American journal of kidney diseases : the official journal of the National Kidney Foundation最新文献_第2页

Plasmapheresis for the treatment of severe lupus nephritis: uncontrolled observations. 血浆置换治疗严重狼疮性肾炎:非对照观察。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

E J Lewis

引用次数: 0

Proceedings of symposium: Advances in systemic lupus erythematosus. New York, New York, October 2-3, 1981. 研讨会论文集:系统性红斑狼疮的研究进展。纽约，纽约，1981年10月2-3日。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

引用次数: 0

Cytotoxic drug treatment of lupus nephritis. 细胞毒药物治疗狼疮性肾炎。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

J V Donadio, K E Holley, D M Ilstrup

引用次数: 0

Systemic lupus erythematosus in the first two decades of life. 系统性红斑狼疮发生在生命的头二十年。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

J L Platt, B A Burke, A J Fish, Y Kim, A F Michael

{"title":"Systemic lupus erythematosus in the first two decades of life.","authors":"J L Platt, B A Burke, A J Fish, Y Kim, A F Michael","doi":"","DOIUrl":"","url":null,"abstract":"Seventy patients with systemic lupus erythematosus (SLE) in the first two decades of life have been followed from 1958 to 1981. The patients were treated with corticosteroids alone (17 patients) or corticosteroids and immunosuppressives (53 patients). Twenty-one patients (30%) had evidence of CNS lupus. Eighty-seven percent of patients had evidence of renal involvement, and 34% of these patients had diffuse proliferative lupus nephritis (DPLN). A high frequency of pathologic transition was found to occur. Analysis of 20 pregnancies in 12 women with SLE reveals that patients with active SLE and/or renal disease are at a high risk for complications of pregnancy in contrast to patients in remission. The occurrence of infection, aseptic necrosis and cataracts is shown to be related to SLE itself and to its treatment. By life table analysis overall survival was 90% at 1 yr, 85% at 10 yr. and 77% at 15 yr. Survival of patients who entered the study before age 16 and of patients with CNS lupus could not be distinguished from that of the total group. Patients who entered the study from 1974-1981 had 5-yr survival similar to that of the total group. Survival of 21 patients with DPLN did not deviate from that of the entire group until 14 yr after study entry (7 yr if dialysis and transplantation are considered as deaths). In conclusion, the prognosis of SLE and especially of DPLN in the younger patient appears to be better than indicated by prior reports. Thus, analysis of outcome in this disease may require a long duration of follow-up.","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"212-22"},"PeriodicalIF":13.2,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of pregnancy in patients with SLE. 妊娠对SLE患者的影响。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

J P Hayslett

引用次数: 0

Clinical usefulness of the morphological classification of lupus nephritis. 狼疮性肾炎形态学分型的临床意义。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

D S Baldwin

{"title":"Clinical usefulness of the morphological classification of lupus nephritis.","authors":"D S Baldwin","doi":"","DOIUrl":"","url":null,"abstract":"The renal biopsy technique has made it possible to classify lupus nephritis into its varied forms. Utilizing light histology, immunofluorescence microscopy, and ultrastructural techniques, the following renal morphological manifestations of systemic lupus erythematosus can be identified: mesangial abnormalities; focal proliferative, diffuse proliferative and membranous glomerulonephritis; glomerular sclerosis; interstitial nephritis; vascular sclerosis and necrotizing renal vasculitis. Each of the morphological forms is associated with distinctive clinical features and prognosis. Mesangial and focal proliferative lupus nephritis may occur in the absence of clinical abnormalities, and in general have a favorable prognosis. Diffuse proliferative lupus nephritis often is manifested by the nephrotic syndrome and renal functional impairment which proves to be irreversible and progressive. Transition from the milder forms to diffuse proliferation occurs in about one-sixth of patients. Membranous lupus nephritis is characterized by the nephrotic syndrome, which often is persistent, but renal functional impairment develops slowly and is rarely severe. Necrotizing vasculitis, which supervenes on occasion during the course of diffuse proliferative lupus nephritis, produces the clinical picture of malignant hypertension and progresses rapidly to uremia. Interstitial nephritis usually occurs in combination with one of the glomerular forms, but at times may be the predominant renal lesion both morphologically and clinically. Glomerular sclerosis, often associated with hypertension and vascular sclerosis, commonly develops in the course of lupus nephritis, especially in the more severe forms, and may progress even though active disease has remitted. An awareness of clinico-pathologic correlations in lupus nephritis provides a basis for intelligent management and critical assessment of therapy.","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"142-9"},"PeriodicalIF":13.2,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overview of treatment of lupus nephropathy. 狼疮肾病的治疗综述。

IF 13.2

American journal of kidney diseases : the official journal of the National Kidney Foundation Pub Date : 1982-07-01

C H Coggins

引用次数: 0