European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity最新文献

{"title":"Correction: Effects of functional training with blood occlusion on the irisin, follistatin, and myostatin myokines in elderly men.","authors":"Fatemeh Pazokian, Sadegh Amani-Shalamzari, Hamid Rajabi","doi":"10.1186/s11556-022-00308-x","DOIUrl":"https://doi.org/10.1186/s11556-022-00308-x","url":null,"abstract":"","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"27"},"PeriodicalIF":6.3,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40442690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Onset of the COVID-19 pandemic reduced active time in patients with implanted cardiac devices.","authors":"Nicholas Sommers,&nbsp;Marcie Berger,&nbsp;Jason C Rubenstein,&nbsp;James Roth,&nbsp;Amy Pan,&nbsp;Colton Thompson,&nbsp;Michael E Widlansky","doi":"10.1186/s11556-022-00305-0","DOIUrl":"https://doi.org/10.1186/s11556-022-00305-0","url":null,"abstract":"<p><strong>Background: </strong>Physical inactivity and sedentary behavior are modifiable risk factors for chronic disease and all-cause mortality that may have been negatively impacted by the COVID-19 shutdowns.</p><p><strong>Methods: </strong>Accelerometry data was retrospectively collected from 332 permanent pacemaker (PPM) and 244 implantable cardiac defibrillation (ICD) patients for 6 time points: March 15-May 15, 2020 (pandemic period), January 1-March 14, 2020, October 1-December 31, 2019, March 15-May 15, 2019, January 1-March 14, 2019, and October 1-December 31, 2018. Paired t-tests, with Bonferroni correction, were used to compare time periods.</p><p><strong>Results: </strong>Activity significantly decreased during the pandemic period compared to one year prior by an average of 0.53 ± 1.18h/day (P < 0.001) for PPM patients and 0.51 ± 1.2h/day (P < 0.001) for ICD patients. Stratification of subjects by active time (< 2 versus ≥ 2h/day) showed patients with < 2h, particularly those with ICDs, had modestly greater activity reductions with the pandemic onset. Logistical regression analyses suggest a trend toward a greater reduction in active time at the onset of the pandemic and an increased risk of hospital or emergency department (ED) admission for PPM patients, but not ICD patients.</p><p><strong>Conclusion: </strong>The onset of the pandemic in the United States was associated with a significant drop in PPM and ICD patient active hours that was modestly more pronounced in less active patients and cannot be explained by one year of aging or seasonal variation. If sustained, these populations may experience excess cardiovascular morbidity.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"26"},"PeriodicalIF":6.3,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40450269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Physical activity and recurrent fall risk in community-dwelling Japanese people aged 40-74 years: the Murakami cohort study.","authors":"Shoto Kamimura,&nbsp;Takashi Iida,&nbsp;Yumi Watanabe,&nbsp;Kaori Kitamura,&nbsp;Keiko Kabasawa,&nbsp;Akemi Takahashi,&nbsp;Toshiko Saito,&nbsp;Ryosaku Kobayashi,&nbsp;Rieko Oshiki,&nbsp;Ribeka Takachi,&nbsp;Shoichiro Tsugane,&nbsp;Masayuki Iki,&nbsp;Ayako Sasaki,&nbsp;Osamu Yamazaki,&nbsp;Kei Watanabe,&nbsp;Kazutoshi Nakamura","doi":"10.1186/s11556-022-00306-z","DOIUrl":"https://doi.org/10.1186/s11556-022-00306-z","url":null,"abstract":"","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"25"},"PeriodicalIF":6.3,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40679579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: An interrater reliability study of gait analysis systems with the dual task paradigm in healthy young and older adults.","authors":"Thomas Jürgen Klotzbier,&nbsp;Bettina Wollesen,&nbsp;Oliver Vogel,&nbsp;Julian Rudisch,&nbsp;Thomas Cordes,&nbsp;Thomas Jöllenbeck,&nbsp;Lutz Vogt","doi":"10.1186/s11556-022-00301-4","DOIUrl":"https://doi.org/10.1186/s11556-022-00301-4","url":null,"abstract":"","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"24"},"PeriodicalIF":6.3,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33506064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of functional training with blood occlusion on the irisin, follistatin, and myostatin myokines in elderly men.","authors":"Fatemeh Pazokian,&nbsp;Sadegh Amani-Shalamzari,&nbsp;Hamid Rajabi","doi":"10.1186/s11556-022-00303-2","DOIUrl":"https://doi.org/10.1186/s11556-022-00303-2","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to determine the efficacy of functional training with and without blood flow restriction (BFR) on muscle hypertrophy indices and strength in older men.