Colombia medica (Cali, Colombia)最新文献

{"title":"Microsurgical technique for reconstruction of Hemi-uterus with non-communicating rudimentary uterine horns.","authors":"Enrique Herrera Castañeda,&nbsp;William Andrés Piñeros Castillo,&nbsp;Marlly Paola Paredes Soto","doi":"10.25100/cm.v53i2.4855","DOIUrl":"https://doi.org/10.25100/cm.v53i2.4855","url":null,"abstract":"<p><strong>Case description: </strong>Three cases of patients diagnosed with Hemi-uterus with non-communicating functional rudimentary cavity are reported.</p><p><strong>Clinical findings: </strong>Adolescent patients with the presence of disabling pelvic pain during menstrual periods, in addition to depressive states and functional disability secondary to pain.</p><p><strong>Treatment and outcome: </strong>Reconstruction of Hemi-uterus with non-communicating functional rudimentary cavity using a microsurgical technique, without the need for non-communicating horn resection. The patients were assessed at the 1st, third, and sixth months, showing a marked improvement in their dysmenorrhea. In addition, there was an improvement in the depressive state; there was no change in the volume of her menstrual bleeding, and one of these patients achieved pregnancy with normal prenatal control and cesarean delivery, obtaining a full-term newborn without complications.</p><p><strong>Clinical relevance: </strong>Description of a novel microsurgical technique for the management of the hemi-uterus with a non-communicating functional rudimentary cavity, which could benefit not only the reduction of associated symptoms but could also become an alternative to improve fertility in these patients.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e5004855"},"PeriodicalIF":1.1,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/c5/1657-9534-cm-53-02-e5004855.PMC9651172.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40481925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Triphasic waves and brain atrophy in patients with acute encephalopathy.","authors":"Xavier Merchán Del Hierro,&nbsp;Gabriel Persi,&nbsp;Galeno Rojas,&nbsp;Emilia Gatto,&nbsp;Nahuel Pereira de Silva","doi":"10.25100/cm.v53i2.4500","DOIUrl":"https://doi.org/10.25100/cm.v53i2.4500","url":null,"abstract":"<p><strong>Introduction: </strong>Triphasic waves (TW) constitute an electroencephalographic pattern associated with certain kinds of encephalopathy. Brain atrophy may be a predisposing factor linked with TW.</p><p><strong>Objective: </strong>To compare the degree of brain atrophy and white matter disease between patients with acute encephalopathy with and without TW.</p><p><strong>Methods: </strong>A retrospective observational study including adult patients with encephalopathy, with and without TW, hospitalized between 2016 and 2017. The degree of brain atrophy and white matter lesion were defined using the Global Cortical Atrophy and Age Related White Matter Changes (ARWMC) scales, respectively. Scores were compared between groups. Mortality rates were registered.</p><p><strong>Results: </strong>Sixteen patients with TW were identified matched by age and sex with 30 patients without TW. The mean age was 80 years in the TW group. Women represented 87.5%. Multifactorial encephalopathy was the most frequent diagnosis followed by metabolic encephalopathy. Patients with TW had more brain atrophy (10.43 vs 6.9, <i>p</i>= 0.03). Mean ARWMC was 9.43±6.5 and 8.5 ±7.89 in patients with and without TW respectively (<i>p</i>= 0.5). Mortality rate was higher in the TW group (31.25 vs 6.66% <i>p</i>= 0.02).</p><p><strong>Conclusions: </strong>Patients with acute encephalopathy and TW had higher degree of cerebral atrophy. It is possible that this structural alteration predisposes to the appearance of TW. There was no significant difference in white matter lesion degree. The mortality of the TW group was high, so future studies are necessary to determine their prognostic value.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2034500"},"PeriodicalIF":1.1,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/2b/1657-9534-cm-53-02-e2034500.PMC9651166.