Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery最新文献

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Addressing unilateral lambdoid craniosynostosis using endoscopic suturectomy and barrel-stave osteotomies: surgical technique and literature review.
IF 1.2
Sandi Lam, Kiichiro Yaguchi, William M Tian, Breanna Baltrusch, Shunsuke Yuzuriha, Akira Yamada
{"title":"Addressing unilateral lambdoid craniosynostosis using endoscopic suturectomy and barrel-stave osteotomies: surgical technique and literature review.","authors":"Sandi Lam, Kiichiro Yaguchi, William M Tian, Breanna Baltrusch, Shunsuke Yuzuriha, Akira Yamada","doi":"10.1007/s00381-026-07489-1","DOIUrl":"https://doi.org/10.1007/s00381-026-07489-1","url":null,"abstract":"<p><strong>Purpose: </strong>Unilateral lambdoid craniosynostosis (ULC) is a rare cranial deformity requiring intervention to correct asymmetry of the posterior skull. Conventional open remodeling and distraction osteogenesis offer robust expansion but carry risks of higher blood loss, hardware complications, or reoperation. We report a novel, minimally invasive technique combining endoscopic lambdoid suturectomy with barrel-stave osteotomies, supplemented by a literature review.</p><p><strong>Case description: </strong>A 2-month-old healthy male presented with classic left ULC features, including occipitoparietal flattening, ipsilateral mastoid bulge, contralateral parietal bulge, and ear level asymmetry, confirmed by 3D computed tomography. Under endoscopic guidance through two small incisions, a 10-cm-long by 1.2-cm-wide lambdoid suturectomy was performed. To enhance immediate intraoperative expansion, seven 3-cm barrel-stave osteotomies were placed perpendicularly along the superior (4 cuts) and inferior (3 cuts) suture margins and gently greenstick-fractured outward. The estimated blood loss was 10 mL without perioperative complications. Postoperative cranial molding helmet therapy was initiated on day 10. At the 4-month follow-up visit, 3D surface scanning demonstrated marked improvement in head shape and symmetry.</p><p><strong>Conclusions: </strong>Our method, endoscopic suturectomy and barrel-stave osteotomies on a single patient with unilateral lambdoid craniosynostosis, demonstrated safe and favorable outcomes. We believe the addition of barrel-stave osteotomies to suturectomy may yield superior clinical outcomes, compared to conventional endoscopic-assisted procedures with suturectomy alone. However, it is necessary to accumulate a larger number of cases and conduct long-term follow-up studies to further validate this hypothesis.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149241062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Craniovertebral junction injuries in children: a single center retrospective review. 儿童颅椎交界处损伤:一项单中心回顾性研究。
IF 1.2
Debajyoti Datta, Lianne Brandt, Kaylea N MacDonald, Suna Jung, Albert Tu
{"title":"Craniovertebral junction injuries in children: a single center retrospective review.","authors":"Debajyoti Datta, Lianne Brandt, Kaylea N MacDonald, Suna Jung, Albert Tu","doi":"10.1007/s00381-026-07494-4","DOIUrl":"https://doi.org/10.1007/s00381-026-07494-4","url":null,"abstract":"<p><strong>Objectives: </strong>The craniovertebral junction is a unique structure consisting of the occipito-atlantal and atlanto-axial joints and their associated ligaments. The aim of the present study was to characterize the presentation, underlying mechanism of trauma, clinical and radiological findings, management, and outcome of children with craniovertebral junction injury treated in our institution.</p><p><strong>Methods: </strong>We undertook a retrospective review of all patients with craniovertebral junction injuries treated at our institution between January 2016 and June 2024. Craniovertebral junction injury was defined as presence of one or more of (i) bony fracture or dislocation of the occipital condyles and/or any part of the atlas or axis, (ii) atlanto-axial dislocation/subluxation identified as per standard radiological criteria as described in literature, (iii) ligamentous injury identified on MRI or instability identified on dynamic imaging, and (iv) spinal extra-axial and spinal parenchymal hemorrhage at the level of craniovertebral junction. Patients who had non-traumatic anomalies of the craniovertebral junction and who had incomplete records were excluded from the study.