</p><p><strong>Methods: </strong>Thirty older adults (67.7 ± 5.8 years) were randomly assigned to three groups: functional training (FT), functional training with BFR (FTBFR), and control (C). Participants in experimental groups were trained in three sessions per week for six weeks. They performed 11 whole body exercises, in 2-4 sets of 10 repetitions. FTBFR group wore pneumatic cuffs on their extremities that began with 50% of estimated arterial occlusion pressure which increased by 10% every two weeks. Blood samples were obtained, and static strength tests were evaluated at baseline and after the training program. A One-Way Analysis of Covariance was used to interpret the data.</p><p><strong>Results: </strong>A significant increase in follistatin levels (p = 0.002) and reduction in myostatin levels (p = 0.001) were observed in FT and FTBFR groups; there was a considerable increase in the F:M ratio in both training groups (p = 0.001), whereas it decreased in C group. These changes were accompanied by significant improvements in handgrip (p = 0.001) and shoulder girdle (p = 0.001) strength in both experimental groups, especially in the FTBFR group. However, the levels of irisin were not statistically changed following interventions (p = 0.561).</p><p><strong>Conclusion: </strong>The findings showed that FT was effective in increasing circulating biomarkers involved in hypertrophy in older adults while adding BFR to FT had a slight increase in these biomarkers but had a tremendous increase in muscle strength.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"22"},"PeriodicalIF":6.3,"publicationDate":"2022-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33480686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity and recurrent fall risk in community-dwelling Japanese people aged 40-74 years: the Murakami cohort study.","authors":"Shoto Kamimura,&nbsp;Takashi Iida,&nbsp;Yumi Watanabe,&nbsp;Kaori Kitamura,&nbsp;Keiko Kabasawa,&nbsp;Akemi Takahashi,&nbsp;Toshiko Saito,&nbsp;Ryosaku Kobayashi,&nbsp;Rieko Oshiki,&nbsp;Ribeka Takachi,&nbsp;Shoichiro Tsugane,&nbsp;Masayuki Iki,&nbsp;Ayako Sasaki,&nbsp;Osamu Yamazaki,&nbsp;Kei Watanabe,&nbsp;Kazutoshi Nakamura","doi":"10.1186/s11556-022-00300-5","DOIUrl":"https://doi.org/10.1186/s11556-022-00300-5","url":null,"abstract":"<p><strong>Background: </strong>Falls are important causes of injury and mortality in older people, and associated medical costs can be enormous. Physical activity (PA) is a potential preventive factor for falls. However, few studies have examined the effect of different types of PA on fall prevention. This study aimed to evaluate the association between PA levels and the incidence of recurrent falls by type of PA in middle-aged and older people.</p><p><strong>Methods: </strong>This cohort study targeted 7,561 community-dwelling individuals aged 40-74 years who did not experience recurrent falls in the year before baseline. Information on PA levels, demographics, body size, lifestyle, and fall/disease history was obtained using a self-administered questionnaire in the baseline survey. Levels of total PA, leisure-time PA, and non-leisure-time PA (occupation, commuting, and housework) were estimated using metabolic equivalent (MET) scores (MET-h/day; hours spent on a given activity per day multiplied by its MET intensity). PA levels were categorized into four groups. Falls were recorded as none, once, or twice or more (recurrent falls). The outcome of the study was the incidence of recurrent falls in the past year before a survey conducted 5 years after the baseline survey. Logistic regression analyses were performed to calculate odds ratios for recurrent falls.</p><p><strong>Results: </strong>Higher total PA and non-leisure-time PA levels were associated with a higher risk of recurrent falls (P for trend = 0.0002 and 0.0001, respectively), with the highest total PA and non-leisure-time PA groups having a significantly higher adjusted OR (1.96 [95%CI:1.33-2.88] and 2.15 [95%CI:1.48-3.14], respectively) relative to the lowest group (reference). As for leisure-time PA, the medium group had a significantly lower adjusted OR (0.70 [95%CI:0.49-0.99]) relative to the reference group. By sex, the adjusted OR in the medium leisure-time PA group was significantly lower relative to the reference group in women (0.50 [95%CI: 0.29-0.85]) but not in men.</p><p><strong>Conclusions: </strong>Medium level leisure-time PA reduces the risk of recurrent falls in middle-aged and older people, whereas higher level non-leisure-time PA is associated with a higher risk of recurrent falls.