Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery最新文献

{"title":"Diffuse hemispheric glioma, H3 G34-mutant, in Simpson-Golabi-Behmel syndrome: the first reported case.","authors":"Hidefumi Amisaki, Atsushi Kambe, Hiroki Yoshioka, Yuichiro Nagao, Sadaharu Tabuchi, Masamichi Kurosaki","doi":"10.1007/s00381-026-07417-3","DOIUrl":"10.1007/s00381-026-07417-3","url":null,"abstract":"<p><p>Simpson-Golabi-Behmel syndrome (SGBS) is an overgrowth syndrome associated with an increased risk of certain malignancies; however, gliomas have not previously been reported in patients with SGBS. Loss-of-function variants in glypican-3 (GPC3) represent the primary molecular mechanism underlying SGBS-related overgrowth and tumorigenesis, although their relationship with gliomas remains unclear. We report a case of an 18-year-old male who had been clinically diagnosed with Sotos syndrome in childhood. He presented with sudden impaired consciousness, and neuroimaging revealed a large tumor in the left occipitoparietal lobe, which was subsequently resected. Histopathological analysis demonstrated a pediatric-type diffuse hemispheric glioma, H3 G34-mutant (CNS WHO grade 4). Next-generation sequencing of peripheral blood DNA identified a germline hemizygous deletion encompassing exons 3-5 of GPC3, leading to a revised diagnosis of SGBS. To our knowledge, this is the first reported case of SGBS associated with a glioma. This case raises the possibility that GPC3 alterations may contribute to gliomagenesis, including in H3 G34-mutant diffuse hemispheric glioma.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148612074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment and outcomes of neural tube defects at the university of Gondar Comprehensive Specialized Hospital, Ethiopia: a two-year retrospective review.","authors":"Eyob Ayenew Engidaw, Esayas Adefris Tefera, Kenean Mesfin Bekele, Eyosias Mesfin Belayneh, Cheru Lilay Gebrehiwet, Yohannis Derebew Molla","doi":"10.1007/s00381-026-07411-9","DOIUrl":"10.1007/s00381-026-07411-9","url":null,"abstract":"<p><strong>Introduction: </strong>Spina bifida, particularly myelomeningocele (MMC), is one of the most common congenital central nervous system abnormalities compatible with life. Despite global efforts to reduce its incidence through folic acid fortification, the burden remains high in low-resource settings like Ethiopia. This study aimed to analyze the pattern of presentation, clinical characteristics, management, and outcomes of spina bifida spectrum disorders (SBSDs) at the University of Gondar Comprehensive Specialized Hospital.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted on 240 neonates and infants with neural tube defects, of whom 176 had confirmed spina bifida spectrum disorders (SBSDs) treated between December 2022 and November 2024 G.C at the University of Gondar Comprehensive Specialized Hospital. Data were extracted from medical records, including demographics, lesion characteristics, associated anomalies, surgical interventions, complications, and discharge outcomes. Descriptive statistics were used for analysis via SPSS version 27.</p><p><strong>Result: </strong>Among the 176 confirmed SBSD cases (out of the total 240 patients), myelomeningocele was the most prevalent diagnosis, accounting for 77.8% of cases, followed by encephalocele (10.7%) and meningocele (7.9%). The most common lesion locations were lumbosacral (39.4%), lumbar (28.1%), and thoracolumbar (19.4%). Hydrocephalus was present in 78.3% of the total cohort and 71% of SBSD cases, with (66.4%) of those directly associated with SBSD, while sonographic Chiari malformation was identified in (31.3%). Prenatal diagnosis was made only in 10 (4.2%) patients and no counselling or intervention was employed. A total of 260 surgeries were performed for the cases, with the most common being neural tube defect repair/closure (58.5%), and followed by ventriculoperitoneal (VP) shunt insertion (25.0%). Endoscopic third ventriculostomy was done for (5.4%) of cases. Postoperative complications occurred in a considerable proportion of patients (33.8%), although most were minor and manageable, including wound infections (4.2%), seizures (5.0%), shunt malfunctions (0.4%), and mortality rate was (4.6%). Only 109 patients (45.4%) received physical rehabilitation, and developmental delays were noted in 107 (44.6%) cases. School attendance data were undocumented in (78.8%) of patients.</p><p><strong>Conclusion: </strong>The study highlights the higher prevalence of severe SBSDs in northwest Ethiopia, with significant associated morbidity. While surgical management addressed immediate needs, comprehensive care remained deficient. Major gaps persist in prenatal prevention, multidisciplinary follow-up, and rehabilitation. Enhancing public health strategies-including folic acid supplementation, early diagnosis, and integrated care-is essential to improve the overall outcomes.