</p><p><strong>Results: </strong>From 732 patients who underwent imaging evaluation at the emergency department for traumatic cervical spine injury, we identified 33 patients who met our inclusion criteria for craniovertebral junction injury. Motor vehicle accidents were the most common cause of injury, with the majority of patients suffering from ligamentous injury. Fractures of the occipital condyle were the most common bony injury of the craniovertebral junction. Most of the patients had good neurological outcomes, with mortality reported in 2/33. Multiple correspondence analysis identified a high-severity phenotype characterized by CVJ injury together with neurological and systemic compromise. An exploratory eight-item CVJ Injury Score was derived to characterize this phenotype.</p><p><strong>Conclusion: </strong>Craniovertebral junction injury in children is relatively rare, occurring in 4.5% of patients undergoing imaging evaluation for cervical spine injury in our series. It encompasses a broad clinical spectrum, ranging from injuries successfully managed non-operatively to severe injuries associated with neurological, vascular, and systemic physiological compromise. The proposed CVJ Injury Score represents an exploratory framework for characterizing this high-severity phenotype and requires external multicenter validation.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term outcomes of pediatric medulloblastoma before routine molecular classification: a 20-year single-center cohort study. 常规分子分类前儿童髓母细胞瘤的长期预后:一项20年单中心队列研究。
IF 1.2
Mehtap Ertekin, Aytul Temuroglu, Gokalp Rustem Aksoy, Mevlut Ozgur Taskapilioglu, Betul Sevinir
{"title":"Long-term outcomes of pediatric medulloblastoma before routine molecular classification: a 20-year single-center cohort study.","authors":"Mehtap Ertekin, Aytul Temuroglu, Gokalp Rustem Aksoy, Mevlut Ozgur Taskapilioglu, Betul Sevinir","doi":"10.1007/s00381-026-07496-2","DOIUrl":"https://doi.org/10.1007/s00381-026-07496-2","url":null,"abstract":"<p><strong>Purpose: </strong>Medulloblastoma is the most common malignant brain tumor of childhood. Although molecular classification has refined prognostication, long-term real-world outcomes from periods or settings without routine molecular subtyping remain clinically relevant. We report a 20-year single-center experience from a tertiary pediatric oncology center in Turkey.</p><p><strong>Methods: </strong>We retrospectively analyzed 97 children diagnosed with Medulloblastoma at Uludag University between 2000 and 2020. Survival status was updated through 2025. Overall survival (OS) and event-free survival (EFS) were estimated using Kaplan-Meier analysis. Prognostic factors were assessed using log-rank tests and multivariate Cox regression for OS and EFS. Late effects among survivors were recorded.</p><p><strong>Results: </strong>The cohort included 56 males and 41 females, with a median age of 7.0 years. Five-year OS and EFS were 73.9% and 69.9%, respectively, with a median follow-up of 70.2 months. Five-year OS improved from 57.1% in 2000-2010 to 83.6% in 2011-2020. Later treatment era independently predicted improved OS (HR, 0.30; 95% CI, 0.14-0.65; p = 0.002) and EFS (HR, 0.38; 95% CI, 0.20-0.75; p = 0.005). Anaplastic/large-cell histology independently predicted poorer OS and EFS. Baseline characteristics were largely similar between eras, although median age differed. Late effects were documented in 56 of 68 survivors (82%), most commonly motor or cerebellar dysfunction, growth failure, neurocognitive impairment, and hypothyroidism.</p><p><strong>Conclusion: </strong>Survival improved across treatment eras and was not readily explained by a more favorable measured case mix. These findings provide pre-molecular era real-world benchmarks and highlight the importance of treatment standardization and structured survivorship care.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of tumor biopsy in children with obstructive hydrocephalus treated with endoscopic third ventriculostomy: a single-center experience. 内镜下第三脑室造口术治疗梗阻性脑积水的儿童肿瘤活检的作用:单中心经验。
IF 1.2
Ryszard Sordyl, Natalia Wyroba, Justyna Karliczek, Wiktoria Pniok, Marek Mandera
{"title":"The role of tumor biopsy in children with obstructive hydrocephalus treated with endoscopic third ventriculostomy: a single-center experience.","authors":"Ryszard Sordyl, Natalia Wyroba, Justyna Karliczek, Wiktoria Pniok, Marek Mandera","doi":"10.1007/s00381-026-07493-5","DOIUrl":"10.1007/s00381-026-07493-5","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to present and analyze our institutional experience with endoscopic third ventriculostomy (ETV), performed alone or in combination with simultaneous tumor biopsy, for the management of obstructive hydrocephalus in pediatric patients.</p><p><strong>Methods: </strong>A retrospective analysis was conducted of the medical records of pediatric patients with tumor-related obstructive hydrocephalus who underwent ETV between 2013 and 2024.