Elizabeth M Dickson, Diogo Fp Marques, Sandra Currie, Annette Little, Kirsty Mangin, Michael Coyne, Arlene Reynolds, Jim McMenamin, David Yirrell
{"title":"The experience of point-of-care testing for influenza in Scotland in 2017/18 and 2018/19 - no gain without pain.","authors":"Elizabeth M Dickson, Diogo Fp Marques, Sandra Currie, Annette Little, Kirsty Mangin, Michael Coyne, Arlene Reynolds, Jim McMenamin, David Yirrell","doi":"10.2807/1560-7917.ES.2020.25.44.1900419","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.44.1900419","url":null,"abstract":"<p><p>BackgroundDuring the 2017/18 and 2018/19 influenza seasons, molecular amplification-based point-of-care tests (mPOCT) were introduced in Scotland to aid triaging respiratory patients for hospital admission, yet communication of results to national surveillance was unaccounted for.AimThis retrospective study aims to describe steps taken to capture mPOCT data and assess impact on influenza surveillance.MethodsQuestionnaires determined mPOCT usage in 2017/18 and 2018/19. Searches of the Electronic Communication of Surveillance in Scotland (ECOSS) database were performed and compared with information stored in laboratory information management systems. Effect of incomplete data on surveillance was determined by comparing routine against enhanced data and assessing changes in influenza activity levels determined by the moving epidemic method.ResultsThe number of areas employing mPOCT increased over the two seasons (6/14 in 2017/18 and 8/14 in 2018/19). Analysis of a small number of areas (n = 3) showed capture of positive mPOCT results in ECOSS improved between seasons and remained high (> 94%). However, capture of negative results was incomplete. Despite small discrepancies in weekly activity assessments, routine data were able to identify trend, start, peak and end of both influenza seasons.ConclusionThis study has shown an improvement in capture of data from influenza mPOCT and has highlighted issues that need to be addressed for results to be accurately captured in national surveillance. With the clear benefit to patient management we suggest careful consideration should be given to the connectivity aspects of the technology in order to ensure minimal impact on national surveillance.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38675874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorenzo Subissi, Nathalie Bossuyt, Marijke Reynders, Michèle Gérard, Nicolas Dauby, Marc Bourgeois, Bénédicte Delaere, Sophie Quoilin, Steven Van Gucht, Isabelle Thomas, Cyril Barbezange
{"title":"Capturing respiratory syncytial virus season in Belgium using the influenza severe acute respiratory infection surveillance network, season 2018/19.","authors":"Lorenzo Subissi, Nathalie Bossuyt, Marijke Reynders, Michèle Gérard, Nicolas Dauby, Marc Bourgeois, Bénédicte Delaere, Sophie Quoilin, Steven Van Gucht, Isabelle Thomas, Cyril Barbezange","doi":"10.2807/1560-7917.ES.2020.25.39.1900627","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.39.1900627","url":null,"abstract":"<p><p>BackgroundRespiratory syncytial virus (RSV) is a common cause of severe respiratory illness in young children (< 5 years old) and older adults (≥ 65 years old) leading the World Health Organization (WHO) to recommend the implementation of a dedicated surveillance in countries.AimWe tested the capacity of the severe acute respiratory infection (SARI) hospital network to contribute to RSV surveillance in Belgium.MethodsDuring the 2018/19 influenza season, we started the SARI surveillance for influenza in Belgium in week 40, earlier than in the past, to follow RSV activity, which usually precedes influenza virus circulation. While the WHO SARI case definition for influenza normally used by the SARI hospital network was employed, flexibility over the fever criterion was allowed, so patients without fever but meeting the other case definition criteria could be included in the surveillance.ResultsBetween weeks 40 2018 and 2 2019, we received 508 samples from SARI patients. We found an overall RSV detection rate of 62.4% (317/508), with rates varying depending on the age group: 77.6% in children aged < 5 years (253/326) and 34.4% in adults aged ≥ 65 years (44/128). Over 90% of the RSV-positive samples also positive for another tested respiratory virus (80/85) were from children aged < 5 years. Differences were also noted between age groups for symptoms, comorbidities and complications.ConclusionWith only marginal modifications in the case definition and the period of surveillance, the Belgian SARI network would be able to substantially contribute to RSV surveillance and burden evaluation in children and older adults, the two groups of particular interest for WHO.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38448451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ralf Dürrwald, Marianne Wedde, Barbara Biere, Djin-Ye Oh, Martina Heßler-Klee, Christian Geidel, Renate Volmer, Anja Maria Hauri, Kai Gerst, Andrea Thürmer, Sandra Appelt, Janine Reiche, Susanne Duwe, Silke Buda, Thorsten Wolff, Walter Haas
{"title":"Zoonotic infection with swine A/H1<sub>av</sub>N1 influenza virus in a child, Germany, June 2020.","authors":"Ralf Dürrwald, Marianne Wedde, Barbara Biere, Djin-Ye Oh, Martina Heßler-Klee, Christian Geidel, Renate Volmer, Anja Maria Hauri, Kai Gerst, Andrea Thürmer, Sandra Appelt, Janine Reiche, Susanne Duwe, Silke Buda, Thorsten Wolff, Walter Haas","doi":"10.2807/1560-7917.ES.2020.25.42.2001638","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.42.2001638","url":null,"abstract":"<p><p>A zoonotic A/sw/H1<sub>av</sub>N1 1C.2.2 influenza virus infection was detected in a German child that presented with influenza-like illness, including high fever. There was a history of close contact with pigs 3 days before symptom onset. The child recovered within 3 days. No other transmissions were observed. Serological investigations of the virus isolate revealed cross-reactions with ferret antisera against influenza A(H1N1)pdm09 virus, indicating a closer antigenic relationship with A(H1N1)pdm09 than with the former seasonal H1N1 viruses.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38520636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tom D Vermeulen, Johan Reimerink, Chantal Reusken, Sandra Giron, Peter J de Vries