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148595419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pericardial migration of ventriculoperitoneal shunt: a case report with review of the literature.","authors":"Yehia Nabil, Amr AlBakry, Mohammed Elbanna, Ahmed G ElToukhy, Ayman H Fouda, Mahmoud M Taha","doi":"10.1007/s00381-026-07407-5","DOIUrl":"10.1007/s00381-026-07407-5","url":null,"abstract":"<p><strong>Background: </strong>Ventriculoperitoneal (VP) shunting is the standard surgical treatment for hydrocephalus, yet it is associated with a wide range of complications. Distal catheter migration into the pericardial cavity is exceedingly rare and poses an immediate life-threatening risk due to potential cardiac tamponade.</p><p><strong>Case presentation: </strong>A 1-year-old male infant, who had undergone VP shunt insertion for congenital communicating hydrocephalus at 3 months of age, presented with acute respiratory distress. Neuroimaging revealed a right-sided subdural hygroma. Chest imaging demonstrated a right pleural effusion and a large pericardial effusion, with the distal tip of the VP shunt catheter visualized within the pericardial sac. Urgent multidisciplinary intervention involving neurosurgery, pediatric surgery, and cardiothoracic surgery was undertaken. The migrated catheter was removed; the pericardial defect was repaired, and a new distal catheter was repositioned into the peritoneal cavity. Temporary ligation of the shunt was performed to manage the subdural hygroma, followed by gradual reopening after clinical and radiological resolution.</p><p><strong>Conclusion: </strong>Pericardial migration of a VP shunt is a rare but potentially fatal complication. Early recognition through appropriate imaging and prompt multidisciplinary surgical management are crucial to achieving favorable outcomes and preventing mortality.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148595483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical significance of flow void absence following endoscopic third ventriculostomy in asymptomatic patients: an ISPN-IFNE Survey.","authors":"Jonathan Roth, Shlomi Constantini, Jehuda Soleman","doi":"10.1007/s00381-026-07406-6","DOIUrl":"10.1007/s00381-026-07406-6","url":null,"abstract":"<p><strong>Introduction: </strong>Endoscopic third ventriculostomy (ETV) is an established treatment for obstructive hydrocephalus. Nevertheless, life-threatening late failure may occur. MRI-based assessment of stoma patency, particularly via flow void visualization, is widely used during the follow-up period. However, the clinical and practical significance of an absent flow void in asymptomatic patients remains unclear.</p><p><strong>Methods: </strong>An international survey was developed by the International Society of Pediatric Neurosurgery (ISPN) and International Federation of NeuroEndoscopy (IFNE) and distributed to neurosurgeons between May and December 2025. The survey addressed diagnostic interpretation and management of flow void findings following ETV, including scenarios of absent or disappearing flow voids. Responses were descriptive and analyzed accordingly.</p><p><strong>Results: </strong>A total of 83 respondents participated. Most (78%) routinely perform postoperative MRI, predominantly using sagittal T2-weighted sequences. Fifty-nine percent considered the presence of a flow void indicative of ETV function. 74.6% regarded absent flow void as the imaging finding most associated with failure. Thirty-six percent interpreted absence of flow void on initial imaging as failure, increasing to 53% when a previously present flow void disappeared. Despite this, the majority favored continued clinical and radiological follow-up rather than intervention for asymptomatic patients. Notably, many respondents reported asymptomatic patients without flow void who later developed clinical failure.</p><p><strong>Conclusions: </strong>Management of absent flow void after ETV is heterogeneous. While flow void was perceived as an important marker, its absence alone did not mandate intervention according to most respondents. There is a need for standardized guidelines and further studies to identify reliable predictors of late ETV failure.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148595475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perhaps we are asking the wrong question: should we predict permanent shunt dependency or understand why it develops?","authors":"Demet Evleksiz, Gardashkhan Karımzada","doi":"10.1007/s00381-026-07412-8","DOIUrl":"10.1007/s00381-026-07412-8","url":null,"abstract":"","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148581944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric mortality from neurofibromatosis and malignant peripheral nerve sheath tumors in Brazil, 2008-2023: a 16-year nationwide analysis of persistent disparities.","authors":"Karina Munhoz de Paula Alves Coelho, José Guilherme Pickler, José Cândido Caldeira Xavier-Júnior, Francis Rossetti Pedack, Raquel Francine Liermann Garcia, Carlos Frederico Fronza, Bruna Louise Silva, Acir Alves Coelho Junior, Paulo Henrique Condeixa de França, Bárbara Sarni Sanches, Priscila Ferraz Franczak, Gustavo Rassier Isolan, Marcelo Gerardin Poirot Land, Rafael Roesler","doi":"10.1007/s00381-026-07415-5","DOIUrl":"10.1007/s00381-026-07415-5","url":null,"abstract":"<p><strong>Purpose: </strong>Neurofibromatosis (NF) comprises genetic tumor predisposition syndromes with multisystem involvement, yet pediatric mortality data remain scarce in middle-income settings. Malignant peripheral nerve sheath tumors (MPNST) represent the leading cause of premature death in this population. This study analyzed 16-year temporal trends and regional disparities in pediatric NF/MPNST mortality and hospitalizations in Brazil.