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"20"},"PeriodicalIF":6.3,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40345376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of power training compared to strength training in older adults: a systematic review and meta-analysis.","authors":"Mohamed El Hadouchi,&nbsp;Henri Kiers,&nbsp;Ralph de Vries,&nbsp;Cindy Veenhof,&nbsp;Jaap van Dieën","doi":"10.1186/s11556-022-00297-x","DOIUrl":"https://doi.org/10.1186/s11556-022-00297-x","url":null,"abstract":"<p><strong>Background: </strong>Research suggests that muscle power is a more critical determinant of physical functioning in older adults than muscle strength. The objective of this study was to systematically review the literature on the effect of power training compared to strength training in older adults on tests for muscle power, two groups of activity-based tests under controlled conditions: generic tests and tests with an emphasis on movement speed, and finally, physical activity level in daily life.</p><p><strong>Methods: </strong>A systematic search for randomized controlled trials comparing effects of power training to strength training in older adults was performed in PubMed, Embase, Ebsco/CINAHL, Ebsco/SPORTDiscus, Wiley/Cochrane Library and Scopus. Risk of bias was assessed using the Cochrane Collaboration Tool, and quality of evidence was evaluated using GRADEpro Guideline Development Tool. Standardized mean differenences (SMD) and 95% confidence intervals (CI) were calculated for outcomes separately using a random effects model.</p><p><strong>Results: </strong>Fifteen trials and 583 participants were included in the meta-analysis. Results indicated a statistically significant benefit of power training on all reported outcomes (muscle power SMD: 0.99, 95% CI: 0.54 to 1.44, p < 0.001; generic activity-based tests SMD: 0.37, 95% CI 0.06 to 0.68; p = 0.02, activity-based tests emphasizing movement speed SMD: 0.43, 95% CI 0.23 to 0.62, p < 0.001). None of the included studies used physical activity level in daily life as outcome.</p><p><strong>Conclusions: </strong>Power training offers more potential for improving muscle power and performance on activity tests in older adults compared to strength training. Future research should assess exercise parameters for power training in older adults. In addition, the validity and reliability of the tests used must be evaluated to establish a standardized test protocol. This protocol should also include measurements of physical activity in daily life.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"18"},"PeriodicalIF":6.3,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of blood flow restriction (BFR) with resistance exercise on musculoskeletal health in older adults: a narrative review.","authors":"Zi Xiang Lim,&nbsp;Jorming Goh","doi":"10.1186/s11556-022-00294-0","DOIUrl":"https://doi.org/10.1186/s11556-022-00294-0","url":null,"abstract":"<p><strong>Background: </strong>Aging leads to a number of structural and physiological deficits such as loss of muscle mass and strength. Strength training at ~ 70% of 1 repetition max (RM) is recommended to prevent age-related loss of muscle mass and strength. However, most older adults may not be able to perform 70% of 1RM or higher intensity. An alternative exercise training program combining low intensity resistance exercise with blood flow restriction (BFR) can result in similar acute and chronic benefits to skeletal muscles in older adults.</p><p><strong>Main body and short conclusion: </strong>The potential mechanisms involved are discussed, and include reactive hyperaemia, metabolic stress, and hypoxia. Key issues and safety with the use of BFR in older adults, especially those with chronic conditions are also discussed. Although there has been no reported evidence to suggest that BFR elevates the risk of clinical complications any more than high intensity exercise, it is recommended for individuals to be medically cleared of any cardiovascular risks, prior to engaging in BFR exercise.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"15"},"PeriodicalIF":6.3,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40103815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship of weather with daily physical activity and the time spent out of home in older adults from Germany - the ActiFE study.","authors":"Matthias Klimek,&nbsp;Raphael Simon Peter,&nbsp;Michael Denkinger,&nbsp;Dhayana Dallmeier,&nbsp;Kilian Rapp,&nbsp;Dietrich Rothenbacher,&nbsp;Jochen Klenk","doi":"10.1186/s11556-022-00286-0","DOIUrl":"https://doi.org/10.1186/s11556-022-00286-0","url":null,"abstract":"<p><strong>Background: </strong>There is a need for a comprehensive evaluation of the associations between varieties of weather conditions on the time spent out-of-home (TOH) and on walking duration (WD) among older adults. We aim to investigate the extent to which various weather parameters (temperature, solar radiation, sunshine duration, humidity, windspeed, and rain) determine daily WD the TOH in older adults.