{"title":"Autochthonous dengue in two Dutch tourists visiting Département Var, southern France, July 2020.","authors":"Tom D Vermeulen, Johan Reimerink, Chantal Reusken, Sandra Giron, Peter J de Vries","doi":"10.2807/1560-7917.ES.2020.25.39.2001670","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.39.2001670","url":null,"abstract":"<p><p>We report dengue virus (DENV) infection in two Dutch tourists who visited Département Var, southern France, in July and August 2020. As some autochthonous dengue cases have occurred in Europe in recent years, awareness among physicians and public health experts about possible intermittent presence of DENV in southern Europe is important to minimise delay in diagnosis and treatment. Quick diagnosis can lead to timely action to contain the spread of vector-borne diseases and minimise transmission.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38448453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Ziegler, Philipp Steininger, Renate Ziegler, Jörg Steinmann, Klaus Korn, Armin Ensser
{"title":"SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene.","authors":"Katharina Ziegler, Philipp Steininger, Renate Ziegler, Jörg Steinmann, Klaus Korn, Armin Ensser","doi":"10.2807/1560-7917.ES.2020.25.39.2001650","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.39.2001650","url":null,"abstract":"<p><p>We found that a single nucleotide polymorphism (SNP) in the nucleoprotein gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a patient interfered with detection in a widely used commercial assay. Some 0.2% of the isolates in the EpiCoV database contain this SNP. Although SARS-CoV-2 was still detected by the other probe in the assay, this underlines the necessity of targeting two independent essential regions of a pathogen for reliable detection.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38448449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Job vacancy at the European Centre for Disease Prevention and Control (ECDC).","authors":"","doi":"10.2807/1560-7917.ES.2020.25.42.2010221","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.42.2010221","url":null,"abstract":"","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38520631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katrin Claire Leitmeyer, Laura Espinosa, Eeva Kaarina Broberg, Marc Jean Struelens
{"title":"Automated digital reporting of clinical laboratory information to national public health surveillance systems, results of a EU/EEA survey, 2018.","authors":"Katrin Claire Leitmeyer, Laura Espinosa, Eeva Kaarina Broberg, Marc Jean Struelens","doi":"10.2807/1560-7917.ES.2020.25.39.1900591","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.39.1900591","url":null,"abstract":"<p><p>BackgroundTimely reporting of microbiology test results is essential for infection management. Automated, machine-to-machine (M2M) reporting of diagnostic and antimicrobial resistance (AMR) data from laboratory information management systems (LIMS) to public health agencies improves timeliness and completeness of communicable disease surveillance.AimWe surveyed microbiology data reporting practices for national surveillance of EU-notifiable diseases in European Union/European Economic Area (EU/EEA) countries in 2018.MethodsEuropean Centre for Disease Prevention and Control (ECDC) National Microbiology and Surveillance Focal Points completed a questionnaire on the modalities and scope of clinical microbiology laboratory data reporting.ResultsComplete data were provided for all 30 EU/EEA countries. Clinical laboratories used a LIMS in 28 countries. LIMS data on EU-notifiable diseases and AMR were M2M-reported to the national level in 14 and nine countries, respectively. In the 14 countries, associated demographic data reported allowed the de-duplication of patient reports. In 13 countries, M2M-reported data were used for cluster detection at the national level. M2M laboratory data reporting had been validated against conventional surveillance methods in six countries, and replaced those in five. Barriers to M2M reporting included lack of information technology support and financial incentives.ConclusionM2M-reported laboratory data were used for national public health surveillance and alert purposes in nearly half of the EU/EEA countries in 2018. Reported data on infectious diseases and AMR varied in extent and disease coverage across countries and laboratories. Improving automated laboratory-based surveillance will depend on financial and regulatory incentives, and harmonisation of health information and communication systems.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38448450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicola Murphy, Máirín Boland, Niamh Bambury, Margaret Fitzgerald, Liz Comerford, Niamh Dever, Margaret B O'Sullivan, Naomi Petty-Saphon, Regina Kiernan, Mette Jensen, Lois O'Connor
{"title":"A large national outbreak of COVID-19 linked to air travel, Ireland, summer 2020.","authors":"Nicola Murphy, Máirín Boland, Niamh Bambury, Margaret Fitzgerald, Liz Comerford, Niamh Dever, Margaret B O'Sullivan, Naomi Petty-Saphon, Regina Kiernan, Mette Jensen, Lois O'Connor","doi":"10.2807/1560-7917.ES.2020.25.42.2001624","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.42.2001624","url":null,"abstract":"<p><p>An outbreak of 59 cases of coronavirus disease (COVID-19) originated with 13 cases linked by a 7 h, 17% occupancy flight into Ireland, summer 2020. The flight-associated attack rate was 9.8-17.8%. Spread to 46 non-flight cases occurred country-wide. Asymptomatic/pre-symptomatic transmission in-flight from a point source is implicated by 99% homology across the virus genome in five cases travelling from three different continents. Restriction of movement on arrival and robust contact tracing can limit propagation post-flight.</p>","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38520634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resolved: Expression of concern for Euro Surveill. 2020;25(32).","authors":"","doi":"10.2807/1560-7917.ES.2020.25.39.201001en","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.39.201001en","url":null,"abstract":"","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38448452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum for Euro Surveill. 2020;25(41).","authors":"","doi":"10.2807/1560-7917.ES.2020.25.42.201022e","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2020.25.42.201022e","url":null,"abstract":"","PeriodicalId":520613,"journal":{"name":"Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin","volume":" ","pages":""},"PeriodicalIF":19.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38520633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}