Kremezin延迟慢性肾衰竭患者开始透析治疗的效果而节省的成本]。
Hye-Young Kang, Woohyun Cho, Sunmi Lee, Hyung-Jong Kim, Ho Yong Lee, Tae-Wook Woo
{"title":"[Estimating the cost savings due to the effect of Kremezin in delaying the initiation of dialysis treatments among patients with chronic renal failure].","authors":"Hye-Young Kang,&nbsp;Woohyun Cho,&nbsp;Sunmi Lee,&nbsp;Hyung-Jong Kim,&nbsp;Ho Yong Lee,&nbsp;Tae-Wook Woo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>We wanted to evaluate the economic value of a pharmaceutical product, Kremezin, for treating patients with chronic renal failure (CRF) by estimating the amount of cost savings due to its effect for delaying the initiation of dialysis treatments.</p><p><strong>Methods: </strong>We defined a conventional treatment for CRF accompanied by Kremezin therapy as 'the treatment group' and only conventional treatment as 'the alternative group.' The types of costs included were direct medical and non-medical costs and costs of productivity loss. The information on the effect of Kremezin was obtained from the results of earlier clinical studies. Cost information was derived from the administrative data for 20 hemodialysis and 20 peritoneal dialysis patients from one tertiary care hospital, and also from the administrative data of 10 hemodialysis patients from one free-standing dialysis center. Per-capita cost savings resulting from Kremezin therapy were separately estimated for the cases with delay for the onset of hemodialysis and the cases with immediate performance of peritoneal dialysis. By computing the weighted average for the cases of hemodialysis and peritoneal dialysis, the expected per-capita cost savings of a patient with CRF was obtained. Using a discount rate of 5%, future cost savings were converted to the present value.</p><p><strong>Results: </strong>The present value of cumulative cost savings per patient with CRF from the societal perspective would be 18,555,000-29,410,000 Won or 72,104,000-112,523,000 Won if Kremezin delays the initiation of dialysis by 1 or 4 years.</p><p><strong>Conclusions: </strong>The estimated amount of cost savings resulting from treating CRF patients with Kremezin confirms that its effect for delaying the onset of dialysis treatments has a considerable economic value.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"149-58"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25974239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Glutathione S-transferases (GSTM1, GSTT1 and GSTP1) and N-acetyltransferase 2 polymorphisms and the risk of gastric cancer]. 谷胱甘肽s -转移酶(GSTM1, GSTT1和GSTP1)和n -乙酰转移酶2多态性与胃癌的风险[j]。
Su Hyung Hong, Jung Wan Kim, Ho Gak Kim, In Kyu Park, Jun Wook Ryoo, Chang Hyeong Lee, Yoon Kyung Sohn, Jong Young Lee
{"title":"[Glutathione S-transferases (GSTM1, GSTT1 and GSTP1) and N-acetyltransferase 2 polymorphisms and the risk of gastric cancer].","authors":"Su Hyung Hong,&nbsp;Jung Wan Kim,&nbsp;Ho Gak Kim,&nbsp;In Kyu Park,&nbsp;Jun Wook Ryoo,&nbsp;Chang Hyeong Lee,&nbsp;Yoon Kyung Sohn,&nbsp;Jong Young Lee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Polymorphisms of genes from glutathione S-transferases (GSTs) and N-acetyltransferase 2 (NAT2) have been associated with increased susceptibility to various cancers. Previous results showed that East Asians such as Koreans, Japanese and Chinese have a much higher frequency of the GSTM1 and GSTT1 null genotypes and NAT2 rapid acetylator type. Therefore, we investigated the association between the polymorphic types of GSTs (GSTM1, GSTT1, GSTP1) and NAT2 and the incidence of gastric cancer which is one of the most prevalent cancers among the East Asians.</p><p><strong>Methods: </strong>It was performed in a case-control study consisting of 238 healthy subjects and 108 cancer patients (54 distal and 54 proximal carcinomas). We also evaluated the association between GSTs and NAT2 and the risk factors for gastric cancer such as alcohol consumption, smoking, H. pylori infection, family history of gastric cancer, and tumor location.</p><p><strong>Results: </strong>In our study, the percentage of cases whose hometown was rural was higher than those of controls (odds ratio (OR) = 2.88; 95% CI = 1.72-4.76), and the frequency of the lower socio-economic status increased significantly in patients (OR = 2.53; 95% Cl = 1.59-4.02). There was no significant difference in the GST polymorphic types between the cases and controls. However, NAT2 rapid or intermediate acetylator types were frequently detected in the cases with family history of gastric cancer (OR = 1.92; 95% CI = 1.79-26.0).</p><p><strong>Conclusions: </strong>These results suggest that the hometown and socio-economic status are important environmental factors for gastric carcinogenesis, and NAT2 polymorphic types could be associated with familial gastric carcinoma.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"135-40"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25974237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Association analysis of the essential hypertension susceptibility genes in adolescents: Kangwha study]. 青少年原发性高血压易感基因的关联分析:Kangwha研究。
