Diabetes & metabolic syndrome最新文献

{"title":"Letter in response to the article \"Enhancing immunity in viral infections, with special emphasis on COVID-19: A review\" (Jayawardena et al.).","authors":"Luigi Santacroce","doi":"10.1016/j.dsx.2020.06.009","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.06.009","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"927"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.06.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38084910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence and concerns of polycystic ovary syndrome in young female university students aged 18-25 in Trinidad.","authors":"B S Nayak, Matthew Maharaj, Mitrani Maharaj, Nirvana Maharaj, Pooja Maharaj, Ravi Maharaj, Sujaya Maharaj, Vejay Maharaj, Vinay Maharaj","doi":"10.1016/j.dsx.2020.08.001","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.08.001","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"1557-1558"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38395197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to 'Vitamin D concentrations and COVID-19 infection in UK Biobank'.","authors":"Akangsha Sur Roy, Montgomery Matson, Rahul Herlekar","doi":"10.1016/j.dsx.2020.05.049","DOIUrl":"10.1016/j.dsx.2020.05.049","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"777"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38038249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on \"angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may be harmful in patients with diabetes during COVID-19 pandemic\".","authors":"Carlos M Ferrario","doi":"10.1016/j.dsx.2020.07.041","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.07.041","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"1401-1402"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.07.041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38229947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the Lysulin™ supplementation on pre-diabetes: A randomized double-blind, placebo-controlled clinical trial.","authors":"Priyanga Ranasinghe,&nbsp;Ranil Jayawardena,&nbsp;Lal Chandrasena","doi":"10.1016/j.dsx.2020.07.023","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.07.023","url":null,"abstract":"<p><strong>Background and aims: </strong>Diabetes is a leading cause of morbidity and mortality worldwide. Recent studies have demonstrated that nutraceutical products have beneficial effects in diabetes. Present study aims to investigate whether a product (Lysulin™) containing amino acid lysine, micronutrient zinc and vitamin C will have beneficial effects in pre-diabetes.</p><p><strong>Methods: </strong>A randomized, double-blind, placebo-controlled trial was conducted for a period of 6 months. The two parallel groups (1:1) were Lysulin™ (Interventional group-IG) and placebo (control group-CG). Evaluations were done at baseline, 1, 3 and 6 months. Primary outcome was defined as change in glycaemic control measured by HbA1c from baseline. Other outcomes included change in; fasting plasma glucose (FPG), 2-h OGTT plasma glucose and lipid profile from baseline. Three multiple regression analyses were performed, where change in FPG, 2-h OGTT, and HbA1c post intervention from baseline respectively were the continuous dependent variable with other independent variables.</p><p><strong>Results: </strong>One hundred and ten participants were recruited, 50% (n = 55) were males and mean age (±SD) was 46.7 ± 9.9 years. A significantly higher percentage of participants in CG (25.4%, n = 14) developed diabetes in comparison to IG (7.3%, n = 4) (p = 0.018). FPG, 2-h OGTT and HbA1c significantly reduced in the IG only. Both total cholesterol and LDL cholesterol decreased significantly from baseline only in the IG. In all three regression models the best predictor of respective dependent variable was Lysulin™ treatment.</p><p><strong>Conclusions: </strong>Lysulin™ improved glycaemic control, with reduced progression to diabetes, in those with pre-diabetes. Treatment also showed a beneficial reduction in total and LDL cholesterol levels.</p><p><strong>Trial registration: </strong>Sri Lanka Clinical Trials Registry, identifier: SLCTR/2018/022 (http://slctr.lk/trials/1290). Registered on 13th July 2018; Study protocol version 2.0 (23rd March 2018).</p>","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"1479-1486"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.07.023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38273588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to \"Letter to editor in response to \"COVID-19: From bench to bedside\" by Singh A et al.\" [Diabetes & Metab Syndrome: Clin Res Rev 14 (5) (2020) 815-816 of duplicate article].","authors":"Harpreet Singh,&nbsp;Deba Prasad Dhibar","doi":"10.1016/j.dsx.2020.07.009","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.07.009","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"1597"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.07.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38386283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of metabolic syndrome in patients living with HIV/AIDS receiving care at referral hospitals of Northwest Ethiopia: A hospital-based cross-sectional study, 2019.","authors":"Alemu Gebrie","doi":"10.1016/j.dsx.2020.08.002","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.08.002","url":null,"abstract":"<p><strong>Introduction: </strong>There is a growing concern about metabolic syndrome among HIV-infected patients. Therefore, this study aims to determine the burden of metabolic syndrome among patients living with HIV/AIDS at referral hospitals of Northwest Ethiopia.