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40481926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary identification of pathogenic variants in an Afro-Colombian Raizal family with risk factors for glaucoma.","authors":"Harry Castillo-Plata,&nbsp;Nelson Rivera-Franco,&nbsp;Claudia Valencia-Peña,&nbsp;Wilmar Saldarriaga-Gil,&nbsp;Lyle Newball,&nbsp;Andres Castillo","doi":"10.25100/cm.v53i2.5107","DOIUrl":"https://doi.org/10.25100/cm.v53i2.5107","url":null,"abstract":"<p><strong>Objective: </strong>To identify pathogenic variants in an Afro-Colombian <i>Raizal</i> family with risk factors for glaucoma.</p><p><strong>Methods: </strong>In the present study, whole exome sequencing was performed on seven members of a Raizal family from the archipelago of San Andrés, Providencia, and Santa Catalina, in the Caribbean region of Colombia. Four of them had been diagnosed with glaucoma. In addition, two healthy volunteers from the island were included.</p><p><strong>Results: </strong>Of the 198 single nucleotide variants associated with glaucoma, previously reported by the DisGeNET database, four were identified in members of the Raizal family: rs11938093, rs7336216, rs3817672, and rs983034. Furthermore, single nucleotide variant rs983034 was identified in the Wnt ligand secretion mediator gene in all members of the family but not in healthy volunteers. Notably, WLS dysfunctions have been linked to pathology in the trabecular meshwork of the eye. Trabecular meshwork is an important regulator of the outflow of aqueous humor that maintains intraocular pressure (intraocular pressure) at normal levels. Damage to trabecular meshwork is associated with ocular hypertension, which leads to glaucoma progression. In relation to the other single nucleotide variants that were identified, their presence was confirmed in some members of the Raizal family. However, it is still unclear the pathophysiological cause that associates these single nucleotide variants with glaucoma.</p><p><strong>Conclusions: </strong>It was possible to identify four non-synonymous single nucleotide variants that predict significant damage to the structure and function of genes associated with glaucoma pathology in an Afro-Colombian.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2065107"},"PeriodicalIF":1.1,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/77/3f/1657-9534-cm-53-02-e2065107.PMC9651171.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40481923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction analysis of <i>FTO</i> and <i>IRX3</i> genes with obesity and related metabolic disorders in an admixed Latin American population: a possible risk increases of body weight excess.","authors":"María Stephany Ruiz-Díaz,&nbsp;Diana Mena-Yi,&nbsp;Doris Gómez-Camargo,&nbsp;Gustavo Mora-García","doi":"10.25100/cm.v53i2.4874","DOIUrl":"https://doi.org/10.25100/cm.v53i2.4874","url":null,"abstract":"<p><strong>Background: </strong>Fat Mass and Obesity-related <i>(FTO)</i> has been one of the genes consistently related to common obesity. Single nucleotide polymorphisms (SNPs) in <i>FTO</i> have been linked with the <i>IRX3</i> gene.</p><p><strong>Aim: </strong>This study was designed by testing the hypothesis that: i) common SNPs in <i>FTO</i> and <i>IRX3</i> are associated with obesity and related disorders; ii) there is significant linkage disequilibrium between both genes.</p><p><strong>Methods: </strong>A cross-sectional study was carried out on the Colombian Caribbean Coast. Anthropometric and biochemical variables were measured, and obesity and metabolic disorders were diagnosed. Four SNPs were genotyped: 3 at <i>FTO</i> locus (rs17817449, rs8050136, rs9939609) and one at <i>IRX3</i> locus (rs3751723). LD between these SNPs was estimated. A logistic regression model was applied to estimate associations.</p><p><strong>Results: </strong>A total of 792 subjects were included. <i>FTO</i> and <i>IRX3</i> were not in LD (D'≤ 0.03; R²≤ 0.03). TT genotype (rs9939609) was found to be associated with waist circumference (<i>p</i>= 0.04; adj-<i>p</i>= 0.01), and <i>IRX3</i> SNP with Body Weight Excess (BWE) (OR= 1.06, adj-<i>p</i>= 0.03). One <i>FTO-IRX3</i> haplotype was associated with BWE (G-A-A-T, rs17817449-rs8050136-rs9939609-rs3751723; OR= 0.67, <i>p</i>= 0.04). The statistical significance of these relations continued after admixture adjustment for a three-hybrid population (<i>p</i>= 0.03).