Il Suh, Chung Mo Nam, Sung-Joo Kim, Dong-Jik Shin, Nam Wook Hur, Dae Ryong Kang
{"title":"[Association analysis of the essential hypertension susceptibility genes in adolescents: Kangwha study].","authors":"Il Suh,&nbsp;Chung Mo Nam,&nbsp;Sung-Joo Kim,&nbsp;Dong-Jik Shin,&nbsp;Nam Wook Hur,&nbsp;Dae Ryong Kang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>In this study we examined the association between the genetic markers ACE (A-240T, C-93T, I/D, A2350G), AGT (M235T), AT1R (A1166C), CYP11B2 (T-344C, V386A), REN (G2646A), ADRB2 (G46A, C79G, T-47C, T164I), GNB3 (C825T) and ADD1 (G460W) and the presence of essential hypertension in adolescents.</p><p><strong>Methods: </strong>The Kangwha Study is an 18-year prospective study that is aimed at elucidating the determinants of the blood pressure level from childhood to early adulthood. For this study, we constructed a case-control dataset of size of 277 and 40 family trios data from the Kangwha Study. For this purpose, we perform a single locus-based case-control association study and a single locus-based TDT (transmission/disequilibrium test) study.</p><p><strong>Results: </strong>In the case-control study, the single locus-based association study indicated that the ADD1 (G460W) (p = 0.0403), AGT (M235T) (p = 0.0002), and REN (G2646A) (p = 0.0101) markers were significantly associated with the risk of hypertension. These results were not confirmed on the TDT study. This study showed that genetic polymorphisms of the ADD1, AGT and REN genes might be related to the hypertension in Korean adolescents.</p><p><strong>Conclusions: </strong>This study provided useful information on genetics markers related to blood pressure. Further study will be needed to confirm the effect of the alpha adducin gene, the angiotensinogen gene and the renin gene on essential hypertension.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"177-83"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25973511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Relationship of socioeconomic factors with medical utilization for lower urinary tract symptoms and benign prostatic hyperplasia in a South Korean community]. [社会经济因素与韩国社区下尿路症状和良性前列腺增生的医疗利用的关系]。
Han-Hae Kim, Kyoung Ae Kong, Hun Jae Lee, Hana Yoon, Bo Eun Lee, Ok-Ryun Moon, Hyesook Park
{"title":"[Relationship of socioeconomic factors with medical utilization for lower urinary tract symptoms and benign prostatic hyperplasia in a South Korean community].","authors":"Han-Hae Kim,&nbsp;Kyoung Ae Kong,&nbsp;Hun Jae Lee,&nbsp;Hana Yoon,&nbsp;Bo Eun Lee,&nbsp;Ok-Ryun Moon,&nbsp;Hyesook Park","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>We wanted to evaluate the medical underutilization for benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among Korean elderly men and we wanted to determine their associated factors.</p><p><strong>Methods: </strong>This study was conducted on 239 men with LUTS and 116 men with BPH who were compatible with the diagnostic criteria from a total of 641 participants. These participants were over 50 years old and they were randomly chosen in a community-based study for estimating the prevalence of BPH. Using a self-reported questionnaire, we surveyed the sociodemographics, health status, quality of life, lower urinary tract symptoms, medical utilization and reasons for not seeking treatment.</p><p><strong>Results: </strong>Only 27.6% of the men with LUTS and 31.0% of the men with BPH reported having visited a doctor for urinary symptoms. The reasons for not visiting a doctor were, in order of responses from the group with LUTS: 'considered the symptoms as a part of the normal ageing process', 'not enough time to visit a doctor', 'financial difficulty' and 'the symptoms were not severe or bothersome'. Regarding BPH, the responses were the same as those of the group with LUTS however, 'financial difficulty' placed second. Among the men with experience of visiting a doctor for urinary symptoms, 33.3% of those with LUTS and 28.1% of those with BPH were not treated. The most common reason in both groups was 'the symptoms were not severe to be treated'. On a multiple logistic regression analysis, the larger size household (odds ratio (OR) 3.03, 95% confidence interval (Cl) = 1.40-6.54) and an unsatisfactory quality of life related with urinary symptoms (OR 2.98, 95% CI = 1.23-7.21) were associated with medical utilization in the group of LUTS. For BPH, the current employment status was related with the medical utilization (OR 2.80, 95% CI = 1.10-7.11), in addition to the larger size household (OR 3.24, 95% CI = 1.14-9.21).</p><p><strong>Conclusions: </strong>Many men with urinary symptoms do not visit a doctor. This medical underutilization for people with LUTS and BPH may be associated with economic status in Korea.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"141-8"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25974238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Influencing factors that affect the biological monitoring of workers exposed to N,N-dimethylformamide in textile coating factories]. [影响纺织涂料厂工人接触N,N-二甲基甲酰胺生物监测的影响因素]。
