Zeitschrift fur Herz Thorax und Gefasschirurgie最新文献_第3页

Als Chirurg im Einsatz für Ärzte ohne Grenzen 我是无国界医生组织的外科医生

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-05-25 DOI: 10.1007/s00398-022-00502-0

Veit Busam, Sophie-Louise Gregull

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ECMO-Kanülierung bei COVID-19

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-04-26 DOI: 10.1007/s00398-022-00504-y

M. B. Immohr, Vincent Hettlich, T. Brandenburger, D. Kindgen-Milles, Torsten Feldt, I. Tudorache, P. Akhyari, H. Aubin, Hannan Dalyanoglu, A. Lichtenberg, U. Boeken

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„Science diplomacy“ ein gescheiterter Traum? 科学硕士失败的梦想

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-03-22 DOI: 10.1007/s00398-022-00497-8

A. Welz

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Aktueller Stand der Transplantationsmedizin im Bereich Herz- und Lungentransplantation 移植心脏和肺移植的最新进展

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-03-08 DOI: 10.1007/s00398-022-00493-y

Heidi Niehaus, A. Haverich, Fabio Ius

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[CARL-Controlled reperfusion of the whole body]. [卡尔控制全身再灌注]。

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-01-01 Epub Date: 2022-02-18 DOI: 10.1007/s00398-022-00491-0

C Benk, G Trummer, J-S Pooth, C Scherer, F Beyersdorf

{"title":"[CARL-Controlled reperfusion of the whole body].","authors":"C Benk, G Trummer, J-S Pooth, C Scherer, F Beyersdorf","doi":"10.1007/s00398-022-00491-0","DOIUrl":"https://doi.org/10.1007/s00398-022-00491-0","url":null,"abstract":"Background: The incidence and mortality of acute cardiovascular arrest have been consistently high for decades.Objective: How to improve the currently unsatisfactory outcome after resuscitation regarding survival and neurological, especially cerebral, sequelae?Material and methods: Development of a therapeutic approach to curtail ischemia/reperfusion injury in an animal model. Development of a device system optimized for resuscitation that can be used to implement controlled reperfusion of the whole body outside the hospital.Results: Establishment of CARL treatment in the clinic and in the treatment of OHCA patients. Transfer of the CARL treatment and system in a clinical observational study. First case reports in which patients survived OHCA without brain damage even after ischemia times up to 2 h.Conclusion: CARL treatment is potentially suitable to treat patients suffering from cardiovascular arrest refractory to treatment even for prolonged periods.","PeriodicalId":52066,"journal":{"name":"Zeitschrift fur Herz Thorax und Gefasschirurgie","volume":"36 2","pages":"100-106"},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39944633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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[Impact of the COVID-19 pandemic on cardiac surgery]. [COVID-19大流行对心脏外科的影响]。

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-01-01 Epub Date: 2022-09-21 DOI: 10.1007/s00398-022-00539-1

Udo Boeken, Torulv Holst, Vincent Hettlich, Hilmar Dörge, Andreas Böning, Artur Lichtenberg

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[Development of cardiac surgery in the last six decades]. [过去60年心脏外科的发展]。

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-01-01 Epub Date: 2021-12-20 DOI: 10.1007/s00398-021-00475-6

Hug Aubin, Artur Lichtenberg, Udo Boeken

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[COVID-19 after heart transplantation: experiences from a German transplantation center]. [心脏移植后COVID-19:来自德国移植中心的经验]。

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-01-01 Epub Date: 2022-07-20 DOI: 10.1007/s00398-022-00529-3

Daniel Oehler, Raphael Romano Bruno, Hans Torulv Holst, Igor Tudorache, Hug Aubin, Dennis Sigetti, Patrick Horn, Payam Akhyari, Malte Kelm, Artur Lichtenberg, Ralf Westenfeld, Udo Boeken