</p><p><strong>Methods: </strong>The ActiFE (Activity and Function in Older People in Ulm) study is a prospective study of participants aged 65 years or older who wore an accelerometer and kept a movement diary in up to three temporally separated waves from 2009 to 2018 for a duration up to seven days per wave (up to three weeks in summary). We used weather data from a weather station near the participants' homes. Age-adjusted and gender-stratified generalized mixed models were used to predict WD and TOH (with 95% confidence interval (CI)) within and between weather categories. Generalized additive models were computed for the single predictions at the weather quartile boundaries. Cubic splines (with 95% pointwise confidence bands (CB)) visualized the continuous course of the weather values.</p><p><strong>Results: </strong>Higher temperatures, solar radiation and more hours of sunshine, led to an increase in WD and TOH, while higher precipitation, humidities and windspeeds led to a decrease. Women had in general higher WD and TOH times than men.</p><p><strong>Conclusions: </strong>Our data suggest that weather parameters have a considerable influence on PA and TOH. Future analyses and interpretation of PA data should therefore account for weather parameters.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"6"},"PeriodicalIF":6.3,"publicationDate":"2022-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39913031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should knee extension strength testing be implemented as a screening test for identifying probable and confirmed sarcopenia in older T2DM patients?","authors":"Ofer Kis,&nbsp;Assaf Buch,&nbsp;Roy Eldor,&nbsp;Amir Rubin,&nbsp;Ayelet Dunsky,&nbsp;Naftali Stern,&nbsp;Daniel S Moran","doi":"10.1186/s11556-021-00280-y","DOIUrl":"https://doi.org/10.1186/s11556-021-00280-y","url":null,"abstract":"<p><strong>Background: </strong>The accelerated loss of muscle strength and mass observed in older type 2 diabetes mellitus (T2DM) patients due to the combined effects of diabetes and obesity, greatly increases their risk for sarcopenia. Early detection and treatment of probable and confirmed sarcopenia is paramount to delay mobility disability. Using low handgrip strength cut-off points for the initial identification of sarcopenia according to the new European Working Group on Sarcopenia in Older People (EWGSOP2) guidelines may mask the presence of sarcopenia. Relative knee extension strength cut-off points using a simple hand-held dynamometer can assist clinicians in the diagnosis of probable and confirmed sarcopenia by possibly reducing false negative results.</p><p><strong>Methods: </strong>A cohort of one hundred T2DM older patients (60% women) (mean age 74.5 years) mostly obese community dwelling older adults were evaluated for body composition by Bioelectrical impedance analysis (BIA), yielding appendicular skeletal mass index (ASMI) results. Patients underwent handgrip strength (HGS) and knee extension strength (KES) tests as well as functional ability tests. Prevalence of probable and confirmed sarcopenia using HGS and KES cut-off points were calculated. Pearson correlations were performed to evaluate the relationship between ASMI and limbs strength. A regression analysis was conducted to examine which variables best predict ASMI values. A multivariate analysis of covariance was performed to assess the effect of independent variables on KES and HGS.</p><p><strong>Results: </strong>Using cutoff points for low KES identified 24 patients with probable sarcopenia and two with confirmed sarcopenia. Conversely, using the EWGSOP2 cut off points for low HGS, identified only one patient with probable sarcopenia and none of the patients with confirmed sarcopenia.</p><p><strong>Conclusion: </strong>KES cut-off points using a simple hand-held dynamometer can assist in the identification of probable and confirmed sarcopenia using EWGSOP2 cut off points for low muscle mass in a population of older T2DM patients for further analysis and early treatment. This is notably true in patients possessing high body mass index (BMI) alongside normal ASMI and HGS, potentially reducing false positive sarcopenia screening results.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov PRS: NCT03560375 . Last registration date (last update): 06/06/2018. The trial was a-priori registered before actual recruitment of subjects.</p>","PeriodicalId":520622,"journal":{"name":"European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity","volume":" ","pages":"5"},"PeriodicalIF":6.3,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39954731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}