</p><p><strong>Methods: </strong>We conducted a nationwide ecological study of individuals aged 0-19 years from 2008 to 2023. Mortality data were obtained from the Mortality Information System (SIM) and hospital admissions from the Hospital Information System (SIH/SUS), with temporal trends assessed using Prais-Winsten regression. We calculated Age-Specific Mortality Rates (ASMRs) and assessed excess mortality risk using Standardized Mortality Ratios (SMR) to identify regional disparities.</p><p><strong>Results: </strong>A total of 177 pediatric deaths were identified, with MPNST accounting for 64.9% (N = 115) and NF for 35.1% (N = 62). SMR analysis revealed significant geographic inequalities. Children aged 0-9 in the South region faced a mortality risk double that of the reference population (SMR = 2.02; 95% CI 1.08-3.46; p = 0.010), whereas adolescents in the North region exhibited significantly lower-than-expected mortality. Despite global therapeutic advances, mortality rates in Brazil remained statistically stagnant across all age groups and conditions (p values were non-significant). Conversely, NF-related hospitalizations demonstrated an increasing trend (+ 2.98% annually for ages 0-9; + 1.94% for ages 10-19), while MPNST admissions remained stable.</p><p><strong>Conclusion: </strong>Pediatric mortality from NF and MPNST in Brazil has remained unchanged for 16 years, contrasting with the rising trend in NF-related hospitalizations. This discrepancy, coupled with marked regional disparities, suggests persistent structural challenges in early diagnosis and equitable access to specialized oncology care. These findings highlight a critical need for national notification systems and improved therapeutic strategies for affected children and adolescents.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148581947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using rapid-sequence MRI scans to compare ventricular and intracranial volumes in shunted and non-shunted children with myelomeningocele: a retrospective observational cohort study.","authors":"Maya Parker, Oumou Kalsoum Mbacke, Divine Nwafor, Abhishek Kumar, Xue Feng, Ryan Kellogg, David Martin, Amanda Hendrix, Heather Spader","doi":"10.1007/s00381-026-07410-w","DOIUrl":"10.1007/s00381-026-07410-w","url":null,"abstract":"<p><strong>Purpose: </strong>Hydrocephalus is a common complication of myelomeningocele (MMC), typically managed with a ventriculoperitoneal shunt (VPS). Despite clinical relevance, there remains a paucity of studies quantitatively comparing intracranial and ventricular volumes in shunted versus non-shunted MMC patients. This study aims to determine whether significant volumetric differences exist between these groups.</p><p><strong>Methods: </strong>Ninety-one MRIs from 19 MMC patients (13 shunted, 6 non-shunted), aged 0-3 years, were retrospectively analyzed. Volumes were obtained from rapid-sequence MRIs using automatic segmentation with manual correction. Outcomes included ventricular volume, intracranial volume, and ventricle-to-intracranial volume (ventricle/ICV) ratio. Analyses included nonparametric tests, mixed-effects models, bootstrap resampling, permutation testing, and robust regression.</p><p><strong>Results: </strong>At baseline, shunted patients exhibited larger intracranial volumes (644.3 vs 403.5 mL; p = 0.020) but not ventricular volumes (82.2 vs 34.2 mL; p = 0.072) compared to non-shunted patients. Although the ventricle-to-intracranial volume ratio was significantly higher in shunted patients under 50 days of age (p = 0.026), this difference was no longer significant after adjusting for head circumference and prematurity (p = 0.144). Sensitivity analyses confirmed differences in the neonatal period (p = 0.013), but not in infancy or toddlerhood. Effect-size analyses demonstrated a large difference within 50 days (Hedges' g = 1.268) that diminished thereafter (g = 0.452).</p><p><strong>Conclusion: </strong>Shunted MMC patients demonstrated larger intracranial volumes and higher ventricle/ICV ratios in the neonatal period, but these differences diminished after 50 days. Early ventricular enlargement in this cohort's shunted patients appears robust yet transient, with no sustained volumetric differences between shunted and non-shunted patients later in development.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining the associations between weight, obesity and outcomes of posterior fossa decompression for Chiari malformation in adolescents.","authors":"Victor M Lu, Caleigh S Roach, Steven W Hwang","doi":"10.1007/s00381-026-07401-x","DOIUrl":"10.1007/s00381-026-07401-x","url":null,"abstract":"<p><strong>Background: </strong>Posterior fossa decompression in the setting of Chiari malformation is a common neurosurgical procedure in adolescents; however, the effect of obesity on its surgical outcomes is understudied. This is partly due to the lower incidence of obesity in adolescents requiring higher statistical power. Correspondingly, we sought to interrogate a national surgical database to aggregate a significant cohort size to elucidate possible relationships between obesity and surgical outcomes in this niche.