Journal of periodontal & implant science最新文献

{"title":"3D printing technology for periodontal complex neogenesis in regenerative medicine.","authors":"Chan Ho Park","doi":"10.5051/jpis.225204edi01","DOIUrl":"https://doi.org/10.5051/jpis.225204edi01","url":null,"abstract":"Hull, who invented and patented stereolithography, various types of additive manufacturing systems have been developed, such as fused deposition modeling using thermoplastics, selective laser sintering or selective laser melting (SLM) with a high-energy laser source and powder materials, and digital light processing by light curing technology, as well as different materials (e.g., polymers, metals or metallic alloys, and ceramics) in order to create rapid-prototyping models. Although the SLM process was introduced to manufacture dental products in the early 2000s, conventional methods based on dental impression techniques, including computer numerical control milling systems, have continued to be utilized for dental prostheses because newer methods have limitations for the clinical acceptability of fabricated dental prostheses. Moreover, 3D printing techniques have recently received attention due to improvements in the quality of high-resolution medical images from intra-oral scanners or cone-beam computed tomography, which have enabled rapid, highly accurate, and reproducible manufacturing of digitized models with micron-scale architectures. Consequently, temporary crowns, splints, implant surgical guides, or different dental prostheses can now be fabricated as tissue replacements or disposable devices.","PeriodicalId":520685,"journal":{"name":"Journal of periodontal & implant science","volume":" ","pages":"259-260"},"PeriodicalIF":1.9,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/a8/jpis-52-259.PMC9436645.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40337049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subgingival microbiome in periodontitis and type 2 diabetes mellitus: an exploratory study using metagenomic sequencing.","authors":"Xianjun Lu,&nbsp;Tingjun Liu,&nbsp;Jiani Zhou,&nbsp;Jia Liu,&nbsp;Zijian Yuan,&nbsp;Lihong Guo","doi":"10.5051/jpis.2103460173","DOIUrl":"https://doi.org/10.5051/jpis.2103460173","url":null,"abstract":"<p><strong>Purpose: </strong>To explore differences in the subgingival microbiome according to the presence of periodontitis and/or type 2 diabetes mellitus (T2D), a metagenomic sequencing analysis of the subgingival microbiome was performed.</p><p><strong>Methods: </strong>Twelve participants were divided into 4 groups based on their health conditions (periodontitis, T2D, T2D complicated with periodontitis, and generally healthy). Subgingival plaque was collected for metagenomic sequencing, and gingival crevicular fluids were collected to analyze the concentrations of short-chain fatty acids.</p><p><strong>Results: </strong>The shifts in the subgingival flora from the healthy to periodontitis states were less prominent in T2D subjects than in subjects without T2D. The pentose and glucuronate interconversion, fructose and mannose metabolism, and galactose metabolism pathways were enriched in the periodontitis state, while the phosphotransferase system, lipopolysaccharide (LPS) and peptidoglycan biosynthesis, bacterial secretion system, sulfur metabolism, and glycolysis pathways were enriched in the T2D state. Multiple genes whose expression was upregulated from the red and orange complex bacterial genomes were associated with bacterial biofilm formation and pathogenicity. The concentrations of propionic acid and butyric acid were significantly higher in subjects with periodontitis, with or without T2D, than in healthy subjects.</p><p><strong>Conclusions: </strong>T2D patients are more susceptible to the presence of periodontal pathogens and have a higher risk of developing periodontitis. The pentose and glucuronate interconversion, fructose and mannose metabolism, galactose metabolism, and glycolysis pathways may represent the potential microbial functional association between periodontitis and T2D, and butyric acid may play an important role in the interaction between these 2 diseases. The enrichment of the LPS and peptidoglycan biosynthesis, bacterial secretion system, and sulfur metabolism pathways may cause T2D patients to be more susceptible to periodontitis.</p>","PeriodicalId":520685,"journal":{"name":"Journal of periodontal & implant science","volume":" ","pages":"282-297"},"PeriodicalIF":1.9,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/98/jpis-52-282.PMC9436641.