Annals of behavioral medicine : a publication of the Society of Behavioral Medicine最新文献

{"title":"Race differences in the effect of obesity on inflammation among Black and White older adults who quit smoking: a longitudinal analysis of the Health and Retirement study.","authors":"Marcia M Tan, Tiwaloluwa A Ajibewa, John Cursio, Donald Hedeker, Andres Mauricio Garcia-Sierra, Dedeepya Konuthula, Nancy C Jao","doi":"10.1093/abm/kaag057","DOIUrl":"10.1093/abm/kaag057","url":null,"abstract":"<p><strong>Importance: </strong>Race differences in inflammation have been attributed to higher body mass index (BMI); however, few studies have comprehensively examined whether changes in obesity influence changes in C-reactive protein (CRP) by race, particularly following smoking cessation.</p><p><strong>Objective: </strong>As CRP declines after quitting smoking, the current study examined whether longitudinal changes in multiple measures of obesity were differentially associated with CRP change among non-Hispanic Black (NHB) and non-Hispanic White (NHW) older adults who formerly smoked.</p><p><strong>Design: </strong>This is a longitudinal analysis of the Health and Retirement Study, nationally representative study of US adults. Participants were matched on self-reported demographic, socioeconomic, and behavioral factors using propensity score analysis to control for the effects of social disadvantage. C-reactive protein, waist circumference, body weight, and BMI were assessed in 2006, 2010, and 2014. Linear mixed models examined race differences in the effects of time-varying obesity on CRP change (n = 899 observations).</p><p><strong>Results: </strong>C-reactive protein significantly declined over time (β = -0.23, p < .0001). However, no differences in CRP change were found between NHBs (n = 146) and NHWs (n = 245). Only weight was positively associated with CRP change over time (β = 0.002, p < .001).</p><p><strong>Conclusions and relevance: </strong>In our matched sample, there were no race differences in CRP decline among older adults, and only weight was associated with a lessened decline over time. Our findings suggest that weight alone may be an important predictor of CRP in older adults rather than BMI, which has been studied extensively in previous research.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological factors as mediators of the effectiveness of telehealth mindfulness-based interventions for pain and pain-related conditions.","authors":"Stephanie L Taylor, Collin Calvert, Alexander C Haley, Roni Evans, Jenna Adamowicz, Kelli D Allen, Gert Bronfort, Lee J S Cross, Elizabeth S Goldsmith, Alexis Grant, Brent Leininger, Marianne S Matthias, J Greg Serpa, Brent C Taylor, Diana J Burgess","doi":"10.1093/abm/kaag061","DOIUrl":"10.1093/abm/kaag061","url":null,"abstract":"<p><strong>Importance: </strong>Mindfulness meditation is an evidence-based therapy for chronic pain for which some have explored possible mechanisms of action. However, these mechanisms can vary widely depending on the mindfulness-based intervention (MBI).</p><p><strong>Objective: </strong>To study possible mechanisms of action of 2 similar MBIs for pain.</p><p><strong>Design: </strong>We used data from our learning to apply mindfulness to pain (LAMP) pragmatic randomized controlled trial comparing usual care with virtual group or self-paced MBIs. The LAMP MBIs included education on adaptive pain behaviors and mindfulness and used shorter, less formal mindfulness practice than standard MBIs. We examined whether mindfulness, pain self-efficacy, pain catastrophizing, and stress mediated the treatment effects on 2 pain and 7 pain-related biopsychosocial outcomes at 10 weeks and 6 months using mediation models.</p><p><strong>Results: </strong>The MBIs improved pain catastrophizing, pain self-efficacy, and mindfulness but did not affect perceived stress. Pain catastrophizing and pain self-efficacy had large mediating effects between the MBIs and pain interference, pain intensity, physical functioning, social functioning, anxiety, fatigue, sleep disturbance, depression, and post-traumatic stress disorder. mindfulness also mediated the above relationships with smaller effects between MBIs and all outcomes except for pain interference, pain intensity, physical functioning, and social functioning.</p><p><strong>Conclusions: </strong>Reduced pain catastrophizing and increased pain self-efficacy were apparent mechanisms of action improving pain interference, pain intensity, and other biopsychosocial outcomes in our MBIs, whereas increased mindfulness was the apparent mechanism of action improving psychological and sleep-related outcomes. This study improves our understanding of mechanisms by which MBIs can affect pain and important pain-related outcomes.</p><p><strong>Study registration and analytic plan registration: </strong>clinicaltrials.gov. Identifier: NCT04526158.