Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS最新文献_第5页

[Legionella prevention in intensive care units]. [重症监护病房军团菌的预防]。

IF 0.4

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Pub Date : 2004-03-01 DOI: 10.1055/s-2004-814282

I F Chaberny, S Ziesing, P Gastmeier

引用次数: 2

[Theophylline induces contractures in porcine skeletal muscle preparations with the disposition to malignant hyperthermia]. [茶碱在猪骨骼肌制剂中引起挛缩，具有恶性高热倾向]。

IF 0.4

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Pub Date : 2004-03-01 DOI: 10.1055/s-2004-814328

M U Gerbershagen, M Fiege, R Weisshorn, K Kolodzie, F Wappler

{"title":"[Theophylline induces contractures in porcine skeletal muscle preparations with the disposition to malignant hyperthermia].","authors":"M U Gerbershagen, M Fiege, R Weisshorn, K Kolodzie, F Wappler","doi":"10.1055/s-2004-814328","DOIUrl":"https://doi.org/10.1055/s-2004-814328","url":null,"abstract":"Objective: Theophylline, a methylxanthine, leads to an increase of the cytoplasmic Ca(2+)-concentration in the muscle cell. Since the in-vitro contracture test (IVCT) with halothane and caffeine does not distinguish a 100% between malignant hyperthermia susceptible (MHS) and non-susceptible (MHN), we examined the in-vitro effects of theophylline in porcine skeletal muscle preparations.Methods: After approval by the local animal care committee ten MHS- and nine MHN-swine were anaesthetized and muscle biopsies taken. For IVCT, muscle specimens were exposed to bolus administrations of theophylline in concentrations of 3.0 respectively 5.0 mmol/l. Muscle contracture development and twitch amplitudes were recorded over a period of 30 minutes. Data are expressed as medians and ranges.Results: After both theophylline bolus administrations MHS-muscles developed significantly higher contractures compared to the MHN-specimens. The MHS-muscles reached a maximum contracture of 17.0 mN (7.2-59.6 mN) after administration of 3.0 mmol/l theophylline. In comparison, two MHN-specimens showed weak contractures with a maximum of 1.4 mN. The 5.0 mmol/l theophylline IVCT resulted in maximum contractures of 19.1 mN (2.1-39.2 mN) for the MHS-preparations. Just in three MHN-muscles weak contractures of 0.0 mN (0.0-0.8 mN) were recorded. Thus, a significant difference without overlap was revealed for the maximum contracture.Conclusion: Theophylline in concentrations of 3.0 and 5.0 mmol/l revealed a clear difference between MHS- and MHN-porcine muscle preparations. Further examinations on human skeletal muscles are needed to demonstrate the value of theophylline in the IVCT MH-diagnosis.","PeriodicalId":520554,"journal":{"name":"Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS","volume":" ","pages":"147-52"},"PeriodicalIF":0.4,"publicationDate":"2004-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2004-814328","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40861413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

[Delayed onset of malignant hyperthermia crisis during a living donor liver transplantation caused by sevoflurane]. 【七氟醚致活体供肝移植恶性高热危象延迟发作】。

IF 0.4

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Pub Date : 2004-03-01 DOI: 10.1055/s-2004-814333

I Gillmeister, C Schummer, M Hommann, W Schummer

{"title":"[Delayed onset of malignant hyperthermia crisis during a living donor liver transplantation caused by sevoflurane].","authors":"I Gillmeister, C Schummer, M Hommann, W Schummer","doi":"10.1055/s-2004-814333","DOIUrl":"https://doi.org/10.1055/s-2004-814333","url":null,"abstract":"We report on a 25-year old ASA physical status I patient, who developed within 20 minutes a full-blown malignant hyperthermia (MH) in the context of a living donor liver transplantation after 180 minutes of uneventful anaesthesia. The only trigger substance applied was Sevoflurane. The patient had already received a short, uneventful anaesthesia with Isoflurane a couple of years ago. In the context of the special constellation an initial dose of Dantrolene of 10 mg/kg body weight was administered. The patient was stabilised within 30 minutes, and the enzyme levels remained low compared with other case reports. The post-operative in vitro caffeine halothane contracture testing confirmed that son and mother were susceptible to MH, contracture testing in the father was negative. All known triggers may cause life-threatening MH crisis - even after hours and after inconspicuous multiple exposures to known trigger substances. Therefore all trigger substances must be avoided in all patients susceptible to MH.","PeriodicalId":520554,"journal":{"name":"Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS","volume":" ","pages":"153-6"},"PeriodicalIF":0.4,"publicationDate":"2004-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2004-814333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40861414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

[Alternatives to endotracheal intubation: a matter of statistics?]. [替代气管插管:一个统计问题?]。

IF 0.4

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Pub Date : 2004-03-01 DOI: 10.1055/s-2004-814313

J Peters

引用次数: 1

[Warming efficacy and blood damaging of blood and infusion warmers]. 【补血温剂的温效与血损】。

IF 0.4

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Pub Date : 2004-03-01 DOI: 10.1055/s-2004-814326

O Moerer, A Bräuer, W Weyland, U Braun

{"title":"[Warming efficacy and blood damaging of blood and infusion warmers].","authors":"O Moerer, A Bräuer, W Weyland, U Braun","doi":"10.1055/s-2004-814326","DOIUrl":"https://doi.org/10.1055/s-2004-814326","url":null,"abstract":"Question: Inadequately warmed blood or infusions contribute to the development of perioperative hypothermia. Therefore we analysed the efficiency of several infusion warmers.Method: Tested infusion warmers: Model Autoline (Barkey) 500OR/241(Arizant), BW 385L(Biotest), H250/D50 und D60 (Level-1), H500/D300 (Level-1), Warmflo FW537-I/HEC40 (Tyco). Different solutions (saline, colloid solution and packed red blood cells PRBC) were tested varying the infusion flow, temperature of the solution and infusion pressure. Effective warming was defined as an infusion temperature > or = 33 degrees C. Haemolysis was measured by the increase of free plasma haemoglobin.Results: The infusion warmers were effective within the following flow ranges: Low flow rate (< 250 ml/h): Autoline, 500OR/241 and H250/D60. Medium flow rate (250-2500 ml/h): Autoline, 500OR/241, BW385L (> 480 ml/h), H250/D 60 und D50 (> or = 1300 ml/h), FW537-I/HEC40 (> 950 ml/h. High flow rate (2500-10,000 ml/h): BW385L (up to 5000 ml/h), H250/D50, H250/D60, H500/D300 and FW537-I/HEC 40(R). Highest flow rates (> 10,000 ml/h): H250/D60, H500/D300 and FW537-I HEC40. Colloidal solutions were warmed nearly as good as saline, cooled PRBC had a smaller range of effective warming. There was no relevant haemolysis in any of the tested systems (plasma free haemoglobin raise < 24 mg/dl in all systems).Conclusion: The warming capacity of the system and the length of the uninsulated infusion system determine the efficiency of an infusion warmer. The range of effective warming of an infusion warmer should be known for proper application.","PeriodicalId":520554,"journal":{"name":"Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS","volume":" ","pages":"138-46"},"PeriodicalIF":0.4,"publicationDate":"2004-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2004-814326","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40861412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Accidents with dangerous goods--how can the risks be recognized and assessed?]. 【危险品事故——如何识别和评估风险?】

IF 0.4

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Pub Date : 2004-03-01 DOI: 10.1055/s-2004-814309

R Spörri, R Walther, A Reichert, R Braun

引用次数: 0