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of hard-type crosslinked hyaluronic acid with particulate bone substitute on bone regeneration: positive or negative?","authors":"Junseob Yun,&nbsp;Jungwon Lee,&nbsp;Sungtae Kim,&nbsp;Ki-Tae Koo,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee","doi":"10.5051/jpis.2104700235","DOIUrl":"https://doi.org/10.5051/jpis.2104700235","url":null,"abstract":"<p><strong>Purpose: </strong>The role of hard-type crosslinked hyaluronic acid (HA) with particulate bone substitutes in bone regeneration for combined inlay-onlay grafts has not been fully investigated. We aimed to evaluate the effect of hard-type crosslinked HA used with bone substitute in terms of new bone formation and space maintenance.</p><p><strong>Methods: </strong>A 15-mm-diameter round defect was formed in the calvaria of 30 New Zealand White rabbits. All animals were randomly assigned to 1 of 3 groups: the control group (spontaneous healing without material, n=10), the biphasic calcium phosphate (BCP) graft group (BCP, n=10), and the BCP graft with HA group (BCP/HA, n=10). The animals were evaluated 4 and 12 weeks after surgery. Half of the animals from each group were sacrificed at 4 and 12 weeks after surgery. Samples were evaluated using micro-computed tomography, histology, and histomorphometry.</p><p><strong>Results: </strong>The BCP group showed higher bone volume/tissue volume (BV/TV) values than the control and BCP/HA groups at both 4 and 12 weeks. The BCP and BCP/HA groups showed higher bone surface/tissue volume (BS/TV) values than the control group at both 4 and 12 weeks. The BCP group showed higher BS/TV values than the control and BCP/HA groups at both 4 and 12 weeks. No statistically significant difference in newly formed bone was found among the 3 groups at 4 weeks. The BCP group showed significantly higher new bone formation than the BCP/HA group at 12 weeks.</p><p><strong>Conclusions: </strong>Hard-type crosslinked HA did not show a positive effect on new bone formation and space maintenance. The negative effect of hard-type crosslinked HA may be due to the physical properties of HA that impede osteogenic potential.</p>","PeriodicalId":520685,"journal":{"name":"Journal of periodontal & implant science","volume":" ","pages":"312-324"},"PeriodicalIF":1.9,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/df/jpis-52-312.PMC9436643.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the size of the bony access window and the collagen barrier over the window in sinus floor elevation: a preclinical investigation in a rabbit sinus model.","authors":"Jeong-Eun Sim,&nbsp;Sangyup Kim,&nbsp;Ji-Youn Hong,&nbsp;Seung-Il Shin,&nbsp;Jong-Hyuk Chung,&nbsp;Hyun-Chang Lim","doi":"10.5051/jpis.2105560278","DOIUrl":"https://doi.org/10.5051/jpis.2105560278","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the effect of (1) the size of the bony access window and (2) collagen membrane coverage over the window in sinus floor elevation in a rabbit sinus model.</p><p><strong>Methods: </strong>Small bony access windows (SW; ø 2.8 mm) were made in 6 rabbits and large windows (LW; ø 6 mm) in 6 other rabbits. Both sinuses in each rabbit were allocated to groups with or without coverage of a collagen membrane (CM) on the window, resulting in 4 groups: SW, LW, SW+CM, and LW+CM. After 4 weeks of healing, micro-computed tomographic, histologic, and histomorphometric analyses were performed.</p><p><strong>Results: </strong>Bony healing in the window area was incomplete in all groups, but most bone graft particles were well confined in the augmented cavity. Histologically, the pattern of new bone formation was similar in all groups. Histomorphometrically, the percentage of newly formed bone was greater in the groups with CM than in the groups without CM, and in the groups with SW than in the groups with LW (12.92%±6.40% in the SW+CM group, 4.21%±7.73% in the SW group, 10.45%±4.81% in the LW+CM group, 11.77%±3.83% in the LW group). The above differences were not statistically significant (<i>P></i>0.05).</p><p><strong>Conclusions: </strong>The combination of a small bony access window and the use of a collagen membrane over the window favored new bone formation compared to other groups, but this result should be further investigated due to the limitations of the present animal model.</p>","PeriodicalId":520685,"journal":{"name":"Journal of periodontal & implant science","volume":" ","pages":"325-337"},"PeriodicalIF":1.9,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b5/ea/jpis-52-325.PMC9436639.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal granulation tissue preservation in surgical periodontal disease treatment: a pilot prospective cohort study.","authors":"Jose A Moreno Rodríguez,&nbsp;Antonio J Ortiz Ruiz","doi":"10.5051/jpis.2105780289","DOIUrl":"https://doi.org/10.5051/jpis.2105780289","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the clinical outcomes of periodontal granulation tissue preservation (PGTP) in access flap periodontal surgery.