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy on the rocks: how hazardous drinking contextualizes the path from internalized heterosexism to antiretroviral adherence via adherence self-efficacy.","authors":"Stephen D Ramos, Wilson Vincent, Daniel E Siconolfi, Keith J Horvath, Chadwick K Campbell, Susan M Kegeles, Erik D Storholm","doi":"10.1093/abm/kaag019","DOIUrl":"10.1093/abm/kaag019","url":null,"abstract":"<p><strong>Background: </strong>Young Black sexual minority men living with HIV (YBSMM+) in the US South face a confluence of structural and psychosocial barriers that impact antiretroviral therapy (ART) adherence. Internalized heterosexism and hazardous drinking have emerged as significant yet understudied factors influencing adherence self-efficacy, a known determinant of sustained ART adherence.</p><p><strong>Purpose: </strong>This study examined the relationships among internalized heterosexism, adherence self-efficacy, and ART adherence in a sample of YBSMM+, with a particular focus on the moderating role of hazardous drinking.</p><p><strong>Methods: </strong>Utilizing cross-sectional survey data from a community-based sample of YBSMM+ in the US South, we conducted moderated mediation analyses to assess the direct and indirect effects of internalized heterosexism on ART adherence via adherence self-efficacy, as well as whether hazardous drinking moderates the direct effect of internalized heterosexism on adherence self-efficacy.</p><p><strong>Results: </strong>Findings indicated that higher levels of internalized heterosexism were associated with lower adherence self-efficacy, which in turn predicted lower ART adherence. Adherence self-efficacy significantly mediated the relationship between internalized heterosexism and ART adherence, replicating prior research. Moreover, participants who reported hazardous drinking evidenced a stronger inverse association between internalized heterosexism and adherence self-efficacy than those who did not report hazardous drinking.</p><p><strong>Conclusions: </strong>The results underscore the complex interplay among internalized heterosexism, adherence self-efficacy, and hazardous drinking in shaping ART adherence among YBSMM+. Interventions targeting adherence self-efficacy and addressing hazardous drinking, while also directly addressing internalized stigma, may help buffer the harmful effects of these factors and support improved HIV health outcomes in this population.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A mixed-methods investigation of firearm experiences among sexual and gender minority young adults of color in Detroit.","authors":"Kristi E Gamarel, Laura Jadwin-Cakmak, Wesley M Correll-King, Ini-Abasi Ubong, Avery R Everhart, Dior' Monro, J Stephenson, Janae N Best, Kalaan Scott, Sydney N Strunk, Kerith Conron, Maureen Connolly, Patrick M Carter, Marc A Zimmerman","doi":"10.1093/abm/kaag027","DOIUrl":"10.1093/abm/kaag027","url":null,"abstract":"<p><strong>Background: </strong>Firearm violence is a pressing public health crisis in the United States and disproportionately impacts sexual and gender minority (SGM) young adults of color who already face systemic inequities. Despite elevated risks of suicidality and violence victimization, firearm violence research rarely focuses on SGM populations.</p><p><strong>Purpose: </strong>This study examined firearm experiences among SGM young adults of color in Detroit, MI, to inform trauma-informed care, firearm safety education, and inclusive prevention strategies.</p><p><strong>Methods: </strong>Using a community-engaged convergent parallel mixed-methods design, we integrated survey data and in-depth qualitative interviews. Participants (N = 24; aged 18-29) were recruited through a community health center serving SGM young adults of color. Surveys assessed firearm behaviors, interpersonal and community exposures, and safety perceptions. Reflexive thematic analysis was applied to interview.</p><p><strong>Results: </strong>Qualitative data revealed pervasive trauma linked to firearm violence, eroding mental health and feelings of safety. Transgender women in the sample described vulnerability to intimate partner firearm violence, while sexual minority cisgender men described violence in public spaces. Participants described firearms as both normalized and necessary for protection and noted a lack of culturally relevant firearm safety education. Quantitative findings from this small, purposive sample indicated that over half reported carrying or using a firearm (52.4%), two-thirds had been shot at (66.7%), and 42.9% experienced intimate partner firearm threats.</p><p><strong>Conclusions: </strong>Findings highlight the urgency of integrating trauma-informed care into SGM health services, developing inclusive firearm safety initiatives, and reinstating sexual orientation and gender identity measures in surveillance systems to better track inequities and inform prevention policy.