Nanofabrication最新文献_第6页

pH-responsive cisplatin-loaded niosomes: synthesis, characterization, cytotoxicity study and interaction analyses by simulation methodology ph响应顺铂负载niosomes:合成，表征，细胞毒性研究和相互作用的模拟方法分析

IF 2.9

Nanofabrication Pub Date : 2020-01-01 DOI: 10.1515/nanofab-2020-0100

Saman Sargazi, Seyedeh Maryam Hosseinikhah, Farshid Zargari, N. Chauhana, Mohadeseh Hassanisaadi, S. Amani

{"title":"pH-responsive cisplatin-loaded niosomes: synthesis, characterization, cytotoxicity study and interaction analyses by simulation methodology","authors":"Saman Sargazi, Seyedeh Maryam Hosseinikhah, Farshid Zargari, N. Chauhana, Mohadeseh Hassanisaadi, S. Amani","doi":"10.1515/nanofab-2020-0100","DOIUrl":"https://doi.org/10.1515/nanofab-2020-0100","url":null,"abstract":"Abstract Cisplatin (Cis) is an effective cytotoxic agent, but its administration has been challenged by kidney problems, reduced immunity system, chronic neurotoxicity, and hemorrhage. To address these issues, pH-responsive non-ionic surfactant vesicles (niosomes) by Span 60 and Tween 60 derivatized by cholesteryl hemisuccinate (CHEMS), a pH-responsive agent, and Ergosterol (helper lipid), were developed for the first time to deliver Cis. The drug was encapsulated in the niosomes with a high encapsulation efficiency of 89%. This system provided a responsive release of Cis in pH 5.4 and 7.4, thereby improving its targeted anticancer drug delivery. The noisome bilayer model was studied by molecular dynamic simulation containing Tween 60, Span 60, Ergosterol, and Cis molecules to understand the interactions between the loaded drug and noisome constituents. We found that the platinum and chlorine atoms in Cis are critical factors in distributing the drug between water and bilayer surface. Finally, the lethal effect of niosomal Cis was investigated on the MCF7 breast cancer cell line using 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. Results from morphology monitoring and cytotoxic assessments suggested a better cell-killing effect for niosomal Cis than standard Cis. Together, the synthesis of stimuli-responsive niosomes could represent a promising delivery strategy for anticancer drugs.","PeriodicalId":51992,"journal":{"name":"Nanofabrication","volume":"6 1","pages":"1 - 15"},"PeriodicalIF":2.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Fabrication of Cell-Derived Biomimetic Drug Delivery System 细胞源仿生给药系统的研制

IF 2.9

Nanofabrication Pub Date : 2019-01-01 DOI: 10.1515/nanofab-2019-0001

Yi Zhou, Honghui Wu, Y. Ping, Jianqing Gao

引用次数: 5

Recent Advances in Novel DNA Guiding Nanofabrication and Nanotechnology 新型DNA引导纳米制造和纳米技术的最新进展

IF 2.9

Nanofabrication Pub Date : 2018-11-01 DOI: 10.1515/nanofab-2018-0003

Zhiguang Suo, Jingqi Chen, Ziheng Hu, Yihao Liu, Feifei Xing, Lingyan Feng

{"title":"Recent Advances in Novel DNA Guiding Nanofabrication and Nanotechnology","authors":"Zhiguang Suo, Jingqi Chen, Ziheng Hu, Yihao Liu, Feifei Xing, Lingyan Feng","doi":"10.1515/nanofab-2018-0003","DOIUrl":"https://doi.org/10.1515/nanofab-2018-0003","url":null,"abstract":"Abstract DNA as life’s genetic material has been widely investigated around the world. In recent years, with the fiery researches on nanomaterials, it also plays an important role in the development of material science due to its extraordinary molecular recognition capability and prominent structural features. In this mini review, we mainly overview the recent progresses of DNA guiding self-assembled nanostructures and nanofabrication. Typical DNA tile-based assembly and DNA origami nanotechnologies are presented, utilizing the recent 3D topology methods to fabricate multidimensional structures with unique properties. Then the site-specific nanomaterials synthesis and nano-DNA recognition on different DNA scaffolds/templates are demonstrated with excellent addressability, biocompatibility and structural programmability. Various nanomaterials, such as metals, carbon family materials, quantum dots, metal-organic frameworks, and DNA-based liquid crystals are briefly summarized. Finally, the present limitation and future promising development directions are discussed in conclusion and perspective. We wish this review would provide useful information toward the broader scientific interests in DNA nanotechnology.","PeriodicalId":51992,"journal":{"name":"Nanofabrication","volume":"4 1","pages":"32 - 52"},"PeriodicalIF":2.9,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/nanofab-2018-0003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47454938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Bio-surface engineering with DNA scaffolds for theranostic applications DNA支架生物表面工程在治疗中的应用

IF 2.9

Nanofabrication Pub Date : 2018-05-17 DOI: 10.1515/nanofab-2018-0001

Xiwei Wang, Wei Lai, Tiantian Man, Xiangmeng Qu, Li Li, A. Chandrasekaran, H. Pei

引用次数: 8

Functional Nanofibers with Multiscale Structure by Electrospinning 静电纺丝制备多尺度结构的功能性纳米纤维

