抗ro52 /SS-A抗体阳性Sjögren病患者合并多发性肌炎的心脏磁共振成像评估亚临床心肌损害

IF 1.1
Kiichi Sugito, Masashi Uchikawa, Shinya Asatani, Masahiro Nishihara, Yosuke Nagasawa, Hirotake Inomata, Masako Tsukamoto, Hitomi Kobayashi, Noboru Kitamura, Hideki Nakamura, Yasuo Okumura
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引用次数: 0

摘要

一名52岁女性因肌痛、抗氨基酰基tRNA合成酶、抗ss -A/Ro52抗体阳性、肌酸激酶水平升高而入住我院。她被诊断为Sjögren病(SjD)并多发性肌炎(PM)。未观察到胸部症状。虽然她的心电图和超声心动图结果正常,但心脏磁共振成像(CMRI)显示心肌水肿和纤维化伴晚期钆增强,细胞外体积升高,T2值升高。强的松龙治疗后,肌痛和CMRI异常有所改善。本病例提示CMRI可用于SjD合并PM患者亚临床心肌损伤的检测和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Subclinical Myocardial Involvement Evaluated by Cardiac Magnetic Resonance Imaging in a Patient with Anti-Ro52/SS-A Antibody-positive Sjögren's Disease Complicated with Polymyositis.

A 52-year-old woman with myalgia, anti-aminoacyl tRNA synthetase, anti-SS-A/Ro52 antibody positivity, and elevated creatine kinase levels was admitted to our hospital. She was diagnosed with Sjögren's disease (SjD) complicated by polymyositis (PM). No chest symptoms were observed. Although her electrocardiogram and echocardiogram findings were normal, cardiac magnetic resonance imaging (CMRI) revealed myocardial edema and fibrosis with late gadolinium enhancement, elevated extracellular volume, and elevated T2 values. After treatment with prednisolone, the myalgia and CMRI abnormalities improved. This case suggests that CMRI may be useful for the detection and treatment of subclinical myocardial damage in patients with SjD complicated by PM.

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