</p><p><strong>Results: </strong>Thirty-five children underwent ETV at a mean age of 9.2 years. Hydrocephalus was most commonly associated with lesions located in the tectal plate (65.7%). In 12 cases (34.3%), ETV was combined with an endoscopic tumor biopsy. Over a median follow-up of 3.3 years, the overall ETV effectiveness was 82.9% (n = 29). Postoperative complications occurred in 7 patients (20.0%), with the most frequent being transient cerebrospinal fluid (CSF) leakage from the surgical wound (n = 3; 42.9%). Histological results of endoscopic tumor biopsy were successfully obtained from 10 of 12 (83.3%) samples. No statistically significant differences in rates of reoperation, shunt implantation, or tumor resection were observed between patients with ETV alone and those with ETV with biopsy.</p><p><strong>Conclusions: </strong>ETV is an effective treatment for tumor-related obstructive hydrocephalus in children that may be safely combined with endoscopic tumor biopsy in selected cases, enabling early histopathological diagnosis and timely initiation of oncological treatment while potentially reducing the need for subsequent open surgical procedures.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical presacral masses in Currarino syndrome: a case series. Currarino综合征的非典型骶前肿块:一个病例系列。
IF 1.2
Ravi Ameet Patel, Rebecca Du, Erin Rowell, Julia E Grabowski, Pouya Jamshidi, Nitin R Wadhwani, Farres Obeidin, Jared T Ahrendsen, Jean-Paul Wolinsky, Robin Bowman
{"title":"Atypical presacral masses in Currarino syndrome: a case series.","authors":"Ravi Ameet Patel, Rebecca Du, Erin Rowell, Julia E Grabowski, Pouya Jamshidi, Nitin R Wadhwani, Farres Obeidin, Jared T Ahrendsen, Jean-Paul Wolinsky, Robin Bowman","doi":"10.1007/s00381-026-07486-4","DOIUrl":"10.1007/s00381-026-07486-4","url":null,"abstract":"<p><strong>Introduction: </strong>Currarino syndrome is a rare congenital disorder classically defined by the triad of sacral anomaly, anorectal malformation, and a presacral mass. While anterior meningoceles and teratomas are the most commonly reported lesions, an expanding body of literature suggests a broader spectrum of presacral pathology. We present three cases from our institution that expand the phenotypic range of presacral masses associated with Currarino syndrome, including lesions not previously well described in this population.</p><p><strong>Case presentation: </strong>Three cases are presented. Final pathologic diagnoses included myxopapillary ependymoma, mature cystic teratoma, and neuroendocrine tumor arising within a teratoma.</p><p><strong>Conclusion: </strong>These cases highlight the considerable heterogeneity of presacral lesions in Currarino syndrome and identify two underrecognized or previously unreported tumor types: myxopapillary ependymoma and neuroendocrine tumor. Surgical management must be individualized and often requires a multidisciplinary approach. Future studies will further clarify genotype-phenotype relationships and improve diagnostic and management strategies in this complex syndrome.</p><p><strong>Established facts: </strong>Currarino syndrome is a rare congenital disorder classically defined by the triad of sacral anomaly, anorectal malformation, and a presacral mass. Presacral masses are most commonly anterior meningoceles and teratomas. A wider spectrum of lesions has been reported, underscoring the complexity of the syndrome and the importance of thorough evaluation and management of presacral pathology.</p><p><strong>Novel insights: </strong>In Case 1, we report a previously undescribed association of myxopapillary ependymoma with a retrorectal teratoma in the setting of Currarino syndrome. Case 2 illustrates the potential for significant enlargement of presacral meningoceles with associated teratomas with a rare instance of prenatal diagnosis by ultrasound. Case 3 expands the spectrum of presacral pathology in Currarino syndrome by demonstrating a neuroendocrine tumor.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13658381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Timing of radiotherapy and autologous stem cell transplantation in embryonal tumor with multilayered rosettes: a critical narrative review. 放疗时机和自体干细胞移植在胚胎肿瘤多层玫瑰花:一个关键的叙事回顾。
IF 1.2
Sudarshawn Damodharan