{"title":"[COVID-19 after heart transplantation: experiences from a German transplantation center].","authors":"Daniel Oehler, Raphael Romano Bruno, Hans Torulv Holst, Igor Tudorache, Hug Aubin, Dennis Sigetti, Patrick Horn, Payam Akhyari, Malte Kelm, Artur Lichtenberg, Ralf Westenfeld, Udo Boeken","doi":"10.1007/s00398-022-00529-3","DOIUrl":"https://doi.org/10.1007/s00398-022-00529-3","url":null,"abstract":"Background: The pandemic caused by SARS-CoV‑2 (severe acute respiratory syndrome coronavirus type 2) has led to hospitalizations and increased mortality worldwide. With potentially high prevalence and severity of COVID-19 in cardiac transplantation, there is a great need to generate data in this at-risk cohort.Objective: We report here our experience with COVID-19 (coronavirus disease 2019) in heart transplant recipients at a German transplantation center longitudinally over the previous pandemic waves and place it in context to published experiences of other centers.Material and methods: All adult patients who had received a heart transplant at our center and had confirmed COVID-19 infection (n = 12) were included and retrospectively characterized.Results: The mean age was 61.5 (49-63) years, and the majority were male (83%). Comorbidities such as diabetes (42%), arterial hypertension (43%), and chronic renal failure (67%) were found. Passive immunization (convalescent plasma/monoclonal antibodies) was performed in 50%. Oxygen administration was required in 33% of patients; only one patient required noninvasive ventilation (8%), and no patient required invasive ventilation or mechanical cardiovascular support (ECMO). No new cardiovascular or thromboembolic events were found.Conclusion: We could longitudinally not detect severe courses or increased mortality of COVID-19 in heart transplant patients. Prospective studies are needed to make better prognostic estimates of COVID-19 in (heart) transplant patients in the future.","PeriodicalId":52066,"journal":{"name":"Zeitschrift fur Herz Thorax und Gefasschirurgie","volume":"36 6","pages":"406-413"},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40535133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Algorithm for action: ECMO/ECLS in SARS-CoV-2 disease]. [行动算法:SARS-CoV-2疾病的ECMO/ECLS]。

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-01-01 Epub Date: 2022-02-01 DOI: 10.1007/s00398-021-00483-6

Udo Boeken, Payam Akhyari, Andreas Beckmann

引用次数: 0

[Cardiac cell therapy-Lost in translation?] [心脏细胞疗法--翻译中的迷失？］

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Zeitschrift fur Herz Thorax und Gefasschirurgie Pub Date : 2022-01-01 Epub Date: 2022-01-05 DOI: 10.1007/s00398-021-00476-5

Christof Stamm

{"title":"[Cardiac cell therapy-Lost in translation?]","authors":"Christof Stamm","doi":"10.1007/s00398-021-00476-5","DOIUrl":"10.1007/s00398-021-00476-5","url":null,"abstract":"Cardiac cell therapy covers more than two decades of tumultuous history. In this period of time, the perception of the heart as an organ consisting of a fixed number of terminally differentiated cardiomyocytes fundamentally changed. Suddenly, the myocardium was (or is) considered to be regenerative by intrinsic progenitor cells, inducible proliferation, and in particular by exogenic transplanted cells. While the clinical translation of real cardiomyocytes obtained by cellular reprogramming has progressed only slowly, a multitude of clinical studies were carried out with cell products of somatic origin. This was mostly based on assumptions and experimentally acquired data with respect to the plasticity of adult precursor cells that, in retrospect, lacked validity. Accordingly, on closer inspection the results of the clinical studies were not convincing but they were nevertheless often presented and viewed in a very optimistic light. Today, cardiac cell therapy with cells of a somatic origin is considered to have failed. Recapitulating the stages of this era can help recognize and avoid such undesirable developments in the future.","PeriodicalId":52066,"journal":{"name":"Zeitschrift fur Herz Thorax und Gefasschirurgie","volume":"36 2","pages":"107-114"},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39922637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0