Internal medicine (Tokyo, Japan)最新文献

SARS-CoV-2 Infection in Sjögren Syndrome can be Complicated by Myelitis and Guillain-Barre Syndrome. SARS-CoV-2感染Sjögren综合征可并发脊髓炎和格林-巴利综合征。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5784-25

Josef Finsterer

引用次数: 0

Primary Hyperparathyroidism with Severe Vitamin D Deficiency in Chronic Kidney Disease. 慢性肾病伴严重维生素D缺乏的原发性甲状旁腺功能亢进。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5467-25

Tsuyoshi Oshiro, Hiroki Nishiwaki, Reiji Takami, Shinya Omiya, Edward Barroga, Fumihiko Koiwa

引用次数: 0

Asymptomatic Hiatal Hernia with Omentum and Small Bowel Herniation. 无症状裂孔疝伴大网膜及小肠疝。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5471-25

Hiroaki Mastumoto, Gen Ohara, Hiroaki Satoh

引用次数: 0

Response to SARS-CoV-2 Infection in Sjögren Syndrome can be Complicated by Myelitis and Guillain-Barré Syndrome. Sjögren综合征患者对SARS-CoV-2感染的反应可并发脊髓炎和格林-巴- <s:1>综合征

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5826-25

Takumi Funakoshi, Minoru Yamada, Kazuna Ikeda, Kazuki Yokokawa, Tarou Saito, Reiko Tsuda, Naotoshi Iwahara, Syuuichirou Suzuki, Shin Hisahara

引用次数: 0

Impact of Switching to New ResMed Devices on Continuous Positive Airway Pressure Therapy: A Multicenter Study. 切换到新的ResMed设备对持续气道正压治疗的影响：一项多中心研究。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5376-25

Satoshi Hamada, Michiko Tsuchiya, Nobuhiro Shibata, Tsuguru Hatta, Fuyuko Hatta, Jumpei Togawa, Hironobu Sunadome, Kimihiko Murase, Yukio Nagasaka, Toyohiro Hirai, Susumu Sato

{"title":"Impact of Switching to New ResMed Devices on Continuous Positive Airway Pressure Therapy: A Multicenter Study.","authors":"Satoshi Hamada, Michiko Tsuchiya, Nobuhiro Shibata, Tsuguru Hatta, Fuyuko Hatta, Jumpei Togawa, Hironobu Sunadome, Kimihiko Murase, Yukio Nagasaka, Toyohiro Hirai, Susumu Sato","doi":"10.2169/internalmedicine.5376-25","DOIUrl":"https://doi.org/10.2169/internalmedicine.5376-25","url":null,"abstract":"Purpose ResMed Inc. has recently developed new continuous positive airway pressure (CPAP) devices, namely the AirSense 11 series. This study aimed to determine whether new ResMed devices have a more favorable impact on CPAP therapy than previous models. Methods This prospective multicenter study was conducted at Kyoto University Hospital, Rakuwakai Otowa Hospital, Shibata Clinic, and Hatta Medical Clinic. Patients with sleep apnea syndrome who used the previous generation of ResMed devices and switched to new ResMed devices from April 2023 to June 2024 were eligible to participate in the study. CPAP device data for one month before and after switching to new ResMed devices were downloaded using ResScan, NemLink, or f'Rens. Results A total of 102 patients were included in this analysis. The switch from old to new ResMed devices resulted in significant decreases in median CPAP pressure and 95th percentile leak from 8.1 (6.8-9.9) cmH2O to 7.4 (6.2-8.8) cmH2O (p<0.0001) and from 25.2 (14.4-36.2) L/min to 21.9 (14.4-33.8) L/min (p=0.0034), respectively. The percentage of CPAP therapy used for at least 4 h increased from 86% (56.1%-94.3%) to 90% (60-100%) (p=0.0043). Meanwhile, the switch to new ResMed devices did not affect the apnea-hypopnea index (1.7 [0.9-2.9] events/h vs. 1.3 [0.7-2.6] events/h, p=0.092). Conclusion The New ResMed device had favorable effects on CPAP therapy. The effects of different devices from the same manufacturers, as well as those from different manufacturers, on CPAP therapy should be carefully investigated.","PeriodicalId":520650,"journal":{"name":"Internal medicine (Tokyo, Japan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Presence or Absence of Household Members is a Factor that Influences Treatment Decisions in Patients with Pancreatic Cancer. 家庭成员的存在与否是影响胰腺癌患者治疗决策的一个因素。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5533-25

Yuki Sato, Kenichi Takahashi, Masaki Aokawa, Shinichiro Minami, Mitsuru Chiba, Wataru Sato, Takashi Goto, Katsunori Iijima