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise effectiveness on fatigue in Long-COVID: systematic review and meta-analysis.","authors":"Yi-Chun Chen, Hui-Ting Yang, Chu-Fang Wu, Chia-Chi Kuo","doi":"10.1093/abm/kaag048","DOIUrl":"10.1093/abm/kaag048","url":null,"abstract":"<p><strong>Background: </strong>Patients with Long COVID commonly experience fatigue-related distress, often leading to low energy, reduced activity endurance, and exertional dyspnea, all of which negatively impact quality of life. Although studies have increasingly explored the effects of exercise on Long COVID-related fatigue, a comprehensive synthesis of the evidence is lacking.</p><p><strong>Purpose: </strong>To examine the effectiveness of exercise in improving fatigue among patients with Long COVID through a systematic review and meta-analysis.</p><p><strong>Methods: </strong>This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and the Joanna Briggs Institute (JBI) methodology for systematic reviews of effectiveness. Airiti Library, Cumulative Index to Nursing and Allied Health, Cochrane Library, Embase, PubMed, ProQuest, and Index of the Taiwan Periodical Literature System databases were searched before July 2025. Two reviewers used the JBI randomized controlled trial checklist to assess the methodological quality of included studies. Extracted data were entered and analyzed using RevMan 5.4 software. Inverse variance and Mantel-Haenzel random effect model was used to estimate effect sizes. Subgroup and sensitivity analysis were performed.</p><p><strong>Results: </strong>Fourteen randomized controlled trials were reviewed. Meta-analysis reveals that the exercise training group significantly improved fatigue severity (standardized mean difference [SMD] = -0.59, P = .002) and dyspnea severity (SMD = -0.89, P = .005) compared to the usual care group. Improvements were also observed in muscle strength and endurance.</p><p><strong>Conclusions: </strong>Exercise training may help reduce physiological and psychological fatigue in patients with Long COVID. The available evidence suggests that individualized single-modality and multimodal exercise programs may be beneficial for patients experiencing fatigue symptoms. The included interventions generally consisted of 30-60 min sessions, performed 3-6 times per week over at least 8-12 weeks. However, given the moderate-to-very-low certainty of the evidence, exercise programs should be individualized based on patient response and tolerance. Particular attention should be paid to preventing postexertional malaise, with the goal of reducing fatigue and supporting the recovery of daily functioning in patients with Long COVID.</p><p><strong>Trial registration: </strong>PROSPERO: CRD420251113419 https://www.crd.york.ac.uk/PROSPERO/view/CRD420251113419.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying momentary predictors of physical activity intentions and behavior among behavioral weight loss participants.","authors":"Rebecca J Crochiere, Devika Goel, Ivy Dang, Ashley Kim, Leah M Schumacher, Fengqing Zhang, Danielle Arigo","doi":"10.1093/abm/kaag043","DOIUrl":"https://doi.org/10.1093/abm/kaag043","url":null,"abstract":"<p><strong>Background: </strong>Many participants in behavioral weight loss (BWL) programs struggle to meet the moderate-to-vigorous physical activity (MVPA) prescription. Elucidating momentary predictors of MVPA in BWL programs could improve targeting of risk/protective factors, which may boost MVPA adherence and enhance weight control; yet this remains unstudied.</p><p><strong>Purpose: </strong>To examine momentary factors as potential predictors of MVPA intentions, behavior, and the intention-behavior gap among BWL participants.</p><p><strong>Methods: </strong>Participants (N = 116) were adults with overweight/obesity in a 12-week remote BWL intervention that prescribed 150 minutes of MVPA/week. Participants wore Fitbits (measuring MVPA) and received 6 daily ecological momentary assessments (EMA; brief, smartphone-delivered surveys) for 2-week periods at treatment initiation, mid-treatment, and end-of-treatment. EMA measured MVPA intention and 11 potential predictors of MVPA intentions/behaviors (based on empirical support from non-BWL contexts). Multilevel models tested within-person relations between predictors and MVPA outcomes, controlling for survey number per day, weekday/weekend status, and assessment period.</p><p><strong>Results: </strong>Stress, tiredness, and pain/discomfort negatively predicted MVPA intention, whereas energy, positive affect, a positive social interaction, self-control, self-efficacy, and self-compassion positively predicted MVPA intention. Tiredness negatively predicted MVPA behavior, whereas energy, positive affect, self-control, body satisfaction, and self-efficacy positively predicted MVPA. Tiredness also predicted increased odds of an intention-behavior gap.</p><p><strong>Conclusions: </strong>This study identified 9 momentary predictors of MVPA intentions, 6 predictors of MVPA engagement, and 1 predictor of the MVPA intention-behavior gap in a BWL program. These findings identify potential intervention targets, and momentary digital interventions may try to modify or provide support around these factors in real-time to facilitate MVPA.