In-Sung Chung, Jon-Ghan Kim, Sang-Kug Choi, Jong-Youn Bae, Mi-Young Lee
{"title":"[Influencing factors that affect the biological monitoring of workers exposed to N,N-dimethylformamide in textile coating factories].","authors":"In-Sung Chung,&nbsp;Jon-Ghan Kim,&nbsp;Sang-Kug Choi,&nbsp;Jong-Youn Bae,&nbsp;Mi-Young Lee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study is to assess the factors influencing biological monitoring of textile coating factory workers exposed to N,N-dimethylformamide (DMF).</p><p><strong>Methods: </strong>We studied 35 workers who were occupationally exposed to DMF from 9 textile coating factories. The study was carried out in two phases; summer and winter. While air concentration of DMF, temperature and humidity were assessed in order to monitor the atmospheric conditions, biological monitoring was done to determine the internal dose by analyzing the N-methylformamide (NMF) collected from urine at the beginning and end of the shift. Questionnaires and medical surveillance were also obtained during the two phases.</p><p><strong>Results: </strong>Median air concentrations of DMF in winter and summer were 1.85 ppm and 2.78 ppm respectively. Also the difference between the urinary NMF concentration at the beginning and end of the shift (delta NMF) was always significant in each season (P < 0.001). The correlations between log DMF in air, log end-of-shift urinary NMF (r = 0.555, P < 0.001) and log delta NMF (r = 0.444, P < 0.001) was statistically significant in summer. The temperature, humidity, a shift system and different styles of clothing worn were significantly different during the two phases. In a multivariate analysis, temperature and the concentration of DMF in the air were the main factors influencing biological monitoring of textile coating factory workers.</p><p><strong>Conclusions: </strong>Concerning more comprehensive prevention measures to reduce exposure for those workers occupationally exposed to DMF, dermal exposure conditions such as temperature and humidity together with the air concentration of DMF should be assessed and biological monitoring is necessary to reduce adverse health effects, especially during the summer.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"171-6"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25973510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Socioeconomic mortality inequality in Korea: mortality follow-up of the 1998 National Health and Nutrition Examination Survey (NHANES) data]. [韩国社会经济死亡率不平等:1998年全国健康和营养检查调查(NHANES)数据的死亡率随访]。
Young-Ho Khang, Hye Ryun Kim
{"title":"[Socioeconomic mortality inequality in Korea: mortality follow-up of the 1998 National Health and Nutrition Examination Survey (NHANES) data].","authors":"Young-Ho Khang,&nbsp;Hye Ryun Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>This study was conducted to examine the relationships of the several socioeconomic position indicators with the mortality risk in a representative longitudinal study of South Korea.</p><p><strong>Methods: </strong>The 1998 National Health and Nutrition Examination Survey was conducted on a cross-sectional probability sample of South Korean households, and it contained unique 13-digit personal identification numbers that were linked to the data on mortality from the National Statistical Office of Korea. Of 5,607 males and females, 264 died between 1999 and 2003. Cox's regression was used to estimate the relative risks (RR) and their 95% confidence intervals (CI) of mortality.</p><p><strong>Results: </strong>Socioeconomic differences in mortality were observed after adjustments were made for gender and age. Compared with those people having college or higher education, those people without any formal education had a greater mortality risk (RR = 2.21, 95% CI = 1.12-4.40). The mortality risk among manual workers was significantly greater than that for the non-manual workers (RR = 2.73, 95% CI = 1.47-5.06). A non-standard employment status was also associated with an increase in mortality: temporary or daily workers had a greater mortality risk than did the full-time workers (RR = 3.01, 95% CI = 1.50-6.03). The mortality risk for the low occupational class was 3.06 times greater than that of the high and middle occupational classes (95% Cl = 1.75-5.36). In addition, graded mortality differences according to equivalized monthly household income were found. A reduction of monthly household income by 500 thousand Korean Won (about 400 US dollars) was related with a 20% excess risk of mortality. Self-reported poor living standards were also associated with an increased risk of mortality. Those without health insurance had a 3.63 times greater risk of mortality than the insured (95% CI = 1.61-8.19).</p><p><strong>Conclusions: </strong>This study showed the socioeconomic differentials in mortality in a national longitudinal study of South Korea. The existence of socioeconomic mortality inequalities requires increased social discussion on social policies in Korean society. Furthermore, the mechanisms for the socioeconomic inequalities of mortality need to be explored in future studies.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"115-22"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25974235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of Fourier transform near-infrared spectrometer for determination of oxalate in standard urinary solution]. 傅立叶变换近红外光谱仪测定标准尿液中草酸盐的评价