</p><p><strong>Conclusions: </strong><i>FTO</i> was related to waist circumference, and <i>IRX3</i> was associated with BWE in Latin American adults. This relation remained statistically significant after an adjustment for sex, age, and genetic ancestry was performed. Despite that these genes were not in LD, findings of a haplotype involving <i>FTO-IRX3</i> suggest a gene-gene interaction associated with an increased risk of BWE.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2044874"},"PeriodicalIF":1.1,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/be/85/1657-9534-cm-53-02-e2044874.PMC9651168.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40482734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibody deficiencies with normal IgG in adults with Non-cystic fibrosis bronchiectasis or recurrent pneumonia: Cross-sectional study.","authors":"Andres F Zea-Vera,&nbsp;Mario Alejandro Chacón,&nbsp;Beatriz Parra","doi":"10.25100/cm.v53i2.4832","DOIUrl":"https://doi.org/10.25100/cm.v53i2.4832","url":null,"abstract":"Abstract Background: Inborn errors of immunity, mainly Predominantly Antibody deficiencies with normal IgG levels are unrecognized in adults with lung diseases such as bronchiectasis or recurrent pneumonia. Objective: To determine IgM, IgA, IgG2 subclass deficiencies, and Specific antibody deficiency (anti-pneumococcal polysaccharide antibodies) in adults with non-cystic fibrosis bronchiectasis or recurrent pneumonia. Methods: Cross-sectional study. Consecutive patients with non-cystic fibrosis bronchiectasis or recurrent pneumonia were recruited in Cali, Colombia. IgG, IgA, IgM, and IgE, IgG2subclass and IgG anti-pneumococcal serum levels were measured. Results: Among the 110 participants enrolled, Antibody deficiencies with normal serum IgG levels were found in 11(10%) cases. IgA deficiency (3 cases), IgM deficiency (2 cases) and IgG2 deficiency (2 cases) were the most frequent primary immunodeficiencies. In addition, IgG2+IgA deficiency, Ataxia-telangiectasia, Hyper-IgE syndrome and Specific Antibody Deficiency(anti-polysaccharides) were found in one case each. Conclusions: Predominantly antibody deficiencies with normal IgG levels are an important etiology of non-cystic fibrosis bronchiectasis and recurrent pneumonia in adults.","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2014832"},"PeriodicalIF":1.1,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/08/1657-9534-cm-53-02-e2014832.PMC9651167.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40506842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and associated factors for asthma in adults in Quito: a cross-sectional study.","authors":"Angelita Cabrera,&nbsp;César Picado,&nbsp;Sergio Barba,&nbsp;Oscar Fonseca,&nbsp;Eduardo Castro,&nbsp;Luis García-Marcos,&nbsp;Alejandro Rodríguez","doi":"10.25100/cm.v53i2.5086","DOIUrl":"https://doi.org/10.25100/cm.v53i2.5086","url":null,"abstract":"<p><strong>Background: </strong>Although several epidemiological studies of asthma have been carried out in Ecuador in the last two decades, none of these has estimated the prevalence of asthma in adult populations.</p><p><strong>Objective: </strong>To estimate the prevalence of asthma symptoms in adults in the city of Quito and to identify possible associated factors.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on subjects older than 18 years residing in the Metropolitan District of Quito. The Global Asthma Network (GAN) questionnaire was applied to collect information on asthma symptoms and sociodemographic and lifestyle data. Bivariate and multivariate analyses with logistic regression were used to identify asthma-related factors.</p><p><strong>Results: </strong>2,476 subjects answered the questionnaire (80.9% women, mean age 40 years). The prevalence of wheezing in the last 12 months, asthma ever, and asthma diagnosed by a doctor were 6.3%, 1.9% and 1.6%, respectively. The prevalence of rhinitis ever and eczema ever was 13.7% and 5.5%. The presence of mould at home (OR: 2.13; 95% CI: 1.48 -3.06; <i>p</i> <0.001), cat at home (OR: 1.06; 95% CI: 1.06 -2.13; <i>p</i> <0.022) and rhinitis at some time (OR: 3.65; 95% CI: 2.53 - 5.29; <i>p</i> <0.022) were associated with the presence of wheezing in the last 12 months.</p><p><strong>Conclusions: </strong>Our study shows that, compared to other cities in Latin America, the prevalence of asthma in adults in Quito is relatively low. Along with the presence of rhinitis, factors related to housing quality are closely linked to the occurrence of asthma in adult populations.