</p><p><strong>Materials and methods: </strong>a hospital-based cross-sectional study was conducted at referral hospitals of Northwest Ethiopia between February 2019 and April 2019. Using the WHO stepwise approach, sociodemographic, behavioral, and clinical data were collected from 407 adult patients. Lipid profiles, fasting blood sugar, as well as anthropometric indicators, were also measured. In addition, multivariate binary logistic regression analysis was performed.</p><p><strong>Results: </strong>The prevalence of metabolic syndrome was found to be 24.6% (95 CI: 20.42,28.78). Multivariate logistic regression analysis revealed that age [AOR (95% CI) 1.04 (1.003,1.074), p < 0.05]; female gender [AOR (95% CI) 9.66 (4.40, 21.22), p < 0.05]; marital status, single referent, separated [AOR (95% CI) 4.77 (1.83, 12.41), p < 0.05] and widowed [AOR (95% CI) 3.868(1.375, 10.883), p < 0.05]; monthly income (<2000 Ethiopian Birr referent) > 5000 ETB [AOR (95% CI) 3.543 (1.299, 9.664), p < 0.05]; and urban residence [AOR (95% CI) 2.118 (1.089, 4.119), p < 0.05] have shown statistically significant association with odds of metabolic syndrome.</p><p><strong>Conclusion: </strong>The burden of metabolic syndrome was notably higher. Age, gender, marital status, monthly income, residence, waist circumference, and hypertension of patients were significantly associated with metabolic syndrome.</p>","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"1551-1556"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38395195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter in response to the article: Comorbidities in COVID-19: Outcomes in hypertensive cohort and controversies with renin angiotensin system blockers (Singh et al.).","authors":"Kunal Mahajan,&nbsp;Naresh Gaur","doi":"10.1016/j.dsx.2020.05.029","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.05.029","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"723-724"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.05.029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37989424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the letter of L. Santacroce regarding article \"Enhancing immunity in viral infections, with special emphasis on COVID-19: A review\" (Jayawardena et al.).","authors":"Ranil Jayawardena,&nbsp;Piumika Sooriyaarachchi,&nbsp;Michael Chourdakis,&nbsp;Chandima Jeewandara,&nbsp;Priyanga Ranasinghe","doi":"10.1016/j.dsx.2020.06.017","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.06.017","url":null,"abstract":"","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"839"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.06.017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38051318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Established and novel gender dimorphisms in type 2 diabetes mellitus: Insights from a multiethnic cohort.","authors":"Michel P Hermans,&nbsp;Sylvie A Ahn,&nbsp;Shaukat Sadikot,&nbsp;Michel F Rousseau","doi":"10.1016/j.dsx.2020.07.027","DOIUrl":"https://doi.org/10.1016/j.dsx.2020.07.027","url":null,"abstract":"<p><strong>Background and aims: </strong>In type 2 diabetes mellitus (T2DM), sexual dimorphisms modulate the natural histories of hyperglycemia, anthropophysical/cardiometabolic phenotype, and susceptibility to chronic micro and macrovascular complications. The purpose of this work was to revisit known or new dimorphisms within a multiethnic cohort.</p><p><strong>Methods: </strong>Among 1238 T2DM patients, men (63%) were compared to women (37%), including leading ethnicities: Whites (67.4%; 542 men; 293 women); Maghrebians (9.4%; 62 men; 54 women); and Blacks (12.5%; 92 men; 63 women).</p><p><strong>Results: </strong>Age, BMI, diabetes duration, insulin sensitivity, B-cell function loss, HbA1c, and hyperglycemia index were similar in both genders. All-cause microangiopathy and cerebrovascular disease did not differ between sexes. Women had significantly more retinopathy (27% vs. 21%) and men more microalbuminuria (25% vs. 19%), all-cause macroangiopathy (40% vs. 26%), CAD (29% vs. 17%) and PAD (11% vs. 6%). Among Blacks, sexual dimorphism in terms of retinopathy was more pronounced (24% in women vs. 11%), while there was no sexual dimorphism in all-cause macroangiopathy, CAD or PAD. B-cell function loss was faster among North African men (+15%), who also had more hepatic steatosis (+27%) than women.</p><p><strong>Conclusions: </strong>T2DM abolishes the CV protection provided by the female gender in Blacks. In White women, the loss of CV protection in diabetes is limited to cerebrovascular disease. In Black women, a markedly increased risk of retinopathy is present, despite glycemic exposure similat to men. Sexual dimorphisms do not affect glucose homeostasis and metabolic control in all ethnicities, except for lesser B-cell function loss in Maghrebian women.</p>","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"1503-1509"},"PeriodicalIF":10.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2020.07.027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38273043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}