{"title":"Timing of radiotherapy and autologous stem cell transplantation in embryonal tumor with multilayered rosettes: a critical narrative review.","authors":"Sudarshawn Damodharan","doi":"10.1007/s00381-026-07490-8","DOIUrl":"10.1007/s00381-026-07490-8","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;Embryonal tumor with multilayered rosettes (ETMR) carries a median overall survival of approximately 10-12 months despite maximal-safe resection, high-dose chemotherapy (HDCT) with autologous stem cell transplantation (ASCT), and radiotherapy (RT). RT has historically been deferred or omitted in these predominantly infant-age patients owing to concerns over neurodevelopmental toxicity, with HDCT/ASCT serving as the principal consolidation strategy. More recent data have called this approach into question. This narrative review synthesizes the evidence on the timing of RT relative to HDCT/ASCT and its association with outcome in ETMR.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A structured narrative review of PubMed, EMBASE, and the Cochrane Library (2000-2025) identified studies reporting ETMR-specific outcomes with extractable data on RT timing relative to ASCT. Major prospective trials (ACNS0334 and P-HIT/HIT2000) and institutional or registry series (n ≥ 4 molecularly or histopathologically confirmed ETMR patients) were considered.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Nine studies or study-level cohorts providing ETMR-specific RT-timing data were identified, including the Rare Brain Tumor Registry cohort of 159 molecularly confirmed patients. Across independent cohorts, early RT administered within approximately six weeks of surgery or before protracted HDCT/ASCT is consistently overrepresented among long-term survivors (&gt; 36 months): 10 of 26 (38%) in one literature survey and near-universal RT (17/18; 94%) in another. In the Rare Brain Tumor Registry, two-year event-free survival after gross total resection was 66% with HDCT plus RT versus 21% with HDCT and no RT, and 0% with conventional chemotherapy without RT. Radiation-sparing protocols (ACNS0334) showed predominantly local failure (88%), with salvage RT after progression providing no durable benefit. Tandem HDCT/ASCT without upfront RT (P-HIT/HIT2000) produced a five-year OS of 47% for the carboplatin-etoposide plus tandem-HDCT backbone, superior to other chemotherapy regimens but with frequent on-treatment relapse and no independent prognostic benefit demonstrable for radiotherapy as delivered. Combined RT and HDCT/ASCT was associated with improved survival in some series but, in a small series treated with tandem ASCT, with a high incidence of pseudoprogression and neurocognitive impairment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Current evidence indicates that RT deferral beyond the HDCT/ASCT consolidation window is associated with inferior local control and worse long-term outcomes in ETMR. PNOC031, a prospective but nonrandomized trial that assigns RT-eligible patients to early focal RT and RT-ineligible patients to HDCT/ASCT in parallel cohorts, together with future prospective studies, should help to resolve this. Pending those results, and recognizing that the supporting data are observational and subject to selection bias, early focal RT following gross-total resectio","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serious methodological and numerical concerns regarding a meta-analysis of hypertonic saline versus mannitol in pediatric intracranial hypertension. 关于高渗盐水与甘露醇治疗儿童颅内高压的荟萃分析的严重方法学和数值问题。
IF 1.2
Omar Fayek Ismail, Shabina Bibi
{"title":"Serious methodological and numerical concerns regarding a meta-analysis of hypertonic saline versus mannitol in pediatric intracranial hypertension.","authors":"Omar Fayek Ismail, Shabina Bibi","doi":"10.1007/s00381-026-07455-x","DOIUrl":"10.1007/s00381-026-07455-x","url":null,"abstract":"","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safe electrophysiology-guided resection of an epileptogenic non-exophytic hamartoma at the floor of the fourth ventricle in a child. 电生理学引导下安全切除儿童第四脑室底癫痫性非外生性错构瘤。
IF 1.2
Anaïs Chivet, Julie Bonheur, Diane Doummar, Sarah Ferrand-Sorbets, Laurent Goetz, Georg Dorfmuller
{"title":"Safe electrophysiology-guided resection of an epileptogenic non-exophytic hamartoma at the floor of the fourth ventricle in a child.","authors":"Anaïs Chivet, Julie Bonheur, Diane Doummar, Sarah Ferrand-Sorbets, Laurent Goetz, Georg Dorfmuller","doi":"10.1007/s00381-026-07485-5","DOIUrl":"10.1007/s00381-026-07485-5","url":null,"abstract":"<p><p>Hamartoma of the floor of fourth ventricle (HFFV) is an extremely rare entity known to be causing focal movement disorders in children. According to the few reported cases in literature, the only effective treatment is disconnection or resection of the lesion which can be very challenging in this anatomic area. We report a 15-year-old child with a fourth ventricle floor's limited nonexophytic hamartoma revealed by brief paroxysmal movement disorder episodes since the age of 5 months, without EEG correlate. He was treated for the first time by safe surgical electrophysiology-guided resection, with promising results on epileptic disease. This positive result opens interesting prospects for improving the surgical management of other lesions affecting this anatomical region, while limiting postoperative neurological deficits.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149122556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barometric pressure variability and shunt-related hospital encounters in the pediatric population: a retrospective analysis. 儿科人群中气压变异性和分流相关的医院就诊:回顾性分析
