{"title":"Recurrent Nephrolithiasis Causing Kidney Failure.","authors":"Amy A Yau, Judy Hindi, Jaime Uribarri","doi":"10.1053/j.ajkd.2020.04.020","DOIUrl":"https://doi.org/10.1053/j.ajkd.2020.04.020","url":null,"abstract":"A 56-year-old woman with diabetes mellitus and kidney failure treated by kidney transplantation 3 months prior is referred to your clinic for elevated serum creatinine. She gives a personal history of recurrent urinary tract infections in the setting of obstructive uropathy and recurrent nephrolithiasis. Two years ago, she developed kidney failure. Imaging at the time revealed staghorn calculi with left hydroureter (Fig 1). She underwent bilateral ureteral stent placement with some improvement in glomerular filtration rate (GFR); however, she continued to experience progressive GFR decline and required hemodialysis. At the time of planned dialysis initiation, she also underwent bilateral native nephrectomies owing to persistent pain. Pathology was significant for oxalate nephropathy with nephrolithiasis, diffuse interstitial scarring, and focal global glomerulosclerosis with intratubular birefringent calcium oxalate crystal deposits. She denies a family history of kidney disease or nephrolithiasis. After a year of treatment with dialysis, she received a living unrelated kidney transplant. One month after transplantation, she had a kidney biopsy performed for elevated serum creatinine. Kidney pathology was significant for inspissation of refractile oxalate crystals in the tubular lumina and in the cytoplasm of renal tubular cells. She was subsequently hospitalized for hyperkalemia (potassium, 5.9 mEq/L) with a serum bicarbonate of 13.6 mg/dL and serum creatinine of 1.52 mg/dL. Serum creatinine remained stable during","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"A18-A21"},"PeriodicalIF":13.2,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25507316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Broken Tumor, Intact Courage.","authors":"Dharam Kaushik","doi":"10.1053/j.ajkd.2020.11.009","DOIUrl":"https://doi.org/10.1053/j.ajkd.2020.11.009","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"A14-A15"},"PeriodicalIF":13.2,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25338589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Better Stories.","authors":"Devika Nair","doi":"10.1053/j.ajkd.2017.09.029","DOIUrl":"https://doi.org/10.1053/j.ajkd.2017.09.029","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"A10-A11"},"PeriodicalIF":13.2,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.ajkd.2017.09.029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35844385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nephrocalcinosis: A Diagnostic Conundrum.","authors":"Lalathaksha Kumbar, Jerry Yee","doi":"10.1053/j.ajkd.2017.11.025","DOIUrl":"https://doi.org/10.1053/j.ajkd.2017.11.025","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"A12-A14"},"PeriodicalIF":13.2,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.ajkd.2017.11.025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35948354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark A Lusco, Behzad Najafian, Charles E Alpers, Agnes B Fogo
{"title":"AJKD Atlas of Renal Pathology: Pierson Syndrome.","authors":"Mark A Lusco, Behzad Najafian, Charles E Alpers, Agnes B Fogo","doi":"10.1053/j.ajkd.2018.02.001","DOIUrl":"https://doi.org/10.1053/j.ajkd.2018.02.001","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"e3-e4"},"PeriodicalIF":13.2,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.ajkd.2018.02.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35948355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roel J Bolt, Janneke M B Wennink, Jonathan I M L Verbeke, Gul N Shah, William S Sly, Arend Bökenkamp
{"title":"Carbonic anhydrase type II deficiency.","authors":"Roel J Bolt, Janneke M B Wennink, Jonathan I M L Verbeke, Gul N Shah, William S Sly, Arend Bökenkamp","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"A50, e71-3"},"PeriodicalIF":13.2,"publicationDate":"2005-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25682569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quiz page. Secondary hypertension with contralateral pheochromocytoma and aldosteronoma.","authors":"Rafic F Berbarie, Michael Emmett, Neil A Breslau","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"A51, e1-3"},"PeriodicalIF":13.2,"publicationDate":"2005-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25160825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of treatment in lupus nephritis: effects of prednisone.","authors":"V E Pollak, A K Dosekun","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Survival of patients with SLE and renal disease has improved in the past 25 yr. There are numerous variables in patients with SLE, and many factors are important in determining outcome. The precise role of any therapeutic regimen in improving survival is unproven. Patients with SLE with normal kidneys, with mesangial changes or with membranous glomerulonephropathy do well whatever treatment is used. Focal and diffuse proliferative glomerulonephritis has a poor prognosis without treatment. Prednisone treatment appears to have improved the survival, but it is probable that treatment with prednisone alone may be less effective than a regimen in which it is combined with cyclophosphamide or nitrogen mustard.</p>","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"170-7"},"PeriodicalIF":13.2,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abnormal estrogen and androgen metabolism in the human with systemic lupus erythematosus.","authors":"R G Lahita, H L Bradlow, J Fishman, H G Kunkel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Humans with SLE were studied with regard to their ability to metabolize estradiol and testosterone. Significant abnormalities in the patterns of metabolism of both classes of sex steroids were found. Estradiol hydroxylation at C-16 was more extensive in both males and females with SLE -- leading to more estrogenic metabolites; and testosterone oxidation was elevated in patients with SLE resulting in a decrease in total androgens. Some normal first degree relatives of patients with SLE also had abnormalities of estradiol hydroxylation.</p>","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"206-11"},"PeriodicalIF":13.2,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Initial management of lupus glomerulonephritis.","authors":"D W Knutson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":519480,"journal":{"name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","volume":" ","pages":"229-36"},"PeriodicalIF":13.2,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}