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2025086"},"PeriodicalIF":1.1,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/12/1657-9534-cm-53-02-e2025086.PMC9651165.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40479893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Religiosity, physical and functional health in older people in Chile.","authors":"M Beatriz Fernández Lorca","doi":"10.25100/cm.v53i2.4846","DOIUrl":"https://doi.org/10.25100/cm.v53i2.4846","url":null,"abstract":"<p><strong>Objective: </strong>To establish the association between different dimensions of religiosity - organizational, non-organizational and intrinsic - and physical and functional health indicators in older people in Chile.</p><p><strong>Methods: </strong>Data from the Fifth Survey on Quality of Life in Old Age 2019 were used. Descriptive and explanatory analyses were performed using logistic, linear and multinomial regression models, with dependent variables being self-perception of health, functional dependence, number of chronic diseases and perception of health compared with other people of the same age. As predictors, indicators of the three dimensions of religiosity (DUREL Scale) were included, controlling for the MOS-SS Social Support Scale, Apgar Family Functioning Scale, educational level, gender, age, and living with a partner.</p><p><strong>Results: </strong>Almost a third of older Chileans attend religious services frequently, and half of them pray frequently. On a range of 1 to 5, the mean intrinsic religiosity is 3.94. 46% perceive their health to be good/very good and about half perceive their health as better than their peers. On 0 to 5, the mean number of chronic diseases is 1.69. 6% are classified as functionally dependent. The only significant relationship observed was between religious attendance and a lower probability of presenting functional dependency; on the other hand, praying increases such probabilities and a relationship between attendance and a better perception of health compared with other people of the same age.</p><p><strong>Conclusion: </strong>Organisational religiosity is a psychosocial resource that is positively associated with the process of successful aging.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2004846"},"PeriodicalIF":1.1,"publicationDate":"2022-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a6/19/1657-9534-cm-53-02-e2004846.PMC9651164.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40479892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of the COVID-19 pandemic on the oncology services demand in a middle-income setting with universal health insurance.","authors":"María Zuluaga Patiño,&nbsp;María Camila Luna Benitez,&nbsp;Natalie Jurado Sanabria,&nbsp;Beatriz Soto-Cala,&nbsp;Julio Cesar Solano Vega,&nbsp;Ricardo Antonio Sánchez Forero,&nbsp;Raúl Murillo","doi":"10.25100/cm.v53i1.5115","DOIUrl":"https://doi.org/10.25100/cm.v53i1.5115","url":null,"abstract":"<p><strong>Aim: </strong>We analyze the impact of the COVID-19 pandemic on oncology service demand in a middle-income country with universal health coverage.</p><p><strong>Methods: </strong>We collected data from January 1^st-2017 to December 31^th-2021 at a reference center in Bogotá-Colombia regarding first-time consultations of cross-cutting services (clinical oncology, hematology, palliative care, radiation oncology); specialized multidisciplinary units (breast, prostate, lung, stomach); inpatient and outpatient systemic therapy; radiotherapy; oncology surgery; and bone marrow transplant. A descriptive time series analysis was performed, estimating monthly percent change and endemic channels.</p><p><strong>Results: </strong>Starting the confinement (April 2020), a general decrease in service demand was observed (R: -14.9% to -90.0%), with an additional but lower decrease in August 2020 coinciding with the first pandemic wave (R: -11.3% to -70.0%). Follow-up visits and ambulatory treatment showed no consistent reductions. New patients' consultations for cross-cutting services had a speedy recovery (1 month), but clinical oncology, specialized units, and in-hospital treatment resumed more slowly. Only breast and stomach cancer showed a sustained reduction in early-stage disease. Women and older patients had a more significant reductionin service demand. Conclusion: Despite no changes in service supply, the confinement induced a significant reduction in service demand. Variations by cancer type, service type, and population demographics deserve careful consideration for a suitable response to the emergency. The speedy recovery and the absence of a significant decrease during subsequent waves of the pandemic suggest patient resiliency and a lower impact than expected in middle-income settings in the presence of universal health insurance.