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masculine norms predict lower COVID-19 prevention behavior: a longitudinal investigation of American men during phase I of the pandemic.","authors":"Laurel M Peterson, Sarah H DiMuccio, Marie Helweg-Larsen, Jing Aeriel Lin","doi":"10.1093/abm/kaag039","DOIUrl":"10.1093/abm/kaag039","url":null,"abstract":"<p><strong>Background: </strong>Gender disparities in COVID-19 prevention were likely driven by male gender socialization, but no research has tested beliefs that prospectively connect endorsement of masculine norms to reduced COVID-19 prevention behavior among men.</p><p><strong>Purpose: </strong>We explored whether men's endorsement of masculine norms influenced COVID-19 prevention behavior via illness-related beliefs and prevention intentions.</p><p><strong>Method: </strong>Early in the COVID-19 pandemic (April 2020), American men (N = 355; Mage = 46.61, 78.9% White) reported their baseline prevention behavior, masculine norms, COVID-19 strength beliefs, and prevention intentions. Two weeks later, they reported participation in CDC (Center for Disease Control)-recommended COVID-19 prevention behaviors (eg, social distancing) and willingness to participate in prevention behavior not yet available (eg, COVID-19 vaccination).</p><p><strong>Results: </strong>Mediation models indicated that masculine norms endorsement serially related to greater belief that strength protects against COVID-19, then lower intentions to participate in prevention behaviors, which predicted lower prevention behavior (b = -0.0073, SE = 0.0043, 95% CI, -0.0172 to -0.0004) and future prevention willingness (b = -0.0073, SE = 0.0046, 95% CI, -0.0180 to -0.0004).</p><p><strong>Conclusions: </strong>Masculine norm endorsement indirectly predicted lower COVID-19 prevention behaviors and willingness to participate in emerging prevention behaviors via illness-related beliefs and reduced prevention intentions. These results suggest that masculine norms shape pandemic prevention-related decisions via beliefs that being strong can protect against the virus. Results persisted across demographic differences, political orientation, and severity of regional outbreaks. Public health efforts to reduce gender disparities in pandemics should consider how recommended actions interact with masculine norms and how to leverage interventions to promote men's health.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding social networks through physical activity: implications for cardiometabolic health.","authors":"Becky Marquez, Xinlian Zhang, Dori Pekmezi, Bess Marcus","doi":"10.1093/abm/kaag063","DOIUrl":"10.1093/abm/kaag063","url":null,"abstract":"<p><strong>Importance: </strong>Both social networks (SN) and physical activity (PA) are linked to cardiovascular health, yet prospective studies examining them simultaneously are scarce.</p><p><strong>Objective: </strong>This study examined the temporal relationship between SN and PA as well as the association of both factors with cardiometabolic markers.</p><p><strong>Design: </strong>A 1-year randomized controlled trial.</p><p><strong>Setting: </strong>Remote intervention recruited from San Diego County, California.</p><p><strong>Participants: </strong>Community sample of underactive adult Latinas (N-199).</p><p><strong>Intervention: </strong>Cognitive-behavioral and individually tailored PA program delivered remotely.</p><p><strong>Main outcomes and measures: </strong>The 7-day Physical Activity Recall Interview measured moderate-to-vigorous PA (MVPA) and the Social Network Index Scale measured social network size, social role diversity, close ties (eg, family and friends), and peripheral ties (eg, neighbors and coworkers) at baseline and months 6 and 12. Total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), and triglycerides (TG) were collected from a non-fasting blood sample at baseline and month 6. Data were analyzed using lagged mixed-effect modeling and exploratory multivariable change-score regression.</p><p><strong>Results: </strong>Participants who engaged in greater MVPA subsequently had more peripheral social ties. The reverse association was not observed, as SN did not predict later MVPA. Increased total network size, diverse ties, or peripheral ties were associated with reduced total cholesterol and LDL, but not HDL or TG, independent of concurrent changes in MVPA. No significant associations were detected between MVPA and lipid biomarkers.</p><p><strong>Conclusions and relevance: </strong>Engaging in PA can help cultivate new social relationships. The formation of broader and acquaintance-based social connections may contribute to better cardiometabolic health.