</p><p><strong>Methods: </strong>Twenty patients (stage III-IV periodontitis) with 42 deep periodontal pockets that did not resolve after non-surgical treatment were consecutively recruited. Access flap periodontal surgery was modified using PGTP. The clinical periodontal parameters were evaluated at 9 months. The differences in the amount of granulation tissue width (GTw) preserved were evaluated and the influence of smoking was analyzed.</p><p><strong>Results: </strong>GTw >1 mm was observed in 97.6% of interproximal defects, and the granulation tissue extended above the bone peak in 71.4% of defects. At 9 months, probing pocket depth reduction (4.33±1.43 mm) and clinical attachment gain (CAG; 4.10±1.75 mm) were statistically significant (<i>P</i><0.001). The residual probing depth was 3.2±0.89 mm. When GTw extended above the interproximal bone peak (i.e., the interproximal supra-alveolar granulation tissue thickness [iSUPRA-GT] was greater than 0 mm), a significant CAG was recorded in the supra-alveolar component (1.67±1.32 mm, <i>P</i><0.001). Interproximal gingival recession (iGR) was significant (<i>P</i><0.05) only in smokers, with a reduction in the interdental papillary tissue height of 0.93±0.76 mm. In non-smokers, there was no increase in the iGR when the iSUPRA-GT was >0 mm. The clinical results in smokers were significantly worse.</p><p><strong>Conclusions: </strong>PGTP was used to modify access flap periodontal surgery by preserving affected tissues with the potential for recovery. The results show that preserving periodontal granulation tissue is an effective and conservative procedure in the surgical treatment of periodontal disease.</p>","PeriodicalId":520685,"journal":{"name":"Journal of periodontal & implant science","volume":" ","pages":"298-311"},"PeriodicalIF":1.9,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/e9/jpis-52-298.PMC9436644.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of lattice versus solid structure of 3D-printed multiroot dental implants using Ti-6Al-4V: a preclinical pilot study.","authors":"Jungwon Lee,&nbsp;Ling Li,&nbsp;Hyun-Young Song,&nbsp;Min-Jung Son,&nbsp;Yong-Moo Lee,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2105720286","DOIUrl":"https://doi.org/10.5051/jpis.2105720286","url":null,"abstract":"<p><strong>Purpose: </strong>Various studies have investigated 3-dimensional (3D)-printed implants using Ti-6Al-4V powder; however, multi-root 3D-printed implants have not been fully investigated. The purpose of this study was to explore the stability of multirooted 3D-printed implants with lattice and solid structures. The secondary outcomes were comparisons between the 2 types of 3D-printed implants in micro-computed tomographic and histological analyses.</p><p><strong>Methods: </strong>Lattice- and solid-type 3D-printed implants for the left and right mandibular third premolars in beagle dogs were fabricated. Four implants in each group were placed immediately following tooth extraction. Implant stability measurement and periapical X-rays were performed every 2 weeks for 12 weeks. Peri-implant bone volume/tissue volume (BV/TV) and bone mineral density (BMD) were measured by micro-computed tomography. Bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were measured in histomorphometric analyses.</p><p><strong>Results: </strong>All 4 lattice-type 3D-printed implants survived. Three solid-type 3D-printed implants were removed before the planned sacrifice date due to implant mobility. A slight, gradual increase in implant stability values from implant surgery to 4 weeks after surgery was observed in the lattice-type 3D-printed implants. The marginal bone change of the surviving solid-type 3D-printed implant was approximately 5 mm, whereas the value was approximately 2 mm in the lattice-type 3D-printed implants. BV/TV and BMD in the lattice type 3D-printed implants were similar to those in the surviving solid-type implant. However, BIC and BAFO were lower in the surviving solid-type 3D-printed implant than in the lattice-type 3D-printed implants.</p><p><strong>Conclusions: </strong>Within the limits of this preclinical study, 3D-printed implants of double-rooted teeth showed high primary stability. However, 3D-printed implants with interlocking structures such as lattices might provide high secondary stability and successful osseointegration.</p>","PeriodicalId":520685,"journal":{"name":"Journal of periodontal & implant science","volume":" ","pages":"338-350"},"PeriodicalIF":1.9,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/65/jpis-52-338.PMC9436642.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40336504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}