</p><p><strong>Methods: </strong>The American College of Surgeons National Surgical Quality Improvement Program-Pediatric (ACS NSQIP-Pediatric) database from 2015-2024 was interrogated against selection criteria targeting patients aged 10-18 years old surgically treated for Chiari malformation type 1. Adolescent weight was defined by body mass index into categories according to the definitions by Centers for Disease Control and Prevention (CDC). Thirty-day surgical outcomes were modeled using a multivariate logistic regression controlling for covariates across a primary model, and then across various sensitivity models.</p><p><strong>Results: </strong>A total of 4257 patients satisfied selection criteria with a median age of 14.4 years, 65% female and 35% male. Median BMI was 22.7 kg/m², and per CDC definitions 6% were underweight, 51% were healthy weight, 18% were overweight, and 28% were obese (Classes I, II and III). Overall, median length of stay was 3 days, and rates of 30-day reoperation (any), reoperation (related), unplanned readmission and major complications were 3.0%, 2.4%, 5.4%, and 3.5%, respectively. On analysis, categorical obesity (vs. healthy weight/underweight) was independently associated with the 30-day major complication composite (aOR 1.93, p < 0.001) and unplanned readmission (aOR 1.47, p = 0.012). Of the complications, surgical site infection (p < 0.001) and peripheral nerve injury (p = 0.011) were statistically more common in the obese group than others. As a continuous predictor, each + 1 SD increase in BMI-for-age z-score was independently associated with higher adjusted odds of 30-day major complication (aOR 1.25, p = 0.004) and unplanned readmission (aOR 1.13, p = 0.038). Finally, linear trend tests across all six CDC extended categories were significant for 30-day reoperation (any) (p = 0.031), reoperation (related) (p = 0.005), and unplanned readmission (p = 0.017).</p><p><strong>Conclusion: </strong>In adolescents, there is a clear postoperative profile that exists 30-days after posterior fossa decompression for Chiari malformation based on weight and obesity. This profile is defined by increased morbidity rather than mortality, and future studies are needed to determine how these findings can be effectively integrated into preoperative evaluation and prehabilitation workup for patients to optimize surgical outcomes further.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic posterior vault distraction osteogenesis (PVDO): advantages of eliminating the bicoronal incision.","authors":"Philip D Tolley, Maura R Guyler, Isabel A Ryan, Elizabeth B Card, Adam J Kundishora, Jordan W Swanson","doi":"10.1007/s00381-026-07391-w","DOIUrl":"10.1007/s00381-026-07391-w","url":null,"abstract":"<p><p>Cranial vault modeling for children with craniosynostosis is traditionally performed utilizing an open bicoronal approach. For patients with multi-suture craniosynostosis, particularly bilateral coronal suture fusion, posterior vault expansion using cranial springs or distractors is increasingly utilized. Posterior vault distraction osteogenesis (PVDO) enables substantial expansion of intracranial volume, minimizes relapse, and corrects cranial dysmorphology. However, the burden of a large bicoronal scar remains challenging for patients and families. Minimally invasive endoscopic approaches used primarily for single-suture craniosynostosis allow for decreased blood loss, shorter hospital stay, and decreased scar burden. However, minimally invasive techniques have not yet been realized for PVDO, for several reasons including the safe navigation of venous anatomy. In this report, the authors describe a novel technique utilizing a minimally invasive endoscopic PVDO technique (PV En-DO) that avoids a bicoronal incision and present an initial case report demonstrating feasibility in patients with bicoronal craniosynostosis. The authors conclude that PV En-DO appears feasible, safe, and effective, offering adequate cranial vault expansion with reduced scar burden and advantageous perioperative characteristics. Further study is needed to elucidate the indications, safety, and long-term outcomes of this technique.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13391445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148564371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robert Kennedy (1865-1924) and the first surgical repair of neonatal brachial plexus palsy.","authors":"Mario G Siqueira, Roberto S Martins, Bruno S A G Freitas, Carlos O Heise","doi":"10.1007/s00381-026-07375-w","DOIUrl":"10.1007/s00381-026-07375-w","url":null,"abstract":"<p><p>This historical vignette highlights key aspects of the professional life of the Scottish surgeon Robert Kennedy and details the first reported surgical repair cases of brachial plexus birth palsy, which achieved remarkably favorable outcomes. These cases represent the first documented attempt at surgical reconstruction of neonatal brachial plexus palsy and predate the modern era of nerve surgery by several decades.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148521736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}