E.I. Morgun, K.K. Sukhinich, O.S. Rogovaya, E.A. Vorotelyak
{"title":"The Model of an Ischemic Non-Healing Wound: Regeneration after Transplantation of a Living Skin Equivalent","authors":"E.I. Morgun, K.K. Sukhinich, O.S. Rogovaya, E.A. Vorotelyak","doi":"10.17691/stm2023.15.5.01","DOIUrl":"https://doi.org/10.17691/stm2023.15.5.01","url":null,"abstract":"","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"224 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined Administration of Nitric Oxide and Hydrogen into Extracorporeal Circuit of Cardiopulmonary Bypass as a Method of Organ Protection during Cardiac Surgery","authors":"V.V. Pichugin, A.V. Derugina, S.E. Domnin, A.S. Shirshin, S.A. Fedorov, S.N. Buranov, S.A. Jourko, M.V. Ryazanov, D.A. Danilova, Yu.D. Brichkin","doi":"10.17691/stm2023.15.5.02","DOIUrl":"https://doi.org/10.17691/stm2023.15.5.02","url":null,"abstract":"","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136067934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of MicroRNAs in Liver Functioning: from Biogenesis to Therapeutic Approaches (Review)","authors":"D.S. Kozlov, S.A. Rodimova, D.S. Kuznetsova","doi":"10.17691/stm2023.15.5.06","DOIUrl":"https://doi.org/10.17691/stm2023.15.5.06","url":null,"abstract":"","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optic Coherence Tomography for Accommodation Control in Children with Hyperopic Anisometropia and Amblyopia","authors":"I.L. Kulikova, K.A. Aleksandrova","doi":"10.17691/stm2023.15.5.03","DOIUrl":"https://doi.org/10.17691/stm2023.15.5.03","url":null,"abstract":"","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136067582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation Therapy for Chordomas and Chondrosarcomas of the Skull Base: Evaluation of the Effectiveness of Treatment Methods (Review)","authors":"A.A. Lemaeva, I.A. Gulidov","doi":"10.17691/stm2023.15.5.05","DOIUrl":"https://doi.org/10.17691/stm2023.15.5.05","url":null,"abstract":"","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"14 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M G Volovik, A N Belova, A N Kuznetsov, A V Polevaia, O V Vorobyova, M E Khalak
{"title":"Use of Virtual Reality Techniques to Rehabilitate Military Veterans with Post-Traumatic Stress Disorder (Review).","authors":"M G Volovik, A N Belova, A N Kuznetsov, A V Polevaia, O V Vorobyova, M E Khalak","doi":"10.17691/stm2023.15.1.08","DOIUrl":"10.17691/stm2023.15.1.08","url":null,"abstract":"<p><p>Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder developing after a traumatic event like participation in combat activities. Objective diagnosis of combat PTSD and effective rehabilitation of war veterans is a current multifaceted problem with particularly high social costs. This review aims to evaluate the potential of virtual reality technique used as exposure therapy tool (VRET) to rehabilitate combat veterans and service members with PTSD. The review was written following the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The final analysis includes 75 articles published in 2017-2022. VRET therapeutic effect mechanisms were examined along with protocols and scenarios of VRET combined with other interventions influencing PTSD treatment like pharmacotherapy, motion-assisted multi-modular memory desensitization and reconsolidation (3MDR), transcranial magnetic stimulation. The necessity is substantiated of psychophysiological measurements for objectification of PTSD clinical criteria and its dynamics during treatment. It was shown that inclusion of VRET to the package of PTSD rehabilitation interventions positively affects the results due to the enhanced effect of presence and greater experience personalization. Thus, VRET may be an effective, controlled, and cost-effective alternative for PTSD treatment in combatants, including those not responding to conventional therapy.</p>","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"15 1","pages":"74-85"},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9738052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J N Ilyushenkova, S I Sazonova, E V Popov, R E Batalov, S M Minin, A B Romanov
{"title":"Radiomic Phenotype of Periatrial Adipose Tissue in the Prognosis of Late Postablation Recurrence of Idiopathic Atrial Fibrillation.","authors":"J N Ilyushenkova, S I Sazonova, E V Popov, R E Batalov, S M Minin, A B Romanov","doi":"10.17691/stm2023.15.2.05","DOIUrl":"10.17691/stm2023.15.2.05","url":null,"abstract":"<p><p><b>The aim of the study</b> is to find new predictors of postablation atrial fibrillation (AF) recurrence in patients with lone AF using a texture analysis of the periatrial adipose tissue (PAAT) of the left atrium.</p><p><strong>Materials and methods: </strong>Forty-three patients admitted for lone AF catheter ablation, who had undergone multispiral coronary angiography, were enrolled in the study. PAAT segmentation was performed using 3D Slicer application followed by extraction of 93 radiomic features. At the end of the follow-up period, patients were divided into 2 groups depending on the presence or absence of AF recurrence.</p><p><strong>Results: </strong>12 months of follow-up after catheter ablation, postablation AF recurrence was reported in 19 out of 43 patients. Of 93 extracted radiomic features of PAAT, statistically significant differences were observed for 3 features of the Gray Level Size Zone matrix. At the same time, only one radiomic feature of PAAT, Size Zone Non Uniformity Normalized, was an independent predictor of postablative recurrence of AF after catheter ablation and 12 months of follow-up (McFadden's R<sup>2</sup>=0.451, OR - 0.506, 95% CI: 0.331‒0.776, p<0.001).</p><p><strong>Conclusion: </strong>The radiomic analysis of periatrial adipose tissue may be considered as a promising non-invasive method for predicting adverse outcomes of the catheter treatment, which opens the possibilities for planning and correction of patient management tactics after intervention.</p>","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"15 2","pages":"48-58"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9738078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D A Sirota, М О Zhulkov, D S Khvan, T Caus, B N Kozlov, V L Lukinov, М М Lyashenko, A G Makaev, A V Protopopov, Kh A Agaeva, A V Fomichev, S A Мagbulova, A D Limansky, A М Chernyavsky