Yeong Eun Kim, Su Hyung Hong, Jung Wan Kim, Jong Young Lee
{"title":"[Evaluation of Fourier transform near-infrared spectrometer for determination of oxalate in standard urinary solution].","authors":"Yeong Eun Kim,&nbsp;Su Hyung Hong,&nbsp;Jung Wan Kim,&nbsp;Jong Young Lee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The determination of oxalate in urine is required for the diagnosis and treatment of primary hyperoxaluria, idiopathic stone disease and various intestinal diseases. We examined the possibility of using Fourier transform near-infrared (FT-NIR) spectroscopy analysis to quantitate urinary oxalate. The practical advantages of this method include ease of the sample preparation and operation technique, the absence of sample pre-treatments, rapid determination and non-invasiveness.</p><p><strong>Methods: </strong>The range of oxalate concentration in standard urine solutions was 0-221 mg/l. These 80 different samples were scanned in the region of 780-1,300 nm with a 0.5 nm data interval by a Spectrum One NTS FT-NIR spectrometer. PCR, PLSR and MLR regression models were used to calculate and evaluate the calibration equation.</p><p><strong>Results: </strong>The PCR and PLSR calibration models were obtained from the spectral data and they are exactly same. The standard error of estimation (SEE) and the % variance were 10.34 mg/l and 97.86%, respectively. After full cross validation of this model, the standard error of estimation was 5.278 mg/l, which was much smaller than that of the pre-validation. Furthermore, the MCC (multiple correlation coefficient) was 0.998, which was compatible with the 0.923 or 0.999 obtained from the previous enzymatic methods.</p><p><strong>Conclusions: </strong>These results showed that FT-NIR spectroscopy can be used for rapid determination of the concentration of oxalate in human urine samples.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"165-70"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25973509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Future of scientific research on preventive medicine in Korea]. [韩国预防医学科学研究的未来]。
Hyun-Sul Lim
{"title":"[Future of scientific research on preventive medicine in Korea].","authors":"Hyun-Sul Lim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Korean Society of Preventive Medicine has undergone continuous development, after overcoming the difficult early years, in the 59 years since its establishment in 1947. It has repeatedly upgraded its quality and quantity of research with the first journal edition in 1968 and the continuous increase in publication numbers, scientific articles, joint research projects, intra-field exchanges and participation in various international scientific activities. In the future, we should gather a more extensive collection of opinions regarding the introduction of clinical preventive medicine specialists and prepare for the establishment of a training program for clinical specialists into a preventive medicine residency course. Moreover, we should raise interest in the importance of protecting individual information and maintaining medicine ethics. It's impossible to develop academic activities without cooperation. We need such cooperation with basic medical approaches across a wide range of fields. Furthermore, we should strengthen our cooperation with aspects of clinical and drug epidemiology in many fields including public health, statistics, and dietetics. Finally, we should raise the level of international cooperation with many countries, including North Korea, to prevent diseases and promote health. Preventive medicine is a science in which practice is as important as theory. We must aim to nurture preventive medicine specialists who practice in many areas of society with the goal of preventing diseases, promoting health, improving fertility, and securing healthy elderly life for individuals and the entire population. To this end, we will endeavor to promote both theoretical and practical components of academic development.</p>","PeriodicalId":520687,"journal":{"name":"Journal of preventive medicine and public health = Yebang Uihakhoe chi","volume":" ","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25973703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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