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2065115"},"PeriodicalIF":1.1,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/f8/1657-9534-cm-53-01-e2065115.PMC9651084.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40720677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in cancer incidence and mortality in Manizales, Colombia, 2008-2017.","authors":"Nelson Arias-Ortiz,&nbsp;Juan David Rodríguez-Betancourt","doi":"10.25100/cm.v53i1.4920","DOIUrl":"https://doi.org/10.25100/cm.v53i1.4920","url":null,"abstract":"<p><strong>Objective: </strong>To describe cancer incidence and mortality trends in Manizales, Colombia, between 2008-2017.</p><p><strong>Methods: </strong>All incident cancer cases in Manizales collected by the Population-based Manizales Cancer Registry between January 1, 2008, and December 31, 2017, and all deaths caused by cancer in the same period, were included. The population at risk was obtained from the National Administrative Department of Statistics databases. Age-standardized incidence and mortality rates were calculated by sex and cancer site. Changes in trends were assessed using Joinpoint regression.</p><p><strong>Results: </strong>There were 11,188 incident cases, 56.7% in women. There were 4,996 cancer deaths, 52.6% in women. Breast, prostate, stomach, thyroid, lung, and colon cancers accounted for 50% of all incident cases. During this period, the incidence in women decreased and equaled that of men due to a significant decrease in cervical, stomach, and lung cancers, among others; likewise, mortality in women decreased slightly due to the reduction in deaths from cervical, stomach, esophagus, and connective tissue cancers. In contrast, in men, overall incidence and mortality remained unchanged.</p><p><strong>Conclusions: </strong>In Manizales, population aging has contributed to an increased burden of cancer. In terms of incidence and mortality, progress in the fight against this disease is still discrete. It is a priority to reinforce cancer control strategies with a differential approach by sex.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2044920"},"PeriodicalIF":1.1,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/4e/1657-9534-cm-53-01-e2044920.PMC9651083.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40702258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age, period and cohort effects on mortality from cervical cancer in Colombia between 1985 and 2014.","authors":"Lina Angélica Buitrago Reyes,&nbsp;Oscar Andrés Gamboa Garay,&nbsp;Jairo Alonso Hernández","doi":"10.25100/cm.v53i1.4873","DOIUrl":"https://doi.org/10.25100/cm.v53i1.4873","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the cervix cancer mortality in Colombia, based on age, period and cohort effects.</p><p><strong>Methods: </strong>The mortality and population data were taken from the official databases of the National Administrative Department of Statistics, DANE. Five models were adjusted, the significance of the effects was obtained by comparing them through the likelihood ratio test.</p><p><strong>Results: </strong>The age-adjusted mortality rate, in deaths was 15.09/100,000 woman, at 1985-1989 period, and 10.21 at 2010-2014 period. The annual percentage average change was -1.45% (95% CI: -1.57% to -1.34%). Age, period and cohort effects were found.</p><p><strong>Conclusions: </strong>Demographic factors could explain the behavior of cervical cancer mortality in Colombia, as well as the establishment of public health measures in the last two decades.</p>","PeriodicalId":520596,"journal":{"name":"Colombia medica (Cali, Colombia)","volume":" ","pages":"e2074873"},"PeriodicalIF":1.1,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/3b/1657-9534-cm-53-01-e2074873.PMC9673748.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40712921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}