IF 1.2
Rebecca White, April Gormon, Duc T Nguyen, Travis Herzog, Daniel Curry
{"title":"Barometric pressure variability and shunt-related hospital encounters in the pediatric population: a retrospective analysis.","authors":"Rebecca White, April Gormon, Duc T Nguyen, Travis Herzog, Daniel Curry","doi":"10.1007/s00381-026-07469-5","DOIUrl":"10.1007/s00381-026-07469-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study's objective was to investigate barometric pressure changes that are most strongly associated with symptom exacerbations in shunted hydrocephalus patients. To achieve this, we conducted in-depth analysis of hospital encounter data and examined their correlation with variations in sea level pressure (SLP). Ultimately, our findings may inform hydrocephalus management strategies by identifying potential environmental triggers, reducing unnecessary hospital visits, and guiding the future design of CSF diversion technologies that are more responsive to external conditions.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of the daily hydrocephalus encounters census of a tertiary children's hospital and compared it with weather parameters, including fluctuations in SLP as measured in 8-h intervals, maximum daily rate of change, daily minimum SLP, and daily mean SLP. Data was analyzed in a univariate and multivariable Poisson generalized linear models, and census was compared to weather fluctuations on the day of encounter, the following day, and 2 days afterward.</p><p><strong>Results: </strong>In univariable analysis, hydrocephalus encounters were associated with the daily maximum rate of change, daily maximum SLP, daily minimum SLP, and daily mean SLP. These associations maintained 1 day and 2 days after the hospital encounters. In multivariate analysis, the daily maximum SLP and daily minimum SLP were associated with patient encounters both 1 and 2 days after the analyzed census date. Associations were also observed between daily minimal SLP, daily maximum SLP, and maximum daily 8-h SLP.</p><p><strong>Conclusion: </strong>This study documents an association between fluctuations in atmospheric pressure and daily hydrocephalus census at a single tertiary medical center. Weather-related influences should be considered when evaluating shunt malfunction in patients with chronic shunted hydrocephalus.</p>","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149122478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: The management of pediatric Chiari I malformation with concomitant hydrocephalus: a multicenter retrospective analysis. 致编辑的信:一项多中心回顾性分析:小儿甲型囊状体畸形伴脑积水的治疗。
IF 1.2
Ladina Greuter, Tim Jonas Hallenberger, Maria Licci, Ulrich-Wilhelm Thomale, Valentina Pennacchietti, Andrea Bartoli, Mahmoud Messerer, Agne Andriuskeviciute, Marta Garvayo, Malte Otenhausen, Verena Fassel, Conor Mallucci, Arthur R Kurzbuch, Giuseppe Cinalli, Guiseppe Mirone, Christopher Chandler, Sanjeev Bassi, Martina Messing-Jünger, Katharina Lutz, Dieter Class, Jonathan Roth, Shlomi Constantini, Carla Richetta, Raphael Guzman, Jehuda Soleman
{"title":"Letter to the editor: The management of pediatric Chiari I malformation with concomitant hydrocephalus: a multicenter retrospective analysis.","authors":"Ladina Greuter, Tim Jonas Hallenberger, Maria Licci, Ulrich-Wilhelm Thomale, Valentina Pennacchietti, Andrea Bartoli, Mahmoud Messerer, Agne Andriuskeviciute, Marta Garvayo, Malte Otenhausen, Verena Fassel, Conor Mallucci, Arthur R Kurzbuch, Giuseppe Cinalli, Guiseppe Mirone, Christopher Chandler, Sanjeev Bassi, Martina Messing-Jünger, Katharina Lutz, Dieter Class, Jonathan Roth, Shlomi Constantini, Carla Richetta, Raphael Guzman, Jehuda Soleman","doi":"10.1007/s00381-026-07466-8","DOIUrl":"10.1007/s00381-026-07466-8","url":null,"abstract":"","PeriodicalId":520587,"journal":{"name":"Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery","volume":"42 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149122463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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