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13612171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital cognitive behavioral therapy versus Education for chronic pain in adults with sickle cell disease: 12-month randomized trial results.","authors":"Olubusola B Oluwole, Yi-Fan Chen, Christina M Lalama, Julia A O'Brien, Laura M De Castro, Charles Patrick Carroll, Darla Liles, Nirmish Shah, Santosh L Saraf, Victor R Gordeuk, Leshana Saint Jean, Michael DeBaun, Robert M Cronin, Tonya M Palermo, Sherif M Badawy, Megan E Hamm, Jennifer N Stinson, Chitra Lalloo, Sophie M Lanzkron, Cassandra Trimnell, Lakiea Bailey, Raymona H Lawrence, Kaleab Z Abebe, Charles R Jonassaint","doi":"10.1093/abm/kaag030","DOIUrl":"10.1093/abm/kaag030","url":null,"abstract":"<p><strong>Background: </strong>Chronic pain affects up to 40% of adults with sickle cell disease (SCD), yet treatment options remain limited. While cognitive behavioral therapy (CBT) is effective in other chronic pain conditions, it is underutilized for SCD pain, and its effectiveness remains unclear.</p><p><strong>Purpose: </strong>The Cognitive Behavioral Therapy and Real-time Pain Management Intervention for Sickle Cell via Mobile Applications (CaRISMA) compared digital CBT to Education for chronic SCD pain in adults. At 6 months, the primary outcome (pain interference) showed no between-group difference but both groups improved (CBT: -2.13; Education: -2.66). This report presents 12-month outcomes.</p><p><strong>Methods: </strong>A total of 359 participants with SCD chronic pain were randomized to 12 weeks of digital CBT (n = 181) or Education (n = 178), both with weekly health coach support.</p><p><strong>Results: </strong>At 12 months, 56.5% (n = 203) completed follow-up. No between-group differences in pain interference were observed [0.43, 95% CI, -1.61 to 2.48; P = .68]; however, both groups sustained improvement from baseline (CBT: -1.50; Education: -1.93). Cognitive behavioral therapy participants reported greater improvement in emotional impact [2.00, 95% CI, 0.12-3.88; P = .04], while pain intensity, depression, anxiety, and opioid misuse did not differ between groups. Higher health coach engagement was associated with reduced pain interference [-0.073 per 10% increase in engagement; P < .01].</p><p><strong>Conclusions: </strong>Although no between-group differences were found, both groups showed sustained improvement in pain interference at 12 months. Personalized support may have contributed to these improvements, highlighting the value of human support within digital interventions. Further research is needed to clarify the relative contributions of digital CBT vs human support.</p><p><strong>Study registration: </strong>This trial was registered on ClinicalTrials.gov (Identifier: NCT04419168. Registered 06/05/2020).</p><p><strong>Analytic plan registration: </strong>The trial protocol and analytic plan were pre-registered and are publicly available (https://www.researchprotocols.org/2021/5/e29014).</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of physical activity on sleep in an ecologically valid design.","authors":"Sára Wolf, Róbert Bódizs, Péter Przemyslaw Ujma","doi":"10.1093/abm/kaag025","DOIUrl":"10.1093/abm/kaag025","url":null,"abstract":"<p><strong>Background: </strong>Both sleep and physical activity (PA) are essential for health. Previous studies found inconsistent effects of PA, including evening PA (EPA), on sleep.</p><p><strong>Purpose: </strong>To examine the effects of PA and its timing on objectively and subjectively measured sleep in predominantly healthy, young adults.</p><p><strong>Methods: </strong>In the Budapest Sleep, Experiences and Traits Study, a highly ecologically valid multiday observational study, 267 participants tracked their natural sleep and reported PA for at least 1 week, including mobile electroencephalography recordings. We estimated the effects of PA and its timing, quantifying it as the time elapsed between activity initiation and sleep onset.</p><p><strong>Results: </strong>Our findings showed no substantial main effect of PA on sleep (all P ≥ .19). However, PA temporally close to sleep had a rapid eye movement (REM) sleep-suppressing effect: each additional hour between PA and sleep onset decreased REM latency by 1.8 minutes (B = -1.82, SE = 0.58, P = .002) and increased REM percentage by 0.30 percentage points (B = 0.30, SE = 0.11, P = .008), but no other timing effect was found. Results were robust across multiple analytical specifications.</p><p><strong>Conclusions: </strong>Our results support neither a general sleep-promoting effect of PA nor a sleep-suppressing effect of EPA and suggest that for healthy young individuals, habitual, relatively low-intensity EPA is safe to perform and is a good alternative for those whose daily schedule permits no alternative timing, although the lack of detailed exercise intensity monitoring is a limitation of our study.</p>","PeriodicalId":520558,"journal":{"name":"Annals of behavioral medicine : a publication of the Society of Behavioral Medicine","volume":"60 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13215084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}