{"title":"Predictors of Lethality, Remodeling, and Aorta-Related Events in Different Types of Proximal Aortic Dissection Surgery.","authors":"D A Sirota, М О Zhulkov, D S Khvan, T Caus, B N Kozlov, V L Lukinov, М М Lyashenko, A G Makaev, A V Protopopov, Kh A Agaeva, A V Fomichev, S A Мagbulova, A D Limansky, A М Chernyavsky","doi":"10.17691/stm2023.15.1.05","DOIUrl":"10.17691/stm2023.15.1.05","url":null,"abstract":"<p><p><b>The aim of the study</b> is to analyze predictors of lethality, false lumen thrombosis, enlargement of aortic diameter, and frequency of aorta-related events in the early and remote postoperative periods for various types of proximal aortic dissection surgery using the logistic regression method.</p><p><strong>Materials and methods: </strong>A retrospective observational comparison of the results of surgical treatment of 213 patients with the diagnosis of \"DeBakey type I aortic dissection\" has been carried out. The participants were divided into three groups: group 1 underwent classic aortic arch reconstruction using hemiarch technique or total reconstruction of the aortic arch with a multiple-branch prosthesis (n=121); group 2 was subjected to the hemiarch technique and implantation of bare-metal (uncoated) stents (n=55); in group 3, the \"frozen elephant trunk\" correction technique was used (n=37). The diagnosis of all patients included into the study was preoperatively confirmed by ultrasound and tomographic examination. Predictors of negative events have been identified by building the models of logistic regressions.</p><p><strong>Results: </strong>The multivariate model of logistic regression has revealed multiplicative significant predictors of lethality: postoperative neurological complications increased the probability of lethality by 3.39 (1.24-9.18) times and presence of a patent false lumen by 4.17 (1.49-13.68) times.Among the predictors of aorta-related events, the most important were connective tissue diseases (the probability increased by 6.68 (2.98-15.62) times), presence of partial thrombosis of the false lumen (the probability of event development increased by 2.39 (1.07-5.44) times), and aortic valve repair (the probability aorta-event occurrence increased by 2.84 (1.13-7.17) times).Hybrid prosthesis implantation appeared to be the most significant predictor of false lumen thrombosis increasing its probability by 4.19 (1.90-9.44) times among aortic repair methods, while a bare-metal stent implantation in contrast reduced the likelihood of false lumen thrombosis by 0.17 (0.03-0.62) times. Eventually, the type of repair had not any significant impact on the aorta-related events and lethality in the long-term period.</p>","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"15 1","pages":"38-50"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10127413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A G Velichanskaya, М L Bugrova, E V Pogadaeva, E A Ermolina, A V Yudintsev, I L Ermolin
{"title":"Sciatic Nerve Plastic Surgery using Autologous Adipose Tissue.","authors":"A G Velichanskaya, М L Bugrova, E V Pogadaeva, E A Ermolina, A V Yudintsev, I L Ermolin","doi":"10.17691/stm2023.15.1.04","DOIUrl":"10.17691/stm2023.15.1.04","url":null,"abstract":"<p><p><b>The aim of the investigation</b> is to study structural alterations of autologous omental adipose tissue in a silicon conduit and to evaluate its possible use for regeneration of the sciatic nerve in diastasis.</p><p><strong>Materials and methods: </strong>Mature outbred male Wistar rats have been used in the study. The animals were divided into 7 experimental groups with complete transection of the sciatic nerve on the right side at the mid-third level of the thigh. The ends of the transected nerve were pulled apart, inserted into a silicon conduit, and secured to the epineurium. The conduit of group 1 (control) was filled with a saline solution; in group 2, it was filled with an autologous omental adipose tissue with saline solution. Intravital labeling of the omental adipose tissue with the lipophilic PKH 26 dye (in group 3) was used for the first time to find out whether the omental cells were involved in formation of the regenerating nerve. Diastasis in groups 1-3 was 5 mm, the postoperative period was 14 weeks. The dynamics of the omental adipose tissue changes in groups 4-7 was assessed by placing the omental tissues into the conduit covering 2 mm of diastasis. The postoperative period was 4, 14, 21, and 42 weeks.</p><p><strong>Results: </strong>In group 2 (omental adipose tissue + saline), the clinical condition of the damaged limb after 14 weeks may be evaluated as satisfactory and approximating to the intact parameters as compared to group 1 where the conduit was filled with a saline solution only. The sum of large and medium-sized nerve fibers in group 2 was 2.7 times greater than that in group 2. The milled omental adipose tissue inside the conduit changed its volume and structure in nerve diastasis and was constantly utilized up to complete elimination over time. The omental cells integrated into the newly formed nerve in the graft area.</p><p><strong>Conclusion: </strong>As a graft, the adipose tissue of the autologous omentum produces a stimulating effect on the post-traumatic regeneration of the sciatic nerve.</p>","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":"15 1","pages":"30-36"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9736079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}