IF 2.9

Nanofabrication Pub Date : 2018-05-01 DOI: 10.1515/nanofab-2018-0002

Ran Chen, Junfeng Liu, Zeyong Sun, D. Chen

引用次数: 12

Preparation and ion sensing property of the self-assembled microgels by QCM QCM自组装微凝胶的制备及其离子传感性能

IF 2.9

Nanofabrication Pub Date : 2017-12-20 DOI: 10.2478/nanofab-2017-0002

Zheng Cao, Yuyuan Chen, Qianpeng Zhang, Yanping Xia, Gang Liu, Dun Wu, Wenzhong Ma, Junfeng Cheng, Chunlin Liu

{"title":"Preparation and ion sensing property of the self-assembled microgels by QCM","authors":"Zheng Cao, Yuyuan Chen, Qianpeng Zhang, Yanping Xia, Gang Liu, Dun Wu, Wenzhong Ma, Junfeng Cheng, Chunlin Liu","doi":"10.2478/nanofab-2017-0002","DOIUrl":"https://doi.org/10.2478/nanofab-2017-0002","url":null,"abstract":"Abstract The polyanion polystyrene sulfonate (PSS), the polycation poly (allylamine hydrochloride) (PAH), and the anionic poly (N-isopropylacrylamide-co-acrylic acid) [P(NIPAM-co-AA)] microgels were self-assembled onto the polyethylene imine (PEI) adsorbed gold surfaces of quartz crystal microbalance (QCM) because of the electrostatic attractions. The interactions of various metal particles including Ca2+, Bi3+, Cu2+, Zn2+, Ni2+, Sn2+, Co2+, and Cd2+ with the obtained PEI/PSS/PAH/microgel layer in aqueous solutions were evaluated by QCM. The PEI/PSS/PAH/Microgel covered QCM sensor demonstrates the lowest detection limit of 0.1 ppm in aqueous solutions and the obviously linear connection between the frequency response and Ni2+ concentration from 0.1 to 20 ppm, which is due to the complexation of Ni2+ with the carboxyl groups of microgels. Atomic force microscopy (AFM) was used to reveal the morphology and stability of the self-assembled polyelectrolyte/microgel layer before and after adsorbing heavy metal ions. These self-assembled materials of polyelectrolyte/microgel layer will be helpful for manufacturing ion-selective materials for separation and identification purposes.","PeriodicalId":51992,"journal":{"name":"Nanofabrication","volume":"3 1","pages":"16 - 25"},"PeriodicalIF":2.9,"publicationDate":"2017-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2478/nanofab-2017-0002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43219167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Nanofabrication strategies for advanced electrode materials 先进电极材料的纳米制造策略

IF 2.9

Nanofabrication Pub Date : 2017-08-28 DOI: 10.2478/nanofab-2017-0028

Kunfeng Chen, D. Xue

{"title":"Nanofabrication strategies for advanced electrode materials","authors":"Kunfeng Chen, D. Xue","doi":"10.2478/nanofab-2017-0028","DOIUrl":"https://doi.org/10.2478/nanofab-2017-0028","url":null,"abstract":"Abstract The development of advanced electrode materials for high-performance energy storage devices becomes more and more important for growing demand of portable electronics and electrical vehicles. To speed up this process, rapid screening of exceptional materials among various morphologies, structures and sizes of materials is urgently needed. Benefitting from the advance of nanotechnology, tremendous efforts have been devoted to the development of various nanofabrication strategies for advanced electrode materials. This review focuses on the analysis of novel nanofabrication strategies and progress in the field of fast screening advanced electrode materials. The basic design principles for chemical reaction, crystallization, electrochemical reaction to control the composition and nanostructure of final electrodes are reviewed. Novel fast nanofabrication strategies, such as burning, electrochemical exfoliation, and their basic principles are also summarized. More importantly, colloid system served as one up-front design can skip over the materials synthesis, accelerating the screening rate of highperformance electrode. This work encourages us to create innovative design ideas for rapid screening high-active electrode materials for applications in energy-related fields and beyond.","PeriodicalId":51992,"journal":{"name":"Nanofabrication","volume":"3 1","pages":"1 - 15"},"PeriodicalIF":2.9,"publicationDate":"2017-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2478/nanofab-2017-0028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42945361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Nano-proximity direct ion beam writing 纳米接近直接离子束写入

IF 2.9

Nanofabrication Pub Date : 2016-01-25 DOI: 10.1515/nanofab-2015-0006

G. Seniutinas, G. Gervinskas, J. Anguita, D. Hakobyan, E. Brasselet, S. Juodkazis

引用次数: 10

Ink transport modelling in Dip-Pen Nanolithography and Polymer Pen Lithography 浸笔纳米光刻和聚合物笔光刻中的油墨传输模型

IF 2.9

Nanofabrication Pub Date : 2016-01-05 DOI: 10.1515/nanofab-2015-0005

A. Urtizberea, Michael Hirtz, H. Fuchs

引用次数: 27

Nanofabrication: Principles and Applications 纳米制造:原理与应用

IF 2.9

Nanofabrication Pub Date : 2016-01-01 DOI: 10.1007/978-3-319-31742-7

C. Papadopoulos

引用次数: 9