{"title":"The Presence or Absence of Household Members is a Factor that Influences Treatment Decisions in Patients with Pancreatic Cancer.","authors":"Yuki Sato, Kenichi Takahashi, Masaki Aokawa, Shinichiro Minami, Mitsuru Chiba, Wataru Sato, Takashi Goto, Katsunori Iijima","doi":"10.2169/internalmedicine.5533-25","DOIUrl":"https://doi.org/10.2169/internalmedicine.5533-25","url":null,"abstract":"Objective Although marital status has been demonstrated to affect patients' decisions to undergo active treatment for pancreatic cancer (PC), the role of other household cohabitants remains uncertain. This study aimed to examine whether the presence or absence of other household cohabitants, apart from spouses, affects the treatment decisions of patients with PC. Methods and Patients A retrospective analysis of patients diagnosed with PC at the Akita University Hospital between January 2014 and December 2020 was conducted. Information about the patients' backgrounds, including the number of persons residing in their households, was gathered. A multivariate regression analysis was conducted to ascertain the factors associated with patients' decisions to undergo aggressive treatment, such as surgery, chemotherapy, and radiotherapy. Results A total of 214 patients with histopathologically confirmed PC were enrolled in this study. Those who lived with others were more likely to receive aggressive treatment than those who lived alone (84.9% vs. 54.5%; p<0.01). The multivariate analysis, adjusted for patients' age, performance status, and marital status indicated that the patient's decision to undergo aggressive treatment was found to be positively associated with living with other household members with an odds ratio (95% confidence interval): 4.5 (1.02-19.9), p<0.05. Conclusion Our findings indicate that the influence of cancer treatment decisions extends beyond that of spouses to encompass other household cohabitation members. By providing comprehensive social and emotional assistance to patients residing in isolation, it is possible to facilitate active treatment and enhance the prognosis for patients with PC.","PeriodicalId":520650,"journal":{"name":"Internal medicine (Tokyo, Japan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autonomic Dysfunction in Miller Fisher Syndrome: A Case of Paralytic Ileus and Isolated Internal Ophthalmoplegia. 米勒费雪综合征的自主神经功能障碍：麻痹性肠梗阻和孤立性内眼麻痹1例。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5523-25

Nobuyuki Ishii, Miyuki Miyamoto

引用次数: 0

Two Cases of Autosomal Recessive Spinocerebellar Ataxia-8 Showing Two Novel Variants of SYNE1 in Japanese Families. 两例常染色体隐性脊髓小脑共济失调-8显示日本家庭中SYNE1的两种新变体。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5602-25

Taijun Yunoki, Chika Matsuoka, Yosuke Osakada, Yusuke Fukui, Mami Takemoto, Ryuta Morihara, Toru Yamashita, Hiroyuki Ishiura

引用次数: 0

A Retrospective Observational Study of Otitis Media with Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis. 中耳炎合并抗中性粒细胞细胞质抗体相关血管炎的回顾性观察研究。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5058-24

Natsumi Nagao, Yu Funakubo Asanuma, Tomoyasu Kitahara, Han Matsuda, Yuji Akiyama, Tetsuo Ikezono, Toshihide Mimura

{"title":"A Retrospective Observational Study of Otitis Media with Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis.","authors":"Natsumi Nagao, Yu Funakubo Asanuma, Tomoyasu Kitahara, Han Matsuda, Yuji Akiyama, Tetsuo Ikezono, Toshihide Mimura","doi":"10.2169/internalmedicine.5058-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.5058-24","url":null,"abstract":"Objective This study aimed to clarify the clinical features and effective treatments for localized otitis media-associated vasculitis (OMAAV). Methods We conducted a single-center retrospective study, classifying the patients into localized OMAAV and systemic OMAAV groups, based on the OMAAV diagnostic criteria, and compared their clinical features, laboratory findings, clinical course, treatment, and hearing prognosis. We also assessed any tympanic membrane findings suggestive of vasculitis using the scoring system of the OMAAV tympanic membrane (SCOT). Results We collected data from 20 OMAAV patients between January 2013 and July 2023. Seventy percent of the patients visited the otolaryngology department as their first consultation, with a median period of 2.5 months from the onset of ear symptoms to diagnosis. Compared to systemic OMAAV, localized OMAAV had fewer systemic symptoms, such as high fever, and the markers of inflammation were also lower. The positivity rate of ANCA was similar between the groups, and 90% of the cases with localized OMAAV were positive for MPO-ANCA. The combination rate of glucocorticoids (GC) and immunosuppressants (IS) in localized OMAAV was high (80%), and the initial dosage of GC was similar to that in systemic OMAAV. Regarding the treatment outcomes, the rate of hearing improvement was high at 75%, and no patients experienced a relapse of localized OMAAV. Conclusion An early diagnosis of localized OMAAV requires the recognition of tympanic membrane findings suggestive of vasculitis and measurement of the ANCA levels. Early aggressive treatment with GC and IS for localized OMAAV can lead to a favorable hearing prognosis.","PeriodicalId":520650,"journal":{"name":"Internal medicine (Tokyo, Japan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psoriasis Vulgaris on Hemodialysis Patient's Arteriovenous Fistula. 寻常型银屑病对血液透析患者动静脉瘘的影响。

Internal medicine (Tokyo, Japan) Pub Date : 2025-06-05 DOI: 10.2169/internalmedicine.5768-25

Miya Hiramatsu, Masatoshi Inoue, Mariko Seishima, Junichiro Yamamoto

引用次数: 0